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Gene: INSC (INSC spindle orientation adaptor protein) Homo sapiens
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Symbol: INSC
Name: INSC spindle orientation adaptor protein
Description: Exhibits protein domain specific binding activity and protein-macromolecule adaptor activity. Involved in regulation of protein stability. Localizes to plasma membrane and protein-containing complex. Colocalizes with cell cortex.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inscuteable homolog; inscuteable homolog (Drosophila); inscuteable spindle orientation adaptor protein; protein inscuteable homolog
Orthologs:
Mus musculus (house mouse) : Insc (INSC spindle orientation adaptor protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Insc (INSC, spindle orientation adaptor protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Insc (INSC spindle orientation adaptor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : INSC (INSC spindle orientation adaptor protein)
Canis lupus familiaris (dog) : INSC (INSC spindle orientation adaptor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Insc (INSC spindle orientation adaptor protein)
Sus scrofa (pig) : INSC (INSC spindle orientation adaptor protein)
Chlorocebus sabaeus (African green monkey) : INSC (INSC spindle orientation adaptor protein)
Heterocephalus glaber (naked mole-rat) : Insc (INSC spindle orientation adaptor protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1115,112,424 - 15,247,208 (+)EnsemblGRCh38hg38GRCh38
GRCh381115,111,416 - 15,269,675 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371115,133,970 - 15,268,754 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361115,090,546 - 15,225,330 (+)NCBINCBI36hg18NCBI36
Celera1115,261,213 - 15,395,928 (+)NCBI
Cytogenetic Map11p15.2NCBI
HuRef1114,817,520 - 14,952,207 (+)NCBIHuRef
CHM1_11115,132,981 - 15,268,351 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on INSC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606091
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.