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Gene: BROX (BRO1 domain and CAAX motif containing) Homo sapiens
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Symbol: BROX
Name: BRO1 domain and CAAX motif containing
Description: Localizes to the extracellular exosome; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BRO1 domain containing protein; BRO1 domain- and CAAX motif-containing protein; BRO1 domain-containing protein BROX; Bro1-domain-containing protein; C1orf58; FLJ32421; MGC142195; MGC142197; RP11-452F19.1
Orthologs:
Mus musculus (house mouse) : Brox (BRO1 domain and CAAX motif containing)  MGI  Alliance
Rattus norvegicus (Norway rat) : Brox (BRO1 domain and CAAX motif containing)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brox (BRO1 domain and CAAX motif containing)
Pan paniscus (bonobo/pygmy chimpanzee) : BROX (BRO1 domain and CAAX motif containing)
Canis lupus familiaris (dog) : BROX (BRO1 domain and CAAX motif containing)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brox (BRO1 domain and CAAX motif containing)
Sus scrofa (pig) : BROX (BRO1 domain and CAAX motif containing)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381222,712,553 - 222,735,196 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371222,885,906 - 222,908,529 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361220,952,529 - 220,972,732 (+)NCBINCBI36hg18NCBI36
Celera1196,105,074 - 196,125,277 (+)NCBI
Cytogenetic Map1q41NCBI
HuRef1193,560,289 - 193,580,492 (+)NCBIHuRef
CHM1_11224,158,961 - 224,181,604 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BROX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606705
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.