Mir326 (microRNA 326) - Rat Genome Database
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Gene: Mir326 (microRNA 326) Mus musculus
Analyze
Symbol: Mir326
Name: microRNA 326
RGD ID: 1608212
MGI Page MGI
Description: Involved in positive regulation of T-helper 17 cell differentiation; regulation of gene expression; and sensory perception of sound. Localizes to RISC complex. Is expressed in alimentary system; appendicular skeleton; and pelvic girdle skeleton. Orthologous to human MIR326 (microRNA 326).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-326; Mirn; Mirn326; mmu-mir-3; mmu-mir-326
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,201,476 - 99,201,570 (+)NCBIGRCm39mm39
GRCm38799,552,269 - 99,552,363 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl799,552,269 - 99,552,363 (+)EnsemblGRCm38mm10GRCm38
MGSCv377106,700,779 - 106,700,873 (+)NCBIGRCm37mm9NCBIm37
Celera799,877,151 - 99,877,245 (+)NCBICelera
Cytogenetic Map7E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IDA)

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:17369397   PMID:17604727   PMID:17936263   PMID:19838199   PMID:20215419   PMID:20413612   PMID:21037258   PMID:21267068   PMID:21822254   PMID:22144232   PMID:23185045  
PMID:23646144   PMID:24617895   PMID:26107383   PMID:26773046   PMID:28748390   PMID:29181619   PMID:29727715   PMID:31135066   PMID:31270675   PMID:31385301   PMID:31972179  


Genomics

Comparative Map Data
Mir326
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,201,476 - 99,201,570 (+)NCBIGRCm39mm39
GRCm38799,552,269 - 99,552,363 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl799,552,269 - 99,552,363 (+)EnsemblGRCm38mm10GRCm38
MGSCv377106,700,779 - 106,700,873 (+)NCBIGRCm37mm9NCBIm37
Celera799,877,151 - 99,877,245 (+)NCBICelera
Cytogenetic Map7E1NCBI
MIR326
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1175,335,092 - 75,335,186 (-)EnsemblGRCh38hg38GRCh38
GRCh381175,335,092 - 75,335,186 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371175,046,136 - 75,046,230 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,723,783 - 74,723,877 (-)NCBINCBI36hg18NCBI36
Celera1172,352,689 - 72,352,783 (-)NCBI
Cytogenetic Map11q13.4NCBI
HuRef1171,343,379 - 71,343,473 (-)NCBIHuRef
CHM1_11174,929,706 - 74,929,800 (-)NCBICHM1_1
Mir326
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21153,854,029 - 153,854,123 (+)NCBI
Rnor_6.0 Ensembl1164,518,401 - 164,518,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01164,518,401 - 164,518,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01170,722,071 - 170,722,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1151,940,711 - 151,940,805 (+)NCBICelera
Cytogenetic Map1q32NCBI
MIR326
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2123,240,463 - 23,240,553 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12123,240,463 - 23,240,553 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
MIR326
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl99,581,944 - 9,582,034 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.199,581,944 - 9,582,034 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2910,800,191 - 10,800,281 (-)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730500000109400000Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736580590116817642Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined740024463103860803Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745512542119094307Mouse
13208555Lgth10_mbody length 10 (mouse)752000000126000000Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)755169841117223580Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)757300000134400000Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)762100000121800000Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)762100000124100000Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)762200000103100000Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765600000126900000Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)766139778100139778Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)766139778100139778Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767640886101641032Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767640886101641032Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767640886101641032Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)768200000105800000Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)768200000119900000Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)768200000124600000Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)768200000125400000Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768716387102716494Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)770300000120900000Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770493929104494171Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772614164106614164Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773400000126100000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)774076757108076757Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)775200000122600000Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)775200000122600000Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775745007109745138Mouse
14746989Manh62_mmandible shape 62 (mouse)776093321110093321Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)779000000137300000Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80902474114902584Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780902474114902584Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)781200000127100000Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781600000124600000Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781800000126900000Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)782200000126900000Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785400000124600000Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785716387112934612Mouse
1301647Elpt_melevated leptin (mouse)Not determined786850979120851122Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787394725121394859Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787394725121394859Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787394725121394859Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787493929119886157Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787600000126900000Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787600000126900000Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)788200000108500000Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791883789125883949Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791883789125883949Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793792641127792834Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798565687132565775Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798795739132795739Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Smommu-miR-326-3pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI20216554
Ets1mmu-miR-326-3pMirtarbaseexternal_infoELISA//Flow//GFP reporter assay//Immunoblot//In siFunctional MTI19838199
Pkmmmu-miR-326-5pOncomiRDBexternal_infoNANA20667897
Notch1mmu-miR-326-5pOncomiRDBexternal_infoNANA19955368
Abcc1mmu-miR-326-5pOncomiRDBexternal_infoNANA19883630

Predicted Targets
Summary Value
Count of predictions:66754
Count of gene targets:19872
Count of transcripts:41906
Interacting mature miRNAs:mmu-miR-326-3p, mmu-miR-326-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083637
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl799,552,269 - 99,552,363 (+)Ensembl
RefSeq Acc Id: NR_029760
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39799,201,476 - 99,201,570 (+)NCBI
GRCm38799,552,269 - 99,552,363 (+)ENTREZGENE
MGSCv377106,700,779 - 106,700,873 (+)RGD
Celera799,877,151 - 99,877,245 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Promoters
RGD ID:8664887
Promoter ID:EPDNEW_M10475
Type:single initiation site
Name:Mir326_1
Description:Mus musculus microRNA 326 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38799,552,350 - 99,552,410EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619338 AgrOrtholog
Ensembl Genes ENSMUSG00000065571 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083637 ENTREZGENE
MGD MGI:3619338 ENTREZGENE
miRBase MI0000598 ENTREZGENE
NCBI Gene 723840 ENTREZGENE
PhenoGen Mir326 PhenoGen
RNAcentral URS00000AF446 RNACentral
  URS000032B538 RNACentral
  URS0000670596 RNACentral