Mir152 (microRNA 152) - Rat Genome Database

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Gene: Mir152 (microRNA 152) Mus musculus
Analyze
Symbol: Mir152
Name: microRNA 152
RGD ID: 1608321
MGI Page MGI
Description: Acts upstream of or within cellular response to ethanol; cellular response to leukemia inhibitory factor; and sensory perception of sound. Is expressed in embryo; gut; lung; and pancreas. Human ortholog(s) of this gene implicated in colorectal cancer; colorectal carcinoma; endometrial carcinoma; and stomach cancer. Orthologous to human MIR152 (microRNA 152).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-152; Mirn; Mirn152; mmu-mir-1; mmu-mir-152
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,741,219 - 96,741,291 (+)NCBIGRCm39mm39
GRCm39 Ensembl1196,741,219 - 96,741,291 (+)Ensembl
GRCm381196,850,393 - 96,850,465 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,850,393 - 96,850,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,711,707 - 96,711,779 (+)NCBIGRCm37mm9NCBIm37
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
1. Chen H, etal., J Cancer. 2016 Feb 5;7(5):490-9. doi: 10.7150/jca.12351. eCollection 2016.
2. Chen JF, etal., Zhonghua Nan Ke Xue. 2017 Jul;23(7):603-608.
3. Chen X, etal., Mutagenesis. 2014 Nov;29(6):401-7. doi: 10.1093/mutage/geu050. Epub 2014 Sep 26.
4. Chen Y, etal., J Gastrointest Surg. 2010 Jul;14(7):1170-9. doi: 10.1007/s11605-010-1202-2. Epub 2010 Apr 27.
5. Feng L, etal., Pharm Biol. 2019 Dec;57(1):586-594. doi: 10.1080/13880209.2019.1657153.
6. Hu L, etal., Int Immunopharmacol. 2020 Jan 23;80:106141. doi: 10.1016/j.intimp.2019.106141.
7. Li B, etal., Tumour Biol. 2016 Jan 28.
8. Li L, etal., Exp Ther Med. 2019 Jul;18(1):425-434. doi: 10.3892/etm.2019.7595. Epub 2019 May 20.
9. Li Y, etal., Mol Med Rep. 2017 Feb;15(2):948-956. doi: 10.3892/mmr.2016.6059. Epub 2016 Dec 19.
10. Miao CG, etal., Biochimie. 2014 Nov;106:149-56. doi: 10.1016/j.biochi.2014.08.016. Epub 2014 Sep 4.
11. Pavicic W, etal., Mol Med. 2011;17(7-8):726-35. doi: 10.2119/molmed.2010.00239. Epub 2011 Feb 9.
12. RGD automated import pipeline for gene-chemical interactions
13. Wang F, etal., Tumour Biol. 2016 Apr;37(4):4945-53. doi: 10.1007/s13277-015-4340-z. Epub 2015 Nov 3.
14. Wang Y, etal., Oncotarget. 2017 Apr 25;8(17):28125-28134. doi: 10.18632/oncotarget.15924.
15. Watahiki A, etal., Int J Mol Sci. 2013 Apr 10;14(4):7757-70. doi: 10.3390/ijms14047757.
16. Xu Q, etal., J Mol Cell Biol. 2013 Feb;5(1):3-13. doi: 10.1093/jmcb/mjs049. Epub 2012 Aug 29.
17. Yin T, etal., Pathol Res Pract. 2019 Jun;215(6):152406. doi: 10.1016/j.prp.2019.03.034. Epub 2019 Apr 1.
18. Yu F, etal., J Cell Mol Med. 2015 Nov;19(11):2617-32. doi: 10.1111/jcmm.12655. Epub 2015 Aug 10.
19. Zhang H, etal., Oncol Rep. 2018 Sep;40(3):1803-1812. doi: 10.3892/or.2018.6553. Epub 2018 Jul 10.
20. Zhang H, etal., Oncol Res. 2019 Feb 21;27(3):335-340. doi: 10.3727/096504018X15252202178408. Epub 2018 Aug 21.
21. Zhang L, etal., Eur Rev Med Pharmacol Sci. 2019 May;23(9):3553-3560. doi: 10.26355/eurrev_201905_17776.
22. Zhang S, etal., Dig Dis Sci. 2017 Nov;62(11):3050-3058. doi: 10.1007/s10620-017-4759-8. Epub 2017 Sep 18.
Additional References at PubMed
PMID:12007417   PMID:15538371   PMID:16369549   PMID:16381832   PMID:16766679   PMID:17369397   PMID:17604727   PMID:17936263   PMID:18452032   PMID:19091803   PMID:19559694   PMID:20215419  
PMID:20413612   PMID:20439489   PMID:20589883   PMID:20668074   PMID:21037258   PMID:21068402   PMID:21267068   PMID:21822254   PMID:22144232   PMID:23646144   PMID:26996529   PMID:28472596  
PMID:29358670   PMID:29508126   PMID:30106118   PMID:30551500   PMID:30657545   PMID:30668148   PMID:31326116   PMID:31893334   PMID:32718473   PMID:33574984  


Genomics

Comparative Map Data
Mir152
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,741,219 - 96,741,291 (+)NCBIGRCm39mm39
GRCm39 Ensembl1196,741,219 - 96,741,291 (+)Ensembl
GRCm381196,850,393 - 96,850,465 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,850,393 - 96,850,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,711,707 - 96,711,779 (+)NCBIGRCm37mm9NCBIm37
Cytogenetic Map11DNCBI
MIR152
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1748,037,161 - 48,037,247 (-)EnsemblGRCh38hg38GRCh38
GRCh381748,037,161 - 48,037,247 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371746,114,527 - 46,114,613 (-)NCBIGRCh37GRCh37hg19GRCh37
Celera1742,567,346 - 42,567,432 (-)NCBI
Cytogenetic Map17q21.32NCBI
HuRef1741,483,141 - 41,483,227 (-)NCBIHuRef
CHM1_11746,179,516 - 46,179,602 (-)NCBICHM1_1
Mir152
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21081,832,936 - 81,833,020 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1081,832,936 - 81,833,020 (+)Ensembl
Rnor_6.01084,719,319 - 84,719,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,719,319 - 84,719,403 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,512,232 - 84,512,316 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1080,594,606 - 80,594,690 (+)NCBICelera
Cytogenetic Map10q31NCBI
MIR152
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,335,161 - 24,335,219 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,335,146 - 24,335,225 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha923,800,932 - 23,800,990 (-)NCBI
ROS_Cfam_1.0925,128,568 - 25,128,626 (-)NCBI
UMICH_Zoey_3.1923,898,331 - 23,898,389 (-)NCBI
UNSW_CanFamBas_1.0924,158,972 - 24,159,030 (-)NCBI
UU_Cfam_GSD_1.0924,286,093 - 24,286,151 (-)NCBI
MIR152
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,292,251 - 24,292,336 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,292,249 - 24,292,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,289,536 - 24,289,615 (-)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179922933104611872Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1181000000102000000Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185954085119954085Mouse
15039374Adip29_madiposity 29 (mouse)1186717494120717494Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186717494120717494Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186717494120717494Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187800372103383289Mouse
1301491Abbp4_mA/J and C57BL/6 blood pressure 4 (mouse)Not determined118880876299190771Mouse
1301313Pas5a_mpulmonary adenoma susceptibility 5a (mouse)Not determined118907597898974942Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1193048547112653728Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194172953118131898Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194300000119000000Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94546357118131898Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195513139122082543Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195513139122082543Mouse
14700796Syncq9_msynovial calcification QTL 9 (mouse)119604700097102000Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196246848122082543Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196285639108915558Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Camk2ammu-miR-152-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21068402
Tgfammu-miR-152-3pOncomiRDBexternal_infoNANA23460133
Dnmt1mmu-miR-152-3pOncomiRDBexternal_infoNANA23318422
Dnmt1mmu-miR-152-3pOncomiRDBexternal_infoNANA22935141
E2f3mmu-miR-152-3pOncomiRDBexternal_infoNANA21868754
Dnmt1mmu-miR-152-3pOncomiRDBexternal_infoNANA20841484
Dnmt1mmu-miR-152-3pOncomiRDBexternal_infoNANA20578129
Dnmt1mmu-miR-152-3pOncomiRDBexternal_infoNANA20146264

Predicted Targets
Summary Value
Count of predictions:23530
Count of gene targets:9902
Count of transcripts:16700
Interacting mature miRNAs:mmu-miR-152-3p, mmu-miR-152-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083581
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1196,741,219 - 96,741,291 (+)Ensembl
GRCm38.p6 Ensembl1196,850,393 - 96,850,465 (+)Ensembl
RefSeq Acc Id: NR_029562
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391196,741,219 - 96,741,291 (+)NCBI
GRCm381196,850,393 - 96,850,465 (+)ENTREZGENE
MGSCv371196,711,707 - 96,711,779 (+)RGD
cM Map11 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676837 AgrOrtholog
Ensembl Genes ENSMUSG00000065515 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083581 ENTREZGENE
MGD MGI:2676837 ENTREZGENE
miRBase MI0000174 ENTREZGENE
NCBI Gene 387170 ENTREZGENE
PhenoGen Mir152 PhenoGen
RNAcentral URS00003AFD9B RNACentral
  URS000059EF7A RNACentral
  URS000075E619 RNACentral