Spata22 (spermatogenesis associated 22) - Rat Genome Database

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Gene: Spata22 (spermatogenesis associated 22) Mus musculus
Analyze
Symbol: Spata22
Name: spermatogenesis associated 22
RGD ID: 1607688
MGI Page MGI
Description: Acts upstream of or within several processes, including fertilization; meiosis I cell cycle process; and regulation of meiotic cell cycle. Located in chromosome. Is expressed in ileum; male reproductive gland or organ; and ovary. Orthologous to human SPATA22 (spermatogenesis associated 22).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm882; spermatogenesis-associated protein 22
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,217,416 - 73,237,447 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,220,567 - 73,236,870 (+)EnsemblGRCm39 Ensembl
GRCm381173,326,560 - 73,346,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,329,741 - 73,346,044 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,143,243 - 73,159,546 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,143,243 - 73,159,546 (+)NCBIMGSCv36mm8
Celera1180,866,666 - 80,882,981 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21677750   PMID:21873635   PMID:22011390   PMID:24194600   PMID:24240703   PMID:26742488   PMID:27626380   PMID:27739607   PMID:28297563   PMID:28453612   PMID:29878059  
PMID:30272023   PMID:30746471   PMID:30760716   PMID:31358751   PMID:32345962   PMID:32388826   PMID:32845237   PMID:35489071  


Genomics

Comparative Map Data
Spata22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,217,416 - 73,237,447 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,220,567 - 73,236,870 (+)EnsemblGRCm39 Ensembl
GRCm381173,326,560 - 73,346,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,329,741 - 73,346,044 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,143,243 - 73,159,546 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,143,243 - 73,159,546 (+)NCBIMGSCv36mm8
Celera1180,866,666 - 80,882,981 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.29NCBI
SPATA22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38173,440,019 - 3,513,858 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl173,440,019 - 3,513,852 (-)EnsemblGRCh38hg38GRCh38
GRCh37173,343,313 - 3,417,152 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36173,290,063 - 3,321,790 (-)NCBINCBI36Build 36hg18NCBI36
Celera173,357,027 - 3,388,867 (-)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef173,235,800 - 3,267,078 (-)NCBIHuRef
CHM1_1173,352,921 - 3,385,561 (-)NCBICHM1_1
T2T-CHM13v2.0173,328,922 - 3,402,768 (-)NCBIT2T-CHM13v2.0
Spata22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81058,443,736 - 58,461,578 (+)NCBIGRCr8
mRatBN7.21057,945,272 - 57,963,081 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1057,932,187 - 57,963,081 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1062,603,027 - 62,619,281 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01062,091,496 - 62,107,761 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01057,590,631 - 57,606,895 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01059,893,064 - 59,910,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1059,879,850 - 59,911,051 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01059,632,294 - 59,649,996 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41060,205,533 - 60,221,778 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1057,069,677 - 57,085,922 (+)NCBICelera
Cytogenetic Map10q24NCBI
Spata22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546713,306,496 - 13,325,300 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546713,304,314 - 13,325,228 (+)NCBIChiLan1.0ChiLan1.0
SPATA22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21910,711,834 - 11,123,382 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11712,678,198 - 13,089,813 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0173,120,296 - 3,532,343 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1173,489,143 - 3,560,652 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl173,489,143 - 3,560,654 (-)Ensemblpanpan1.1panPan2
SPATA22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,322,817 - 47,338,202 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl947,322,820 - 47,338,108 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,485,645 - 46,501,031 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,167,528 - 48,182,913 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,167,531 - 48,182,819 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1946,939,961 - 46,955,386 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,231,340 - 47,246,722 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,288,803 - 47,304,188 (-)NCBIUU_Cfam_GSD_1.0
Spata22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560255,701,702 - 55,733,760 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936677167,324 - 196,188 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936677167,324 - 197,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPATA22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,576,835 - 49,608,237 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11249,573,050 - 49,609,232 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21251,416,337 - 51,416,682 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPATA22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1162,952,912 - 2,977,812 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl162,952,968 - 2,975,704 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605918,874,897 - 18,941,652 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spata22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247866,139,452 - 6,164,535 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Spata22
8 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:766
Count of miRNA genes:468
Interacting mature miRNAs:553
Transcripts:ENSMUST00000092926, ENSMUST00000117445
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000092926   ⟹   ENSMUSP00000090602
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,220,567 - 73,236,870 (+)Ensembl
GRCm38.p6 Ensembl1173,329,741 - 73,346,044 (+)Ensembl
RefSeq Acc Id: NM_001045531   ⟹   NP_001038996
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391173,220,567 - 73,236,870 (+)NCBI
GRCm381173,329,741 - 73,346,044 (+)NCBI
MGSCv371173,143,243 - 73,159,546 (+)RGD
Celera1180,866,666 - 80,882,981 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011249095   ⟹   XP_011247397
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391173,217,471 - 73,237,447 (+)NCBI
GRCm381173,326,560 - 73,346,434 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011249096   ⟹   XP_011247398
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391173,217,761 - 73,237,447 (+)NCBI
GRCm381173,326,741 - 73,346,592 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011249097   ⟹   XP_011247399
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391173,217,416 - 73,237,447 (+)NCBI
GRCm381173,326,560 - 73,346,434 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001038996   ⟸   NM_001045531
- UniProtKB: Q5SV06 (UniProtKB/Swiss-Prot),   B2KFD7 (UniProtKB/TrEMBL),   B0QZP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247397   ⟸   XM_011249095
- Peptide Label: isoform X1
- UniProtKB: Q5SV06 (UniProtKB/Swiss-Prot),   B2KFD7 (UniProtKB/TrEMBL),   B0QZP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247399   ⟸   XM_011249097
- Peptide Label: isoform X1
- UniProtKB: Q5SV06 (UniProtKB/Swiss-Prot),   B2KFD7 (UniProtKB/TrEMBL),   B0QZP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247398   ⟸   XM_011249096
- Peptide Label: isoform X1
- UniProtKB: Q5SV06 (UniProtKB/Swiss-Prot),   B2KFD7 (UniProtKB/TrEMBL),   B0QZP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000090602   ⟸   ENSMUST00000092926

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5SV06-F1-model_v2 AlphaFold Q5SV06 1-358 view protein structure

Promoters
RGD ID:6822206
Promoter ID:MM_KWN:8371
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:ENSMUST00000117445,   NM_001045531
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361173,142,761 - 73,143,261 (+)MPROMDB
RGD ID:8675490
Promoter ID:EPDNEW_M15776
Type:multiple initiation site
Name:Spata22_1
Description:Mus musculus spermatogenesis associated 22 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381173,329,743 - 73,329,803EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685728 AgrOrtholog
Ensembl Genes ENSMUSG00000069825 UniProtKB/TrEMBL
  ENSMUSG00000112920 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000092926 ENTREZGENE
  ENSMUST00000092926.11 UniProtKB/Swiss-Prot
  ENSMUST00000117445.2 UniProtKB/TrEMBL
InterPro Spata22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:380709 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2685728 ENTREZGENE
NCBI Gene 380709 ENTREZGENE
PANTHER PTHR35258 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPERMATOGENESIS-ASSOCIATED PROTEIN 22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Spata22 PhenoGen
UniProt B0QZP0 ENTREZGENE, UniProtKB/TrEMBL
  B2KFD7 ENTREZGENE, UniProtKB/TrEMBL
  Q5SV06 ENTREZGENE, UniProtKB/Swiss-Prot