Gm5458 (predicted gene 5458) - Rat Genome Database

Name: Gm5458
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Gm5458 (predicted gene 5458) Mus musculus

Analyze

No known orthologs.

Symbol:

Gm5458

Name:

predicted gene 5458

RGD ID:

1613943

MGI Page

MGI

Description:

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

alpha takusan-like; EG432825

RGD Orthologs

Alliance Genes

More Info

homologs ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Alliance orthologs ³				less info ...
Rattus norvegicus (Norway rat):	MGC116197 (similar to RIKEN cDNA 1700001E04)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Spetex2l1 (Spetex-2 protein like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Girdinl1 (girders of actin filaments like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Spetex2l2 (Spetex-2 protein like 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	19,644,206 - 19,652,655 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	19,644,207 - 19,652,649 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	19,594,138 - 19,602,587 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	19,594,139 - 19,602,581 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	20,413,360 - 20,421,809 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	18,384,834 - 18,393,283 (-)	NCBI		MGSCv36	mm8
Cytogenetic Map	14	A3	NCBI
cM Map	14	10.16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Cellular Component

cellular_component (ND)

Molecular Function

molecular_function (ND)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17610818

Genomics

Variants

Variants in Gm5458
267 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	314
Count of miRNA genes:	212
Interacting mature miRNAs:	221
Transcripts:	ENSMUST00000096121, ENSMUST00000163800
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10412071	Ssen3_m	suseptibility to Sendai virus 3 (mouse)			Not determined		14	1	26987934	Mouse
11532711	Sluc40_m	susceptibility to lung cancer 40 (mouse)					14	1	27379943	Mouse
1301991	Wta3_m	weight adult 3 (mouse)			Not determined		14	3887473	37887650	Mouse
4141550	Dbm3_m	diabetes modifier 3 (mouse)			Not determined			5143473	39143596	Mouse
4141265	Appd2_m	APP associated premature death 2 (mouse)			Not determined		14	5945552	30114862	Mouse
4141864	Mrdq4_m	modifier of retinal degeneration QTL 4 (mouse)			Not determined			9923245	48765082	Mouse
1300779	Dyscalc4_m	dystrophic cardiac calcinosis 4 (mouse)			Not determined		14	12212871	46213007	Mouse
27226748	Femd8_m	femur midshaft diameter 8, 10 week (mouse)					14	13769273	46737457	Mouse
27226752	Femd4_m	femur midshaft diameter 4, 5 week (mouse)					14	13769273	47237457	Mouse
1300544	Hypn_m	hyperinsulinemia (mouse)			Not determined		14	15160616	49160765	Mouse
1301372	Sluc13_m	susceptibility to lung cancer 13 (mouse)			Not determined		14	18827604	52827726	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001403651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_030247878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC174797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC060995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000096121 ⟹ ENSMUSP00000093833

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	19,644,207 - 19,652,649 (-)	Ensembl
GRCm38.p6 Ensembl	14	19,594,139 - 19,602,581 (-)	Ensembl

RefSeq Acc Id:

NM_001024706 ⟹ NP_001019877

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	19,644,206 - 19,652,655 (-)	NCBI
GRCm38	14	19,594,138 - 19,602,587 (-)	NCBI
MGSCv37	14	20,413,360 - 20,421,809 (-)	RGD
cM Map	14		ENTREZGENE

Sequence:

show sequence

ACCTGTGTTGTGGTGACAGCAACTGCCTGTGGTTCATCACTTCTGTTTGCTCTGGGATCACCAG
CAGGAATGTTTTCCTGGCTGCTCAGGCTATGTCAGAAAGAGAATGGCGATGAAGGAGACACCAG
ACCAACAAAGAAGGAAGAGGGAATCCTTTCTCATGAAAAAGGAAGAAGGAAATCATTCTGGAGA
AGGCACAGGTCTGCTAGAAATACTTCAACCCAAAATTCCAACATCACTAATCAGATATCAAATA
TAAATAAAGTTAGAGAATTGAAATTGGATATGAGGAAGATCAGCAATGACATGGAGGAAATGTG
TGGAATCCTGAACCTTTACATGTATGAGGATTTGAACTACAGGATGAACACTGAATTCAACATC
ATTAAATCACAACATGAGAAGACAATGTTGGATATGGATAAAATGACCCAGTCCATAATTGCTT
CCATGAAGTTCTCCGAGGAACTGTTAAAAGATAACTATTCCTACAGCATCAAGCAGAAACACCG
CCTCCGTGAGTGCACTCAACTAAAGGAAAAAGTGAGGATATTACTGAATGAGAACAGAAAGGTG
CTGGTGGAGCAGGCTGGAATGCAAGTGTCCCGTGGGGAAGAAAAGAGGTTCTGTGAGGAGGCCA
GCAAGAACATGTGTGTCTCAAGTGCCAAGGAGCAGCAGGTGTGATCATGAAATCCCACAGATAT
CAGACCCAGATGGATCTCTGCATTCTTCATGGGACCTGGGCTCCATAGTTTCTTCAGAGCCAGA
CTGAATTACAAAGTCCATCATAAATTCATTGTGGAGAGTGTGTCCAACTCTCTGGATAGGAACT
TAATGTTGGAAAACTTACCCATGCTGCATCCTTGTTGTCAAATATTTAGCTACTGTGAAAATTC
TGTGGATGATGATGTTGAACACATTAATGTCAAATACATCAGTATTTCTGTAATAACTCTCATT
AATTAAAAGCATAGTCTAAGGGAATAAAAAGCTGTCAGAAAACA

hide sequence

RefSeq Acc Id:

NM_001403651 ⟹ NP_001390580

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	19,644,206 - 19,652,655 (-)	NCBI

RefSeq Acc Id:

XM_030247878 ⟹ XP_030103738

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	19,644,206 - 19,652,649 (-)	NCBI
GRCm38	14	19,594,138 - 19,602,581 (-)	NCBI

Sequence:

show sequence

GTTGTGGTGACAGCAACTGCCTGTGGTTCATCACTTCTGTTTGCTCTGGGATCACCAGCAGGAA
TGTTTTCCTGGCTGCTCAGGCTATGTCAGAAAGAGAATGGCGATGAAGGAGACACCAGACCAAC
AAAGAAGGAAGAGGGAATCCTTTCTCATGAAAAAGGAAGAAGGAAATCATTCTGGAGAAGGCAC
AGGTCTGCTAGAAATACTTCAACCCAAAATTCCAACATCACTAATCAGATATCAAATATAAATA
AAGTTAGAGAATTGAAATTGGATATGAGGAAGATCAGCAATGACATGGAGGAAATGTGTGGAAT
CCTGAACCTTTACATGTATGAGGATTTGAACTACAGGATGAACACTGAATTCAACATCATTAAA
TCACAACATGAGAAGACAATGTTGGATATGGATAAAATGACCCAGTCCATAATTGCTTCCATGA
AGTTCTCCGAGGAACTGTTAAAAGATAACTATTCCTACAGCATCAAGCAGAAAAGAGGTTCTGT
GAGGAGGCCAGCAAGAACATGTGTGTCTCAAGTGCCAAGGAGCAGCAGGTGTGATCATGAAATC
CCACAGATATCAGACCCAGATGGATCTCTGCATTCTTCATGGGACCTGGGCTCCATAGTTTCTT
CAGAGCCAGACTGAATTACAAAGTCCATCATAAATTCATTGTGGAGAGTGTGTCCAACTCTCTG
GATAGGAACTTAATGTTGGAAAACTTACCCATGCTGCATCCTTGTTGTCAAATATTTAGCTACT
GTGAAAATTCTGTGGATGATGATGTTGAACACATTAATGTCAAATACATCAGTATTTCTGTAAT
AACTCTCATTAATTAAAAGCATAGTCTAAGGGAATAAAAAGCTGTCAGAAAACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001019877	(Get FASTA)	NCBI Sequence Viewer
	NP_001390580	(Get FASTA)	NCBI Sequence Viewer
	XP_030103738	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH60995	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000093833
	ENSMUSP00000093833.6

RefSeq Acc Id:	NP_001019877 ⟸ NM_001024706
- Peptide Label:	isoform 1
- UniProtKB:	L7N219 (UniProtKB/TrEMBL), K7N6Y0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFSWLLRLCQKENGDEGDTRPTKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNIN KVRELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMDKMTQSIIASM KFSEELLKDNYSYSIKQKHRLRECTQLKEKVRILLNENRKVLVEQAGMQVSRGEEKRFCEEASK NMCVSSAKEQQV hide sequence

RefSeq Acc Id:	XP_030103738 ⟸ XM_030247878
- Peptide Label:	isoform X2
- UniProtKB:	Q6P8Z5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSMUSP00000093833 ⟸ ENSMUST00000096121

RefSeq Acc Id:	NP_001390580 ⟸ NM_001403651
- Peptide Label:	isoform 2

Protein Domains

Disks large homolog 5 N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-L7N219-F1-model_v2	AlphaFold	L7N219	1-204	view protein structure

Promoters

RGD ID:

8681570

Promoter ID:

EPDNEW_M18816

Type:

initiation region

Name:

Gm5458_1

Description:

Mus musculus predicted gene 5458 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	14	19,602,587 - 19,602,647	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3646663	AgrOrtholog
Ensembl Genes	ENSMUSG00000095024	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000096121	ENTREZGENE
	ENSMUST00000096121.12	UniProtKB/TrEMBL
InterPro	DUF622	UniProtKB/TrEMBL
KEGG Report	mmu:432825	UniProtKB/TrEMBL
MGD	MGI:3646663	ENTREZGENE
NCBI Gene	432825	ENTREZGENE
PANTHER	2610042L04RIK PROTEIN-RELATED	UniProtKB/TrEMBL
	SPEER/SPETEX	UniProtKB/TrEMBL
Pfam	Takusan	UniProtKB/TrEMBL
PhenoGen	Gm5458	PhenoGen
UniProt	K7N6Y0	ENTREZGENE
	L7N219	ENTREZGENE, UniProtKB/TrEMBL
	Q6P8Z5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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