Mir181b-2 (microRNA 181b-2) - Rat Genome Database

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Gene: Mir181b-2 (microRNA 181b-2) Mus musculus
Analyze
Symbol: Mir181b-2
Name: microRNA 181b-2
RGD ID: 1607618
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to lipid; long-term synaptic potentiation; and regulation of gene expression. Is expressed in cerebral cortex and telencephalon. Orthologous to human MIR181B2 (microRNA 181b-2).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-181b; mir-181b-2; Mirn181; Mirn181b-2
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,743,842 - 38,743,930 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl238,743,842 - 38,743,930 (+)EnsemblGRCm39 Ensembl
GRCm38238,853,830 - 38,853,918 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,853,830 - 38,853,918 (+)EnsemblGRCm38mm10GRCm38
MGSCv37238,709,350 - 38,709,438 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera240,577,942 - 40,578,030 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12624257   PMID:15538371   PMID:16381832   PMID:16766679   PMID:17369397   PMID:17604727   PMID:18282110   PMID:18452032   PMID:18762567   PMID:19806666   PMID:20215419   PMID:20413612  
PMID:21037258   PMID:21993888   PMID:22622040   PMID:23262291   PMID:23622242   PMID:23650073   PMID:24084690   PMID:24967703   PMID:25858512   PMID:27089939   PMID:30578296   PMID:30627917  
PMID:30860638   PMID:30979712   PMID:31003188   PMID:31189717   PMID:31682635   PMID:32066445   PMID:34469488   PMID:35593587   PMID:36195241   PMID:37231890   PMID:37421280  


Genomics

Comparative Map Data
Mir181b-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,743,842 - 38,743,930 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl238,743,842 - 38,743,930 (+)EnsemblGRCm39 Ensembl
GRCm38238,853,830 - 38,853,918 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,853,830 - 38,853,918 (+)EnsemblGRCm38mm10GRCm38
MGSCv37238,709,350 - 38,709,438 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera240,577,942 - 40,578,030 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
MIR181B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389124,693,710 - 124,693,798 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9124,693,710 - 124,693,798 (+)EnsemblGRCh38hg38GRCh38
GRCh379127,455,989 - 127,456,077 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369126,495,809 - 126,495,897 (+)NCBINCBI36Build 36hg18NCBI36
Celera998,103,875 - 98,103,963 (+)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef997,068,713 - 97,068,801 (+)NCBIHuRef
CHM1_19127,604,858 - 127,604,946 (+)NCBICHM1_1
T2T-CHM13v2.09136,891,958 - 136,892,046 (+)NCBIT2T-CHM13v2.0
Mir181b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8343,026,666 - 43,026,753 (+)NCBIGRCr8
mRatBN7.2322,616,948 - 22,617,035 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl322,616,948 - 22,617,035 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx326,085,666 - 26,085,753 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0334,670,659 - 34,670,746 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0332,483,204 - 32,483,291 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0323,151,455 - 23,151,542 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl323,151,455 - 23,151,542 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,375,872 - 28,375,959 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera321,050,405 - 21,050,492 (+)NCBICelera
Cytogenetic Map3q12NCBI
MIR181B-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1958,301,314 - 58,301,373 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl958,301,300 - 58,301,388 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha957,499,947 - 57,500,006 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0959,221,648 - 59,221,707 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl959,221,634 - 59,221,722 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1957,980,488 - 57,980,547 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0958,296,855 - 58,296,914 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0958,387,339 - 58,387,398 (-)NCBIUU_Cfam_GSD_1.0
MIR181B-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1265,499,108 - 265,499,196 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11265,499,111 - 265,499,196 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21299,324,014 - 299,324,099 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir181b-2
1 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:20994
Count of gene targets:8477
Count of transcripts:13883
Interacting mature miRNAs:mmu-miR-181b-2-3p, mmu-miR-181b-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
13464253Ifvrq1_minfluenza virus resistance QTL 1 (mouse)23303449252034492Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3579732469797406Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3579732469797406Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3579732469797406Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23599167971609412Mouse
10449151Hdl8_mhigh density lipoprotein (HDL) level 8 (mouse)23812972567072607Mouse
10449150Pvldlc1_mplasma VLDL-cholesterol 1 (mouse)23812972567072607Mouse
10449145Lanq1_mlanosterol level QTL 1 (mouse)23812972567072607Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083644
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl238,743,842 - 38,743,930 (+)Ensembl
GRCm38.p6 Ensembl238,853,830 - 38,853,918 (+)Ensembl
RefSeq Acc Id: NR_029904
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39238,743,842 - 38,743,930 (+)NCBI
GRCm38238,853,830 - 38,853,918 (+)ENTREZGENE
MGSCv37238,709,350 - 38,709,438 (+)RGD
Celera240,577,942 - 40,578,030 (+)RGD
cM Map2 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3618736 AgrOrtholog
Ensembl Genes ENSMUSG00000065578 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083644 ENTREZGENE
MGD MGI:3618736 ENTREZGENE
miRBase MI0000823 ENTREZGENE
NCBI Gene 723903 ENTREZGENE
PhenoGen Mir181b-2 PhenoGen
RNAcentral URS000009F727 RNACentral
  URS0000574E81 RNACentral
  URS000075B3B1 RNACentral