Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{$index + 1}}. {{ watchedTerm.term }} ({{watchedTerm.accId}})
{{gene.symbol}}: {{ gene.description }}
Save what matters to you
{{ loginError }}
Sign in with your RGD account
Gene: Mirlet7c-2 (microRNA let7c-2) Mus musculus
Analyze
Symbol:
Mirlet7c-2
Name:
microRNA let7c-2
RGD ID:
1607558
MGI Page
MGI
Description:
Involved in embryo implantation; long-term synaptic potentiation; and negative regulation of gene expression. Localizes to RISC complex. Is expressed in brain; embryo; and upper jaw incisor. Orthologous to human MIRLET7A3 (microRNA let-7a-3).
Type:
ncrna
RefSeq Status:
PROVISIONAL
Also known as:
let-7c-2; Mirnlet; Mirnlet7c-2
RGD Orthologs
Alliance Genes
More Info
more info ...
More Info
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 15 85,590,804 - 85,590,898 (+) NCBI GRCm39 mm39 GRCm38 15 85,706,603 - 85,706,697 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 15 85,706,603 - 85,706,697 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 15 85,537,033 - 85,537,127 (+) NCBI GRCm37 mm9 NCBIm37 Celera 15 87,839,385 - 87,839,479 (+) NCBI Celera Cytogenetic Map 15 E2 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Disease Annotations - ClinVar
References
Additional References at PubMed
Genomics
QTLs in Region (GRCm38)
27226734 Tibmd5_m tibia midshaft diameter 5, 10 week (mouse) 15 6100000 86800000 Mouse 26884442 Sklq6_m skull length QTL 6, 5 week (mouse) 15 6100000 100900000 Mouse 1357526 Hyplip2_m hyperlipidemia 2 (mouse) Not determined 15 12402117 102988123 Mouse 26884425 Cvht2_m cranial vault height 2, 5 week (mouse) 15 28800000 102100000 Mouse 1558985 Eae32_m experimental allergic encephalomyelitis susceptibility 32 (mouse) Not determined 15 32578270 103517472 Mouse 27226729 Tibmd2_m tibia midshaft diameter 2, 5 week (mouse) 15 38000000 86800000 Mouse 26884402 Cvht9_m cranial vault height 9, 16 week (mouse) 15 42300000 95600000 Mouse 1300644 Fob3_m F-line obesity QTL 3 (mouse) 11.3 Not determined 15 44144438 89377036 Mouse 26884397 Humsd5_m humerus midshaft diameter 5, 10 week (mouse) 15 48500000 98500000 Mouse 26884399 Humsd1_m humerus midshaft diameter 1, 5 week (mouse) 15 48500000 101800000 Mouse 10412067 Pain2_m pain 2 (mouse) Not determined 15 51773490 85773777 Mouse 1302080 Szs13_m seizure susceptibility 13 (mouse) Not determined 15 51813983 85822600 Mouse 1301708 Cocrb14_m cocaine related behavior 14 (mouse) Not determined 15 51934666 85934802 Mouse 38501067 Tip3_m tuberculosis immunophenotype 3, IFN-g level (mouse) 15 53700000 89700000 Mouse 13504731 Cath5_m carotid atherosclerosis 5 (mouse) 15 54917280 88917280 Mouse 1302074 Bmd4_m bone mineral density 4 (mouse) Not determined 15 56323312 103517472 Mouse 27095936 Ulnl4_m ulna length 4, 5 week (mouse) 15 56900000 87800000 Mouse 1300800 Ses3_m salmonella enteritidis susceptibility 3 (mouse) Not determined 15 57245156 91245304 Mouse 1357407 Pfat4_m predicted fat percentage 4 (mouse) 8.6 Body fat amount predicted fat percentage 15 57245156 91245304 Mouse 12880420 V25Dq8_m vitamin D inactive form serum level QTL 8 (mouse) 15 61700000 95700000 Mouse 1301601 Faq9_m fluctuating asymmetry QTL 9 (mouse) Not determined 15 63279702 97279794 Mouse 1302197 Bhr2_m bronchial hyperresponsiveness 2 (mouse) Not determined 15 64434485 103517472 Mouse 4141135 Cia35_m collagen induced arthritis 35 (mouse) Not determined 15 64927625 98927745 Mouse 1301119 Drb7_m dopamine receptor binding 7 (mouse) Not determined 15 65452377 99456827 Mouse 1301171 Brm2_m brachyury modifier 2 (mouse) Not determined 15 65641175 99641298 Mouse 4141921 Pstc3_m periosteal circumference 3 (mouse) Not determined 15 67386497 101386646 Mouse 1300627 Sluc26_m susceptibility to lung cancer 26 (mouse) Not determined 15 70461452 104043685 Mouse 1300726 Pitm4_m prion incubation time 4 (mouse) Not determined 15 70465070 104043685 Mouse 1300648 Dbsty4_m diabesity 4 (mouse) Not determined 15 70465070 104043685 Mouse 14747011 Mancz13_m mandible centroid size 13 (mouse) 15 72498466 104043685 Mouse 12791003 Aath8_m aortic arch atherosclerosis 8 (mouse) 15 73545941 104043685 Mouse 1301472 Pain1_m pain 1 (mouse) Not determined 15 75448997 90928982 Mouse 1300851 Heal4_m wound healing/regeneration 4 (mouse) Not determined 15 77629711 104043685 Mouse 4142060 W3q6_m weight 3 weeks QTL 6 (mouse) Not determined 78716903 102993272 Mouse 1357894 Epfpq3_m epididymal fat percentage QTL 3 (mouse) Not determined 15 78716903 102993272 Mouse 14928306 Manh79_m mandible shape 79 (mouse) 15 78949676 104043685 Mouse 12880411 V125Dq11_m vitamin D active form serum level QTL 11 (mouse) 15 79000000 104043685 Mouse 10402490 Dipa5_m drug induced psychomotor activation 5 (mouse) Not determined 15 79265530 104043685 Mouse 4141897 Imrfq2_m immune response to Factor IX QTL 2 (mouse) Not determined 80011059 104043685 Mouse 1301284 Cosz3_m cocaine seizure 3 (mouse) Not determined 15 80415753 104043685 Mouse 4141902 Cia37_m collagen induced arthritis 37 (mouse) Not determined 15 80987052 104043685 Mouse 1300974 Pgia9_m proteoglycan induced arthritis 9 (mouse) Not determined 15 80987052 104043685 Mouse 4141511 Gdcr1_m glycerolphosphate dehydrogenase regulator 1 (mouse) Not determined 82717593 104043685 Mouse 11532732 Pitm5_m prion incubation time 5 (mouse) 15 83079860 87170187 Mouse
miRNA Target Status
Confirmed Targets
Sall4 mmu-let-7c-5p Mirtarbase external_info Luciferase reporter assay//Microarray//qRT-PCR//We Functional MTI 20054295 Myc mmu-let-7c-5p Mirtarbase external_info Luciferase reporter assay//Microarray//qRT-PCR;Oth Functional MTI 17438130 Myc mmu-let-7c-5p Mirtarbase external_info Microarray//qRT-PCR//Western blot Functional MTI 20054295 Myc mmu-let-7c-5p Tarbase external_info qPCR POSITIVE Pak1 mmu-let-7c-5p OncomiRDB external_info NA NA 23339187 Hmga2 mmu-let-7c-5p OncomiRDB external_info NA NA 23318420 Mycn mmu-let-7c-5p OncomiRDB external_info NA NA 23042116 Pbx2 mmu-let-7c-5p OncomiRDB external_info NA NA 22964640 Has2 mmu-let-7c-5p OncomiRDB external_info NA NA 22871741 Ezh2 mmu-let-7c-5p OncomiRDB external_info NA NA 22442719 Kras mmu-let-7c-5p OncomiRDB external_info NA NA 21984339 Fas mmu-let-7c-5p OncomiRDB external_info NA NA 21530489 Socs1 mmu-let-7c-5p OncomiRDB external_info NA NA 21352471 Lin28a mmu-let-7c-5p OncomiRDB external_info NA NA 21045151 Esr1 mmu-let-7c-5p OncomiRDB external_info NA NA 20535543 Nol3 mmu-let-7c-5p OncomiRDB external_info NA NA 20525879 Bcl2l1 mmu-let-7c-5p OncomiRDB external_info NA NA 20347499 Il6 mmu-let-7c-5p OncomiRDB external_info NA NA 19878981 Hmga2 mmu-let-7c-5p OncomiRDB external_info NA NA 19153603 Dicer1 mmu-let-7c-5p OncomiRDB external_info NA NA 18700235 Hmga2 mmu-let-7c-5p OncomiRDB external_info NA NA 18403645 Hmga2 mmu-let-7c-5p OncomiRDB external_info NA NA 17600087 Hmga2 mmu-let-7c-5p OncomiRDB external_info NA NA 17437991 Hmga2 mmu-let-7c-5p OncomiRDB external_info NA NA 17322030 Kras mmu-let-7c-5p OncomiRDB external_info NA NA 15766527
Predicted Targets
Count of predictions: 29148 Count of gene targets: 10642 Count of transcripts: 17888 Interacting mature miRNAs: mmu-let-7c-2-3p, mmu-let-7c-5p Prediction methods: Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan Result types: miRGate_prediction