Mirlet7f-2 (microRNA let7f-2) - Rat Genome Database
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Gene: Mirlet7f-2 (microRNA let7f-2) Mus musculus
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Symbol: Mirlet7f-2
Name: microRNA let7f-2
RGD ID: 1607635
MGI Page MGI
Description: Involved in several processes, including BMP signaling pathway; cellular response to amino acid stimulus; and long-term synaptic potentiation. Localizes to RISC complex. Is expressed in embryo. Orthologous to human MIRLET7F2 (microRNA let-7f-2).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: let-7f-2; Mirlet7f2; Mirnle; Mirnlet7f2
RGD Orthologs
Human
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X150,695,342 - 150,695,424 (+)NCBIGRCm39mm39
GRCm38X151,912,346 - 151,912,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX151,912,346 - 151,912,428 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X148,346,889 - 148,346,971 (+)NCBIGRCm37mm9NCBIm37
CeleraX132,518,047 - 132,518,129 (-)NCBICelera
Cytogenetic MapXF3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IDA)

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12007417   PMID:15538371   PMID:16369549   PMID:16381832   PMID:16766679   PMID:16882971   PMID:17369397   PMID:17604727   PMID:19520079   PMID:19949436   PMID:20215419   PMID:20413612  
PMID:20548288   PMID:20668074   PMID:21037258   PMID:21267068   PMID:21822254   PMID:22895573   PMID:23185045   PMID:23200853   PMID:23895693   PMID:25295787   PMID:25751060   PMID:25858512  
PMID:26139524   PMID:30635573   PMID:31354981   PMID:31653921   PMID:31942002  


Genomics

Comparative Map Data
Mirlet7f-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X150,695,342 - 150,695,424 (+)NCBIGRCm39mm39
GRCm38X151,912,346 - 151,912,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX151,912,346 - 151,912,428 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X148,346,889 - 148,346,971 (+)NCBIGRCm37mm9NCBIm37
CeleraX132,518,047 - 132,518,129 (-)NCBICelera
Cytogenetic MapXF3NCBI
MIRLET7F2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX53,557,192 - 53,557,274 (-)EnsemblGRCh38hg38GRCh38
GRCh38X53,557,192 - 53,557,274 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X53,584,153 - 53,584,235 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X53,600,877 - 53,600,959 (-)NCBINCBI36hg18NCBI36
CeleraX57,415,722 - 57,415,804 (-)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX50,640,113 - 50,640,195 (-)NCBIHuRef
CHM1_1X53,575,129 - 53,575,211 (-)NCBICHM1_1
Mirlet7f2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X20,980,632 - 20,980,714 (+)NCBI
Rnor_6.0 EnsemblX21,583,272 - 21,583,354 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X21,583,272 - 21,583,354 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X21,868,509 - 21,868,591 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX21,261,812 - 21,261,894 (+)NCBICelera
Cytogenetic MapXq13NCBI
MIRLET7F-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX46,303,245 - 46,303,327 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X46,303,245 - 46,303,327 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X51,801,728 - 51,801,810 (-)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX103012242163975945Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX122083468161430042Mouse
25314309Syncl5_msynaptonemal complex length 5 (mouse)X123000000153800000Mouse
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX126902153160902273Mouse
13824981Svwq2_mseminal vesicle weight QTL 2 (mouse)X130000000155000000Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX134639291166515599Mouse
1301276Tswt_mtestis weight (mouse)Not determinedX139475662152006342Mouse
1302000Pgia25_mproteoglycan induced arthritis 2 (mouse)Not determinedX145691384171031299Mouse
10401118Pgia39_mproteoglycan induced arthritis 39 (mouse)Not determinedX145691384171031299Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Pak1mmu-let-7f-5pOncomiRDBexternal_infoNANA23339187
Hmga2mmu-let-7f-5pOncomiRDBexternal_infoNANA23318420
Mycnmmu-let-7f-5pOncomiRDBexternal_infoNANA23042116
Has2mmu-let-7f-5pOncomiRDBexternal_infoNANA22871741
Ezh2mmu-let-7f-5pOncomiRDBexternal_infoNANA22442719
Cyp19a1mmu-let-7f-5pOncomiRDBexternal_infoNANA22407818
Myh9mmu-let-7f-5pOncomiRDBexternal_infoNANA21533124
Fasmmu-let-7f-5pOncomiRDBexternal_infoNANA21530489
Lin28ammu-let-7f-5pOncomiRDBexternal_infoNANA21045151
Esr1mmu-let-7f-5pOncomiRDBexternal_infoNANA20535543
Nol3mmu-let-7f-5pOncomiRDBexternal_infoNANA20525879
Klk10mmu-let-7f-5pOncomiRDBexternal_infoNANA20354523
Klk10mmu-let-7f-5pOncomiRDBexternal_infoNANA20180642
Il6mmu-let-7f-5pOncomiRDBexternal_infoNANA19878981
Hmga2mmu-let-7f-5pOncomiRDBexternal_infoNANA19153603
Dicer1mmu-let-7f-5pOncomiRDBexternal_infoNANA18700235
Hmga2mmu-let-7f-5pOncomiRDBexternal_infoNANA18403645
Hmga2mmu-let-7f-5pOncomiRDBexternal_infoNANA17600087
Hmga2mmu-let-7f-5pOncomiRDBexternal_infoNANA17437991
Hmga2mmu-let-7f-5pOncomiRDBexternal_infoNANA17322030
Krasmmu-let-7f-5pOncomiRDBexternal_infoNANA15766527

Predicted Targets
Summary Value
Count of predictions:25216
Count of gene targets:9949
Count of transcripts:16421
Interacting mature miRNAs:mmu-let-7f-2-3p, mmu-let-7f-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083668
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 EnsemblX151,912,346 - 151,912,428 (+)Ensembl
RefSeq Acc Id: NR_029732
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X150,695,342 - 150,695,424 (+)NCBI
GRCm38X151,912,346 - 151,912,428 (+)ENTREZGENE
MGSCv37X148,346,889 - 148,346,971 (+)RGD
CeleraX132,518,047 - 132,518,129 (-)RGD
cM MapX ENTREZGENE
Sequence:
Promoters
RGD ID:13681636
Promoter ID:EPDNEW_M24967
Type:single initiation site
Name:Mirlet7f-2_1
Description:Mus musculus microRNA let7f-2 (Mirlet7f-2), microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X151,912,425 - 151,912,485EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676799 AgrOrtholog
Ensembl Genes ENSMUSG00000065602 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083668 ENTREZGENE
MGD MGI:2676799 ENTREZGENE
miRBase MI0000563 ENTREZGENE
NCBI Gene 387253 ENTREZGENE
PhenoGen Mirlet7f-2 PhenoGen
RNAcentral URS00003B7674 RNACentral
  URS00004747E1 RNACentral
  URS000075D19A RNACentral