Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ptprh | Mouse | (+)-schisandrin B | multiple interactions | ISO | Ptprh (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PTPRH mRNA] | CTD | PMID:31150632 | Ptprh | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PTPRH mRNA | CTD | PMID:22206623 | Ptprh | Mouse | 17beta-estradiol | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Estradiol results in increased expression of PTPRH mRNA | CTD | PMID:20106945 and PMID:31614463 | Ptprh | Mouse | 17beta-estradiol | multiple interactions | ISO | PTPRH (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of PTPRH mRNA | CTD | PMID:30165855 | Ptprh | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTPRH mRNA | CTD | PMID:22298810 | Ptprh | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTPRH mRNA | CTD | PMID:21570461 | Ptprh | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTPRH mRNA | CTD | PMID:21632981 | Ptprh | Mouse | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:25768209 | Ptprh | Mouse | 4,4'-sulfonyldiphenol | decreases expression | ISO | PTPRH (Homo sapiens) | 6480464 | bisphenol S results in decreased expression of PTPRH mRNA | CTD | PMID:27685785 | Ptprh | Mouse | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of PTPRH mRNA | CTD | PMID:21346803 | Ptprh | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of PTPRH mRNA | CTD | PMID:24780913 | Ptprh | Mouse | acetamide | increases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | acetamide results in increased expression of PTPRH mRNA | CTD | PMID:31881176 | Ptprh | Mouse | acrylamide | affects expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Acrylamide affects the expression of PTPRH mRNA | CTD | PMID:28959563 | Ptprh | Mouse | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of PTPRH mRNA | CTD | PMID:35032568 | Ptprh | Mouse | aflatoxin B1 | decreases methylation | ISO | PTPRH (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PTPRH intron | CTD | PMID:30157460 | Ptprh | Mouse | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of PTPRH mRNA | CTD | PMID:37567420 | Ptprh | Mouse | all-trans-retinoic acid | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PTPRH mRNA | CTD | PMID:23724009 and PMID:23830798 | Ptprh | Mouse | ammonium chloride | affects expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of PTPRH mRNA | CTD | PMID:16483693 | Ptprh | Mouse | aristolochic acid A | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PTPRH mRNA | CTD | PMID:33212167 | Ptprh | Mouse | benzo[a]pyrene | affects methylation | ISO | PTPRH (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PTPRH exon | CTD | PMID:30157460 | Ptprh | Mouse | benzo[e]pyrene | decreases methylation | ISO | PTPRH (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of PTPRH exon | CTD | PMID:30157460 | Ptprh | Mouse | bisphenol A | increases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PTPRH mRNA | CTD | PMID:25181051 and PMID:32145629 | Ptprh | Mouse | bisphenol A | affects expression | ISO | PTPRH (Homo sapiens) | 6480464 | bisphenol A affects the expression of PTPRH mRNA | CTD | PMID:30903817 | Ptprh | Mouse | bisphenol A | decreases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PTPRH mRNA | CTD | PMID:30816183 and PMID:32528016 | Ptprh | Mouse | butanal | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of PTPRH mRNA | CTD | PMID:26079696 | Ptprh | Mouse | copper atom | multiple interactions | ISO | PTPRH (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PTPRH mRNA | CTD | PMID:20971185 | Ptprh | Mouse | copper(0) | multiple interactions | ISO | PTPRH (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PTPRH mRNA | CTD | PMID:20971185 | Ptprh | Mouse | copper(II) sulfate | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of PTPRH mRNA | CTD | PMID:19549813 | Ptprh | Mouse | Cuprizon | increases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of PTPRH mRNA | CTD | PMID:27523638 | Ptprh | Mouse | cyclosporin A | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PTPRH mRNA | CTD | PMID:20106945 more ... | Ptprh | Mouse | D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of PTPRH mRNA | CTD | PMID:37567420 | Ptprh | Mouse | dextran sulfate | decreases expression | EXP | | 6480464 | Dextran Sulfate results in decreased expression of PTPRH mRNA | CTD | PMID:37385329 | Ptprh | Mouse | doxorubicin | affects response to substance | ISO | PTPRH (Homo sapiens) | 6480464 | PTPRH mRNA affects the susceptibility to Doxorubicin | CTD | PMID:16044152 | Ptprh | Mouse | fructose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of PTPRH mRNA | CTD | PMID:37567420 | Ptprh | Mouse | glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of PTPRH mRNA | CTD | PMID:37567420 | Ptprh | Mouse | herbicide | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of PTPRH mRNA | CTD | PMID:37567420 | Ptprh | Mouse | ketamine | decreases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Ketamine results in decreased expression of PTPRH mRNA | CTD | PMID:20080153 | Ptprh | Mouse | leflunomide | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | leflunomide results in increased expression of PTPRH mRNA | CTD | PMID:28988120 | Ptprh | Mouse | methapyrilene | decreases methylation | ISO | PTPRH (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of PTPRH exon | CTD | PMID:30157460 | Ptprh | Mouse | mono(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of PTPRH mRNA | CTD | PMID:22401849 | Ptprh | Mouse | N-methyl-4-phenylpyridinium | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PTPRH mRNA | CTD | PMID:24810058 | Ptprh | Mouse | N-Nitrosopyrrolidine | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in increased expression of PTPRH mRNA | CTD | PMID:32234424 | Ptprh | Mouse | niclosamide | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Niclosamide results in increased expression of PTPRH mRNA | CTD | PMID:36318118 | Ptprh | Mouse | paraquat | decreases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of PTPRH mRNA | CTD | PMID:32680482 | Ptprh | Mouse | PCB138 | decreases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | Ptprh | Mouse | phenobarbital | affects expression | ISO | PTPRH (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PTPRH mRNA | CTD | PMID:19159669 | Ptprh | Mouse | quercetin | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Quercetin results in increased expression of PTPRH mRNA | CTD | PMID:21632981 | Ptprh | Mouse | raloxifene | affects expression | ISO | PTPRH (Homo sapiens) | 6480464 | Raloxifene Hydrochloride affects the expression of PTPRH mRNA | CTD | PMID:14699072 | Ptprh | Mouse | silicon dioxide | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PTPRH mRNA | CTD | PMID:25895662 | Ptprh | Mouse | sodium arsenite | decreases expression | ISO | PTPRH (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PTPRH mRNA | CTD | PMID:28595984 | Ptprh | Mouse | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of PTPRH mRNA | CTD | PMID:37682722 | Ptprh | Mouse | sodium arsenite | affects expression | ISO | PTPRH (Homo sapiens) | 6480464 | sodium arsenite affects the expression of PTPRH mRNA | CTD | PMID:34032870 | Ptprh | Mouse | sodium arsenite | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PTPRH mRNA | CTD | PMID:38568856 | Ptprh | Mouse | sunitinib | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PTPRH mRNA | CTD | PMID:31533062 | Ptprh | Mouse | tamoxifen | multiple interactions | ISO | PTPRH (Homo sapiens) | 6480464 | ESR2 protein affects the reaction [Tamoxifen results in decreased expression of PTPRH mRNA] | CTD | PMID:14699072 | Ptprh | Mouse | tamoxifen | affects expression | ISO | PTPRH (Homo sapiens) | 6480464 | Tamoxifen affects the expression of PTPRH mRNA | CTD | PMID:14699072 | Ptprh | Mouse | tetrachloromethane | decreases expression | ISO | Ptprh (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of PTPRH mRNA | CTD | PMID:31150632 | Ptprh | Mouse | tetrachloromethane | multiple interactions | ISO | Ptprh (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PTPRH mRNA] | CTD | PMID:31150632 | Ptprh | Mouse | thapsigargin | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of PTPRH mRNA | CTD | PMID:22378314 | Ptprh | Mouse | triclosan | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Triclosan results in increased expression of PTPRH mRNA | CTD | PMID:30510588 | Ptprh | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of PTPRH mRNA | CTD | PMID:33045310 | Ptprh | Mouse | tunicamycin | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of PTPRH mRNA | CTD | PMID:22378314 | Ptprh | Mouse | urethane | increases expression | ISO | PTPRH (Homo sapiens) | 6480464 | Urethane results in increased expression of PTPRH mRNA | CTD | PMID:28818685 | Ptprh | Mouse | valproic acid | increases methylation | ISO | PTPRH (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PTPRH gene | CTD | PMID:29154799 | Ptprh | Mouse | zinc atom | multiple interactions | ISO | PTPRH (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PTPRH mRNA | CTD | PMID:18593933 | Ptprh | Mouse | zinc(0) | multiple interactions | ISO | PTPRH (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PTPRH mRNA | CTD | PMID:18593933 | |