Trarg1 (trafficking regulator of GLUT4 (SLC2A4) 1) - Rat Genome Database
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Gene: Trarg1 (trafficking regulator of GLUT4 (SLC2A4) 1) Mus musculus
Analyze
Symbol: Trarg1
Name: trafficking regulator of GLUT4 (SLC2A4) 1
RGD ID: 1614153
MGI Page MGI
Description: Involved in endosome to plasma membrane protein transport; glucose import in response to insulin stimulus; and vesicle fusion to plasma membrane. Localizes to cytoplasmic vesicle membrane; perinuclear region of cytoplasm; and plasma membrane. Is expressed in dorsal root ganglion; lung; trigeminal ganglion; and white fat. Orthologous to human TRARG1 (trafficking regulator of GLUT4 (SLC2A4) 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; buta-1,3-diene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C130069F04Rik; dispanin subfamily B member 1; DSPB1; LO; Lost1; RP23-343C18.2; trafficking regulator of GLUT4 1; tumor suppressor candidate 5; tumor suppressor candidate 5 homolog; Tusc; Tusc5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,570,699 - 76,589,490 (+)NCBIGRCm39mm39
GRCm381176,679,873 - 76,698,664 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,679,808 - 76,698,664 (+)EnsemblGRCm38mm10GRCm38
MGSCv371176,493,375 - 76,512,166 (+)NCBIGRCm37mm9NCBIm37
MGSCv361176,496,068 - 76,514,857 (+)NCBImm8
Celera1184,185,050 - 84,203,799 (+)NCBICelera
Cytogenetic Map11B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17689857   PMID:21677750  
PMID:21873635   PMID:22363774   PMID:26240143   PMID:26629404   PMID:29787242  


Genomics

Comparative Map Data
Trarg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,570,699 - 76,589,490 (+)NCBIGRCm39mm39
GRCm381176,679,873 - 76,698,664 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,679,808 - 76,698,664 (+)EnsemblGRCm38mm10GRCm38
MGSCv371176,493,375 - 76,512,166 (+)NCBIGRCm37mm9NCBIm37
MGSCv361176,496,068 - 76,514,857 (+)NCBImm8
Celera1184,185,050 - 84,203,799 (+)NCBICelera
Cytogenetic Map11B5NCBI
TRARG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl171,279,662 - 1,300,978 (+)EnsemblGRCh38hg38GRCh38
GRCh38171,279,662 - 1,300,978 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37171,182,956 - 1,204,272 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37171,182,957 - 1,204,281 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,129,707 - 1,151,031 (+)NCBINCBI36hg18NCBI36
Build 34171,129,706 - 1,151,031NCBI
Celera171,196,900 - 1,218,026 (+)NCBI
Cytogenetic Map17p13.3NCBI
HuRef171,086,165 - 1,107,345 (+)NCBIHuRef
CHM1_1171,191,808 - 1,212,860 (+)NCBICHM1_1
Trarg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21061,521,107 - 61,541,494 (+)NCBI
Rnor_6.0 Ensembl1063,471,331 - 63,491,713 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01063,471,330 - 63,491,713 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01063,170,005 - 63,190,291 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41067,473,506 - 67,502,184 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11067,489,278 - 67,515,794 (-)NCBI
Celera1060,534,704 - 60,553,384 (+)NCBICelera
Cytogenetic Map10q24NCBI
Trarg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,775,426 - 2,791,997 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,775,426 - 2,789,929 (+)NCBIChiLan1.0ChiLan1.0
TRARG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1171,162,442 - 1,186,181 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,162,442 - 1,186,181 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0171,262,220 - 1,286,565 (+)NCBIMhudiblu_PPA_v0panPan3
TRARG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl944,563,419 - 44,576,972 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1944,560,962 - 44,577,418 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Trarg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365386,534,704 - 6,551,335 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRARG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11246,623,712 - 46,634,115 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21248,713,393 - 48,723,972 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRARG1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116981,216 - 998,973 (+)NCBI
Trarg1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247863,036,968 - 3,048,817 (-)NCBI

Position Markers
BB373192  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,698,452 - 76,698,537UniSTSGRCm38
MGSCv371176,511,954 - 76,512,039UniSTSGRCm37
Celera1184,203,587 - 84,203,672UniSTS
Cytogenetic Map11B5UniSTS
Whitehead/MRC_RH11960.32UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1047
Count of miRNA genes:539
Interacting mature miRNAs:677
Transcripts:ENSMUST00000062024
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000062024   ⟹   ENSMUSP00000061634
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1176,679,808 - 76,698,664 (+)Ensembl
RefSeq Acc Id: NM_177709   ⟹   NP_808377
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,570,699 - 76,589,490 (+)NCBI
GRCm381176,679,873 - 76,698,664 (+)ENTREZGENE
MGSCv371176,493,375 - 76,512,166 (+)RGD
Celera1184,185,050 - 84,203,799 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_808377   ⟸   NM_177709
- UniProtKB: Q8C838 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000061634   ⟸   ENSMUST00000062024

Promoters
RGD ID:8675608
Promoter ID:EPDNEW_M15835
Type:initiation region
Name:Tusc5_1
Description:Mus musculus tumor suppressor candidate 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381176,679,779 - 76,679,839EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3029307 AgrOrtholog
Ensembl Genes ENSMUSG00000046275 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000061634 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000062024 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro CD225/Dispanin_fam UniProtKB/Swiss-Prot
KEGG Report mmu:237858 UniProtKB/Swiss-Prot
MGD MGI:3029307 ENTREZGENE
NCBI Gene 237858 ENTREZGENE
Pfam CD225 UniProtKB/Swiss-Prot
PhenoGen Trarg1 PhenoGen
UniProt Q8C838 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-14 Trarg1  trafficking regulator of GLUT4 (SLC2A4) 1  Tusc5  tumor suppressor candidate 5  Symbol and/or name change 5135510 APPROVED