Mir377 (microRNA 377) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mir377 (microRNA 377) Mus musculus
Analyze
Symbol: Mir377
Name: microRNA 377
RGD ID: 1608197
MGI Page MGI
Description: Involved in energy homeostasis. Acts upstream of or within cellular response to phenylalanine. Orthologous to human MIR377 (microRNA 377).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-377; Mirn; Mirn377; mmu-mir-3; mmu-mir-377
RGD Orthologs
Human
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912109,706,944 - 109,707,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12109,706,944 - 109,707,011 (+)EnsemblGRCm39 Ensembl
GRCm3812109,740,510 - 109,740,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12109,740,510 - 109,740,577 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712110,978,720 - 110,978,787 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera12110,937,740 - 110,937,807 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. miR-377 inhibited tumorous behaviors of non-small cell lung cancer through directly targeting CDK6. Zhang J, etal., Eur Rev Med Pharmacol Sci. 2016 Nov;20(21):4494-4499.
Additional References at PubMed
PMID:15310658   PMID:15538371   PMID:16274478   PMID:16381832   PMID:17369397   PMID:17604727   PMID:20215419   PMID:20413612   PMID:21037258   PMID:21267068   PMID:21822254   PMID:25124681  
PMID:26107383   PMID:26822703   PMID:28137588   PMID:30232292   PMID:30408478   PMID:30612004   PMID:31545231   PMID:32373927   PMID:35124003   PMID:35168080   PMID:36267816   PMID:36504038  
PMID:36719624   PMID:36892682   PMID:37817032  


Genomics

Comparative Map Data
Mir377
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912109,706,944 - 109,707,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12109,706,944 - 109,707,011 (+)EnsemblGRCm39 Ensembl
GRCm3812109,740,510 - 109,740,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12109,740,510 - 109,740,577 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712110,978,720 - 110,978,787 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera12110,937,740 - 110,937,807 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.56NCBI
MIR377
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,062,050 - 101,062,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,062,050 - 101,062,118 (+)EnsemblGRCh38hg38GRCh38
GRCh3714101,528,387 - 101,528,455 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,598,139 - 100,598,207 (+)NCBINCBI36Build 36hg18NCBI36
Celera1481,584,448 - 81,584,516 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1481,711,760 - 81,711,828 (+)NCBIHuRef
CHM1_114101,467,409 - 101,467,477 (+)NCBICHM1_1
T2T-CHM13v2.01495,297,436 - 95,297,504 (+)NCBIT2T-CHM13v2.0
Mir377
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86134,576,456 - 134,576,527 (+)NCBIGRCr8
mRatBN7.26128,755,051 - 128,755,122 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx6128,934,290 - 128,934,361 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,230,122 - 129,230,193 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06128,591,747 - 128,591,818 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06133,890,690 - 133,890,761 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6133,890,646 - 133,890,779 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,053,047 - 143,053,118 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6126,339,430 - 126,339,501 (+)NCBICelera
Cytogenetic Map6q32NCBI
MIR377
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1869,290,937 - 69,291,005 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha868,809,084 - 68,809,152 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0869,572,589 - 69,572,657 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1869,236,132 - 69,236,200 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0869,302,226 - 69,302,294 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0869,700,224 - 69,700,292 (+)NCBIUU_Cfam_GSD_1.0

miRNA Target Status (No longer updated)

Predicted Targets
Summary Value
Count of predictions:23254
Count of gene targets:9677
Count of transcripts:16250
Interacting mature miRNAs:mmu-miR-377-3p, mmu-miR-377-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128213Lwq23_mliver weight QTL 10 (mouse)1280956708113383533Mouse
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285961579119961683Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292750025120092757Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292750025120092757Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292936097120092757Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296860337120092757Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288052874120092757Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
11039526Ccc1_mcolitis susceptibility in the Collaborative Cross 1 (mouse)1293528334111028223Mouse
4141297Plyid_mPolymeric IgA dominance (mouse)Not determined109183385115885122Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288052874120092757Mouse
4141610Tailaq1_mtail length adjusted QTL 1 (mouse)Not determined80956708113383533Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289939031120092757Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282666396116666396Mouse
10412156Nociq3_mnociceptive sensitivity inflammatory QTL 3 (mouse)Not determined1286396075114831653Mouse
13524842Ppiq10a_mprepulse inhibition QTL 10a (mouse)1277512220111512220Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283532075117532224Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291222515120092757Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283532075117532224Mouse
4141335W6q10_mweight 6 weeks QTL 10 (mouse)Not determined80956708113383533Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289664071120092757Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296860337120092757Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288308354120092757Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290308268120092757Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294146064120092757Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102024665120092757Mouse
27226793Feml10_mfemur length 10, 5 week (mouse)1268346774113363620Mouse
4142401Egq10_mearly growth QTL 10 (mouse)Not determined80956708113383533Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293264461120092757Mouse
13524849Ppiq11a_mprepulse inhibition QTL 11a (mouse)1280989143114989143Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000083504
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12109,706,944 - 109,707,011 (+)Ensembl
GRCm38.p6 Ensembl12109,740,510 - 109,740,577 (+)Ensembl
RefSeq Acc Id: NR_029878
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912109,706,944 - 109,707,011 (+)NCBI
GRCm3812109,740,510 - 109,740,577 (+)ENTREZGENE
MGSCv3712110,978,720 - 110,978,787 (+)RGD
Celera12110,937,740 - 110,937,807 (+)RGD
cM Map12 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619382 AgrOrtholog
Ensembl Genes ENSMUSG00000065438 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083504 ENTREZGENE
MGD MGI:3619382 ENTREZGENE
miRBase MI0000794 ENTREZGENE
NCBI Gene 723857 ENTREZGENE
PhenoGen Mir377 PhenoGen
RNAcentral URS000007F792 RNACentral
  URS000036BEF1 RNACentral
  URS000075E879 RNACentral