MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit) - Rat Genome Database

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Gene: MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit) Homo sapiens
Analyze
Symbol: MAT2B
Name: methionine adenosyltransferase 2 non-catalytic beta subunit
RGD ID: 1606800
HGNC Page HGNC:6905
Description: Enables enzyme binding activity and methionine adenosyltransferase regulator activity. Involved in S-adenosylmethionine biosynthetic process. Located in nucleus. Part of methionine adenosyltransferase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: beta regulatory subunit of methionine adenosyltransferase; dTDP-4-keto-6-deoxy-D-glucose 4-reductase; MAT II beta; MAT-II; MATIIbeta; methionine adenosyltransferase 2 subunit beta; methionine adenosyltransferase 2B; methionine adenosyltransferase II, beta; MGC12237; Nbla02999; putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase; putative protein product of Nbla02999; SDR23E1; short chain dehydrogenase/reductase family 23E, member 1; testicular tissue protein Li 118; TGR
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385163,503,064 - 163,519,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5163,503,114 - 163,519,558 (+)EnsemblGRCh38hg38GRCh38
GRCh375162,930,070 - 162,946,360 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,862,809 - 162,878,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera5158,964,332 - 158,980,423 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5158,029,749 - 158,046,037 (+)NCBIHuRef
CHM1_15162,362,532 - 162,378,812 (+)NCBICHM1_1
T2T-CHM13v2.05164,038,230 - 164,054,512 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. S-adenosylmethionine in liver health, injury, and cancer. Lu SC and Mato JM, Physiol Rev. 2012 Oct;92(4):1515-42. doi: 10.1152/physrev.00047.2011.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7213623   PMID:9055605   PMID:10644686   PMID:11076863   PMID:11230166   PMID:11256614   PMID:11337507   PMID:12477932   PMID:12671891   PMID:12878157   PMID:12975309   PMID:14702039  
PMID:14744259   PMID:15489336   PMID:16344560   PMID:16381901   PMID:18041713   PMID:18045590   PMID:18698677   PMID:18753136   PMID:19027726   PMID:19048631   PMID:19322201   PMID:19683694  
PMID:19913121   PMID:20421296   PMID:20628086   PMID:20634891   PMID:20877624   PMID:21516116   PMID:21630459   PMID:21813468   PMID:21829377   PMID:21832049   PMID:21873635   PMID:22773346  
PMID:22863883   PMID:22939629   PMID:23325601   PMID:23425511   PMID:23533145   PMID:23814050   PMID:23824909   PMID:23940030   PMID:24665060   PMID:25075345   PMID:25294683   PMID:25378659  
PMID:25416956   PMID:25544563   PMID:25794709   PMID:25963833   PMID:26186194   PMID:26344197   PMID:27548429   PMID:27573889   PMID:28298427   PMID:28380382   PMID:28514442   PMID:28515276  
PMID:29229926   PMID:29240606   PMID:29791485   PMID:30776190   PMID:30942439   PMID:30948266   PMID:31091453   PMID:31493275   PMID:31586073   PMID:31980649   PMID:32203420   PMID:32296183  
PMID:32353859   PMID:32710610   PMID:33060197   PMID:33957083   PMID:33961781   PMID:34189442   PMID:34349018   PMID:34780697   PMID:35032548   PMID:35256949   PMID:35696571   PMID:35831314  
PMID:35944360   PMID:35987950   PMID:36114006   PMID:36180891   PMID:36215168   PMID:36217030   PMID:36219356   PMID:37536630   PMID:37827155   PMID:38113892  


Genomics

Comparative Map Data
MAT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385163,503,064 - 163,519,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5163,503,114 - 163,519,558 (+)EnsemblGRCh38hg38GRCh38
GRCh375162,930,070 - 162,946,360 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,862,809 - 162,878,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera5158,964,332 - 158,980,423 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5158,029,749 - 158,046,037 (+)NCBIHuRef
CHM1_15162,362,532 - 162,378,812 (+)NCBICHM1_1
T2T-CHM13v2.05164,038,230 - 164,054,512 (+)NCBIT2T-CHM13v2.0
Mat2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,570,141 - 40,586,030 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1140,570,141 - 40,586,030 (-)EnsemblGRCm39 Ensembl
GRCm381140,679,314 - 40,695,203 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,679,314 - 40,695,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371140,492,816 - 40,506,115 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361140,522,737 - 40,536,036 (-)NCBIMGSCv36mm8
Celera1144,529,462 - 44,542,765 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.4NCBI
Mat2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,609,202 - 25,626,694 (-)NCBIGRCr8
mRatBN7.21025,106,928 - 25,122,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,106,930 - 25,122,777 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1029,861,993 - 29,877,026 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,350,532 - 29,365,565 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,837,185 - 24,852,218 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,832,096 - 25,848,045 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,832,072 - 25,847,994 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01025,686,294 - 25,701,795 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,713,132 - 25,718,879 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1024,666,794 - 24,680,351 (-)NCBICelera
Cytogenetic Map10q12NCBI
Mat2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540816,910,414 - 16,924,663 (+)NCBIChiLan1.0ChiLan1.0
MAT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24158,675,643 - 158,692,011 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15156,815,297 - 156,831,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05158,879,425 - 158,895,690 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15165,656,086 - 165,672,176 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5165,656,086 - 165,672,176 (+)Ensemblpanpan1.1panPan2
MAT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,703,991 - 47,726,363 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,709,576 - 47,726,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha447,597,100 - 47,621,728 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0448,134,581 - 48,159,235 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl448,137,166 - 48,156,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1447,918,036 - 47,942,655 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0448,076,525 - 48,101,129 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0448,596,150 - 48,620,797 (-)NCBIUU_Cfam_GSD_1.0
Mat2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213102,094,901 - 102,111,644 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936515544,037 - 561,182 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936515544,218 - 561,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1660,255,358 - 60,274,135 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11660,255,541 - 60,274,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21665,065,436 - 65,111,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103244929
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12365,776,808 - 65,792,871 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2365,779,437 - 65,792,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666097990,267 - 1,006,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mat2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473326,297,653 - 26,306,942 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473326,296,920 - 26,309,228 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MAT2B
11 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q32-35.3(chr5:149714592-181272151)x3 copy number gain See cases [RCV000051863] Chr5:149714592..181272151 [GRCh38]
Chr5:149094155..180699152 [GRCh37]
Chr5:149074348..180631758 [NCBI36]
Chr5:5q32-35.3		 pathogenic
GRCh38/hg38 5q33.3-35.3(chr5:160029980-181269805)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051865]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051865]|See cases [RCV000051865] Chr5:160029980..181269805 [GRCh38]
Chr5:159456987..180696806 [GRCh37]
Chr5:159389565..180629412 [NCBI36]
Chr5:5q33.3-35.3		 pathogenic
GRCh38/hg38 5q33.1-34(chr5:152761187-167248053)x1 copy number loss See cases [RCV000052144] Chr5:152761187..167248053 [GRCh38]
Chr5:152140747..166675058 [GRCh37]
Chr5:152120940..166607636 [NCBI36]
Chr5:5q33.1-34		 pathogenic
GRCh38/hg38 5q33.1-34(chr5:153195314-164014005)x1 copy number loss See cases [RCV000052145] Chr5:153195314..164014005 [GRCh38]
Chr5:152574874..163441011 [GRCh37]
Chr5:152555067..163373589 [NCBI36]
Chr5:5q33.1-34		 pathogenic
GRCh38/hg38 5q34(chr5:161909955-164086917)x1 copy number loss See cases [RCV000052147] Chr5:161909955..164086917 [GRCh38]
Chr5:161336961..163513923 [GRCh37]
Chr5:161269539..163446501 [NCBI36]
Chr5:5q34		 pathogenic
GRCh38/hg38 5q33.3-35.3(chr5:156825512-181269805)x3 copy number gain See cases [RCV000133847] Chr5:156825512..181269805 [GRCh38]
Chr5:156252523..180696806 [GRCh37]
Chr5:156185101..180629412 [NCBI36]
Chr5:5q33.3-35.3		 pathogenic
GRCh38/hg38 5q33.1-34(chr5:152443869-166104392)x1 copy number loss See cases [RCV000138282] Chr5:152443869..166104392 [GRCh38]
Chr5:151823430..165531397 [GRCh37]
Chr5:151803623..165463975 [NCBI36]
Chr5:5q33.1-34		 pathogenic
GRCh38/hg38 5q33.3-34(chr5:158941354-164386760)x1 copy number loss See cases [RCV000138895] Chr5:158941354..164386760 [GRCh38]
Chr5:158368362..163813766 [GRCh37]
Chr5:158300940..163746344 [NCBI36]
Chr5:5q33.3-34		 pathogenic
GRCh37/hg19 5q33.2-35.1(chr5:154886174-169757448)x1 copy number loss See cases [RCV000240059] Chr5:154886174..169757448 [GRCh37]
Chr5:5q33.2-35.1		 pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3		 likely benign
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3		 pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5q34(chr5:161650030-164111161)x3 copy number gain not provided [RCV000682609] Chr5:161650030..164111161 [GRCh37]
Chr5:5q34		 uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5q33.2-35.3(chr5:155344802-180693344)x3 copy number gain not provided [RCV000745284] Chr5:155344802..180693344 [GRCh37]
Chr5:5q33.2-35.3		 pathogenic
GRCh37/hg19 5q34(chr5:162851132-162950527)x3 copy number gain not provided [RCV000745303] Chr5:162851132..162950527 [GRCh37]
Chr5:5q34		 benign
GRCh37/hg19 5q34(chr5:162851132-162956242)x3 copy number gain not provided [RCV000745304] Chr5:162851132..162956242 [GRCh37]
Chr5:5q34		 benign
GRCh37/hg19 5q34(chr5:162851132-162956290)x3 copy number gain not provided [RCV000745305] Chr5:162851132..162956290 [GRCh37]
Chr5:5q34		 benign
GRCh37/hg19 5q33.3-35.1(chr5:156347980-169959880)x1 copy number loss not provided [RCV001005746] Chr5:156347980..169959880 [GRCh37]
Chr5:5q33.3-35.1		 pathogenic
GRCh37/hg19 5q34(chr5:162636748-163072415)x1 copy number loss not provided [RCV000847466] Chr5:162636748..163072415 [GRCh37]
Chr5:5q34		 uncertain significance
GRCh37/hg19 5q33.3-35.1(chr5:156597181-171166353)x3 copy number gain not provided [RCV000845588] Chr5:156597181..171166353 [GRCh37]
Chr5:5q33.3-35.1		 pathogenic
NM_013283.5(MAT2B):c.268A>G (p.Ile90Val) single nucleotide variant not specified [RCV004293850] Chr5:163513564 [GRCh38]
Chr5:162940570 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.905C>T (p.Thr302Ile) single nucleotide variant not provided [RCV000890098] Chr5:163518263 [GRCh38]
Chr5:162945269 [GRCh37]
Chr5:5q34		 benign
GRCh37/hg19 5q34(chr5:161880996-162958461)x3 copy number gain See cases [RCV001194529] Chr5:161880996..162958461 [GRCh37]
Chr5:5q34		 uncertain significance
GRCh37/hg19 5q32-35.3(chr5:149010383-180719789) copy number gain Hunter-McAlpine craniosynostosis [RCV002280612] Chr5:149010383..180719789 [GRCh37]
Chr5:5q32-35.3		 pathogenic
Single allele duplication not specified [RCV002286367] Chr5:158887731..164722046 [GRCh38]
Chr5:5q33.3-34		 uncertain significance
GRCh37/hg19 5q33.1-35.2(chr5:150535183-172906793)x3 copy number gain not provided [RCV002474507] Chr5:150535183..172906793 [GRCh37]
Chr5:5q33.1-35.2		 pathogenic
NM_013283.5(MAT2B):c.166G>T (p.Val56Phe) single nucleotide variant not specified [RCV004233779] Chr5:163512104 [GRCh38]
Chr5:162939110 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.758A>G (p.Asn253Ser) single nucleotide variant not specified [RCV004186166] Chr5:163517598 [GRCh38]
Chr5:162944604 [GRCh37]
Chr5:5q34		 uncertain significance
GRCh37/hg19 5q33.3-34(chr5:156786013-162945369)x1 copy number loss not provided [RCV002512289] Chr5:156786013..162945369 [GRCh37]
Chr5:5q33.3-34		 likely pathogenic
NM_013283.5(MAT2B):c.935G>A (p.Arg312Gln) single nucleotide variant not specified [RCV004199475] Chr5:163518293 [GRCh38]
Chr5:162945299 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.971T>C (p.Ile324Thr) single nucleotide variant not specified [RCV004203493] Chr5:163518329 [GRCh38]
Chr5:162945335 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.482A>G (p.Lys161Arg) single nucleotide variant not specified [RCV004095959] Chr5:163513950 [GRCh38]
Chr5:162940956 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.751T>G (p.Ser251Ala) single nucleotide variant not specified [RCV004179207] Chr5:163517591 [GRCh38]
Chr5:162944597 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.174T>G (p.Cys58Trp) single nucleotide variant not specified [RCV004154892] Chr5:163512112 [GRCh38]
Chr5:162939118 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.551T>C (p.Ile184Thr) single nucleotide variant not specified [RCV004255577] Chr5:163516542 [GRCh38]
Chr5:162943548 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.161A>T (p.His54Leu) single nucleotide variant not specified [RCV004264524] Chr5:163512099 [GRCh38]
Chr5:162939105 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.163G>A (p.Ala55Thr) single nucleotide variant not specified [RCV004416701] Chr5:163512101 [GRCh38]
Chr5:162939107 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.795T>G (p.Ile265Met) single nucleotide variant not specified [RCV004416704] Chr5:163517635 [GRCh38]
Chr5:162944641 [GRCh37]
Chr5:5q34		 uncertain significance
NM_013283.5(MAT2B):c.586G>C (p.Ala196Pro) single nucleotide variant not specified [RCV004416702] Chr5:163516577 [GRCh38]
Chr5:162943583 [GRCh37]
Chr5:5q34		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2343
Count of miRNA genes:851
Interacting mature miRNAs:999
Transcripts:ENST00000280969, ENST00000321757, ENST00000421814, ENST00000518095, ENST00000519719, ENST00000520449, ENST00000521838, ENST00000523606
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289409BW320_HBody weight QTL 320 (human)3.50.0002Body weightlean mass5160925164181538259Human

Markers in Region
STS-D25599  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375162,945,941 - 162,946,061UniSTSGRCh37
Build 365162,878,519 - 162,878,639RGDNCBI36
Celera5158,980,036 - 158,980,156RGD
Cytogenetic Map5q34-q35UniSTS
HuRef5158,045,619 - 158,045,739UniSTS
GeneMap99-GB4 RH Map5612.75UniSTS
NCBI RH Map5959.1UniSTS
RH93678  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375162,945,780 - 162,945,968UniSTSGRCh37
Build 365162,878,358 - 162,878,546RGDNCBI36
Celera5158,979,875 - 158,980,063RGD
Cytogenetic Map5q34-q35UniSTS
HuRef5158,045,458 - 158,045,646UniSTS
GeneMap99-GB4 RH Map5612.75UniSTS
D5S1942  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375162,939,022 - 162,939,138UniSTSGRCh37
Build 365162,871,600 - 162,871,716RGDNCBI36
Celera5158,973,117 - 158,973,233RGD
Cytogenetic Map5q34-q35UniSTS
HuRef5158,038,695 - 158,038,811UniSTS
SHGC-56899  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375162,943,647 - 162,943,756UniSTSGRCh37
Build 365162,876,225 - 162,876,334RGDNCBI36
Celera5158,977,742 - 158,977,851RGD
Cytogenetic Map5q34-q35UniSTS
HuRef5158,043,325 - 158,043,434UniSTS
G35510  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map1q42UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map10p12UniSTS
Cytogenetic Map9q13-q21UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map20q11.2-q13.2UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map2p25-p24UniSTS
Cytogenetic Map16pUniSTS
Cytogenetic Map4q21.3UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map12q24.31-q24.32UniSTS
Cytogenetic Map1p35UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic MapXp11UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map14q13.2UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map6pter-q22.33UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic Map9q21.33UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map11q14.2-q21UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic Map3q28UniSTS
Cytogenetic Map9p21.3UniSTS
Cytogenetic Map7p15.1UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map5q31-q32UniSTS
Cytogenetic Map18p11.2UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map12p13.33UniSTS
Cytogenetic Map18p11.22-p11.21UniSTS
Cytogenetic Map5q34-q35UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map12q23.3UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map17q24.3UniSTS
Cytogenetic Map7p14.2UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map1p36.2UniSTS
Cytogenetic Map12q14.1UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map11q13.3UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map10q26.1UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map12q13.1-q13.2UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic MapXp22.32UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map1q23.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map6pter-p12.1UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map17pUniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map20q13.33UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_182796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB073390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC112205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF113225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF182814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ243721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK096178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL136664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU279489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW966728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY033822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY223864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA146198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ395260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ413182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ413183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM005431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY091756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY366761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000280969   ⟹   ENSP00000280969
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,503,114 - 163,519,336 (+)Ensembl
Ensembl Acc Id: ENST00000321757   ⟹   ENSP00000325425
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,619 - 163,519,354 (+)Ensembl
Ensembl Acc Id: ENST00000421814   ⟹   ENSP00000397371
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,584 - 163,519,156 (+)Ensembl
Ensembl Acc Id: ENST00000518095   ⟹   ENSP00000428046
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,614 - 163,519,327 (+)Ensembl
Ensembl Acc Id: ENST00000519719
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,503,252 - 163,512,400 (+)Ensembl
Ensembl Acc Id: ENST00000520449   ⟹   ENSP00000431071
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,599 - 163,519,309 (+)Ensembl
Ensembl Acc Id: ENST00000521838
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,517,217 - 163,519,322 (+)Ensembl
Ensembl Acc Id: ENST00000523606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,626 - 163,519,149 (+)Ensembl
Ensembl Acc Id: ENST00000694938   ⟹   ENSP00000511605
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,503,233 - 163,519,008 (+)Ensembl
Ensembl Acc Id: ENST00000694939   ⟹   ENSP00000511606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,503,263 - 163,519,016 (+)Ensembl
Ensembl Acc Id: ENST00000694940   ⟹   ENSP00000511607
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,504,017 - 163,519,333 (+)Ensembl
Ensembl Acc Id: ENST00000694941   ⟹   ENSP00000511608
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,545 - 163,518,425 (+)Ensembl
Ensembl Acc Id: ENST00000694942
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,545 - 163,518,962 (+)Ensembl
Ensembl Acc Id: ENST00000694943   ⟹   ENSP00000511609
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,545 - 163,519,309 (+)Ensembl
Ensembl Acc Id: ENST00000694944
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,579 - 163,515,765 (+)Ensembl
Ensembl Acc Id: ENST00000694945
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,579 - 163,519,067 (+)Ensembl
Ensembl Acc Id: ENST00000694946   ⟹   ENSP00000511610
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,579 - 163,519,309 (+)Ensembl
Ensembl Acc Id: ENST00000694947   ⟹   ENSP00000511611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,579 - 163,519,309 (+)Ensembl
Ensembl Acc Id: ENST00000694952   ⟹   ENSP00000511614
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,599 - 163,519,016 (+)Ensembl
Ensembl Acc Id: ENST00000694953
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,614 - 163,518,804 (+)Ensembl
Ensembl Acc Id: ENST00000694954   ⟹   ENSP00000511615
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,619 - 163,519,333 (+)Ensembl
Ensembl Acc Id: ENST00000694955   ⟹   ENSP00000511616
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,621 - 163,519,333 (+)Ensembl
Ensembl Acc Id: ENST00000695023
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,596 - 163,512,544 (+)Ensembl
Ensembl Acc Id: ENST00000695024
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,626 - 163,519,309 (+)Ensembl
Ensembl Acc Id: ENST00000695025   ⟹   ENSP00000511652
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,794 - 163,519,333 (+)Ensembl
Ensembl Acc Id: ENST00000695026   ⟹   ENSP00000511653
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,803 - 163,519,333 (+)Ensembl
Ensembl Acc Id: ENST00000695027   ⟹   ENSP00000511654
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,818 - 163,519,333 (+)Ensembl
Ensembl Acc Id: ENST00000695028   ⟹   ENSP00000511655
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,907 - 163,519,558 (+)Ensembl
Ensembl Acc Id: ENST00000695029   ⟹   ENSP00000511656
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,505,949 - 163,519,333 (+)Ensembl
Ensembl Acc Id: ENST00000695030
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,506,067 - 163,512,106 (+)Ensembl
Ensembl Acc Id: ENST00000695031
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,513,265 - 163,516,711 (+)Ensembl
Ensembl Acc Id: ENST00000695032
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,515,802 - 163,519,309 (+)Ensembl
Ensembl Acc Id: ENST00000695033
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,515,813 - 163,518,369 (+)Ensembl
Ensembl Acc Id: ENST00000695034   ⟹   ENSP00000511961
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5163,515,823 - 163,519,309 (+)Ensembl
RefSeq Acc Id: NM_013283   ⟹   NP_037415
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385163,505,619 - 163,519,354 (+)NCBI
GRCh375162,930,070 - 162,946,359 (+)NCBI
Build 365162,865,163 - 162,878,906 (+)NCBI Archive
HuRef5158,029,749 - 158,046,037 (+)NCBI
CHM1_15162,364,995 - 162,378,812 (+)NCBI
T2T-CHM13v2.05164,040,784 - 164,054,512 (+)NCBI
Sequence:
RefSeq Acc Id: NM_182796   ⟹   NP_877725
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385163,503,064 - 163,519,353 (+)NCBI
GRCh375162,930,070 - 162,946,359 (+)NCBI
Build 365162,862,809 - 162,878,906 (+)NCBI Archive
HuRef5158,029,749 - 158,046,037 (+)NCBI
CHM1_15162,362,532 - 162,378,812 (+)NCBI
T2T-CHM13v2.05164,038,230 - 164,054,511 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_037415 (Get FASTA)   NCBI Sequence Viewer  
  NP_877725 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF28477 (Get FASTA)   NCBI Sequence Viewer  
  AAG39296 (Get FASTA)   NCBI Sequence Viewer  
  AAH05218 (Get FASTA)   NCBI Sequence Viewer  
  AAH66645 (Get FASTA)   NCBI Sequence Viewer  
  AAH93030 (Get FASTA)   NCBI Sequence Viewer  
  AAO73603 (Get FASTA)   NCBI Sequence Viewer  
  AAQ89058 (Get FASTA)   NCBI Sequence Viewer  
  ABD59011 (Get FASTA)   NCBI Sequence Viewer  
  ABD85290 (Get FASTA)   NCBI Sequence Viewer  
  AEE61029 (Get FASTA)   NCBI Sequence Viewer  
  BAE45720 (Get FASTA)   NCBI Sequence Viewer  
  BAF84608 (Get FASTA)   NCBI Sequence Viewer  
  BAG35283 (Get FASTA)   NCBI Sequence Viewer  
  BAH11664 (Get FASTA)   NCBI Sequence Viewer  
  CAB56837 (Get FASTA)   NCBI Sequence Viewer  
  CAB66599 (Get FASTA)   NCBI Sequence Viewer  
  EAW61517 (Get FASTA)   NCBI Sequence Viewer  
  EAW61518 (Get FASTA)   NCBI Sequence Viewer  
  EAW61519 (Get FASTA)   NCBI Sequence Viewer  
  EAW61520 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000280969
  ENSP00000280969.5
  ENSP00000325425
  ENSP00000325425.6
  ENSP00000397371.3
  ENSP00000428046.1
  ENSP00000431071.1
  ENSP00000511605.1
  ENSP00000511606.1
  ENSP00000511607.1
  ENSP00000511608.1
  ENSP00000511609.1
  ENSP00000511610.1
  ENSP00000511611.1
  ENSP00000511614.1
  ENSP00000511615.1
  ENSP00000511616.1
  ENSP00000511652.1
  ENSP00000511653.1
  ENSP00000511654.1
  ENSP00000511655.1
  ENSP00000511656.1
  ENSP00000511961.1
GenBank Protein Q9NZL9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_877725   ⟸   NM_182796
- Peptide Label: isoform 2
- UniProtKB: A8K7A4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_037415   ⟸   NM_013283
- Peptide Label: isoform 1
- UniProtKB: Q9H3E1 (UniProtKB/Swiss-Prot),   Q9BS89 (UniProtKB/Swiss-Prot),   Q6NYC7 (UniProtKB/Swiss-Prot),   Q567T7 (UniProtKB/Swiss-Prot),   Q3LIE8 (UniProtKB/Swiss-Prot),   Q27J92 (UniProtKB/Swiss-Prot),   Q1WAI7 (UniProtKB/Swiss-Prot),   B2R5Y6 (UniProtKB/Swiss-Prot),   Q9UJ54 (UniProtKB/Swiss-Prot),   Q9NZL9 (UniProtKB/Swiss-Prot),   A0A140VJP2 (UniProtKB/TrEMBL),   A0A8Q3WK80 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000428046   ⟸   ENST00000518095
Ensembl Acc Id: ENSP00000280969   ⟸   ENST00000280969
Ensembl Acc Id: ENSP00000325425   ⟸   ENST00000321757
Ensembl Acc Id: ENSP00000431071   ⟸   ENST00000520449
Ensembl Acc Id: ENSP00000397371   ⟸   ENST00000421814
Ensembl Acc Id: ENSP00000511605   ⟸   ENST00000694938
Ensembl Acc Id: ENSP00000511655   ⟸   ENST00000695028
Ensembl Acc Id: ENSP00000511609   ⟸   ENST00000694943
Ensembl Acc Id: ENSP00000511608   ⟸   ENST00000694941
Ensembl Acc Id: ENSP00000511653   ⟸   ENST00000695026
Ensembl Acc Id: ENSP00000511656   ⟸   ENST00000695029
Ensembl Acc Id: ENSP00000511654   ⟸   ENST00000695027
Ensembl Acc Id: ENSP00000511611   ⟸   ENST00000694947
Ensembl Acc Id: ENSP00000511614   ⟸   ENST00000694952
Ensembl Acc Id: ENSP00000511610   ⟸   ENST00000694946
Ensembl Acc Id: ENSP00000511607   ⟸   ENST00000694940
Ensembl Acc Id: ENSP00000511652   ⟸   ENST00000695025
Ensembl Acc Id: ENSP00000511606   ⟸   ENST00000694939
Ensembl Acc Id: ENSP00000511616   ⟸   ENST00000694955
Ensembl Acc Id: ENSP00000511961   ⟸   ENST00000695034
Ensembl Acc Id: ENSP00000511615   ⟸   ENST00000694954
Protein Domains
RmlD-like substrate binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NZL9-F1-model_v2 AlphaFold Q9NZL9 1-334 view protein structure

Promoters
RGD ID:6803353
Promoter ID:HG_KWN:51712
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000393908,   OTTHUMT00000252748
Position:
Human AssemblyChrPosition (strand)Source
Build 365162,862,746 - 162,863,246 (+)MPROMDB
RGD ID:6803352
Promoter ID:HG_KWN:51713
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000252749,   UC003LZL.1
Position:
Human AssemblyChrPosition (strand)Source
Build 365162,864,281 - 162,865,387 (+)MPROMDB
RGD ID:6853134
Promoter ID:EP74388
Type:initiation region
Name:HS_MAT2B
Description:Methionine adenosyltransferase II, beta.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 365162,865,194 - 162,865,254EPD
RGD ID:6871482
Promoter ID:EPDNEW_H8906
Type:initiation region
Name:MAT2B_2
Description:methionine adenosyltransferase 2B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8907  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385163,503,314 - 163,503,374EPDNEW
RGD ID:6871484
Promoter ID:EPDNEW_H8907
Type:initiation region
Name:MAT2B_1
Description:methionine adenosyltransferase 2B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8906  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385163,505,619 - 163,505,679EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6905 AgrOrtholog
COSMIC MAT2B COSMIC
Ensembl Genes ENSG00000038274 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000280969 ENTREZGENE
  ENST00000280969.9 UniProtKB/Swiss-Prot
  ENST00000321757 ENTREZGENE
  ENST00000321757.11 UniProtKB/Swiss-Prot
  ENST00000421814.7 UniProtKB/TrEMBL
  ENST00000518095.5 UniProtKB/Swiss-Prot
  ENST00000520449.2 UniProtKB/TrEMBL
  ENST00000694938.1 UniProtKB/TrEMBL
  ENST00000694939.1 UniProtKB/TrEMBL
  ENST00000694940.1 UniProtKB/TrEMBL
  ENST00000694941.1 UniProtKB/TrEMBL
  ENST00000694943.1 UniProtKB/Swiss-Prot
  ENST00000694946.1 UniProtKB/TrEMBL
  ENST00000694947.1 UniProtKB/TrEMBL
  ENST00000694952.1 UniProtKB/TrEMBL
  ENST00000694954.1 UniProtKB/TrEMBL
  ENST00000694955.1 UniProtKB/TrEMBL
  ENST00000695025.1 UniProtKB/TrEMBL
  ENST00000695026.1 UniProtKB/TrEMBL
  ENST00000695027.1 UniProtKB/TrEMBL
  ENST00000695028.1 UniProtKB/TrEMBL
  ENST00000695029.1 UniProtKB/TrEMBL
  ENST00000695034.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000038274 GTEx
HGNC ID HGNC:6905 ENTREZGENE
Human Proteome Map MAT2B Human Proteome Map
InterPro dTDP_dehydrorham_reduct UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RmlD-like-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:27430 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 27430 ENTREZGENE
OMIM 605527 OMIM
PANTHER METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10491 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RmlD_sub_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30648 PharmGKB
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140VJP2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8Q3SIE5_HUMAN UniProtKB/TrEMBL
  A0A8Q3WK74_HUMAN UniProtKB/TrEMBL
  A0A8Q3WK80 ENTREZGENE, UniProtKB/TrEMBL
  A0A8Q3WK84_HUMAN UniProtKB/TrEMBL
  A0A8Q3WK93_HUMAN UniProtKB/TrEMBL
  A0A8Q3WKR9_HUMAN UniProtKB/TrEMBL
  A0A8Q3WLC0_HUMAN UniProtKB/TrEMBL
  A0A8Q3WLP1_HUMAN UniProtKB/TrEMBL
  A8K7A4 ENTREZGENE, UniProtKB/TrEMBL
  B2R5Y6 ENTREZGENE
  E5RJR3_HUMAN UniProtKB/TrEMBL
  H7C0X7_HUMAN UniProtKB/TrEMBL
  MAT2B_HUMAN UniProtKB/Swiss-Prot
  Q1WAI7 ENTREZGENE
  Q27J92 ENTREZGENE
  Q3LIE8 ENTREZGENE
  Q567T7 ENTREZGENE
  Q6NYC7 ENTREZGENE
  Q9BS89 ENTREZGENE
  Q9H3E1 ENTREZGENE
  Q9NZL9 ENTREZGENE
  Q9UJ54 ENTREZGENE
UniProt Secondary B2R5Y6 UniProtKB/Swiss-Prot
  Q1WAI7 UniProtKB/Swiss-Prot
  Q27J92 UniProtKB/Swiss-Prot
  Q3LIE8 UniProtKB/Swiss-Prot
  Q567T7 UniProtKB/Swiss-Prot
  Q6NYC7 UniProtKB/Swiss-Prot
  Q9BS89 UniProtKB/Swiss-Prot
  Q9H3E1 UniProtKB/Swiss-Prot
  Q9UJ54 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-03 MAT2B  methionine adenosyltransferase 2 non-catalytic beta subunit  MAT2B  methionine adenosyltransferase 2B  Symbol and/or name change 19259463 PROVISIONAL
2016-02-02 MAT2B  methionine adenosyltransferase 2B  MAT2B  methionine adenosyltransferase II, beta  Symbol and/or name change 5135510 APPROVED