Mir18 (microRNA 18) - Rat Genome Database
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Gene: Mir18 (microRNA 18) Mus musculus
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Symbol: Mir18
Name: microRNA 18
RGD ID: 1608351
MGI Page MGI
Description: Involved in several processes, including animal organ development; cellular response to estrogen stimulus; and regulation of gene expression. Localizes to axon. Is expressed in several structures, including alimentary system; brain; heart; liver; and lung. Orthologous to human MIR18A (microRNA 18a).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mir; mir-18a; Mirn18; mmu-mir-; mmu-mir-18; mmu-mir-18a
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914115,281,283 - 115,281,378 (+)NCBIGRCm39mm39
GRCm3814115,043,851 - 115,043,946 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14115,043,851 - 115,043,946 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714115,443,073 - 115,443,168 (+)NCBIGRCm37mm9NCBIm37
Celera14113,634,419 - 113,634,514 (+)NCBICelera
Cytogenetic Map14E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:12007417   PMID:12919684   PMID:16381832   PMID:17369397   PMID:17604727   PMID:17656374   PMID:17765889   PMID:18311128   PMID:18329372   PMID:18791161   PMID:19416898   PMID:20215419  
PMID:20413612   PMID:20439489   PMID:20724452   PMID:21037258   PMID:21267068   PMID:21338882   PMID:21371421   PMID:21660949   PMID:21718763   PMID:21892160   PMID:21993888   PMID:22095742  
PMID:22265691   PMID:22511778   PMID:23152446   PMID:23575307   PMID:23623502   PMID:24205035   PMID:24633304   PMID:24967703   PMID:26029871   PMID:26106615   PMID:26341476   PMID:26934100  
PMID:28332553   PMID:28607111   PMID:28662367   PMID:28729362   PMID:28733035   PMID:28782600   PMID:29164562   PMID:29363860   PMID:29683732   PMID:30063763   PMID:30268986   PMID:32084370  
PMID:32296071  


Genomics

Comparative Map Data
Mir18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914115,281,283 - 115,281,378 (+)NCBIGRCm39mm39
GRCm3814115,043,851 - 115,043,946 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14115,043,851 - 115,043,946 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714115,443,073 - 115,443,168 (+)NCBIGRCm37mm9NCBIm37
Celera14113,634,419 - 113,634,514 (+)NCBICelera
Cytogenetic Map14E4NCBI
MIR18A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1391,350,751 - 91,350,821 (+)EnsemblGRCh38hg38GRCh38
GRCh381391,350,751 - 91,350,821 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371392,003,005 - 92,003,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,005 - 90,801,075 (+)NCBINCBI36hg18NCBI36
Celera1372,849,976 - 72,850,046 (+)NCBI
Cytogenetic Map13q31.3NCBI
HuRef1372,598,840 - 72,598,910 (+)NCBIHuRef
CHM1_11391,971,645 - 91,971,715 (+)NCBICHM1_1
Mir18a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21592,180,765 - 92,180,860 (+)NCBI
Rnor_6.0 Ensembl15100,180,015 - 100,180,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.015100,180,015 - 100,180,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.015103,641,038 - 103,641,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1591,045,445 - 91,045,540 (+)NCBICelera
Cytogenetic Map15q23NCBI
MIR18A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2242,478,138 - 42,478,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12242,478,138 - 42,478,229 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
MIR18A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1160,734,791 - 60,734,882 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11160,734,791 - 60,734,882 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21166,610,195 - 66,610,286 (+)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1482924828116925025Mouse
4142508Tgq25_mtriglyceride QTL 25 (mouse)Not determined84896632118896632Mouse
10755523Hgb2_mhemoglobin 2 (mouse)14105647242124902244Mouse
12903991Opfaq4_mopen field activity QTL 4 (mouse)14110973777118462433Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Krasmmu-miR-18a-3pOncomiRDBexternal_infoNANA19372139
Runx1mmu-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19114653
Hsf2mmu-miR-18a-5pMirtarbaseexternal_infoImmunofluorescence//In situ hybridization//LuciferFunctional MTI20724452
Ptenmmu-miR-18a-5pMirtarbaseexternal_infoWestern blot;qRT-PCRFunctional MTI20008935
Ptenmmu-miR-18a-5pTarbaseexternal_infoqPCRPOSITIVE
Ptenmmu-miR-18a-5pTarbaseexternal_infoWesternblitPOSITIVE
Atmmmu-miR-18a-5pOncomiRDBexternal_infoNANA23437304
Dicer1mmu-miR-18a-5pOncomiRDBexternal_infoNANA23097559
Cdk19mmu-miR-18a-5pOncomiRDBexternal_infoNANA22308110
Atmmmu-miR-18a-5pOncomiRDBexternal_infoNANA21980462
Dicer1mmu-miR-18a-5pOncomiRDBexternal_infoNANA21935572
Thbs1mmu-miR-18a-5pOncomiRDBexternal_infoNANA21402698
Esr1mmu-miR-18a-5pOncomiRDBexternal_infoNANA20080637
Esr1mmu-miR-18a-5pOncomiRDBexternal_infoNANA19684618
Esr1mmu-miR-18a-5pOncomiRDBexternal_infoNANA19027010

Predicted Targets
Summary Value
Count of predictions:31413
Count of gene targets:13038
Count of transcripts:23599
Interacting mature miRNAs:mmu-miR-18a-3p, mmu-miR-18a-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083469
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14115,043,851 - 115,043,946 (+)Ensembl
RefSeq Acc Id: NR_029736
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914115,281,283 - 115,281,378 (+)NCBI
GRCm3814115,043,851 - 115,043,946 (+)ENTREZGENE
MGSCv3714115,443,073 - 115,443,168 (+)RGD
Celera14113,634,419 - 113,634,514 (+)RGD
cM Map14 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676844 AgrOrtholog
Ensembl Genes ENSMUSG00000065403 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083469 ENTREZGENE
MGD MGI:2676844 ENTREZGENE
miRBase MI0000567 ENTREZGENE
NCBI Gene 387135 ENTREZGENE
PhenoGen Mir18 PhenoGen
RNAcentral URS000035CC3E RNACentral
  URS00005ACB9D RNACentral
  URS000075CBC1 RNACentral