Slc22a14 (solute carrier family 22 (organic cation transporter), member 14) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Slc22a14 (solute carrier family 22 (organic cation transporter), member 14) Mus musculus
Analyze
Symbol: Slc22a14
Name: solute carrier family 22 (organic cation transporter), member 14
RGD ID: 1614018
MGI Page MGI
Description: Orthologous to human SLC22A14 (solute carrier family 22 member 14); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gm1128; MGC118292; organic cation transporter like 4; solute carrier family 22 member 14
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,998,521 - 119,019,496 (-)NCBIGRCm39mm39
GRCm389119,169,453 - 119,190,430 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,169,455 - 119,365,553 (-)EnsemblGRCm38mm10GRCm38
MGSCv379119,078,574 - 119,099,511 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,018,154 - 119,039,091 (-)NCBImm8
Celera9119,637,344 - 119,658,281 (-)NCBICelera
Cytogenetic Map9F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14681479   PMID:16141072   PMID:16141073   PMID:21677750   PMID:27811987   PMID:31666509  


Genomics

Comparative Map Data
Slc22a14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,998,521 - 119,019,496 (-)NCBIGRCm39mm39
GRCm389119,169,453 - 119,190,430 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,169,455 - 119,365,553 (-)EnsemblGRCm38mm10GRCm38
MGSCv379119,078,574 - 119,099,511 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,018,154 - 119,039,091 (-)NCBImm8
Celera9119,637,344 - 119,658,281 (-)NCBICelera
Cytogenetic Map9F3NCBI
SLC22A14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl338,282,294 - 38,318,575 (+)EnsemblGRCh38hg38GRCh38
GRCh38338,281,662 - 38,318,575 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37338,323,785 - 38,360,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,322,449 - 38,334,863 (+)NCBINCBI36hg18NCBI36
Build 34338,322,430 - 38,335,069NCBI
Celera338,283,102 - 38,295,539 (+)NCBI
Cytogenetic Map3p22.2NCBI
HuRef338,389,428 - 38,401,865 (+)NCBIHuRef
CHM1_1338,275,465 - 38,311,760 (+)NCBICHM1_1
Slc22a14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08127,858,425 - 127,871,192 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08127,065,929 - 127,078,390 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,132,131 - 124,145,289 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,153,605 - 124,167,928 (-)NCBI
Celera8118,069,008 - 118,081,349 (-)NCBICelera
Cytogenetic Map8q32NCBI
Slc22a14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554215,009,279 - 5,020,221 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554215,009,560 - 5,023,833 (-)NCBIChiLan1.0ChiLan1.0
SLC22A14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1338,463,156 - 38,499,098 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,486,595 - 38,498,833 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0338,179,107 - 38,216,934 (+)NCBIMhudiblu_PPA_v0panPan3
SLC22A14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl238,075,539 - 8,101,828 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1238,075,485 - 8,104,214 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc22a14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647327,487,459 - 27,501,226 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC22A14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1323,149,231 - 23,159,598 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11323,148,924 - 23,162,263 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,363,455 - 25,399,166 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC22A14
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl151,098,235 - 1,110,868 (-)Ensembl
ChlSab1.1151,097,989 - 1,111,253 (-)NCBI
Slc22a14
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477319,964,690 - 19,980,122 (+)NCBI

Position Markers
Slc22a14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F3UniSTS
cM Map971.33UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:597
Count of miRNA genes:289
Interacting mature miRNAs:317
Transcripts:ENSMUST00000093775, ENSMUST00000127794, ENSMUST00000152061, ENSMUST00000170400
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000093775   ⟹   ENSMUSP00000091289
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,169,455 - 119,190,407 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127794   ⟹   ENSMUSP00000120144
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,180,966 - 119,190,362 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152061   ⟹   ENSMUSP00000117967
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,169,668 - 119,173,652 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170400   ⟹   ENSMUSP00000131982
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,169,456 - 119,365,553 (-)Ensembl
RefSeq Acc Id: NM_001037749   ⟹   NP_001032838
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,998,524 - 119,019,461 (-)NCBI
GRCm389119,169,456 - 119,190,395 (-)NCBI
MGSCv379119,078,574 - 119,099,511 (-)RGD
Celera9119,637,344 - 119,658,281 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011242980   ⟹   XP_011241282
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,998,521 - 119,019,432 (-)NCBI
GRCm389119,169,453 - 119,190,366 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242981   ⟹   XP_011241283
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,998,521 - 119,019,496 (-)NCBI
GRCm389119,169,453 - 119,190,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242982   ⟹   XP_011241284
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,998,521 - 119,019,418 (-)NCBI
GRCm389119,169,453 - 119,190,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242983   ⟹   XP_011241285
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,998,521 - 119,019,418 (-)NCBI
GRCm389119,169,453 - 119,190,352 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001032838   ⟸   NM_001037749
- UniProtKB: Q497L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241283   ⟸   XM_011242981
- Peptide Label: isoform X1
- UniProtKB: Q497L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241285   ⟸   XM_011242983
- Peptide Label: isoform X1
- UniProtKB: Q497L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241282   ⟸   XM_011242980
- Peptide Label: isoform X1
- UniProtKB: Q497L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241284   ⟸   XM_011242982
- Peptide Label: isoform X1
- UniProtKB: Q497L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000131982   ⟸   ENSMUST00000170400
RefSeq Acc Id: ENSMUSP00000120144   ⟸   ENSMUST00000127794
RefSeq Acc Id: ENSMUSP00000091289   ⟸   ENSMUST00000093775
RefSeq Acc Id: ENSMUSP00000117967   ⟸   ENSMUST00000152061
Protein Domains
MFS

Promoters
RGD ID:6845158
Promoter ID:MM_KWN:59121
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000068011,   OTTMUST00000068012
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369119,100,021 - 119,100,521 (-)MPROMDB
RGD ID:8671180
Promoter ID:EPDNEW_M13621
Type:initiation region
Name:Slc22a14_1
Description:Mus musculus solute carrier family 22 , member 14 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389119,190,395 - 119,190,455EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685974 AgrOrtholog
Ensembl Genes ENSMUSG00000070280 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000091289 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000117967 UniProtKB/TrEMBL
  ENSMUSP00000120144 UniProtKB/TrEMBL
  ENSMUSP00000131982 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000093775 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000127794 UniProtKB/TrEMBL
  ENSMUST00000152061 UniProtKB/TrEMBL
  ENSMUST00000170400 UniProtKB/TrEMBL
InterPro MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  Sub_transporter UniProtKB/TrEMBL
KEGG Report mmu:382113 UniProtKB/TrEMBL
MGD MGI:2685974 ENTREZGENE
NCBI Gene 382113 ENTREZGENE
Pfam Sugar_tr UniProtKB/TrEMBL
PhenoGen Slc22a14 PhenoGen
PROSITE MFS UniProtKB/TrEMBL
Superfamily-SCOP MFS_gen_substrate_transporter UniProtKB/TrEMBL
UniGene Mm.335525 ENTREZGENE
UniProt D3YUH1_MOUSE UniProtKB/TrEMBL
  F7AMC9_MOUSE UniProtKB/TrEMBL
  Q497L9 ENTREZGENE, UniProtKB/TrEMBL