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Gene: RTN4R (reticulon 4 receptor) Homo sapiens
Symbol: RTN4R
Name: reticulon 4 receptor
Description: Exhibits ganglioside GM1 binding activity and ganglioside GT1b binding activity. Involved in positive regulation of Rho protein signal transduction. Localizes to anchored component of external side of plasma membrane and endoplasmic reticulum. Implicated in schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: NGR; nogo receptor; Nogo-66 receptor; NOGOR; reticulon-4 receptor; UNQ330/PRO526
Mus musculus (house mouse) : Rtn4r (reticulon 4 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rtn4r (reticulon 4 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rtn4r (reticulon 4 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : RTN4R (reticulon 4 receptor)
Canis lupus familiaris (dog) : RTN4R (reticulon 4 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rtn4r (reticulon 4 receptor)
Sus scrofa (pig) : RTN4R (reticulon 4 receptor)
Chlorocebus sabaeus (African green monkey) : RTN4R (reticulon 4 receptor)
Heterocephalus glaber (naked mole-rat) : Rtn4r (reticulon 4 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2220,241,415 - 20,283,246 (-)EnsemblGRCh38hg38GRCh38
GRCh382220,241,415 - 20,268,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372220,228,938 - 20,255,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,608,938 - 18,635,816 (-)NCBINCBI36hg18NCBI36
Celera224,079,624 - 4,107,575 (-)NCBI
Cytogenetic Map22q11.21NCBI
HuRef223,848,286 - 3,849,983 (-)NCBIHuRef
CHM1_12220,228,468 - 20,255,665 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RTN4R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1607007
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.