Mir130a (microRNA 130a) - Rat Genome Database
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Gene: Mir130a (microRNA 130a) Mus musculus
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Symbol: Mir130a
Name: microRNA 130a
RGD ID: 1608340
MGI Page MGI
Description: Involved in several processes, including SMAD protein signal transduction; cellular response to forskolin; and hematopoietic stem cell differentiation. Is expressed in several structures, including branchial arch; central nervous system; limb bud; lung; and somite. Orthologous to human MIR130A (microRNA 130a).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-130a; Mirn; Mirn130; Mirn130a
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,571,459 - 84,571,522 (-)NCBIGRCm39mm39
GRCm38284,741,115 - 84,741,178 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,741,115 - 84,741,178 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,581,272 - 84,581,335 (-)NCBIGRCm37mm9NCBIm37
Celera286,336,310 - 86,336,373 (-)NCBICelera
Cytogenetic Map2DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12007417   PMID:12554860   PMID:12919684   PMID:15538371   PMID:16369549   PMID:16381832   PMID:16766679   PMID:17369397   PMID:17604727   PMID:17726050   PMID:18452032   PMID:19559694  
PMID:19582148   PMID:20215419   PMID:20413612   PMID:20417623   PMID:20548288   PMID:20558326   PMID:20660734   PMID:20736237   PMID:21037258   PMID:21267068   PMID:21486751   PMID:21718763  
PMID:21822254   PMID:21993888   PMID:22570807   PMID:23390484   PMID:23409087   PMID:23646144   PMID:24148619   PMID:24677715   PMID:24819345   PMID:24960162   PMID:25002578   PMID:25547017  
PMID:25681685   PMID:25751060   PMID:25858512   PMID:26436920   PMID:26458524   PMID:26565905   PMID:26667495   PMID:27111096   PMID:27827997   PMID:27834139   PMID:28518142   PMID:28755990  
PMID:28831020   PMID:28935812   PMID:29114000   PMID:29232705   PMID:29702281   PMID:29973593   PMID:30191667   PMID:31283910   PMID:31557368   PMID:31715176  


Genomics

Comparative Map Data
Mir130a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,571,459 - 84,571,522 (-)NCBIGRCm39mm39
GRCm38284,741,115 - 84,741,178 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,741,115 - 84,741,178 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,581,272 - 84,581,335 (-)NCBIGRCm37mm9NCBIm37
Celera286,336,310 - 86,336,373 (-)NCBICelera
Cytogenetic Map2DNCBI
MIR130A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1157,641,198 - 57,641,286 (+)EnsemblGRCh38hg38GRCh38
GRCh381157,641,198 - 57,641,286 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371157,408,671 - 57,408,759 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,165,246 - 57,165,334 (+)NCBINCBI36hg18NCBI36
Celera1154,765,156 - 54,765,244 (+)NCBI
Cytogenetic Map11q12.1NCBI
HuRef1153,757,429 - 53,757,517 (+)NCBIHuRef
CHM1_11157,274,889 - 57,274,977 (+)NCBICHM1_1
Mir130a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2369,822,542 - 69,822,629 (-)NCBI
Rnor_6.0 Ensembl372,141,037 - 72,141,124 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0372,141,037 - 72,141,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0378,661,697 - 78,661,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera369,178,061 - 69,178,148 (-)NCBICelera
Cytogenetic Map3q24NCBI
MIR130A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1838,543,618 - 38,543,681 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11838,543,618 - 38,543,679 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
MIR130A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl213,296,695 - 13,296,773 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1213,296,695 - 13,296,773 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2212,929,884 - 12,929,962 (-)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388608993591306Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357829Lvrq1_mliver weight QTL 1 (mouse)Not determined220892967119064359Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220892967119064359Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220892967119064359Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220892967119064359Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220892967119064359Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224334620148858457Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229417935148533014Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31324555105313225Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240995481115079684Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245457623145470727Mouse
10755526Lymph1_mlymphocyte differential 1 (mouse)25098897084988970Mouse
1300875Taste1_mtaste-saccharin preference 1 (mouse)Not determined25109283185092934Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25187293285873081Mouse
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25261767586617792Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25261767586617792Mouse
4142299Pbwg1.4_mpostnatal body weight growth 1.4 (mouse)Not determined5562407289624172Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25769377391693944Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25808964792089647Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260690268119525037Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)262000000137000000Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26317561097175769Mouse
1301405Etohr_methanol response acute (mouse)Not determined26317561097175769Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26317561097175769Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26317561097175769Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26317561097175769Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26317561097175769Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26373981097739957Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265439402162677006Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267817543101817798Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267817543101817798Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268893925102894063Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268893925102894063Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74693773114293051Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274693773129371085Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276591138110591306Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276848414103265478Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined281064989115064989Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284178143118178248Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284182854148680255Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284182854148825550Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Atxn1mmu-miR-130a-3pMirtarbaseexternal_infoWestern blotFunctional MTI18758459
Zfpm2mmu-miR-130a-3pMirtarbaseexternal_infoLuciferase reporter assay//Northern blot//Western Functional MTI19582148
Meox2mmu-miR-130a-3pMirtarbaseexternal_infoWestern blot;qRT-PCRFunctional MTI21753805
Meox2mmu-miR-130a-3pTarbaseexternal_infoqPCRPOSITIVE
Meox2mmu-miR-130a-3pTarbaseexternal_infoWesternblitPOSITIVE
Zfpm2mmu-miR-130a-3pMirecordsexternal_infoNANA19582148
Smad4mmu-miR-130a-3pOncomiRDBexternal_infoNANA23393589
Runx3mmu-miR-130a-3pOncomiRDBexternal_infoNANA22846564
Metmmu-miR-130a-3pOncomiRDBexternal_infoNANA21706050
Atg2bmmu-miR-130a-3pOncomiRDBexternal_infoNANA22350415

Predicted Targets
Summary Value
Count of predictions:23874
Count of gene targets:9512
Count of transcripts:15656
Interacting mature miRNAs:mmu-miR-130a-3p, mmu-miR-130a-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083550
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl284,741,115 - 84,741,178 (-)Ensembl
RefSeq Acc Id: NR_029544
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,571,459 - 84,571,522 (-)NCBI
GRCm38284,741,115 - 84,741,178 (-)ENTREZGENE
MGSCv37284,581,272 - 84,581,335 (-)RGD
Celera286,336,310 - 86,336,373 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Promoters
RGD ID:6877802
Promoter ID:EPDNEW_M2352
Type:single initiation site
Name:Mir130a_1
Description:Mus musculus microRNA 130a , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38284,741,114 - 84,741,174EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676816 AgrOrtholog
Ensembl Genes ENSMUSG00000065484 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083550 ENTREZGENE
MGD MGI:2676816 ENTREZGENE
miRBase MI0000156 ENTREZGENE
NCBI Gene 387149 ENTREZGENE
PhenoGen Mir130a PhenoGen
RNAcentral URS0000229ECD RNACentral
  URS0000315338 RNACentral
  URS000075D38A RNACentral