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Gene: DEFB119 (defensin beta 119) Homo sapiens
Symbol: DEFB119
Name: defensin beta 119
Description: Exhibits lipopolysaccharide binding activity. Involved in antifungal innate immune response; defense response to Gram-negative bacterium; and defense response to Gram-positive bacterium. Predicted to localize to extracellular region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-defensin 119; beta-defensin 120; beta-defensin 19; beta-defensin 20; DEFB-19; DEFB-20; DEFB120; DEFB20; defensin, beta 119; defensin, beta 120; defensin, beta 19; defensin, beta 20; ESC42-RELA; ESC42-RELB; MGC71893
Mus musculus (house mouse) : Defb19 (defensin beta 19)  MGI  Alliance
Rattus norvegicus (Norway rat) : Defb24 (defensin beta 24)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Defb119 (defensin beta 119)
Pan paniscus (bonobo/pygmy chimpanzee) : DEFB119 (defensin beta 119)
Canis lupus familiaris (dog) : DEFB119 (defensin beta 119)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955647 (beta-defensin 121)
Sus scrofa (pig) : LOC100157086 (beta-defensin 119)
Chlorocebus sabaeus (African green monkey) : DEFB119 (defensin beta 119)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2031,377,164 - 31,390,590 (-)EnsemblGRCh38hg38GRCh38
GRCh382031,377,163 - 31,390,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372029,964,966 - 29,978,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,428,628 - 29,442,067 (-)NCBINCBI36hg18NCBI36
Celera2026,721,214 - 26,734,651 (-)NCBI
Cytogenetic Map20q11.21NCBI
HuRef2026,753,722 - 26,767,206 (-)NCBIHuRef
CHM1_12029,868,908 - 29,882,401 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DEFB119
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606419
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.