Mir188 (microRNA 188) - Rat Genome Database

Name: Mir188
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Mir188 (microRNA 188) Mus musculus

Analyze

Symbol:

Mir188

Name:

microRNA 188

RGD ID:

1608308

MGI Page

MGI

Description:

Is expressed in cranial ganglion; dorsal root ganglion; and neural retina. Orthologous to human MIR188 (microRNA 188).

Type:

ncrna

RefSeq Status:

PROVISIONAL

Also known as:

mir-188; Mirn; Mirn188; mmu-mir-1; mmu-mir-188

RGD Orthologs

Human

Rat

Dog

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	7,114,228 - 7,114,295 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	X	7,114,228 - 7,114,295 (-)	Ensembl
GRCm38	X	7,247,989 - 7,248,056 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	7,247,989 - 7,248,056 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	6,825,115 - 6,825,182 (-)	NCBI	GRCm37		mm9	NCBIm37
Celera	X	4,223,780 - 4,223,847 (+)	NCBI		Celera
Cytogenetic Map	X	A1.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Contrast-Induced Nephropathy (ISO)

Dent Disease 1 (ISO)

Myocardial Reperfusion Injury (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methoxyethanol (ISO)

acrolein (ISO)

arsane (EXP)

arsenic atom (EXP)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (ISO)

bleomycin A2 (ISO)

cisplatin (ISO)

decabromodiphenyl ether (ISO)

hexanal (ISO)

hydrogen peroxide (ISO)

methimazole (EXP)

p-cresol (EXP)

paracetamol (ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (EXP)

streptozocin (EXP)

titanium dioxide (EXP)

tributyl phosphate (EXP)

trichloroethene (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone marrow development (IDA,IMP)

cell aging (IDA)

regulation of fat cell differentiation (IDA,IMP)

regulation of gene expression (IMP)

regulation of osteoblast differentiation (IDA,IMP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal fat cell differentiation (IAGP)

abnormal fat cell morphology (IAGP)

abnormal skeleton development (IAGP)

decreased bone trabecular spacing (IAGP)

decreased internal diameter of femur (IAGP)

increased bone ossification (IAGP)

increased bone stiffness (IAGP)

increased bone strength (IAGP)

increased bone trabecula number (IAGP)

increased bone volume (IAGP)

increased femur compact bone thickness (IAGP)

increased osteoblast cell number (IAGP)

increased trabecular bone volume (IAGP)

References

References - curated


1.	RGD automated import pipeline
2.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	RGD automated import pipeline for gene-chemical interactions
4.	Sun SQ, etal., J Am Heart Assoc. 2016 Aug 15;5(8). pii: JAHA.116.004138. doi: 10.1161/JAHA.116.004138.

Additional References at PubMed

PMID:12554859	PMID:15538371	PMID:16381832	PMID:17369397	PMID:17604727	PMID:20215419	PMID:20413612	PMID:21037258	PMID:21267068	PMID:22570807	PMID:25378159	PMID:25751060
PMID:25858075	PMID:27708404	PMID:28640956	PMID:29663375	PMID:29908885	PMID:30253270	PMID:32377998

Genomics

Comparative Map Data

Mir188
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	7,114,228 - 7,114,295 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	X	7,114,228 - 7,114,295 (-)	Ensembl
GRCm38	X	7,247,989 - 7,248,056 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	7,247,989 - 7,248,056 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	6,825,115 - 6,825,182 (-)	NCBI	GRCm37		mm9	NCBIm37
Celera	X	4,223,780 - 4,223,847 (+)	NCBI		Celera
Cytogenetic Map	X	A1.1	NCBI

MIR188
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	X	50,003,503 - 50,003,588 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	X	50,003,503 - 50,003,588 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	X	49,768,109 - 49,768,194 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	49,654,848 - 49,654,933 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	X	53,837,336 - 53,837,421 (+)	NCBI
Cytogenetic Map	X	p11.23	NCBI
HuRef	X	47,238,055 - 47,238,140 (+)	NCBI		HuRef
CHM1_1	X	49,847,897 - 49,847,982 (+)	NCBI		CHM1_1

Mir188
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	15,247,715 - 15,247,794 (+)	NCBI
Rnor_6.0 Ensembl	X	16,110,270 - 16,110,349 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	X	16,110,270 - 16,110,349 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	X	16,895,394 - 16,895,473 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	X	15,327,046 - 15,327,125 (+)	NCBI		Celera
Cytogenetic Map	X	q12	NCBI

MIR188
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	X	42,775,058 - 42,775,143 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	X	42,775,058 - 42,775,143 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1302195	Pbwg10_m	postnatal body weight growth 10 (mouse)			Not determined		X	1	26335934	Mouse

miRNA Target Status

Predicted Targets

	Summary Value
Count of predictions:	21056
Count of gene targets:	9908
Count of transcripts:	16600
Interacting mature miRNAs:	mmu-miR-188-3p, mmu-miR-188-5p
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_029574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ560730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL663104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	LM608310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000083464

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	X	7,247,989 - 7,248,056 (-)	Ensembl

RefSeq Acc Id:

NR_029574

RefSeq Status:

PROVISIONAL

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	7,114,228 - 7,114,295 (-)	NCBI
GRCm38	X	7,247,989 - 7,248,056 (-)	ENTREZGENE
MGSCv37	X	6,825,115 - 6,825,182 (-)	RGD
Celera	X	4,223,780 - 4,223,847 (+)	RGD
cM Map	X		ENTREZGENE

Sequence:

show sequence

TCTCACATCCCTTGCATGGTGGAGGGTGAGCTCTCTGAAAACCCCTCCCACATGCAGGGTTTGC
AGGA

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2676852	AgrOrtholog
Ensembl Genes	ENSMUSG00000065398	Ensembl, ENTREZGENE
Ensembl Transcript	ENSMUST00000083464	ENTREZGENE
MGD	MGI:2676852	ENTREZGENE
miRBase	MI0000230	ENTREZGENE
NCBI Gene	387183	ENTREZGENE
PhenoGen	Mir188	PhenoGen
RNAcentral	URS0000083D87	RNACentral
	URS000061AB33	RNACentral
	URS000075AB10	RNACentral

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD