Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NPRL3 (NPR3 like, GATOR1 complex subunit) Homo sapiens
Analyze
Symbol: NPRL3
Name: NPR3 like, GATOR1 complex subunit
Description: Contributes to GTPase activator activity. Involved in cellular response to amino acid starvation and negative regulation of TOR signaling. Localizes to the GATOR1 complex and lysosomal membrane. Implicated in focal epilepsy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: -14 gene protein; alpha-globin regulatory element-containing gene protein; C16orf35; CGTHBA; conserved gene telomeric to alpha globin cluster; FFEVF3; GATOR complex protein NPRL3; HS-40; MARE; nitrogen permease regulator 3-like protein; NPR3; NPR3-like, GATOR1 complex subunit; RMD11
Orthologs:
Mus musculus (house mouse) : Nprl3 (nitrogen permease regulator-like 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nprl3 (NPR3-like, GATOR1 complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nprl3 (NPR3 like, GATOR1 complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Canis lupus familiaris (dog) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nprl3 (NPR3 like, GATOR1 complex subunit)
Sus scrofa (pig) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Chlorocebus sabaeus (African green monkey) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Heterocephalus glaber (naked mole-rat) : Nprl3 (NPR3 like, GATOR1 complex subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1684,271 - 138,860 (-)Ensembl
GRCh381685,386 - 138,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716135,800 - 188,697 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361675,800 - 128,672 (-)NCBINCBI36hg18NCBI36
Celera16337,330 - 390,318 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef1654,260 - 106,377 (-)NCBIHuRef
CHM1_116135,746 - 188,665 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NPRL3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606330
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.