Mir219a-1 (microRNA 219a-1) - Rat Genome Database

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Gene: Mir219a-1 (microRNA 219a-1) Mus musculus
Analyze
Symbol: Mir219a-1
Name: microRNA 219a-1
RGD ID: 1608228
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to growth factor stimulus; cellular response to leukemia inhibitory factor; and regulation of nervous system development. Part of RISC complex. Is expressed in several structures, including central nervous system; eye; future brain; gonad; and hemolymphoid system gland. Orthologous to human MIR219A1 (microRNA 219a-1).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-219a-1; Mir219-1; Mirn21; Mirn219-1; mmu-mir-219a-1
RGD Orthologs
Human
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,243,957 - 34,244,066 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,243,957 - 34,244,066 (-)EnsemblGRCm39 Ensembl
GRCm381734,024,983 - 34,025,092 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,024,983 - 34,025,092 (-)EnsemblGRCm38mm10GRCm38
MGSCv371734,161,928 - 34,162,037 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1736,771,112 - 36,771,221 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IDA)

Molecular Function

References
Additional References at PubMed
PMID:12624257   PMID:15634332   PMID:16369549   PMID:16381832   PMID:17369397   PMID:17597072   PMID:17604727   PMID:18452032   PMID:19559694   PMID:20215419   PMID:20223197   PMID:20413612  
PMID:20439489   PMID:21037258   PMID:21267068   PMID:23185045   PMID:24608432   PMID:26036346   PMID:26212661   PMID:26965827   PMID:27599867   PMID:27855391   PMID:28145507   PMID:28350989  
PMID:29478199   PMID:30657544   PMID:31628427   PMID:32249206   PMID:33174081   PMID:33669304   PMID:33822434   PMID:34556635  


Genomics

Comparative Map Data
Mir219a-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,243,957 - 34,244,066 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,243,957 - 34,244,066 (-)EnsemblGRCm39 Ensembl
GRCm381734,024,983 - 34,025,092 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,024,983 - 34,025,092 (-)EnsemblGRCm38mm10GRCm38
MGSCv371734,161,928 - 34,162,037 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1736,771,112 - 36,771,221 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
MIR219A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,207,835 - 33,207,944 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl633,207,835 - 33,207,944 (+)EnsemblGRCh38hg38GRCh38
GRCh37633,175,612 - 33,175,721 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,283,589 - 33,283,698 (+)NCBINCBI36Build 36hg18NCBI36
Celera634,729,976 - 34,730,085 (+)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,917,657 - 32,917,766 (+)NCBIHuRef
CHM1_1633,177,490 - 33,177,599 (+)NCBICHM1_1
T2T-CHM13v2.0633,029,188 - 33,029,297 (+)NCBIT2T-CHM13v2.0
Mir219a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,831,580 - 4,831,689 (+)NCBIGRCr8
mRatBN7.2204,829,687 - 4,829,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,829,687 - 4,829,796 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,581,479 - 5,581,588 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,943,233 - 4,943,342 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,424,110 - 5,424,219 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,816,158 - 3,816,267 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,816,158 - 3,816,267 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,895,489 - 5,895,598 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera206,429,872 - 6,429,981 (+)NCBICelera
Cytogenetic Map20p12NCBI

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:10170
Count of gene targets:5187
Count of transcripts:7804
Interacting mature miRNAs:mmu-miR-219a-1-3p, mmu-miR-219a-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
11038694Pas19_mpulmonary adenoma susceptibility 19 (mouse)172971116434754437Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173266042635520036Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173381972136250180Mouse
1301759Sles1_msystemic lupus erythmatosus suppressor 1 (mouse)Not determined173421989035175937Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083621
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,243,957 - 34,244,066 (-)Ensembl
GRCm38.p6 Ensembl1734,024,983 - 34,025,092 (-)Ensembl
RefSeq Acc Id: NR_029800
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,243,957 - 34,244,066 (-)NCBI
GRCm381734,024,983 - 34,025,092 (-)ENTREZGENE
MGSCv371734,161,928 - 34,162,037 (-)RGD
Celera1736,771,112 - 36,771,221 (-)RGD
cM Map17 ENTREZGENE
Sequence:
Promoters
RGD ID:13675638
Promoter ID:EPDNEW_M21968
Type:single initiation site
Name:Mir219a-1_1
Description:Mus musculus microRNA 219a-1 (Mir219a-1), microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381734,025,145 - 34,025,205EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3618753 AgrOrtholog
Ensembl Genes ENSMUSG00000065555 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083621 ENTREZGENE
MGD MGI:3618753 ENTREZGENE
miRBase MI0000702 ENTREZGENE
NCBI Gene 723823 ENTREZGENE
PhenoGen Mir219a-1 PhenoGen
RNAcentral URS00004980B0 RNACentral
  URS0000565C8D RNACentral
  URS000075E24C RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-05-27 Mir219a-1  microRNA 219a-1  Mir219-1  microRNA 219-1  Symbol and/or name change 5135510 APPROVED