Mir7-1 (microRNA 7-1) - Rat Genome Database

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Gene: Mir7-1 (microRNA 7-1) Mus musculus
Analyze
Symbol: Mir7-1
Name: microRNA 7-1
RGD ID: 1607619
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to lipid; columnar/cuboidal epithelial cell differentiation; and negative regulation of macromolecule biosynthetic process. Part of RISC complex. Is expressed in several structures, including brain; eye; foregut-midgut junction; genitourinary system; and hemolymphoid system gland. Orthologous to human MIR7-1 (microRNA 7-1) and MIR7-2 (microRNA 7-2).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: Mir; miR-; mir-7a-1; miR-7a1; Mir7a1; Mirn; Mirn7-1; mmu-miR-; mmu-mir-7; mmu-mir-7-1; mmu-miR-7a1
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391358,540,593 - 58,540,700 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1358,540,593 - 58,540,700 (-)EnsemblGRCm39 Ensembl
GRCm381358,392,779 - 58,392,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1358,392,779 - 58,392,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv371358,494,140 - 58,494,247 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1359,455,142 - 59,455,249 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1331.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12624257   PMID:15538371   PMID:15634332   PMID:16369549   PMID:16381832   PMID:17369397   PMID:17597072   PMID:17604727   PMID:17936263   PMID:19628698   PMID:20106983   PMID:20215419  
PMID:20230785   PMID:20413612   PMID:20439489   PMID:21037258   PMID:21247879   PMID:21267068   PMID:21307095   PMID:21822254   PMID:21993888   PMID:22139078   PMID:22144232   PMID:22186137  
PMID:22442111   PMID:22661094   PMID:22696677   PMID:22729175   PMID:22764048   PMID:22775435   PMID:23185045   PMID:23223022   PMID:23390484   PMID:23446348   PMID:23940725   PMID:24205035  
PMID:24789908   PMID:24813889   PMID:24925797   PMID:25048085   PMID:25334070   PMID:25858512   PMID:26122050   PMID:26211738   PMID:26572867   PMID:26676570   PMID:26998750   PMID:27084336  
PMID:27286445   PMID:27384152   PMID:27707753   PMID:28218624   PMID:28353063   PMID:28798046   PMID:29663842   PMID:29887379   PMID:30538177   PMID:30578296   PMID:30982661   PMID:31044367  
PMID:31166710   PMID:31494796   PMID:31756561   PMID:31786325   PMID:32539181   PMID:33029099   PMID:33125780   PMID:33452745   PMID:33748999   PMID:34399097   PMID:34697773   PMID:34713362  
PMID:35038382   PMID:35317842   PMID:35652338   PMID:36175420   PMID:36883209   PMID:37086967   PMID:37094666   PMID:37755574  


Genomics

Comparative Map Data
Mir7-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391358,540,593 - 58,540,700 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1358,540,593 - 58,540,700 (-)EnsemblGRCm39 Ensembl
GRCm381358,392,779 - 58,392,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1358,392,779 - 58,392,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv371358,494,140 - 58,494,247 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1359,455,142 - 59,455,249 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1331.04NCBI
MIR7-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38983,969,748 - 83,969,857 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl983,969,748 - 83,969,857 (-)EnsemblGRCh38hg38GRCh38
GRCh37986,584,663 - 86,584,772 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36985,774,482 - 85,774,591 (-)NCBINCBI36Build 36hg18NCBI36
Celera957,155,676 - 57,155,785 (-)NCBICelera
Cytogenetic Map9q21.32NCBI
HuRef956,410,296 - 56,410,405 (-)NCBIHuRef
CHM1_1986,731,260 - 86,731,369 (-)NCBICHM1_1
T2T-CHM13v2.0996,120,029 - 96,120,138 (-)NCBIT2T-CHM13v2.0
Mir7-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,278,692 - 6,278,788 (+)NCBIGRCr8
mRatBN7.2176,273,264 - 6,273,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,273,264 - 6,273,360 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx176,295,979 - 6,296,075 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0177,829,327 - 7,829,423 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,292,351 - 6,292,447 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0176,675,016 - 6,675,112 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl176,675,016 - 6,675,112 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0178,879,389 - 8,879,485 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera176,382,983 - 6,383,079 (+)NCBICelera
Cytogenetic Map17p14NCBI
MIR7-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1175,509,765 - 75,509,828 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl175,509,743 - 75,509,851 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,159,656 - 76,159,719 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0175,811,059 - 75,811,122 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl175,811,037 - 75,811,145 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1175,625,031 - 75,625,094 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0175,387,843 - 75,387,906 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,090,715 - 76,090,778 (+)NCBIUU_Cfam_GSD_1.0
MIR7-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1030,986,180 - 30,986,288 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11030,986,180 - 30,986,288 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21035,113,341 - 35,113,449 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir7-1
8 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:12314
Count of gene targets:5626
Count of transcripts:8741
Interacting mature miRNAs:mmu-miR-7a-1-3p
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2583652959836529Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132791846961918560Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132821044262210544Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132821737962217515Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132821737962217515Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083500
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,540,593 - 58,540,700 (-)Ensembl
GRCm38.p6 Ensembl1358,392,779 - 58,392,886 (-)Ensembl
RefSeq Acc Id: NR_029825
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,540,593 - 58,540,700 (-)NCBI
GRCm381358,392,779 - 58,392,886 (-)ENTREZGENE
MGSCv371358,494,140 - 58,494,247 (-)RGD
Celera1359,455,142 - 59,455,249 (-)RGD
cM Map13 ENTREZGENE
Sequence:
Promoters
RGD ID:8680532
Promoter ID:EPDNEW_M18297
Type:single initiation site
Name:Mir7-1_1
Description:Mus musculus microRNA 7-1 (Mir7-1), microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381358,392,797 - 58,392,857EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619436 AgrOrtholog
Ensembl Genes ENSMUSG00000065434 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083500 ENTREZGENE
MGD MGI:3619436 ENTREZGENE
miRBase MI0000728 ENTREZGENE
NCBI Gene 723902 ENTREZGENE
PhenoGen Mir7-1 PhenoGen
RNAcentral URS000028D811 RNACentral
  URS0000591950 RNACentral
  URS000075EF96 RNACentral