Prrt2 (proline-rich transmembrane protein 2)

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Gene: Prrt2 (proline-rich transmembrane protein 2) Mus musculus

Analyze

Symbol:

Prrt2

Name:

proline-rich transmembrane protein 2

RGD ID:

1613176

MGI Page

MGI

Description:

Exhibits syntaxin-1 binding activity. Involved in negative regulation of SNARE complex assembly; negative regulation of short-term synaptic potentiation; and synaptic vesicle exocytosis. Localizes to several cellular components, including glutamatergic synapse; integral component of presynaptic membrane; and synaptic vesicle. Is expressed in brain. Used to study episodic kinesigenic dyskinesia 1. Human ortholog(s) of this gene implicated in benign familial neonatal epilepsy and episodic kinesigenic dyskinesia 1. Orthologous to human PRRT2 (proline rich transmembrane protein 2); INTERACTS WITH 3,4-methylenedioxymethamphetamine; benzo[a]pyrene; ethanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

1500031I19Rik; AI195361; dispanin subfamily B member 3; DSPB3

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	126,616,707 - 126,620,800 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	126,616,703 - 126,620,383 (-)	Ensembl
GRCm38	7	127,017,542 - 127,021,450 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	127,017,531 - 127,021,211 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	134,161,056 - 134,164,725 (-)	NCBI	GRCm37		mm9	NCBIm37
Celera	7	126,865,670 - 126,869,339 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

16p11.2 Deletion Syndrome (ISO)

autism spectrum disorder (ISO)

autistic disorder (ISO)

benign familial infantile epilepsy (ISS)

Benign Familial Infantile Seizures, 2 (ISO)

Developmental Disabilities (ISO)

epilepsy (ISO)

episodic kinesigenic dyskinesia 1 (IEA,ISO)

Familial Infantile Convulsions and Paroxysmal Choreoathetosis (ISO)

Febrile Seizures (ISO)

intellectual disability (ISO)

Neurodevelopmental Disorders (ISO)

paroxysmal nonkinesigenic dyskinesia 1 (ISO)

schizophrenia (ISO)

Spondylocostal Dysostosis 5 (ISO)

visual epilepsy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

3,4-methylenedioxymethamphetamine (EXP)

6-propyl-2-thiouracil (ISO)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

amphetamine (ISO)

antirheumatic drug (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (ISO)

C60 fullerene (ISO)

cisplatin (ISO)

dorsomorphin (ISO)

endosulfan (ISO)

ethanol (EXP)

hydrogen peroxide (ISO)

PCB138 (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

trichostatin A (ISO)

triptonide (EXP)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium-dependent activation of synaptic vesicle fusion (IDA,IMP,IPI)

negative regulation of short-term synaptic potentiation (IMP)

negative regulation of SNARE complex assembly (IMP)

neuromuscular process controlling posture (ISO)

synaptic vesicle fusion to presynaptic active zone membrane (IMP)

Cellular Component

axon terminus (IDA)

cell junction (IEA)

cell projection (IEA)

cytoplasmic vesicle (IEA)

glutamatergic synapse (IDA,IMP,IPI)

integral component of membrane (IEA)

integral component of presynaptic membrane (IDA,IEP,IMP)

membrane (IBA,IDA)

neuron projection (ISO)

plasma membrane (IDA,ISO)

postsynaptic membrane (IEA)

presynapse (IDA)

presynaptic membrane (IDA)

synapse (IEA)

synaptic vesicle (IDA)

vesicle (IDA)

Molecular Function

protein binding (IPI)

SH3 domain binding (ISO)

syntaxin-1 binding (IDA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal contextual conditioning behavior (IEA)

abnormal cued conditioning behavior (IEA)

abnormal excitatory postsynaptic currents (IAGP)

abnormal excitatory synapse morphology (IAGP)

abnormal freezing behavior (IEA)

abnormal inhibitory postsynaptic currents (IAGP)

abnormal inhibitory synapse morphology (IAGP)

abnormal miniature excitatory postsynaptic currents (IAGP)

abnormal motor capabilities/coordination/movement (IAGP)

abnormal synapse morphology (IAGP)

abnormal synaptic plasticity (IAGP)

audiogenic seizures (IAGP)

decreased body weight (IAGP)

decreased circulating alkaline phosphatase level (IEA)

decreased excitatory postsynaptic current amplitude (IAGP)

decreased startle reflex (IEA)

dystonia (IAGP)

hyperactivity (IAGP)

impaired balance (IAGP)

impaired coordination (IAGP)

impaired righting response (IAGP)

increased grooming behavior (IAGP)

increased susceptibility to pharmacologically induced seizures (IAGP)

induced hyperactivity (IAGP)

jerky movement (IAGP)

jumpy (IAGP)

retropulsion (IAGP)

short tibia (IEA)

thin cerebral cortex (IAGP)

References

References - curated


1.	OMIM Disease Annotation Pipeline
2.	RGD automated import pipeline
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:16141072	PMID:16141073	PMID:18799693	PMID:21677750	PMID:21873635	PMID:22101681
PMID:22363774	PMID:22832103	PMID:26797119	PMID:27052163	PMID:27172900	PMID:28007585	PMID:29056747	PMID:29111324	PMID:29554219	PMID:29912316	PMID:30884140	PMID:32325033
PMID:32891704

Genomics

Comparative Map Data

Prrt2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	126,616,707 - 126,620,800 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	126,616,703 - 126,620,383 (-)	Ensembl
GRCm38	7	127,017,542 - 127,021,450 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	127,017,531 - 127,021,211 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	134,161,056 - 134,164,725 (-)	NCBI	GRCm37		mm9	NCBIm37
Celera	7	126,865,670 - 126,869,339 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI

PRRT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	16	29,811,382 - 29,815,892 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	16	29,812,193 - 29,815,920 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	16	29,823,514 - 29,827,202 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	29,730,910 - 29,734,703 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	16	72,969,059 - 72,972,852 (-)	NCBI
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	27,484,047 - 27,487,840 (+)	NCBI		HuRef
CHM1_1	16	31,039,218 - 31,043,011 (+)	NCBI		CHM1_1

Prrt2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	181,625,243 - 181,628,905 (-)	NCBI
Rnor_6.0 Ensembl	1	198,451,324 - 198,454,914 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	198,451,042 - 198,454,998 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	205,431,478 - 205,435,409 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	186,196,585 - 186,199,258 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	1	179,279,909 - 179,283,499 (-)	NCBI		Celera
Cytogenetic Map	1	q37	NCBI

Prrt2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955493	7,144,389 - 7,148,613 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRRT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	16	30,182,381 - 30,186,015 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	30,183,352 - 30,187,862 (+)	Ensembl	panpan1.1		panPan2

PRRT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	17,872,670 - 17,877,502 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	17,873,521 - 17,903,184 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	19,449,454 - 19,454,305 (+)	NCBI
ROS_Cfam_1.0	6	18,006,274 - 18,011,127 (+)	NCBI
UMICH_Zoey_3.1	6	17,805,776 - 17,810,626 (+)	NCBI
UNSW_CanFamBas_1.0	6	17,721,471 - 17,726,322 (+)	NCBI
UU_Cfam_GSD_1.0	6	18,036,767 - 18,041,616 (+)	NCBI

Prrt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	124,562,323 - 124,565,929 (-)	NCBI
SpeTri2.0	NW_004936501	12,660,181 - 12,663,788 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRRT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	18,048,614 - 18,052,481 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	18,534,378 - 18,543,204 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRRT2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	26,838,280 - 26,841,918 (-)	NCBI
ChlSab1.1 Ensembl	5	26,839,454 - 26,841,916 (-)	Ensembl

Prrt2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624782	13,390,347 - 13,393,775 (-)	NCBI

Position Markers

RH135947

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	7	127,017,350 - 127,017,543	UniSTS	GRCm38
MGSCv37	7	134,160,864 - 134,161,057	UniSTS	GRCm37
Celera	7	126,865,478 - 126,865,671	UniSTS
Cytogenetic Map	7	F4	UniSTS
Cytogenetic Map	7	F3	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25314307	Mlh1fc2_m	MLH1 foci count 2 (mouse)					7	6500000	133900000	Mouse
1301158	Eae4_m	susceptibility to experimental allergic encephalomyelitis 4 (mouse)			Not determined		7	19413473	142366067	Mouse
27226751	Femd5_m	femur midshaft diameter 5, 10 week (mouse)					7	53600000	143600000	Mouse
27226778	Femd11_m	femur midshaft diameter 11, 16 week (mouse)					7	57300000	134400000	Mouse
27095933	Ulnl3_m	ulna length 3, 5 week (mouse)					7	73500000	143600000	Mouse
26884398	Humsd6_m	humerus midshaft diameter 6, 16 week (mouse)					7	79000000	137300000	Mouse
27095930	Ulnl10_m	ulna length 10, 16 week (mouse)					7	81200000	127100000	Mouse
1300528	Ssial3_m	susceptibility to sialadenitis 3 (mouse)			Not determined		7	93792641	127792834	Mouse
1301478	Eae26_m	susceptibility to experimental allergic encephalomyelitis 26 (mouse)			Not determined		7	98565687	132565775	Mouse
13524850	Asrq7_m	acoustic startle response 7 (mouse)					7	98795739	132795739	Mouse
10412104	Tons2_m	tongue size 2 (mouse)			Not determined		7	100238481	134238481	Mouse
11039524	Tbbr3_m	Trypanosoma brucei brucei response 3 (mouse)					7	101151499	135151620	Mouse
1301447	Fembm3_m	femoral bone morphometry 3 (mouse)			Not determined		7	101394038	135394119	Mouse
1357460	Vtbt4_m	vertebral trabecular bone trait 4 (mouse)			Not determined		7	102094158	136094307	Mouse
1301105	Cfld4_m	cystic fibrosis lung disease 4 (mouse)			Not determined		7	102094158	136094307	Mouse
1300721	Cfbw3_m	cystic fibrosis body weight 3 (mouse)			Not determined		7	102094158	136094307	Mouse
4142312	Nilac4_m	nicotine induced locomotor activity 4 (mouse)			Not determined		7	102885996	136886157	Mouse
5491192	Mobq1_m	multigenic obesity QTL 1 (mouse)			Not determined		7	105651440	139651588	Mouse
13524852	Asrq7a_m	acoustic startle response 7a (mouse)					7	105750785	139750785	Mouse
14700684	Civq1_m	cerebral infarct volume QTL 1 (mouse)					7	110108163	144108163	Mouse
14700687	Civq5_m	cerebral infarct volume QTL 5 (mouse)					7	110108163	144108163	Mouse
14700688	Civq6_m	cerebral infarct volume QTL 6 (mouse)					7	110108163	144108163	Mouse
10402499	Lmr21_m	leishmaniasis resistance 21 (mouse)			Not determined		7	111365511	145365612	Mouse
11059562	Lmr21b_m	leishmaniasis resistance 21b (mouse)					7	111365511	145365612	Mouse
1301898	Alcp14_m	alcohol preference locus 14 (mouse)			Not determined		7	111564398	145441459	Mouse
1302032	Alcp12_m	alcohol preference locus 12 (mouse)			Not determined		7	111564398	145441459	Mouse
1300670	Sluc19_m	susceptibility to lung cancer 19 (mouse)			Not determined		7	111564398	145441459	Mouse
4142444	Femwf5_m	femur work to failure 5 (mouse)			Not determined			112950524	145441459	Mouse
1300747	Skts2_m	skin tumor susceptibility 2 (mouse)			Not determined		7	113321003	145441459	Mouse
38501072	Stsl7_m	Salmonella typhimurium susceptibility locus 7 (mouse)					7	116100000	128900000	Mouse
1300677	Bmd9_m	bone mineral density 9 (mouse)			Not determined		7	117032360	145441459	Mouse
15092059	Wogrme1_m	week one growth rate, maternal effect 1 (mouse)					7	117600000	134500000	Mouse
11059561	Lmr21a_m	leishmaniasis resistance 21a (mouse)					7	118151499	128365612	Mouse
1357711	Adbg1_m	adult body growth 1 (mouse)			Not determined		7	119094158	144844577	Mouse
1301773	Stheal7_m	soft tissue heal 7 (mouse)			Not determined		7	119530844	145441459	Mouse
38501070	Tip5_m	tuberculosis immunophenotype 5, IFN-g level (mouse)					7	121000000	130700000	Mouse
1357613	Bsbob2_m	BSB obesity 2 (mouse)			Not determined		7	122651440	129217600	Mouse
1301903	Tlsm1_m	thymic lymphoma susceptible 1 (mouse)			Not determined		7	122651440	135569172	Mouse
38501066	Tip2_m	tuberculosis immunophenotype 2, spleen CFU (mouse)					7	124700000	127300000	Mouse
4141945	Il4ppq_m	IL-4 producing potential QTL (mouse)			Not determined		7	124914439	129217600	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1006
Count of miRNA genes:	569
Interacting mature miRNAs:	662
Transcripts:	ENSMUST00000159916, ENSMUST00000160767, ENSMUST00000161728, ENSMUST00000161931
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001102563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_036153413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_036153414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_036153415	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_004934182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK158895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB872849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB873187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC053419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF323287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB246480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000159916 ⟹ ENSMUSP00000124520

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	7	127,017,531 - 127,021,211 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000160767

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	7	127,017,543 - 127,020,974 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000161931 ⟹ ENSMUSP00000143833

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	7	127,018,158 - 127,019,595 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000201686 ⟹ ENSMUSP00000144451

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	7	127,017,648 - 127,019,902 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000201963

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	7	127,018,507 - 127,020,956 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000202045 ⟹ ENSMUSP00000144042

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	7	127,018,704 - 127,021,137 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000202936

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	7	127,019,395 - 127,020,355 (-)	Ensembl

RefSeq Acc Id:

NM_001102563 ⟹ NP_001096033

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	126,616,714 - 126,620,383 (-)	NCBI
GRCm38	7	127,017,542 - 127,021,211 (-)	NCBI
MGSCv37	7	134,161,056 - 134,164,725 (-)	RGD
Celera	7	126,865,670 - 126,869,339 (-)	RGD
cM Map	7		ENTREZGENE

Sequence:

show sequence

AGTGGAGCTTAGGGGAGGGGACCAGAGAAGAAGGGCCGAGCAAACCCGGAGGAGAGAGGAGGGG
AGACCCGCCACCTCCCTTCATTGCTCACAGACTTGTTCCCTCCCCGGTCTGCGGCTGCTGCAGC
AGCAGCGGCGGTGGCGGCGGGACGCAGGAGCAGTCCCGAGGCTGGCAGCGGATGAGACTGGGAC
CAACTGAGACTGCTGGATTTGCTACTGTCACTGTTGTCTCCTCTTCCCCACGGGCCCTCTCCCA
TCTCGCTTCTCTAAGATGGCAGCCAGCAGCTCTCAGGTCTCTGAGATGAAGGGGGTGGAAGACA
GTTCCAAAACCCAGACAGAAGGTCCCAGGCATTCTGAAGAAGGACTAGGTCCTGTCCAGGTTGT
AGCAGAGATCCCAGACCAGCCAGAGGCCCTTCAGCCGGGCCCAGGCATCACTGCAGCCCCTGTG
GACTCAGGGCCTAAGGCAGAGCTGGCACCAGAAACCACAGAGACCCCAGTTGAAACCCCAGAAA
CAGTCCAGGCCACAGACCTCAGTTTAAACCCAGAAGAAGGCTCCAAGGCCAGCCCCAGCCCCAG
CCCCAGCGAGGCACGCCAAGAGCCAGCATCCAAACCAGATGTGAACAGAGAGACTGCAGCAGAG
GAAGGGTCTGAGCCGCAGTCTACAGCCCCTCCTGAGCCAACCTCGGAGCCTGCTTTTCAGATAA
ACACCCAGTCAGACCCTCAGCCAACTTCCCAGCCTCCTCCTAAACCACCCCTTCAGGCAGAGCC
CCCCACCCAAGAGGACCCTACCACAGAGGTCCTGACAGAAAGTACAGGGGAAAAACAAGAAAAC
GGAGCAGTGGTTCCCCTTCAGGCTGGTGACGGGGAAGAGGGCCCAGCCCCCCAACCTCACTCAC
CACCCTCAACTAAAACACCCCCAGCCAATGGGGCTCCCCCCCGTGTGCTGCAGAAACTCGTTGA
GGAAGACAGAATAGGAAGGGCACACGGTGGGCATCCAGGATCTCCTCGAGGTAGCCTAAGCCGT
CATCCCAGCTCCCAGCTGGCAGGGCCTGGGGTGGAAGGGGGCGAAGGCACCCAGAAACCTCGGG
ACTATATCATCCTTGCCATCCTGTCCTGCTTCTGCCCCATGTGGCCTGTCAACATTGTGGCCTT
CGCTTATGCCGTCATGTCCCGGAACAGCCTGCAACAGGGGGACGTGGATGGGGCTCAACGTCTG
GGCCGAGTAGCCAAGCTCTTAAGCATCGTGGCGCTGGTTGGGGGGGTCCTCATCATCATCGCCT
CCTGCGTCATCAACTTAGGCGTGTATAAGTGAGGGGCTCTGCCCTGCATTCCAAGACTTTTCTT
CCTGTTGGGAGCTGTCTTGGGTCCATCCCTGTCCTGGGAGAATCCCAGTCCATGGCCCTGGCCC
CCATCTCTAGGGACCAAGGGAGCCTGAGCGGCCTTGTTTACAGCTTCTTTCCCCCTGCATCCTG
CCAGGCTCCTCTGCCAGCCATAGGCTTCCTTTCTCCCTGCACTTTTGCCTGCAGACCCCCACCC
CACTCCTGCCTCTTGACCTCCCTAACCCTGCACTCTGAAAACCTCTCTGCACTTCTGGAAGCCT
TCCTGAACATCTAAATTGTACTCTGCACCTCTGCATCTCTCCCAGCCTCCCTGCACTTCTTCCT
GCCTCTGGAATCCTCTGAACCTTATCCCTGGCCTCCCAACGTTCATTGTCTTGGTATCTAACCC
ATCCCGTTCTCCCCTTCCTTAACACCGTTTTTCCCCTTGCCACGTCCCCTGACCCTTTCTCCCT
TTTCATCTCCCCCTTAGCGTCTTCACCCTCCTGCCAACACTTAGTCTGCAAAAACTGCAGTACT
TAGGTCAGGCTGAGGGAAGAAGGATGGTGTGGGGAGAGGAGCCTAGCTGGGGGCTCTGACTGTT
CTCTACTGGGGACCACCCAGGCCCAGACCATACCCTACCCCTACCCCTAAGGTGCCTATTGGGT
CCCAAAGCTGGCAAGTGAGTCCTCACCTGGGGGACCTTCTGAGAGTCCTTATTCTGAACATCCA
GGGGAGGAAGGGGCATAGCTGCGCCTGAAGAGTCAGCCTGAATTGATCTGCCCGTTTGGGCTTT
TTAACCTCAGAGTTTCTTGTTTGAAGGTCTATTTATGTGCTTTGTAAACAGTAGAATTCAAAAC
AAAACAAACAAACAAAAACAGGACCAAAGTTCCCAGCTGCAGGGAGCAAGGGAAGGGTGGGGGA
GCTCTGTAATTATTCTCTAAGAGGATGAGGGAGGTTTGTTGCACGCGACAGCCCTCTGAGGAGG
CAGAGAGCCAGCTGCGATGCATTTCAGAGTTGGCGGGGTTTTTTGTTTGTTTCCTTTCTTTTTT
AAAAAAAAAAAAAAAAGTTGGGGGAAAACTAAAATTCCTTTTCAAAAAATAAAACTGAGTCTCC
CTTTTTGTATGCTGAATGCTGCATGAGTCTTAAACACTAATAAACAGAGAATGCATGAAAAAAA
AAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_036153413 ⟹ XP_036009306

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	126,616,707 - 126,620,800 (-)	NCBI

RefSeq Acc Id:

XM_036153414 ⟹ XP_036009307

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	126,616,707 - 126,620,786 (-)	NCBI

RefSeq Acc Id:

XM_036153415 ⟹ XP_036009308

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	126,616,707 - 126,620,531 (-)	NCBI

RefSeq Acc Id:

XR_004934182

RefSeq Status:

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	126,617,810 - 126,620,476 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001096033	(Get FASTA)	NCBI Sequence Viewer
	XP_036009306	(Get FASTA)	NCBI Sequence Viewer
	XP_036009307	(Get FASTA)	NCBI Sequence Viewer
	XP_036009308	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	E9PUL5	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001096033 ⟸ NM_001102563

- UniProtKB:

E9PUL5 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAASSSQVSEMKGVEDSSKTQTEGPRHSEEGLGPVQVVAEIPDQPEALQPGPGITAAPVDSGPK
AELAPETTETPVETPETVQATDLSLNPEEGSKASPSPSPSEARQEPASKPDVNRETAAEEGSEP
QSTAPPEPTSEPAFQINTQSDPQPTSQPPPKPPLQAEPPTQEDPTTEVLTESTGEKQENGAVVP
LQAGDGEEGPAPQPHSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQ
LAGPGVEGGEGTQKPRDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAK
LLSIVALVGGVLIIIASCVINLGVYK

hide sequence

RefSeq Acc Id:

ENSMUSP00000124520 ⟸ ENSMUST00000159916

RefSeq Acc Id:

ENSMUSP00000144042 ⟸ ENSMUST00000202045

RefSeq Acc Id:

ENSMUSP00000144451 ⟸ ENSMUST00000201686

RefSeq Acc Id:

ENSMUSP00000143833 ⟸ ENSMUST00000161931

RefSeq Acc Id:	XP_036009306 ⟸ XM_036153413
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_036009307 ⟸ XM_036153414
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_036009308 ⟸ XM_036153415
- Peptide Label:	isoform X1

Promoters

RGD ID:

8665625

Promoter ID:

EPDNEW_M10844

Type:

initiation region

Name:

Prrt2_1

Description:

Mus musculus proline-rich transmembrane protein 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	7	127,021,121 - 127,021,181	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1916267	AgrOrtholog
Ensembl Genes	ENSMUSG00000045114	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000124520	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000143833	UniProtKB/TrEMBL
	ENSMUSP00000144042	UniProtKB/TrEMBL
	ENSMUSP00000144451	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000159916	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000161931	UniProtKB/TrEMBL
	ENSMUST00000201686	UniProtKB/TrEMBL
	ENSMUST00000202045	UniProtKB/TrEMBL
InterPro	CD225/Dispanin_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:69017	UniProtKB/Swiss-Prot
MGD	MGI:1916267	ENTREZGENE
NCBI Gene	69017	ENTREZGENE
Pfam	CD225	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Prrt2	PhenoGen
UniProt	A0A0J9YTS8_MOUSE	UniProtKB/TrEMBL
	A0A0J9YU72_MOUSE	UniProtKB/TrEMBL
	A0A0J9YV24_MOUSE	UniProtKB/TrEMBL
	E9PUL5	ENTREZGENE, UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM