Sun3 (Sad1 and UNC84 domain containing 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sun3 (Sad1 and UNC84 domain containing 3) Mus musculus
Analyze
Symbol: Sun3
Name: Sad1 and UNC84 domain containing 3
RGD ID: 1614216
MGI Page MGI
Description: Predicted to enable protein-membrane adaptor activity. Part of meiotic nuclear membrane microtubule tethering complex. Orthologous to human SUN3 (Sad1 and UNC84 domain containing 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D630047F21Rik; MGC130135; RP23-219P13.2; Sad1 and UNC84 domain containing 1; Sad1 and UNC84 domain-containing protein 3; sad1/unc-84 domain-containing protein 1; Sun; SUN domain-containing protein 3; Sunc1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39118,962,704 - 8,998,991 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl118,966,054 - 8,998,991 (-)EnsemblGRCm39 Ensembl
GRCm38119,016,043 - 9,048,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,016,054 - 9,048,991 (-)EnsemblGRCm38mm10GRCm38
MGSCv37118,916,057 - 8,948,994 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36118,916,057 - 8,948,994 (-)NCBIMGSCv36mm8
Celera119,448,424 - 9,486,332 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map115.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:20711465   PMID:21873635   PMID:32156700  


Genomics

Comparative Map Data
Sun3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39118,962,704 - 8,998,991 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl118,966,054 - 8,998,991 (-)EnsemblGRCm39 Ensembl
GRCm38119,016,043 - 9,048,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,016,054 - 9,048,991 (-)EnsemblGRCm38mm10GRCm38
MGSCv37118,916,057 - 8,948,994 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36118,916,057 - 8,948,994 (-)NCBIMGSCv36mm8
Celera119,448,424 - 9,486,332 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map115.77NCBI
SUN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38747,987,148 - 48,035,902 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl747,987,148 - 48,029,119 (-)EnsemblGRCh38hg38GRCh38
GRCh37748,026,745 - 48,068,704 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36747,993,270 - 48,035,241 (-)NCBINCBI36Build 36hg18NCBI36
Build 34747,799,993 - 47,841,944NCBI
Celera748,126,024 - 48,167,993 (-)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef747,912,236 - 47,954,201 (-)NCBIHuRef
CHM1_1748,030,470 - 48,072,418 (-)NCBICHM1_1
T2T-CHM13v2.0748,149,392 - 48,198,144 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2748,066,697 - 48,108,669 (-)NCBI
Sun3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81487,923,891 - 87,962,699 (-)NCBIGRCr8
mRatBN7.21483,710,136 - 83,748,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1483,710,140 - 83,735,830 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01489,215,386 - 89,253,585 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1489,215,703 - 89,238,094 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01489,012,900 - 89,050,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41489,549,426 - 89,573,888 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1482,746,240 - 82,785,252 (-)NCBICelera
Cytogenetic Map14q21NCBI
Sun3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554565,423,920 - 5,445,741 (+)NCBIChiLan1.0ChiLan1.0
SUN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2652,863,884 - 52,964,433 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17101,188,617 - 101,287,849 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0748,629,697 - 48,728,738 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1748,738,436 - 48,779,798 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl748,738,493 - 48,779,798 (-)Ensemblpanpan1.1panPan2
SUN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11837,469 - 73,849 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1836,691 - 73,805 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha184,358 - 40,701 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01870,108 - 106,446 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1883,513 - 106,407 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11845,001 - 81,339 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01847,762 - 84,126 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.018182,978 - 219,324 (-)NCBIUU_Cfam_GSD_1.0
Sun3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118103,208,901 - 103,247,783 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647822,420,820 - 22,452,780 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647822,420,673 - 22,452,780 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,485,037 - 48,519,230 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,484,700 - 48,519,311 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SUN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12110,769,668 - 10,813,071 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2110,769,884 - 10,812,890 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606211,416,110 - 11,463,121 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sun3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247405,557,581 - 5,585,549 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247405,555,412 - 5,590,876 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sun3
1579 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:161
Count of miRNA genes:81
Interacting mature miRNAs:84
Transcripts:ENSMUST00000043377, ENSMUST00000102909
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11450789621379532Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226794Feml9_mfemur length 9, 5 week (mouse)11705000016750000Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse

Markers in Region
D11Mit62  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38119,026,225 - 9,026,374UniSTSGRCm38
MGSCv37118,926,228 - 8,926,377UniSTSGRCm37
Celera119,458,226 - 9,458,375UniSTS
Cytogenetic Map11A1UniSTS
cM Map111.5UniSTS
Whitehead Genetic112.2UniSTS
Whitehead_YAC11 UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000043377   ⟹   ENSMUSP00000045199
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,966,054 - 8,989,589 (-)Ensembl
GRCm38.p6 Ensembl119,016,054 - 9,039,589 (-)Ensembl
RefSeq Acc Id: ENSMUST00000102909   ⟹   ENSMUSP00000099973
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,966,054 - 8,998,991 (-)Ensembl
GRCm38.p6 Ensembl119,016,054 - 9,048,991 (-)Ensembl
RefSeq Acc Id: NM_001290519   ⟹   NP_001277448
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,966,054 - 8,989,591 (-)NCBI
GRCm38119,016,054 - 9,039,591 (-)NCBI
Celera119,448,424 - 9,486,332 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001290520   ⟹   NP_001277449
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,966,054 - 8,998,991 (-)NCBI
GRCm38119,016,054 - 9,048,991 (-)NCBI
Celera119,448,424 - 9,486,332 (-)NCBI
Sequence:
RefSeq Acc Id: NM_177576   ⟹   NP_808244
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,966,054 - 8,998,991 (-)NCBI
GRCm38119,016,054 - 9,048,991 (-)NCBI
MGSCv37118,916,057 - 8,948,994 (-)RGD
Celera119,448,424 - 9,486,332 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006514595   ⟹   XP_006514658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,966,043 - 8,989,478 (-)NCBI
GRCm38119,016,043 - 9,039,485 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006514597   ⟹   XP_006514660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,962,704 - 8,998,541 (-)NCBI
GRCm38119,016,054 - 9,048,541 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006514598   ⟹   XP_006514661
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,972,354 - 8,989,508 (-)NCBI
GRCm38119,022,354 - 9,039,508 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245703   ⟹   XP_030101563
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,966,052 - 8,998,483 (-)NCBI
GRCm38119,016,054 - 9,048,483 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156457   ⟹   XP_036012350
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,966,052 - 8,998,062 (-)NCBI
Sequence:
RefSeq Acc Id: NP_808244   ⟸   NM_177576
- Peptide Label: isoform b
- UniProtKB: Q5SS91 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006514658   ⟸   XM_006514595
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006514660   ⟸   XM_006514597
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006514661   ⟸   XM_006514598
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001277449   ⟸   NM_001290520
- Peptide Label: isoform b
- UniProtKB: Q5SS91 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277448   ⟸   NM_001290519
- Peptide Label: isoform a
- UniProtKB: Q8BHY0 (UniProtKB/Swiss-Prot),   Q5SS91 (UniProtKB/Swiss-Prot),   E9LV81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101563   ⟸   XM_030245703
- Peptide Label: isoform X4
RefSeq Acc Id: ENSMUSP00000099973   ⟸   ENSMUST00000102909
RefSeq Acc Id: ENSMUSP00000045199   ⟸   ENSMUST00000043377
RefSeq Acc Id: XP_036012350   ⟸   XM_036156457
- Peptide Label: isoform X4
Protein Domains
SUN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5SS91-F1-model_v2 AlphaFold Q5SS91 1-320 view protein structure

Promoters
RGD ID:6822260
Promoter ID:MM_KWN:6422
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:NM_177576
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36118,948,661 - 8,949,161 (-)MPROMDB
RGD ID:8673946
Promoter ID:EPDNEW_M15003
Type:initiation region
Name:Sun3_2
Description:Mus musculus Sad1 and UNC84 domain containing 3 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15005  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38119,039,591 - 9,039,651EPDNEW
RGD ID:8673948
Promoter ID:EPDNEW_M15005
Type:single initiation site
Name:Sun3_1
Description:Mus musculus Sad1 and UNC84 domain containing 3 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15003  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38119,048,983 - 9,049,043EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3041199 AgrOrtholog
Ensembl Genes ENSMUSG00000040985 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000043377 ENTREZGENE
  ENSMUST00000043377.6 UniProtKB/Swiss-Prot
  ENSMUST00000102909 ENTREZGENE
  ENSMUST00000102909.8 UniProtKB/Swiss-Prot
Gene3D-CATH Galactose-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro SUN1-5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:194974 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:3041199 ENTREZGENE
NCBI Gene 194974 ENTREZGENE
PANTHER PTHR12911 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12911:SF24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sad1_UNC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sun3 PhenoGen
PROSITE SUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9LV81 ENTREZGENE, UniProtKB/TrEMBL
  Q5SS91 ENTREZGENE
  Q8BHY0 ENTREZGENE
  SUN3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8BHY0 UniProtKB/Swiss-Prot