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Gene: DESI1 (desumoylating isopeptidase 1) Homo sapiens
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Symbol: DESI1
Name: desumoylating isopeptidase 1
Description: Exhibits importin-alpha family protein binding activity. Involved in protein export from nucleus and regulation of proteasomal ubiquitin-dependent protein catabolic process. Localizes to cytosol and protein-containing complex; INTERACTS WITH 17beta-estradiol; all-trans-retinoic acid; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D15Wsu75e; DeSI-1; DESI2; desumoylating isopeptidase 2; DJ347H13.4; FAM152B; family with sequence similarity 152, member B; MGC138384; polyubiquitinated substrate transporter; POST; PPPDE peptidase domain containing 2; PPPDE peptidase domain-containing protein 2; PPPDE2
Orthologs:
Mus musculus (house mouse) : Desi1 (desumoylating isopeptidase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Desi1 (desumoylating isopeptidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Desi1 (desumoylating isopeptidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DESI1 (desumoylating isopeptidase 1)
Canis lupus familiaris (dog) : DESI1 (desumoylating isopeptidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Desi1 (desumoylating isopeptidase 1)
Sus scrofa (pig) : DESI1 (desumoylating isopeptidase 1)
Chlorocebus sabaeus (African green monkey) : DESI1 (desumoylating isopeptidase 1)
Heterocephalus glaber (naked mole-rat) : Desi1 (desumoylating isopeptidase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,598,028 - 41,621,043 (-)EnsemblGRCh38hg38GRCh38
GRCh382241,598,028 - 41,621,077 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,994,032 - 42,017,079 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,326,882 - 40,346,862 (-)NCBINCBI36hg18NCBI36
Celera2225,803,363 - 25,823,345 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,959,686 - 24,982,663 (-)NCBIHuRef
CHM1_12241,954,084 - 41,977,109 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DESI1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1607044
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.