Gcnt4 (glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)) - Rat Genome Database

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Gene: Gcnt4 (glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)) Mus musculus
Analyze
Symbol: Gcnt4
Name: glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
RGD ID: 1613284
MGI Page MGI
Description: Predicted to enable acetylglucosaminyltransferase activity. Acts upstream of or within several processes, including inter-male aggressive behavior; neutrophil homeostasis; and thyroid hormone metabolic process. Predicted to be located in Golgi apparatus and membrane. Orthologous to human GCNT4 (glucosaminyl (N-acetyl) transferase 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4; C2GNT; C2gnt3; core 2 beta-1,6-N-acetylglucosaminyltransferase 3; core 2-branching enzyme 3; core2-GlcNAc-transferase 3; glucosaminyl (N-acetyl) transferase 3, mucin type pseudogene; glucosaminyl transferase 4, core 2; Gm279; Gm73
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,060,852 - 97,087,422 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1397,061,197 - 97,087,414 (+)EnsemblGRCm39 Ensembl
GRCm381396,924,344 - 96,950,914 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1396,924,689 - 96,950,906 (+)EnsemblGRCm38mm10GRCm38
MGSCv371397,694,644 - 97,720,869 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera13100,561,219 - 100,587,502 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14610273   PMID:16141072   PMID:16141073   PMID:19349303   PMID:20855471   PMID:21873635  
PMID:22736280   PMID:23408841   PMID:23555902   PMID:29091030   PMID:38180297  


Genomics

Comparative Map Data
Gcnt4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,060,852 - 97,087,422 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1397,061,197 - 97,087,414 (+)EnsemblGRCm39 Ensembl
GRCm381396,924,344 - 96,950,914 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1396,924,689 - 96,950,906 (+)EnsemblGRCm38mm10GRCm38
MGSCv371397,694,644 - 97,720,869 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera13100,561,219 - 100,587,502 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
GCNT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38575,016,969 - 75,054,060 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl575,025,346 - 75,052,558 (-)EnsemblGRCh38hg38GRCh38
GRCh37574,321,171 - 74,348,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,359,045 - 74,362,480 (-)NCBINCBI36Build 36hg18NCBI36
Celera570,217,451 - 70,220,886 (-)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef569,528,134 - 69,531,569 (-)NCBIHuRef
CHM1_1573,756,061 - 73,759,496 (-)NCBICHM1_1
T2T-CHM13v2.0575,497,819 - 75,535,608 (-)NCBIT2T-CHM13v2.0
Gcnt4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8229,987,944 - 30,017,708 (+)NCBIGRCr8
mRatBN7.2228,253,325 - 28,283,082 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,252,860 - 28,283,082 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx235,300,997 - 35,331,013 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0233,401,074 - 33,431,089 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0228,215,443 - 28,246,105 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0 Ensembl227,713,880 - 27,780,119 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0246,825,580 - 46,828,021 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,439,605 - 27,441,008 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera224,297,063 - 24,327,571 (+)NCBICelera
Cytogenetic Map2q12NCBI
Gcnt4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,662,036 - 25,681,948 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,661,648 - 25,681,948 (+)NCBIChiLan1.0ChiLan1.0
GCNT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2440,247,671 - 40,278,777 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1538,401,330 - 38,432,409 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0540,249,346 - 40,279,559 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1540,863,275 - 40,889,919 (+)NCBIpanpan1.1PanPan1.1panPan2
GCNT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1331,198,656 - 31,222,523 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl331,217,562 - 31,218,926 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha332,432,498 - 32,441,223 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0331,129,485 - 31,153,307 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1331,059,370 - 31,083,226 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0331,030,795 - 31,054,614 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0331,408,140 - 31,431,040 (+)NCBIUU_Cfam_GSD_1.0
Gcnt4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213189,211,120 - 189,234,616 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365491,645,256 - 1,647,307 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GCNT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl284,105,655 - 84,134,721 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1284,105,652 - 84,135,122 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,693,080 - 85,722,498 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GCNT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,392,170 - 69,421,082 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl469,393,958 - 69,395,319 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604918,168,983 - 18,198,423 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gcnt4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462495115,367 - 38,669 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gcnt4
1124 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1010
Count of miRNA genes:615
Interacting mature miRNAs:723
Transcripts:ENSMUST00000171324
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1370111284104111284Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined76132600112431103Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1378036508112036508Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1479239045113239162Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379239045113239162Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382739968116740106Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383876060117876256Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386148119120461536Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386341617120341758Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87901985112431103Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391383692120883175Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391965303120883175Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393875267120883175Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394528399120883175Mouse
1558763Gct9_mgranulosa cell tumorigenesis 9 (mouse)Not determined1395036824120883175Mouse
1357468Rplag_mreduced platelet aggregation (mouse)Not determined1395502130120883175Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000171324   ⟹   ENSMUSP00000130496
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1397,061,197 - 97,087,414 (+)Ensembl
GRCm38.p6 Ensembl1396,924,689 - 96,950,906 (+)Ensembl
RefSeq Acc Id: NM_001166065   ⟹   NP_001159537
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,061,221 - 97,087,422 (+)NCBI
GRCm381396,924,713 - 96,950,914 (+)NCBI
MGSCv371397,694,644 - 97,720,869 (+)RGD
Celera13100,561,219 - 100,587,502 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001376999   ⟹   NP_001363928
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,060,852 - 97,087,422 (+)NCBI
GRCm381396,924,344 - 96,950,914 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517596   ⟹   XP_006517659
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,061,139 - 97,087,422 (+)NCBI
GRCm381396,924,630 - 96,950,914 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517597   ⟹   XP_006517660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,061,139 - 97,087,422 (+)NCBI
GRCm381396,925,194 - 96,950,914 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517598   ⟹   XP_006517661
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,061,139 - 97,087,422 (+)NCBI
GRCm381396,924,955 - 96,950,914 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517600   ⟹   XP_006517663
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,061,702 - 97,087,422 (+)NCBI
GRCm381396,925,194 - 96,950,914 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517601   ⟹   XP_006517664
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,062,071 - 97,087,422 (+)NCBI
GRCm381396,925,560 - 96,950,914 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001159537   ⟸   NM_001166065
- UniProtKB: E9Q649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517659   ⟸   XM_006517596
- Peptide Label: isoform X1
- UniProtKB: E9Q649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517661   ⟸   XM_006517598
- Peptide Label: isoform X1
- UniProtKB: E9Q649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517660   ⟸   XM_006517597
- Peptide Label: isoform X1
- UniProtKB: E9Q649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517663   ⟸   XM_006517600
- Peptide Label: isoform X1
- UniProtKB: E9Q649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517664   ⟸   XM_006517601
- Peptide Label: isoform X1
- UniProtKB: E9Q649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001363928   ⟸   NM_001376999
- UniProtKB: E9Q649 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000130496   ⟸   ENSMUST00000171324

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9Q649-F1-model_v2 AlphaFold E9Q649 1-455 view protein structure

Promoters
RGD ID:8681078
Promoter ID:EPDNEW_M18570
Type:initiation region
Name:Gcnt4_1
Description:Mus musculus glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase), mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381396,924,713 - 96,924,773EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2684919 AgrOrtholog
Ensembl Genes ENSMUSG00000091387 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000171324 ENTREZGENE
  ENSMUST00000171324.3 UniProtKB/Swiss-Prot
InterPro Glyco_trans_14 UniProtKB/Swiss-Prot
KEGG Report mmu:218476 UniProtKB/Swiss-Prot
MGD MGI:2684919 ENTREZGENE
NCBI Gene 218476 ENTREZGENE
PANTHER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 UniProtKB/Swiss-Prot
  GLYCOSYLTRANSFERASE 14 FAMILY MEMBER UniProtKB/Swiss-Prot
Pfam Branch UniProtKB/Swiss-Prot
PhenoGen Gcnt4 PhenoGen
UniProt E9Q649 ENTREZGENE, UniProtKB/Swiss-Prot