CIB4 (calcium and integrin binding family member 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: CIB4 (calcium and integrin binding family member 4) Homo sapiens
Analyze
Symbol: CIB4
Name: calcium and integrin binding family member 4
RGD ID: 1606728
HGNC Page HGNC:33703
Description: Enables calcium ion binding activity and magnesium ion binding activity.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: calcium and integrin-binding family member 4; KIP4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38226,581,205 - 26,641,366 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl226,581,205 - 26,641,366 (-)EnsemblGRCh38hg38GRCh38
GRCh37226,804,073 - 26,864,234 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,657,577 - 26,717,715 (-)NCBINCBI36Build 36hg18NCBI36
Celera226,647,704 - 26,707,827 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef226,543,509 - 26,603,418 (-)NCBIHuRef
CHM1_1226,734,122 - 26,794,199 (-)NCBICHM1_1
T2T-CHM13v2.0226,620,353 - 26,681,744 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15574431   PMID:20379614   PMID:21873635   PMID:22699663   PMID:22779914   PMID:26186194   PMID:28514442   PMID:32296183   PMID:33961781  


Genomics

Comparative Map Data
CIB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38226,581,205 - 26,641,366 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl226,581,205 - 26,641,366 (-)EnsemblGRCh38hg38GRCh38
GRCh37226,804,073 - 26,864,234 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,657,577 - 26,717,715 (-)NCBINCBI36Build 36hg18NCBI36
Celera226,647,704 - 26,707,827 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef226,543,509 - 26,603,418 (-)NCBIHuRef
CHM1_1226,734,122 - 26,794,199 (-)NCBICHM1_1
T2T-CHM13v2.0226,620,353 - 26,681,744 (-)NCBIT2T-CHM13v2.0
Cib4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39530,642,927 - 30,703,191 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl530,642,927 - 30,703,180 (-)EnsemblGRCm39 Ensembl
GRCm38530,485,583 - 30,545,845 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,485,583 - 30,545,836 (-)EnsemblGRCm38mm10GRCm38
MGSCv37530,787,957 - 30,848,209 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36530,762,164 - 30,822,417 (-)NCBIMGSCv36mm8
Celera527,963,768 - 28,024,353 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.59NCBI
Cib4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,560,105 - 31,623,403 (+)NCBIGRCr8
mRatBN7.2625,842,605 - 25,903,509 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,842,622 - 25,917,206 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0627,241,804 - 27,303,617 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,241,919 - 27,303,615 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0637,058,400 - 37,115,989 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,825,158 - 25,887,430 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera625,324,446 - 25,382,084 (+)NCBICelera
Cytogenetic Map6q14NCBI
Cib4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554698,604,799 - 8,669,916 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554698,604,866 - 8,669,890 (-)NCBIChiLan1.0ChiLan1.0
CIB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,876,073 - 99,936,088 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,880,053 - 99,940,041 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A26,578,051 - 26,670,672 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A26,669,870 - 26,729,792 (-)NCBIpanpan1.1PanPan1.1panPan2
CIB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11720,635,050 - 20,685,775 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1720,635,214 - 20,685,675 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1720,529,315 - 20,579,886 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01720,956,432 - 21,007,233 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1720,956,420 - 21,007,151 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11720,643,373 - 20,694,146 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01720,654,507 - 20,705,263 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01720,700,854 - 20,751,456 (-)NCBIUU_Cfam_GSD_1.0
Cib4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629264,945,208 - 64,996,761 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,842,964 - 5,894,306 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,805,911 - 5,894,306 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CIB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,406,908 - 112,457,138 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,415,709 - 112,457,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,405,976 - 119,456,544 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cib4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247388,718,687 - 8,771,025 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247388,704,726 - 8,813,441 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CIB4
12 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2p25.3-23.1(chr2:30141-31766749)x3 copy number gain See cases [RCV000052929] Chr2:30141..31766749 [GRCh38]
Chr2:30141..31991818 [GRCh37]
Chr2:20141..31845322 [NCBI36]
Chr2:2p25.3-23.1		 pathogenic
GRCh38/hg38 2p25.3-16.1(chr2:66097-55570637)x3 copy number gain See cases [RCV000052933] Chr2:66097..55570637 [GRCh38]
Chr2:66097..55797773 [GRCh37]
Chr2:56097..55651277 [NCBI36]
Chr2:2p25.3-16.1		 pathogenic
GRCh38/hg38 2p23.3(chr2:25759602-27297636)x3 copy number gain See cases [RCV000052629] Chr2:25759602..27297636 [GRCh38]
Chr2:25982471..27520504 [GRCh37]
Chr2:25835975..27374008 [NCBI36]
Chr2:2p23.3		 uncertain significance
NM_001105519.1(C2orf70):c.408C>T (p.Pro136=) single nucleotide variant Malignant melanoma [RCV000060537] Chr2:26577575 [GRCh38]
Chr2:26800443 [GRCh37]
Chr2:26653947 [NCBI36]
Chr2:2p23.3		 not provided
GRCh38/hg38 2p25.3-23.2(chr2:30341-28419664)x3 copy number gain See cases [RCV000135398] Chr2:30341..28419664 [GRCh38]
Chr2:30341..28642531 [GRCh37]
Chr2:20341..28496035 [NCBI36]
Chr2:2p25.3-23.2		 pathogenic
GRCh38/hg38 2p23.3(chr2:25064306-27154398)x1 copy number loss See cases [RCV000137065] Chr2:25064306..27154398 [GRCh38]
Chr2:25287175..27377266 [GRCh37]
Chr2:25140679..27230770 [NCBI36]
Chr2:2p23.3		 uncertain significance
GRCh38/hg38 2p25.3-22.3(chr2:12770-33711509)x3 copy number gain See cases [RCV000141829] Chr2:12770..33711509 [GRCh38]
Chr2:12770..33936576 [GRCh37]
Chr2:2770..33790080 [NCBI36]
Chr2:2p25.3-22.3		 pathogenic
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3 copy number gain See cases [RCV000141494] Chr2:7495123..87705899 [GRCh38]
Chr2:7635254..88005418 [GRCh37]
Chr2:7552705..87786533 [NCBI36]
Chr2:2p25.1-11.2		 benign
GRCh38/hg38 2p24.1-23.2(chr2:22579652-28525186)x1 copy number loss See cases [RCV000142071] Chr2:22579652..28525186 [GRCh38]
Chr2:22802524..28748053 [GRCh37]
Chr2:22656029..28601557 [NCBI36]
Chr2:2p24.1-23.2		 pathogenic
GRCh38/hg38 2p25.3-21(chr2:236816-45983232)x3 copy number gain See cases [RCV000143682] Chr2:236816..45983232 [GRCh38]
Chr2:236816..46210371 [GRCh37]
Chr2:226816..46063875 [NCBI36]
Chr2:2p25.3-21		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p23.3(chr2:26592685-27262646)x3 copy number gain See cases [RCV000448086] Chr2:26592685..27262646 [GRCh37]
Chr2:2p23.3		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p24.1-16.3(chr2:22665048-52850368)x3 copy number gain not provided [RCV000752875] Chr2:22665048..52850368 [GRCh37]
Chr2:2p24.1-16.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p23.3(chr2:26796310-26804143)x3 copy number gain not provided [RCV000740356] Chr2:26796310..26804143 [GRCh37]
Chr2:2p23.3		 benign
GRCh37/hg19 2p23.3-21(chr2:24881528-43460021)x3 copy number gain not provided [RCV001532444] Chr2:24881528..43460021 [GRCh37]
Chr2:2p23.3-21		 likely pathogenic
GRCh37/hg19 2p23.3-21(chr2:24601818-43466284)x3 copy number gain See cases [RCV001581099] Chr2:24601818..43466284 [GRCh37]
Chr2:2p23.3-21		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p23.3(chr2:26860458-27346266)x1 copy number loss Ritscher-Schinzel syndrome 4 [RCV001801216] Chr2:26860458..27346266 [GRCh37]
Chr2:2p23.3		 uncertain significance
GRCh37/hg19 2p23.3(chr2:26592685-27262646) copy number gain not specified [RCV002053078] Chr2:26592685..27262646 [GRCh37]
Chr2:2p23.3		 uncertain significance
NC_000002.11:g.(?_24443763)_(27746306_?)dup duplication Short-rib thoracic dysplasia 10 with or without polydactyly [RCV001911738] Chr2:24443763..27746306 [GRCh37]
Chr2:2p23.3		 uncertain significance
NC_000002.11:g.(?_24443763)_(29022169_?)dup duplication Tatton-Brown-Rahman overgrowth syndrome [RCV003113871]|not provided [RCV003113870] Chr2:24443763..29022169 [GRCh37]
Chr2:2p23.3-23.2		 uncertain significance|no classifications from unflagged records
NC_000002.11:g.(?_24443763)_(30143525_?)dup duplication not provided [RCV003113441] Chr2:24443763..30143525 [GRCh37]
Chr2:2p23.3-23.1		 uncertain significance
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13		 pathogenic
GRCh37/hg19 2p25.3-22.3(chr2:706460-35523639)x3 copy number gain not provided [RCV002473946] Chr2:706460..35523639 [GRCh37]
Chr2:2p25.3-22.3		 pathogenic
NM_001029881.3(CIB4):c.497A>G (p.His166Arg) single nucleotide variant Inborn genetic diseases [RCV002991156] Chr2:26582855 [GRCh38]
Chr2:26805723 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.185G>A (p.Arg62Gln) single nucleotide variant Inborn genetic diseases [RCV002902243] Chr2:26629411 [GRCh38]
Chr2:26852279 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.361G>A (p.Asp121Asn) single nucleotide variant Inborn genetic diseases [RCV002794226] Chr2:26583866 [GRCh38]
Chr2:26806734 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.319C>T (p.Arg107Cys) single nucleotide variant Inborn genetic diseases [RCV002752613] Chr2:26595185 [GRCh38]
Chr2:26818053 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.431C>A (p.Thr144Lys) single nucleotide variant Inborn genetic diseases [RCV002759559] Chr2:26583796 [GRCh38]
Chr2:26806664 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.66C>A (p.Phe22Leu) single nucleotide variant Inborn genetic diseases [RCV002645278] Chr2:26640556 [GRCh38]
Chr2:26863424 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.491T>C (p.Phe164Ser) single nucleotide variant Inborn genetic diseases [RCV002712826] Chr2:26582861 [GRCh38]
Chr2:26805729 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.536G>A (p.Arg179Gln) single nucleotide variant Inborn genetic diseases [RCV002964933] Chr2:26581385 [GRCh38]
Chr2:26804253 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.73A>G (p.Arg25Gly) single nucleotide variant Inborn genetic diseases [RCV002921532] Chr2:26640549 [GRCh38]
Chr2:26863417 [GRCh37]
Chr2:2p23.3		 uncertain significance
NM_001029881.3(CIB4):c.452C>T (p.Ser151Leu) single nucleotide variant Inborn genetic diseases [RCV003302650] Chr2:26582900 [GRCh38]
Chr2:26805768 [GRCh37]
Chr2:2p23.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:729
Count of miRNA genes:428
Interacting mature miRNAs:469
Transcripts:ENST00000288861, ENST00000403670, ENST00000405346
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D2S174  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37226,839,917 - 26,840,084UniSTSGRCh37
GRCh37226,839,873 - 26,840,075UniSTSGRCh37
Build 36226,693,421 - 26,693,588RGDNCBI36
Celera226,683,479 - 26,683,693UniSTS
Celera226,683,523 - 26,683,702RGD
Cytogenetic Map2p23.3UniSTS
HuRef226,579,219 - 26,579,400UniSTS
HuRef226,579,175 - 26,579,391UniSTS
Marshfield Genetic Map246.9UniSTS
Marshfield Genetic Map246.9RGD
Genethon Genetic Map250.1UniSTS
deCODE Assembly Map249.67UniSTS
Stanford-G3 RH Map21168.0UniSTS
Whitehead-RH Map2153.0UniSTS
Whitehead-YAC Contig Map2 UniSTS
GeneMap99-G3 RH Map21163.0UniSTS
G17673  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37226,833,193 - 26,833,420UniSTSGRCh37
Build 36226,686,697 - 26,686,924RGDNCBI36
Celera226,676,799 - 26,677,026RGD
Cytogenetic Map2p23.3UniSTS
HuRef226,572,498 - 26,572,725UniSTS
SHGC-151037  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37226,839,903 - 26,840,096UniSTSGRCh37
Build 36226,693,407 - 26,693,600RGDNCBI36
Celera226,683,509 - 26,683,714RGD
Cytogenetic Map2p23.3UniSTS
HuRef226,579,205 - 26,579,412UniSTS
TNG Radiation Hybrid Map219534.0UniSTS
RH65646  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37226,803,863 - 26,803,996UniSTSGRCh37
Build 36226,657,367 - 26,657,500RGDNCBI36
Celera226,647,494 - 26,647,627RGD
Cytogenetic Map2p23.3UniSTS
HuRef226,543,299 - 26,543,432UniSTS
GeneMap99-GB4 RH Map289.82UniSTS
D2S174  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2p23.3UniSTS
Stanford-G3 RH Map21168.0UniSTS
GeneMap99-G3 RH Map21163.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 13 6 315 12
Low 187 544 752 5 21 3 401 28 326 95 282 753 2 91 342 1
Below cutoff 1691 1178 508 140 333 58 1902 935 2084 166 559 646 86 841 1166 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001029881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017003329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017003330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017003331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054340510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054340511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054340512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC015977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW138422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX616371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC140923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000288861   ⟹   ENSP00000288861
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl226,581,205 - 26,641,366 (-)Ensembl
RefSeq Acc Id: ENST00000403670
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl226,581,207 - 26,605,563 (-)Ensembl
RefSeq Acc Id: ENST00000405346
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl226,581,340 - 26,623,627 (-)Ensembl
RefSeq Acc Id: NM_001029881   ⟹   NP_001025052
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38226,581,205 - 26,641,366 (-)NCBI
GRCh37226,804,073 - 26,864,211 (-)RGD
Build 36226,657,577 - 26,717,715 (-)NCBI Archive
Celera226,647,704 - 26,707,827 (-)RGD
HuRef226,543,509 - 26,603,418 (-)RGD
CHM1_1226,734,119 - 26,794,224 (-)NCBI
T2T-CHM13v2.0226,620,353 - 26,680,480 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011532514   ⟹   XP_011530816
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38226,581,205 - 26,641,366 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017003329   ⟹   XP_016858818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38226,581,205 - 26,638,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017003330   ⟹   XP_016858819
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38226,581,205 - 26,606,507 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054340510   ⟹   XP_054196485
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0226,620,353 - 26,681,744 (-)NCBI
RefSeq Acc Id: XM_054340511   ⟹   XP_054196486
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0226,620,353 - 26,677,752 (-)NCBI
RefSeq Acc Id: XM_054340512   ⟹   XP_054196487
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0226,620,353 - 26,645,625 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001025052   ⟸   NM_001029881
- UniProtKB: B2RU18 (UniProtKB/Swiss-Prot),   A0PJX0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011530816   ⟸   XM_011532514
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016858818   ⟸   XM_017003329
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016858819   ⟸   XM_017003330
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSP00000288861   ⟸   ENST00000288861
RefSeq Acc Id: XP_054196485   ⟸   XM_054340510
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054196486   ⟸   XM_054340511
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054196487   ⟸   XM_054340512
- Peptide Label: isoform X3
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0PJX0-F1-model_v2 AlphaFold A0PJX0 1-185 view protein structure

Promoters
RGD ID:6859846
Promoter ID:EPDNEW_H3088
Type:initiation region
Name:CIB4_1
Description:calcium and integrin binding family member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38226,641,349 - 26,641,409EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:33703 AgrOrtholog
COSMIC CIB4 COSMIC
Ensembl Genes ENSG00000157884 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000288861 ENTREZGENE
  ENST00000288861.5 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
GTEx ENSG00000157884 GTEx
HGNC ID HGNC:33703 ENTREZGENE
Human Proteome Map CIB4 Human Proteome Map
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
KEGG Report hsa:130106 UniProtKB/Swiss-Prot
NCBI Gene 130106 ENTREZGENE
OMIM 610646 OMIM
PANTHER CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 UniProtKB/Swiss-Prot
  CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 4 UniProtKB/Swiss-Prot
Pfam EF-hand_7 UniProtKB/Swiss-Prot
PharmGKB PA162382288 PharmGKB
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0PJX0 ENTREZGENE
  B2RU18 ENTREZGENE
  CIB4_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B2RU18 UniProtKB/Swiss-Prot