Hfm1 (HFM1, ATP-dependent DNA helicase homolog) - Rat Genome Database

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Gene: Hfm1 (HFM1, ATP-dependent DNA helicase homolog) Mus musculus
Analyze
Symbol: Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
RGD ID: 1614052
MGI Page MGI
Description: Predicted to enable DNA helicase activity. Acts upstream of or within resolution of meiotic recombination intermediates. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 9. Orthologous to human HFM1 (helicase for meiosis 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A330009G12Rik; Gm1046; Mer; Mer3; probable ATP-dependent DNA helicase HFM1; SEC63 domain containing 1; Sec63d; Sec63d1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395106,988,059 - 107,074,427 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5106,988,058 - 107,074,187 (-)EnsemblGRCm39 Ensembl
GRCm385106,840,193 - 106,926,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5106,840,192 - 106,926,321 (-)EnsemblGRCm38mm10GRCm38
MGSCv375107,269,216 - 107,354,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365107,142,191 - 107,166,192 (-)NCBIMGSCv36mm8
Celera5103,958,350 - 104,043,607 (-)NCBICelera
Cytogenetic Map5E5NCBI
cM Map551.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635   PMID:23555294  
PMID:25892231   PMID:27739607   PMID:28051769   PMID:31019073   PMID:31146259   PMID:32606310   PMID:35526155  


Genomics

Comparative Map Data
Hfm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395106,988,059 - 107,074,427 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5106,988,058 - 107,074,187 (-)EnsemblGRCm39 Ensembl
GRCm385106,840,193 - 106,926,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5106,840,192 - 106,926,321 (-)EnsemblGRCm38mm10GRCm38
MGSCv375107,269,216 - 107,354,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365107,142,191 - 107,166,192 (-)NCBIMGSCv36mm8
Celera5103,958,350 - 104,043,607 (-)NCBICelera
Cytogenetic Map5E5NCBI
cM Map551.43NCBI
HFM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,260,766 - 91,408,007 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,260,766 - 91,404,856 (-)EnsemblGRCh38hg38GRCh38
GRCh37191,726,323 - 91,870,394 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,498,911 - 91,643,014 (-)NCBINCBI36Build 36hg18NCBI36
Celera189,974,186 - 90,118,312 (-)NCBICelera
Cytogenetic Map1p22.2NCBI
HuRef189,845,547 - 89,989,669 (-)NCBIHuRef
CHM1_1191,841,173 - 91,985,260 (-)NCBICHM1_1
T2T-CHM13v2.0191,105,413 - 91,252,636 (-)NCBIT2T-CHM13v2.0
Hfm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8143,002,103 - 3,108,567 (+)NCBIGRCr8
mRatBN7.2142,857,251 - 2,943,766 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl142,856,599 - 2,939,238 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx142,738,710 - 2,817,281 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0144,040,205 - 4,118,784 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0142,740,225 - 2,818,798 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0143,879,172 - 3,961,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,882,398 - 3,960,909 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0143,876,228 - 3,958,179 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4143,477,851 - 3,556,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera142,875,579 - 2,955,062 (+)NCBICelera
Cytogenetic Map14p22NCBI
Hfm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554232,993,682 - 3,089,024 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554232,993,723 - 3,088,391 (+)NCBIChiLan1.0ChiLan1.0
HFM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21135,625,418 - 135,762,746 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11134,782,877 - 134,917,758 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,923,279 - 94,058,194 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1192,669,768 - 92,802,528 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl192,669,768 - 92,802,528 (-)Ensemblpanpan1.1panPan2
HFM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1657,403,006 - 57,541,616 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl657,403,471 - 57,534,615 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha660,107,979 - 60,257,033 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0657,785,587 - 57,935,671 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl657,819,298 - 57,918,158 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1657,461,604 - 57,610,980 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0657,436,714 - 57,576,808 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0657,900,647 - 58,050,087 (+)NCBIUU_Cfam_GSD_1.0
Hfm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058101,259,251 - 101,341,922 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365377,606,025 - 7,741,219 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HFM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4125,522,334 - 125,606,882 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14125,522,300 - 125,614,296 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24137,103,085 - 137,187,996 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103224451
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12041,837,289 - 41,957,302 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366619455,576 - 137,417 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hfm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247426,394,790 - 6,513,601 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hfm1
2811 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1070
Count of miRNA genes:545
Interacting mature miRNAs:644
Transcripts:ENSMUST00000112690, ENSMUST00000117588, ENSMUST00000134292, ENSMUST00000148495, ENSMUST00000148686, ENSMUST00000155171
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
10045978Tir10_mtrypanosome infection response 10 (mouse)Not determined598019649114021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
1301877Bbaa3_mB.burgdorferi-associated arthritis 3 (mouse)Not determined599455285112465722Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5103047866115538059Mouse
25314317Sccor3_msynaptonemal complex length to mean MLH1 count ratio 3 (mouse)5104347866114738061Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
1357886Diht_mdopamine-induced hypothermia (mouse)Not determined5104498738115101540Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse

Markers in Region
12.MMHAP17FRD9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385106,858,993 - 106,859,156UniSTSGRCm38
MGSCv375107,288,012 - 107,288,175UniSTSGRCm37
Celera5103,977,149 - 103,977,312UniSTS
Cytogenetic Map5E5UniSTS
Whitehead_YAC5 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001784708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001784709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001784710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003955663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003955664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003955665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003955666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003955667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC137947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC172050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC172051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC172061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000112690   ⟹   ENSMUSP00000108310
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5106,988,063 - 107,073,756 (-)Ensembl
GRCm38.p6 Ensembl5106,840,197 - 106,925,890 (-)Ensembl
RefSeq Acc Id: ENSMUST00000117588   ⟹   ENSMUSP00000112590
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5106,988,060 - 107,074,187 (-)Ensembl
GRCm38.p6 Ensembl5106,840,194 - 106,926,321 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134292
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5107,049,753 - 107,074,124 (-)Ensembl
GRCm38.p6 Ensembl5106,901,887 - 106,926,258 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148495   ⟹   ENSMUSP00000122169
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5106,988,058 - 107,043,193 (-)Ensembl
GRCm38.p6 Ensembl5106,840,192 - 106,895,327 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148686   ⟹   ENSMUSP00000120112
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5107,049,753 - 107,073,756 (-)Ensembl
GRCm38.p6 Ensembl5106,901,887 - 106,925,890 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155171   ⟹   ENSMUSP00000118674
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5106,989,428 - 107,037,788 (-)Ensembl
GRCm38.p6 Ensembl5106,841,562 - 106,889,922 (-)Ensembl
RefSeq Acc Id: ENSMUST00000200249   ⟹   ENSMUSP00000142727
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5107,049,937 - 107,073,718 (-)Ensembl
GRCm38.p6 Ensembl5106,902,071 - 106,925,852 (-)Ensembl
RefSeq Acc Id: NM_001252516   ⟹   NP_001239445
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395107,049,753 - 107,073,726 (-)NCBI
GRCm385106,901,889 - 106,925,890 (-)NCBI
Celera5103,958,350 - 104,043,607 (-)ENTREZGENE
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001412542   ⟹   NP_001399471
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,062 - 107,074,427 (-)NCBI
RefSeq Acc Id: NM_001412561   ⟹   NP_001399490
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,062 - 107,074,128 (-)NCBI
RefSeq Acc Id: NM_001412562   ⟹   NP_001399491
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,062 - 107,074,128 (-)NCBI
RefSeq Acc Id: NM_177873   ⟹   NP_808541
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,062 - 107,073,726 (-)NCBI
GRCm385106,840,197 - 106,925,890 (-)NCBI
MGSCv375107,269,216 - 107,354,909 (-)RGD
Celera5103,958,350 - 104,043,607 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006535015   ⟹   XP_006535078
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,073,983 (-)NCBI
GRCm385106,840,193 - 106,926,117 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535016   ⟹   XP_006535079
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,401 (-)NCBI
GRCm385106,840,193 - 106,926,536 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249487   ⟹   XP_011247789
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254590   ⟹   XP_030110450
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,162 (-)NCBI
GRCm385106,840,193 - 106,926,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254591   ⟹   XP_030110451
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,162 (-)NCBI
GRCm385106,840,193 - 106,926,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254593   ⟹   XP_030110453
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254594   ⟹   XP_030110454
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254595   ⟹   XP_030110455
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254596   ⟹   XP_030110456
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254597   ⟹   XP_030110457
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254598   ⟹   XP_030110458
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254599   ⟹   XP_030110459
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,073,982 (-)NCBI
GRCm385106,840,193 - 106,926,116 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254600   ⟹   XP_030110460
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165227   ⟹   XP_036021120
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165228   ⟹   XP_036021121
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001784708
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001784709
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,059 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001784710
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395107,049,636 - 107,073,983 (-)NCBI
GRCm385106,898,258 - 106,926,117 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003955663
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,491 - 107,074,143 (-)NCBI
GRCm385106,840,625 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003955664
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,988,382 - 107,074,143 (-)NCBI
GRCm385106,840,193 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003955665
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,995,601 - 107,074,143 (-)NCBI
GRCm385106,847,735 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003955666
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395106,998,488 - 107,074,143 (-)NCBI
GRCm385106,850,622 - 106,926,277 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003955667
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395107,046,124 - 107,074,162 (-)NCBI
GRCm385106,898,258 - 106,926,296 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001239445 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399471 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399490 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399491 (Get FASTA)   NCBI Sequence Viewer  
  NP_808541 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535078 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535079 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247789 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110450 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110451 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110453 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110454 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110455 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110456 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110457 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110458 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110459 (Get FASTA)   NCBI Sequence Viewer  
  XP_030110460 (Get FASTA)   NCBI Sequence Viewer  
  XP_036021120 (Get FASTA)   NCBI Sequence Viewer  
  XP_036021121 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI72050 (Get FASTA)   NCBI Sequence Viewer  
  AAI72051 (Get FASTA)   NCBI Sequence Viewer  
  AAI72061 (Get FASTA)   NCBI Sequence Viewer  
  BAC30299 (Get FASTA)   NCBI Sequence Viewer  
  D3Z4R1 (Get FASTA)   NCBI Sequence Viewer  
  EDL20175 (Get FASTA)   NCBI Sequence Viewer  
  EDL20176 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000108310
  ENSMUSP00000108310.4
  ENSMUSP00000112590.2
  ENSMUSP00000118674.2
  ENSMUSP00000120112.2
  ENSMUSP00000122169.2
  ENSMUSP00000142727.2
Reference Protein Sequences
RefSeq Acc Id: NP_808541   ⟸   NM_177873
- Peptide Label: isoform 1
- UniProtKB: D3Z4R1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001239445   ⟸   NM_001252516
- Peptide Label: isoform 2
- UniProtKB: Q8CA92 (UniProtKB/TrEMBL),   D3YUB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006535079   ⟸   XM_006535016
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006535078   ⟸   XM_006535015
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011247789   ⟸   XM_011249487
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_030110451   ⟸   XM_030254591
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030110450   ⟸   XM_030254590
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030110456   ⟸   XM_030254596
- Peptide Label: isoform X9
RefSeq Acc Id: XP_030110453   ⟸   XM_030254593
- Peptide Label: isoform X5
RefSeq Acc Id: XP_030110458   ⟸   XM_030254598
- Peptide Label: isoform X10
RefSeq Acc Id: XP_030110460   ⟸   XM_030254600
- Peptide Label: isoform X10
RefSeq Acc Id: XP_030110455   ⟸   XM_030254595
- Peptide Label: isoform X7
RefSeq Acc Id: XP_030110457   ⟸   XM_030254597
- Peptide Label: isoform X10
RefSeq Acc Id: XP_030110454   ⟸   XM_030254594
- Peptide Label: isoform X6
RefSeq Acc Id: XP_030110459   ⟸   XM_030254599
- Peptide Label: isoform X10
RefSeq Acc Id: ENSMUSP00000108310   ⟸   ENSMUST00000112690
RefSeq Acc Id: ENSMUSP00000122169   ⟸   ENSMUST00000148495
RefSeq Acc Id: ENSMUSP00000120112   ⟸   ENSMUST00000148686
RefSeq Acc Id: ENSMUSP00000112590   ⟸   ENSMUST00000117588
RefSeq Acc Id: ENSMUSP00000118674   ⟸   ENSMUST00000155171
RefSeq Acc Id: ENSMUSP00000142727   ⟸   ENSMUST00000200249
RefSeq Acc Id: XP_036021121   ⟸   XM_036165228
- Peptide Label: isoform X10
RefSeq Acc Id: XP_036021120   ⟸   XM_036165227
- Peptide Label: isoform X10
RefSeq Acc Id: NP_001399471   ⟸   NM_001412542
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001399491   ⟸   NM_001412562
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001399490   ⟸   NM_001412561
- Peptide Label: isoform 4
Protein Domains
DEAD/DEAH box helicase   Helicase ATP-binding   Helicase C-terminal   SEC63

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z4R1-F1-model_v2 AlphaFold D3Z4R1 1-1434 view protein structure

Promoters
RGD ID:6887402
Promoter ID:EPDNEW_M7152
Type:initiation region
Name:Hfm1_1
Description:Mus musculus HFM1, ATP-dependent DNA helicase homolog , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385106,925,851 - 106,925,911EPDNEW
RGD ID:6837695
Promoter ID:MM_KWN:43216
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:ENSMUST00000117588,   NM_177873,   OTTMUST00000069726,   OTTMUST00000069727
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365107,354,956 - 107,355,456 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3036246 AgrOrtholog
Ensembl Genes ENSMUSG00000043410 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112690 ENTREZGENE
  ENSMUST00000112690.10 UniProtKB/Swiss-Prot
  ENSMUST00000117588.8 UniProtKB/Swiss-Prot
  ENSMUST00000148495.2 UniProtKB/TrEMBL
  ENSMUST00000148686.8 UniProtKB/TrEMBL
  ENSMUST00000155171.2 UniProtKB/TrEMBL
  ENSMUST00000200249.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec63 N-terminal domain-like domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec63-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report mmu:330149 UniProtKB/Swiss-Prot
MGD MGI:3036246 ENTREZGENE
NCBI Gene 330149 ENTREZGENE
PANTHER HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC63 DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DEAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot
  Sec63 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hfm1 PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/Swiss-Prot
SMART DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
  Sec63 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Sec63 N-terminal domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF46785 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JED3_MOUSE UniProtKB/TrEMBL
  B7ZWH2_MOUSE UniProtKB/TrEMBL
  B7ZWH3_MOUSE UniProtKB/TrEMBL
  B7ZWI0_MOUSE UniProtKB/TrEMBL
  D3YUB5 ENTREZGENE
  D3Z4R1 ENTREZGENE
  D6RJK3_MOUSE UniProtKB/TrEMBL
  F6XQ35_MOUSE UniProtKB/TrEMBL
  F7C082_MOUSE UniProtKB/TrEMBL
  HFM1_MOUSE UniProtKB/Swiss-Prot
  Q8CA92 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary D3YUB5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Hfm1  HFM1, ATP-dependent DNA helicase homolog    HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED