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Gene: TUSC1 (tumor suppressor candidate 1) Homo sapiens
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Symbol: TUSC1
Name: tumor suppressor candidate 1
Description: This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCDC89B; MGC131751; TSG-9; TSG9; tumor suppressor candidate gene 1 protein
Orthologs:
Mus musculus (house mouse) : Tusc1 (tumor suppressor candidate 1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TUSC1 (tumor suppressor candidate 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tusc1 (tumor suppressor candidate 1)
Sus scrofa (pig) : TUSC1 (tumor suppressor candidate 1)
Chlorocebus sabaeus (green monkey) : TUSC1 (tumor suppressor candidate 1)
Heterocephalus glaber (naked mole-rat) : Tusc1 (tumor suppressor candidate 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl925,676,389 - 25,678,440 (-)Ensembl
GRCh38925,676,389 - 25,678,858 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37925,676,387 - 25,678,856 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36925,666,387 - 25,668,856 (-)NCBINCBI36hg18NCBI36
Celera925,603,429 - 25,605,898 (-)NCBI
Cytogenetic Map9p21.2NCBI
HuRef925,628,732 - 25,631,200 (-)NCBIHuRef
CHM1_1925,676,275 - 25,678,743 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
 
More on TUSC1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606109
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.