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Gene: ARHGAP8 (Rho GTPase activating protein 8) Homo sapiens
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Symbol: ARHGAP8
Name: Rho GTPase activating protein 8
Description: Exhibits GTPase activator activity. Involved in positive regulation of ERK1 and ERK2 cascade. Predicted to localize to cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BCH domain-containing Cdc42GAP-like protein; BNIP-2 and Cdc42GAP homology domain-containing, proline-rich and Cdc42GAP-like protein subtype-1; BPGAP1; FLJ20185; PP610; rho GTPase-activating protein 8; rho-type GTPase-activating protein 8
Orthologs:
Mus musculus (house mouse) : Arhgap8 (Rho GTPase activating protein 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arhgap8 (Rho GTPase activating protein 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgap8 (Rho GTPase activating protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGAP8 (Rho GTPase activating protein 8)
Canis lupus familiaris (dog) : ARHGAP8 (Rho GTPase activating protein 8)
Sus scrofa (pig) : ARHGAP8 (Rho GTPase activating protein 8)
Chlorocebus sabaeus (African green monkey) : ARHGAP8 (Rho GTPase activating protein 8)
Heterocephalus glaber (naked mole-rat) : Arhgap8 (Rho GTPase activating protein 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2244,752,558 - 44,862,788 (+)EnsemblGRCh38hg38GRCh38
GRCh382244,752,558 - 44,862,784 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372245,148,438 - 45,258,664 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362243,527,102 - 43,637,328 (+)NCBINCBI36hg18NCBI36
Celera2229,060,362 - 29,170,596 (+)NCBI
Cytogenetic Map22q13.31NCBI
HuRef2228,096,688 - 28,205,949 (+)NCBIHuRef
CHM1_12245,141,077 - 45,217,387 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ARHGAP8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606315
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.