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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | DIS3L | Human | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DIS3L mRNA | CTD | PMID:22079256 | DIS3L | Human | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dis3l (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of DIS3L mRNA | CTD | PMID:19465110 | DIS3L | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Dis3l (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DIS3L mRNA | CTD | PMID:33387578 | DIS3L | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dis3l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DIS3L mRNA | CTD | PMID:21570461 | DIS3L | Human | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Dis3l (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DIS3L mRNA | CTD | PMID:21215274 | DIS3L | Human | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dis3l (Rattus norvegicus) | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of DIS3L mRNA] | CTD | PMID:21215274 | DIS3L | Human | 2-methylcholine | affects expression | EXP | | 6480464 | beta-methylcholine affects the expression of DIS3L mRNA | CTD | PMID:21179406 | DIS3L | Human | 4,4'-sulfonyldiphenol | increases methylation | ISO | Dis3l (Mus musculus) | 6480464 | bisphenol S results in increased methylation of DIS3L exon | CTD | PMID:33297965 | DIS3L | Human | 4,4'-sulfonyldiphenol | affects methylation | ISO | Dis3l (Mus musculus) | 6480464 | bisphenol S affects the methylation of DIS3L gene | CTD | PMID:31683443 | DIS3L | Human | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of DIS3L mRNA | CTD | PMID:33167477 | DIS3L | Human | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of DIS3L mRNA | CTD | PMID:24449571 | DIS3L | Human | benzo[a]pyrene | increases expression | ISO | Dis3l (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of DIS3L mRNA | CTD | PMID:22228805 | DIS3L | Human | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of DIS3L promoter | CTD | PMID:27901495 | DIS3L | Human | bis(2-ethylhexyl) phthalate | increases expression | ISO | Dis3l (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of DIS3L mRNA | CTD | PMID:34319233 | DIS3L | Human | bisphenol A | multiple interactions | ISO | Dis3l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of DIS3L mRNA | CTD | PMID:26496021 | DIS3L | Human | bisphenol A | decreases expression | ISO | Dis3l (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of DIS3L mRNA | CTD | PMID:30816183 and PMID:32528016 | DIS3L | Human | bisphenol A | increases methylation | ISO | Dis3l (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of DIS3L gene | CTD | PMID:28505145 | DIS3L | Human | bisphenol A | increases expression | ISO | Dis3l (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of DIS3L mRNA | CTD | PMID:25181051 | DIS3L | Human | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of DIS3L mRNA | CTD | PMID:38568856 | DIS3L | Human | chlorpyrifos | decreases expression | ISO | Dis3l (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of DIS3L mRNA | CTD | PMID:37019170 | DIS3L | Human | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of DIS3L mRNA | CTD | PMID:19320972 | DIS3L | Human | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of DIS3L mRNA | CTD | PMID:19549813 | DIS3L | Human | CU-O LINKAGE | decreases expression | EXP | | 6480464 | cupric oxide results in decreased expression of DIS3L mRNA | CTD | PMID:22077320 | DIS3L | Human | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of DIS3L mRNA | CTD | PMID:25562108 | DIS3L | Human | DDE | decreases expression | EXP | | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of DIS3L mRNA and Dichlorodiphenyl Dichloroethylene results in decreased expression of DIS3L protein | CTD | PMID:32892578 | DIS3L | Human | DDE | increases expression | EXP | | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of DIS3L mRNA | CTD | PMID:38568856 | DIS3L | Human | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of DIS3L mRNA | CTD | PMID:29803840 | DIS3L | Human | epoxiconazole | decreases expression | ISO | Dis3l (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of DIS3L mRNA | CTD | PMID:35436446 | DIS3L | Human | fenthion | decreases expression | ISO | Dis3l (Mus musculus) | 6480464 | Fenthion results in decreased expression of DIS3L mRNA | CTD | PMID:34813904 | DIS3L | Human | formaldehyde | decreases expression | EXP | | 6480464 | Formaldehyde results in decreased expression of DIS3L mRNA | CTD | PMID:23649840 | DIS3L | Human | inulin | multiple interactions | ISO | Dis3l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of DIS3L mRNA | CTD | PMID:36331819 | DIS3L | Human | methamphetamine | increases expression | ISO | Dis3l (Mus musculus) | 6480464 | Methamphetamine results in increased expression of DIS3L mRNA | CTD | PMID:26307267 | DIS3L | Human | methotrexate | increases expression | EXP | | 6480464 | Methotrexate results in increased expression of DIS3L mRNA | CTD | PMID:17400583 | DIS3L | Human | paracetamol | affects expression | ISO | Dis3l (Mus musculus) | 6480464 | Acetaminophen affects the expression of DIS3L mRNA | CTD | PMID:17562736 | DIS3L | Human | paracetamol | decreases expression | ISO | Dis3l (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of DIS3L mRNA | CTD | PMID:33387578 | DIS3L | Human | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of DIS3L mRNA | CTD | PMID:21420995 | DIS3L | Human | perfluorohexanesulfonic acid | decreases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in decreased expression of DIS3L mRNA | CTD | PMID:25812627 | DIS3L | Human | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Dis3l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of DIS3L mRNA | CTD | PMID:36331819 | DIS3L | Human | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of DIS3L mRNA | CTD | PMID:25812627 | DIS3L | Human | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of DIS3L mRNA | CTD | PMID:25812627 | DIS3L | Human | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of DIS3L mRNA | CTD | PMID:22079256 | DIS3L | Human | potassium chromate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DIS3L mRNA | CTD | PMID:22079256 | DIS3L | Human | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of DIS3L mRNA | CTD | PMID:23557933 | DIS3L | Human | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of DIS3L mRNA | CTD | PMID:38568856 | DIS3L | Human | testosterone | multiple interactions | ISO | Dis3l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of DIS3L mRNA | CTD | PMID:26496021 | DIS3L | Human | thiram | decreases expression | EXP | | 6480464 | Thiram results in decreased expression of DIS3L mRNA | CTD | PMID:38568856 | DIS3L | Human | titanium dioxide | decreases methylation | ISO | Dis3l (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DIS3L promoter | CTD | PMID:35295148 | DIS3L | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of DIS3L mRNA | CTD | PMID:37042841 | DIS3L | Human | triptonide | decreases expression | ISO | Dis3l (Mus musculus) | 6480464 | triptonide results in decreased expression of DIS3L mRNA | CTD | PMID:33045310 | DIS3L | Human | tunicamycin | increases expression | EXP | | 6480464 | Tunicamycin results in increased expression of DIS3L mRNA | CTD | PMID:29453283 | DIS3L | Human | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of DIS3L mRNA | CTD | PMID:28818685 | DIS3L | Human | valproic acid | affects expression | ISO | Dis3l (Mus musculus) | 6480464 | Valproic Acid affects the expression of DIS3L mRNA | CTD | PMID:17292431 | DIS3L | Human | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of DIS3L mRNA | CTD | PMID:23179753 and PMID:29154799 | DIS3L | Human | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of DIS3L mRNA | CTD | PMID:25979313 | |