Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SHLD1 (shieldin complex subunit 1) Homo sapiens
Analyze
Symbol: SHLD1
Name: shieldin complex subunit 1
Description: Involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Localizes to site of double-strand break; INTERACTS WITH benzo[a]pyrene; calcitriol; dicrotophos.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C20orf196; chromosome 20 open reading frame 196; FLJ25067; hypothetical protein LOC149840; RINN1-REV7-interacting novel NHEJ regulator 3; RINN3; RP4-784N16.1; shield complex subunit 1; uncharacterized protein C20orf196
Orthologs:
Mus musculus (house mouse) : Shld1 (shieldin complex subunit 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Shld1 (shieldin complex subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shld1 (shieldin complex subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SHLD1 (shieldin complex subunit 1)
Canis lupus familiaris (dog) : SHLD1 (shieldin complex subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shld1 (shieldin complex subunit 1)
Sus scrofa (pig) : SHLD1 (shieldin complex subunit 1)
Chlorocebus sabaeus (African green monkey) : SHLD1 (shieldin complex subunit 1)
Heterocephalus glaber (naked mole-rat) : Shld1 (shieldin complex subunit 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl205,750,393 - 5,864,395 (+)EnsemblGRCh38hg38GRCh38
GRCh38205,750,286 - 5,864,407 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37205,731,043 - 5,844,558 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36205,679,043 - 5,792,558 (+)NCBINCBI36hg18NCBI36
Celera205,802,650 - 5,916,186 (+)NCBI
Cytogenetic Map20p12.3NCBI
HuRef205,688,686 - 5,801,246 (+)NCBIHuRef
CHM1_1205,731,629 - 5,845,586 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SHLD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606148
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.