Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Rrp15 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RRP15 mRNA] | CTD | PMID:31150632 | (-)-alpha-phellandrene | decreases expression | EXP | | 6480464 | alpha phellandrene results in decreased expression of RRP15 mRNA | CTD | PMID:25075043 | 1,2-dimethylhydrazine | multiple interactions | ISO | Rrp15 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RRP15 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Rrp15 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of RRP15 mRNA | CTD | PMID:17555576 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of RRP15 mRNA | CTD | PMID:23019147 and PMID:31614463 | 17beta-estradiol | decreases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of RRP15 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rrp15 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RRP15 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of RRP15 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RRP15 mRNA | CTD | PMID:21632981 | 5-fluorouracil | decreases expression | EXP | | 6480464 | Fluorouracil results in decreased expression of RRP15 mRNA | CTD | PMID:16510598 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of RRP15 mRNA | CTD | PMID:23724009 and PMID:33167477 | alpha-phellandrene | decreases expression | EXP | | 6480464 | alpha phellandrene results in decreased expression of RRP15 mRNA | CTD | PMID:25075043 | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RRP15 mRNA] | CTD | PMID:32406909 | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of RRP15 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | Rrp15 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RRP15 mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | decreases expression | EXP | | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | decreases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of RRP15 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Rrp15 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of RRP15 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of RRP15 mRNA | CTD | PMID:32145629 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RRP15 mRNA and bisphenol A results in decreased expression of RRP15 protein | CTD | PMID:29275510 and PMID:37567409 | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of RRP15 mRNA | CTD | PMID:26079696 | cadmium dichloride | decreases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of RRP15 mRNA | CTD | PMID:33453195 | caffeine | decreases phosphorylation | EXP | | 6480464 | Caffeine results in decreased phosphorylation of RRP15 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Rrp15 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of RRP15 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RRP15 gene] | CTD | PMID:28238834 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of RRP15 mRNA | CTD | PMID:27594783 | cobalt dichloride | multiple interactions | EXP | | 6480464 | zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRP15 mRNA] | CTD | PMID:22202117 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of RRP15 mRNA | CTD | PMID:22202117 | coumarin | decreases phosphorylation | EXP | | 6480464 | coumarin results in decreased phosphorylation of RRP15 protein | CTD | PMID:35688186 | coumestrol | decreases expression | EXP | | 6480464 | Coumestrol results in decreased expression of RRP15 mRNA | CTD | PMID:19167446 | crotonaldehyde | decreases expression | EXP | | 6480464 | 2-butenal results in decreased expression of RRP15 mRNA | CTD | PMID:20471460 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of RRP15 mRNA | CTD | PMID:20106945 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of RRP15 mRNA | CTD | PMID:36621641 | dioxygen | multiple interactions | ISO | Rrp15 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of RRP15 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RRP15 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of RRP15 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | EXP | | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RRP15 protein | CTD | PMID:23301498 | ethanol | multiple interactions | EXP | | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of RRP15 mRNA | CTD | PMID:29432896 | ethyl methanesulfonate | decreases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in decreased expression of RRP15 mRNA | CTD | PMID:23649840 | flutamide | increases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of RRP15 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Rrp15 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RRP15 mRNA | CTD | PMID:22206623 | FR900359 | affects phosphorylation | EXP | | 6480464 | FR900359 affects the phosphorylation of RRP15 protein | CTD | PMID:37730182 | genistein | decreases expression | ISO | Rrp15 (Mus musculus) | 6480464 | Genistein results in decreased expression of RRP15 mRNA | CTD | PMID:32186404 | glafenine | increases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of RRP15 mRNA | CTD | PMID:24136188 | hydrogen peroxide | affects expression | EXP | | 6480464 | Hydrogen Peroxide affects the expression of RRP15 mRNA | CTD | PMID:20044591 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of RRP15 protein | CTD | PMID:32959892 | methoxychlor | affects methylation | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of RRP15 gene | CTD | PMID:35440735 | methyl methanesulfonate | decreases expression | EXP | | 6480464 | Methyl Methanesulfonate results in decreased expression of RRP15 mRNA | CTD | PMID:23649840 | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of RRP15 mRNA | CTD | PMID:25583101 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RRP15 mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of RRP15 mRNA | CTD | PMID:33387578 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of RRP15 mRNA | CTD | PMID:19159669 | SB 431542 | multiple interactions | EXP | | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide analog results in increased expression of RRP15 mRNA | CTD | PMID:25895662 | sodium dichromate | increases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | sodium bichromate results in increased expression of RRP15 mRNA | CTD | PMID:25993096 | tetrachloromethane | increases expression | ISO | Rrp15 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of RRP15 mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | increases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of RRP15 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | ISO | Rrp15 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RRP15 mRNA] | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Rrp15 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of RRP15 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichostatin A | decreases expression | EXP | | 6480464 | trichostatin A results in decreased expression of RRP15 mRNA | CTD | PMID:24935251 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of RRP15 mRNA | CTD | PMID:24935251 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of RRP15 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of RRP15 mRNA | CTD | PMID:24935251 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RRP15 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of RRP15 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of RRP15 mRNA | CTD | PMID:25979313 | zinc dichloride | multiple interactions | EXP | | 6480464 | zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRP15 mRNA] | CTD | PMID:22202117 | |