Mir425 (microRNA 425) - Rat Genome Database
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Gene: Mir425 (microRNA 425) Mus musculus
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Symbol: Mir425
Name: microRNA 425
RGD ID: 1608190
MGI Page MGI
Description: Involved in cellular response to amino acid stimulus; cellular response to lipopolysaccharide; and long-term synaptic potentiation. Orthologous to human MIR425 (microRNA 425).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mirn; Mirn425; mmu-mir-4; mmu-mir-425
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,445,976 - 108,446,060 (+)NCBIGRCm39mm39
GRCm389108,568,777 - 108,568,861 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,568,777 - 108,568,861 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,471,108 - 108,471,192 (+)NCBIGRCm37mm9NCBIm37
Celera9108,180,018 - 108,180,102 (+)NCBICelera
Cytogenetic Map9F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15538371   PMID:16381832   PMID:17369397   PMID:17604727   PMID:18762567   PMID:19883498   PMID:20215419   PMID:20413612   PMID:20548288   PMID:21267068   PMID:25858512   PMID:29331376  
PMID:29535266   PMID:30822529   PMID:31383850   PMID:32002587  


Genomics

Comparative Map Data
Mir425
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,445,976 - 108,446,060 (+)NCBIGRCm39mm39
GRCm389108,568,777 - 108,568,861 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,568,777 - 108,568,861 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,471,108 - 108,471,192 (+)NCBIGRCm37mm9NCBIm37
Celera9108,180,018 - 108,180,102 (+)NCBICelera
Cytogenetic Map9F2NCBI
MIR425
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,020,148 - 49,020,234 (-)EnsemblGRCh38hg38GRCh38
GRCh38349,020,148 - 49,020,234 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,057,581 - 49,057,667 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,032,584 - 49,032,670 (-)NCBINCBI36hg18NCBI36
Celera349,014,304 - 49,014,390 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,115,446 - 49,115,532 (-)NCBIHuRef
CHM1_1349,010,142 - 49,010,228 (-)NCBICHM1_1
Mir425
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08117,354,821 - 117,354,903 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,354,821 - 117,354,903 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,699,324 - 116,699,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,560,329 - 108,560,411 (+)NCBICelera
Cytogenetic Map8q32NCBI
MIR425
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2040,144,606 - 40,144,683 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12040,144,613 - 40,144,675 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
MIR425
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,654,994 - 31,655,073 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,654,994 - 31,655,073 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,898,111 - 34,898,190 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
AV253134  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,568,986 - 108,569,125UniSTSGRCm38
MGSCv379108,471,317 - 108,471,456UniSTSGRCm37
Celera9108,180,227 - 108,180,366UniSTS
Cytogenetic Map9F2UniSTS
Whitehead/MRC_RH91110.14UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Tmx4mmu-miR-425-5pMirtarbaseexternal_infoSequencingFunctional MTI (Weak)19536157
Abca1mmu-miR-425-5pTarbaseexternal_infoSequencingPOSITIVE

Predicted Targets
Summary Value
Count of predictions:9410
Count of gene targets:5032
Count of transcripts:7768
Interacting mature miRNAs:mmu-miR-425-3p, mmu-miR-425-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_029947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CT010508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000083645
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9108,568,777 - 108,568,861 (+)Ensembl
RefSeq Acc Id: NR_029947
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,445,976 - 108,446,060 (+)NCBI
GRCm389108,568,777 - 108,568,861 (+)ENTREZGENE
MGSCv379108,471,108 - 108,471,192 (+)RGD
Celera9108,180,018 - 108,180,102 (+)RGD
cM Map9 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619401 AgrOrtholog
Ensembl Genes ENSMUSG00000065579 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083645 ENTREZGENE
MGD MGI:3619401 ENTREZGENE
miRBase MI0001447 ENTREZGENE
NCBI Gene 723864 ENTREZGENE
PhenoGen Mir425 PhenoGen
RNAcentral URS00002895D7 RNACentral
  URS000048BA36 RNACentral
  URS00006EF746 RNACentral