Mir132 (microRNA 132) - Rat Genome Database

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Gene: Mir132 (microRNA 132) Mus musculus
Analyze
Symbol: Mir132
Name: microRNA 132
RGD ID: 1608339
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to forskolin; long-term synaptic potentiation; and regulation of neuron maturation. Located in postsynaptic density. Is expressed in cerebellum; embryo; lung; and telencephalon. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Orthologous to human MIR132 (microRNA 132).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-132; Mirn; Mirn132; mmu-mir-1; mmu-mir-132
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,064,508 - 75,064,573 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,064,508 - 75,064,573 (+)EnsemblGRCm39 Ensembl
GRCm381175,173,682 - 75,173,747 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,173,682 - 75,173,747 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,987,184 - 74,987,249 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1182,680,626 - 82,680,691 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Upregulation of Extracellular Vesicles-Encapsulated miR-132 Released From Mesenchymal Stem Cells Attenuates Ischemic Neuronal Injury by Inhibiting Smad2/c-jun Pathway via Acvr2b Suppression. Feng B, etal., Front Cell Dev Biol. 2021 Mar 8;8:568304. doi: 10.3389/fcell.2020.568304. eCollection 2020.
2. Epigenetic mechanisms in Parkinson's disease. Feng Y, etal., J Neurol Sci. 2015 Feb 15;349(1-2):3-9. doi: 10.1016/j.jns.2014.12.017. Epub 2014 Dec 18.
3. Altered microRNA regulation in Huntington's disease models. Lee ST, etal., Exp Neurol. 2011 Jan;227(1):172-9. doi: 10.1016/j.expneurol.2010.10.012. Epub 2010 Oct 28.
4. MicroRNA-132 sensitizes nasopharyngeal carcinoma cells to cisplatin through regulation of forkhead box A1 protein. Li YL, etal., Pharmazie. 2016 Dec 1;71(12):715-718. doi: 10.1691/ph.2016.6764.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease. Wong HK, etal., Hum Mol Genet. 2013 Aug 1;22(15):3077-92. doi: 10.1093/hmg/ddt164. Epub 2013 Apr 11.
Additional References at PubMed
PMID:12007417   PMID:16369549   PMID:16381832   PMID:17369397   PMID:17604727   PMID:18452032   PMID:18723672   PMID:19559694   PMID:19843474   PMID:20010955   PMID:20159450   PMID:20215419  
PMID:20307261   PMID:20413612   PMID:20668074   PMID:21037258   PMID:21057503   PMID:21059906   PMID:21118894   PMID:21124738   PMID:21206919   PMID:21267068   PMID:21372146   PMID:21611182  
PMID:21718763   PMID:21892154   PMID:21892155   PMID:21945804   PMID:21993888   PMID:22144232   PMID:22246100   PMID:22315408   PMID:22328530   PMID:22659469   PMID:22693596   PMID:22706759  
PMID:22874921   PMID:22897173   PMID:23011132   PMID:23184980   PMID:23264652   PMID:23520022   PMID:23658634   PMID:23780851   PMID:23818645   PMID:24381269   PMID:24431455   PMID:24657774  
PMID:24877561   PMID:25635942   PMID:25751060   PMID:25813747   PMID:25858512   PMID:25862525   PMID:25885346   PMID:25945589   PMID:26084022   PMID:26107383   PMID:26121747   PMID:26319558  
PMID:26362250   PMID:26371188   PMID:26773099   PMID:26921097   PMID:26947125   PMID:27165825   PMID:27422605   PMID:27484949   PMID:27539363   PMID:27579184   PMID:28065883   PMID:28244951  
PMID:28314201   PMID:28381526   PMID:28423315   PMID:28429770   PMID:28448626   PMID:28534484   PMID:28592747   PMID:28615644   PMID:28670439   PMID:28807666   PMID:29017096   PMID:29661834  
PMID:29678773   PMID:29846108   PMID:29982852   PMID:30342060   PMID:30400037   PMID:30672723   PMID:30679653   PMID:30809933   PMID:30833344   PMID:31004309   PMID:31204523   PMID:31364135  
PMID:31669733   PMID:31858814   PMID:31918917   PMID:31940779   PMID:32054528   PMID:32409785   PMID:32595040   PMID:32600449   PMID:32658123   PMID:32965772   PMID:33443169   PMID:34033742  
PMID:34182078   PMID:34346000   PMID:34359879   PMID:34983831   PMID:35053378   PMID:35163786   PMID:36121415   PMID:37036545  


Genomics

Comparative Map Data
Mir132
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,064,508 - 75,064,573 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,064,508 - 75,064,573 (+)EnsemblGRCm39 Ensembl
GRCm381175,173,682 - 75,173,747 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,173,682 - 75,173,747 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,987,184 - 74,987,249 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1182,680,626 - 82,680,691 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
MIR132
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38172,049,908 - 2,050,008 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl172,049,908 - 2,050,008 (-)EnsemblGRCh38hg38GRCh38
GRCh37171,953,202 - 1,953,302 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,899,951 - 1,900,051 (-)NCBINCBI36Build 36hg18NCBI36
Celera171,969,847 - 1,969,947 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef171,849,221 - 1,849,321 (-)NCBIHuRef
CHM1_1171,961,969 - 1,962,069 (-)NCBICHM1_1
T2T-CHM13v2.0171,937,812 - 1,937,912 (-)NCBIT2T-CHM13v2.0
Mir132
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,522,033 - 60,522,133 (+)NCBIGRCr8
mRatBN7.21060,023,696 - 60,023,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,023,696 - 60,023,796 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1064,670,305 - 64,670,405 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01064,175,887 - 64,175,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,638,269 - 59,638,369 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01062,014,995 - 62,015,095 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,014,995 - 62,015,095 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,729,385 - 61,729,485 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1059,053,649 - 59,053,749 (+)NCBICelera
Cytogenetic Map10q24NCBI
MIR132
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1946,153,531 - 46,153,590 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl946,153,511 - 46,153,611 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha945,303,625 - 45,303,684 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0946,984,381 - 46,984,440 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl946,984,361 - 46,984,461 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1945,751,431 - 45,751,490 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0946,045,771 - 46,045,830 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0946,100,805 - 46,100,864 (-)NCBIUU_Cfam_GSD_1.0
MIR132
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1248,162,614 - 48,162,714 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11248,162,625 - 48,162,702 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21250,015,722 - 50,015,799 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir132
4 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:12735
Count of gene targets:6715
Count of transcripts:10688
Interacting mature miRNAs:mmu-miR-132-3p, mmu-miR-132-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083603
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,064,508 - 75,064,573 (+)Ensembl
GRCm38.p6 Ensembl1175,173,682 - 75,173,747 (+)Ensembl
RefSeq Acc Id: NR_029546
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391175,064,508 - 75,064,573 (+)NCBI
GRCm381175,173,682 - 75,173,747 (+)ENTREZGENE
MGSCv371174,987,184 - 74,987,249 (+)RGD
Celera1182,680,626 - 82,680,691 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Promoters
RGD ID:8675522
Promoter ID:EPDNEW_M15792
Type:multiple initiation site
Name:Mir132_1
Description:Mus musculus microRNA 132 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381175,173,605 - 75,173,665EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676817 AgrOrtholog
Ensembl Genes ENSMUSG00000065537 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083603 ENTREZGENE
MGD MGI:2676817 ENTREZGENE
miRBase MI0000158 ENTREZGENE
NCBI Gene 387150 ENTREZGENE
PhenoGen Mir132 PhenoGen
RNAcentral URS000032AEB0 RNACentral
  URS00006054DA RNACentral
  URS000075ABE4 RNACentral