NCAPG (non-SMC condensin I complex subunit G) - Rat Genome Database

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Gene: NCAPG (non-SMC condensin I complex subunit G) Homo sapiens
Analyze
Symbol: NCAPG
Name: non-SMC condensin I complex subunit G
RGD ID: 1605960
HGNC Page HGNC
Description: Involved in mitotic chromosome condensation. Localizes to condensin complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAPG; CHCG; chromosome condensation protein G; chromosome-associated protein G; condensin complex subunit 3; condensin subunit CAP-G; FLJ12450; HCAP-G; melanoma antigen NY-MEL-3; MGC126525; non-SMC condensin I complex, subunit G; NY-MEL-3; XCAP-G homolog; YCG1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: NCAPGP1   NCAPGP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl417,810,979 - 17,844,865 (+)EnsemblGRCh38hg38GRCh38
GRCh38417,810,942 - 17,844,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37417,812,602 - 17,846,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36417,421,623 - 17,455,586 (+)NCBINCBI36hg18NCBI36
Celera418,277,506 - 18,311,469 (+)NCBI
Cytogenetic Map4p15.31NCBI
HuRef417,167,187 - 17,201,238 (+)NCBIHuRef
CHM1_1417,810,377 - 17,844,429 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (EXP)
2-butoxyethanol  (ISO)
2-methylcholine  (EXP)
5-fluorouracil  (EXP)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (EXP)
azathioprine  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
butanal  (EXP)
cadmium atom  (EXP)
calcitriol  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
coumestrol  (EXP)
cyclosporin A  (EXP,ISO)
dexamethasone  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (EXP)
dioxygen  (EXP)
disodium selenite  (EXP)
doxorubicin  (EXP)
Enterolactone  (EXP)
enzyme inhibitor  (EXP)
furan  (ISO)
genistein  (EXP)
lead(0)  (EXP)
lead(2+)  (EXP)
leflunomide  (EXP)
lipopolysaccharide  (EXP,ISO)
lucanthone  (EXP)
menadione  (EXP)
methamphetamine  (ISO)
methyl methanesulfonate  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-Nitrosopyrrolidine  (EXP)
nickel atom  (EXP)
ozone  (ISO)
paclitaxel  (EXP)
palbociclib  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (EXP)
phenethyl isothiocyanate  (EXP)
phenformin  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (ISO)
piroxicam  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
quercetin  (EXP,ISO)
resveratrol  (EXP)
rotenone  (EXP,ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (EXP)
sunitinib  (EXP)
testosterone  (EXP)
tetrachloroethene  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
Tributyltin oxide  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (EXP)
tunicamycin  (EXP)
valproic acid  (EXP)
vincaleukoblastine  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10910072   PMID:11136719   PMID:12138188   PMID:12477932   PMID:14532007   PMID:14702039   PMID:14968112   PMID:15148359   PMID:15489334   PMID:15662014   PMID:16341674   PMID:16543152  
PMID:16565220   PMID:17081983   PMID:17268547   PMID:17353931   PMID:17611626   PMID:18029348   PMID:18391951   PMID:18977199   PMID:19454010   PMID:19946888   PMID:20189936   PMID:20467437  
PMID:20546612   PMID:21145461   PMID:21873635   PMID:22145905   PMID:22863883   PMID:22939629   PMID:22990118   PMID:23027611   PMID:24797263   PMID:24981860   PMID:25281560   PMID:25429064  
PMID:25609649   PMID:25921289   PMID:26166704   PMID:26186194   PMID:26344197   PMID:26496610   PMID:26618866   PMID:26933822   PMID:26972000   PMID:27248496   PMID:27634302   PMID:27880917  
PMID:28514442   PMID:28515276   PMID:28685749   PMID:28712289   PMID:28737823   PMID:29053956   PMID:29229926   PMID:29331416   PMID:29467282   PMID:29507755   PMID:29509190   PMID:29608247  
PMID:29845934   PMID:29955894   PMID:30021884   PMID:30089216   PMID:30463901   PMID:30833792   PMID:30948266   PMID:31022357   PMID:31067453   PMID:31073040   PMID:31081967   PMID:31091453  
PMID:31586073   PMID:31995728   PMID:32416067   PMID:32683421   PMID:32786267   PMID:32980450  


Genomics

Comparative Map Data
NCAPG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl417,810,979 - 17,844,865 (+)EnsemblGRCh38hg38GRCh38
GRCh38417,810,942 - 17,844,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37417,812,602 - 17,846,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36417,421,623 - 17,455,586 (+)NCBINCBI36hg18NCBI36
Celera418,277,506 - 18,311,469 (+)NCBI
Cytogenetic Map4p15.31NCBI
HuRef417,167,187 - 17,201,238 (+)NCBIHuRef
CHM1_1417,810,377 - 17,844,429 (+)NCBICHM1_1
Ncapg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39545,827,212 - 45,858,491 (+)NCBIGRCm39mm39
GRCm39 Ensembl545,827,261 - 45,857,888 (+)Ensembl
GRCm38545,669,891 - 45,700,547 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl545,669,919 - 45,700,546 (+)EnsemblGRCm38mm10GRCm38
MGSCv37546,061,164 - 46,091,786 (+)NCBIGRCm37mm9NCBIm37
Celera543,092,590 - 43,123,298 (+)NCBICelera
Cytogenetic Map5B3NCBI
Ncapg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21465,404,235 - 65,432,902 (-)NCBI
Rnor_6.0 Ensembl1469,899,128 - 69,927,938 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01469,898,268 - 69,927,885 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01469,941,502 - 69,970,627 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41470,465,952 - 70,494,296 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1464,386,930 - 64,415,898 (-)NCBICelera
Cytogenetic Map14q11NCBI
Ncapg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554806,399,960 - 6,430,645 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554806,399,891 - 6,430,617 (-)NCBIChiLan1.0ChiLan1.0
NCAPG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1417,527,055 - 17,561,038 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl417,524,826 - 17,571,798 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0412,232,614 - 12,265,320 (+)NCBIMhudiblu_PPA_v0panPan3
NCAPG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1391,279,800 - 91,322,679 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl391,281,077 - 91,322,803 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha393,745,415 - 93,788,076 (-)NCBI
ROS_Cfam_1.0392,276,176 - 92,319,082 (-)NCBI
UMICH_Zoey_3.1391,449,153 - 91,492,044 (-)NCBI
UNSW_CanFamBas_1.0391,502,487 - 91,545,387 (-)NCBI
UU_Cfam_GSD_1.0391,886,702 - 91,929,596 (-)NCBI
Ncapg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528556,706,655 - 56,743,580 (-)NCBI
SpeTri2.0NW_00493647710,408,347 - 10,445,361 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCAPG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl812,759,639 - 12,810,050 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1812,759,225 - 12,807,164 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2812,560,111 - 12,603,284 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NCAPG
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12732,380,722 - 32,413,659 (-)NCBI
ChlSab1.1 Ensembl2732,377,575 - 32,413,494 (-)Ensembl
Ncapg
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475514,067,931 - 14,100,593 (-)NCBI

Position Markers
A009L13  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37417,843,333 - 17,843,473UniSTSGRCh37
Build 36417,452,431 - 17,452,571RGDNCBI36
Celera418,308,314 - 18,308,454RGD
Cytogenetic Map4p15.31UniSTS
Cytogenetic Map4p15.33UniSTS
HuRef417,198,083 - 17,198,223UniSTS
GeneMap99-GB4 RH Map480.17UniSTS
RH103028  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37417,844,931 - 17,845,068UniSTSGRCh37
Build 36417,454,029 - 17,454,166RGDNCBI36
Celera418,309,912 - 18,310,049RGD
Cytogenetic Map4p15.31UniSTS
Cytogenetic Map4p15.33UniSTS
HuRef417,199,681 - 17,199,818UniSTS
GeneMap99-GB4 RH Map480.17UniSTS
STS-R67597  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37417,843,318 - 17,843,449UniSTSGRCh37
Build 36417,452,416 - 17,452,547RGDNCBI36
Celera418,308,299 - 18,308,430RGD
Cytogenetic Map4p15.31UniSTS
Cytogenetic Map4p15.33UniSTS
HuRef417,198,068 - 17,198,199UniSTS
GeneMap99-GB4 RH Map479.97UniSTS
SHGC-67761  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37417,842,935 - 17,843,115UniSTSGRCh37
Build 36417,452,033 - 17,452,213RGDNCBI36
Celera418,307,916 - 18,308,096RGD
Cytogenetic Map4p15.31UniSTS
Cytogenetic Map4p15.33UniSTS
HuRef417,197,685 - 17,197,865UniSTS
GeneMap99-GB4 RH Map480.17UniSTS
NCBI RH Map4217.1UniSTS
G32642  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37417,843,333 - 17,843,473UniSTSGRCh37
Celera418,308,314 - 18,308,454UniSTS
Cytogenetic Map4p15.31UniSTS
Cytogenetic Map4p15.33UniSTS
HuRef417,198,083 - 17,198,223UniSTS
RH102048  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37417,811,265 - 17,812,159UniSTSGRCh37
Celera418,276,246 - 18,277,140UniSTS
Cytogenetic Map4p15.33UniSTS
Cytogenetic Map4p15.31UniSTS
HuRef417,166,016 - 17,166,910UniSTS
GeneMap99-GB4 RH Map478.23UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1866
Count of miRNA genes:868
Interacting mature miRNAs:1030
Transcripts:ENST00000251496, ENST00000509719, ENST00000510063, ENST00000513226, ENST00000514176
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 206 22 69 59 711 62 282 58 121 74 619 286 10 3 3
Low 909 882 573 243 903 154 2198 234 762 171 345 800 92 1 616 1256 3 1
Below cutoff 1312 2057 1069 315 333 242 1859 1883 2765 172 491 524 73 587 1513 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_073124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017008543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017008544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB013299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF235023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF331796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK022512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG398543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM743260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX474610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB451361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000251496   ⟹   ENSP00000251496
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl417,810,979 - 17,844,865 (+)Ensembl
RefSeq Acc Id: ENST00000509719
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl417,817,232 - 17,823,147 (+)Ensembl
RefSeq Acc Id: ENST00000510063   ⟹   ENSP00000425625
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl417,823,699 - 17,837,161 (+)Ensembl
RefSeq Acc Id: ENST00000513226
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl417,811,028 - 17,813,346 (+)Ensembl
RefSeq Acc Id: ENST00000514176   ⟹   ENSP00000423042
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl417,811,022 - 17,843,448 (+)Ensembl
RefSeq Acc Id: NM_022346   ⟹   NP_071741
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38417,810,979 - 17,844,865 (+)NCBI
GRCh37417,812,436 - 17,846,488 (+)NCBI
Build 36417,421,623 - 17,455,586 (+)NCBI Archive
Celera418,277,506 - 18,311,469 (+)RGD
HuRef417,167,187 - 17,201,238 (+)NCBI
CHM1_1417,810,377 - 17,844,429 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073124
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38417,810,979 - 17,844,865 (+)NCBI
GRCh37417,812,436 - 17,846,488 (+)NCBI
HuRef417,167,187 - 17,201,238 (+)NCBI
CHM1_1417,810,377 - 17,844,429 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011513876   ⟹   XP_011512178
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38417,810,962 - 17,844,099 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017008543   ⟹   XP_016864032
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38417,810,942 - 17,844,099 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017008544   ⟹   XP_016864033
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38417,810,982 - 17,844,099 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_071741   ⟸   NM_022346
- UniProtKB: Q9BPX3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011512178   ⟸   XM_011513876
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_016864032   ⟸   XM_017008543
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016864033   ⟸   XM_017008544
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000425625   ⟸   ENST00000510063
RefSeq Acc Id: ENSP00000423042   ⟸   ENST00000514176
RefSeq Acc Id: ENSP00000251496   ⟸   ENST00000251496
Protein Domains
Cnd3

Promoters
RGD ID:6802155
Promoter ID:HG_KWN:47943
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_017741,   NM_022346
Position:
Human AssemblyChrPosition (strand)Source
Build 36417,420,526 - 17,422,362 (-)MPROMDB
RGD ID:6815491
Promoter ID:HG_MRA:11805
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Jurkat
Transcripts:AK023147
Position:
Human AssemblyChrPosition (strand)Source
Build 36417,422,406 - 17,422,906 (+)MPROMDB
RGD ID:6867102
Promoter ID:EPDNEW_H6716
Type:initiation region
Name:NCAPG_1
Description:non-SMC condensin I complex subunit G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38417,810,992 - 17,811,052EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4p16.3-15.1(chr4:72555-28066309)x1 copy number loss See cases [RCV000051642] Chr4:72555..28066309 [GRCh38]
Chr4:72447..28067931 [GRCh37]
Chr4:62447..27677029 [NCBI36]
Chr4:4p16.3-15.1
pathogenic
GRCh38/hg38 4p15.33-15.31(chr4:14061129-20121834)x1 copy number loss See cases [RCV000051220] Chr4:14061129..20121834 [GRCh38]
Chr4:14062753..20123457 [GRCh37]
Chr4:13671851..19732555 [NCBI36]
Chr4:4p15.33-15.31
pathogenic
GRCh38/hg38 4p16.3-15.2(chr4:51519-26519788)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051752]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051752]|See cases [RCV000051752] Chr4:51519..26519788 [GRCh38]
Chr4:51413..26521410 [GRCh37]
Chr4:41413..26130508 [NCBI36]
Chr4:4p16.3-15.2
pathogenic
GRCh38/hg38 4p16.3-15.1(chr4:72555-33130620)x3 copy number gain See cases [RCV000051753] Chr4:72555..33130620 [GRCh38]
Chr4:72447..33132242 [GRCh37]
Chr4:62447..32808637 [NCBI36]
Chr4:4p16.3-15.1
pathogenic
GRCh38/hg38 4p15.33-15.31(chr4:14659764-18274924)x3 copy number gain See cases [RCV000051769] Chr4:14659764..18274924 [GRCh38]
Chr4:14661388..18276547 [GRCh37]
Chr4:14270486..17885645 [NCBI36]
Chr4:4p15.33-15.31
pathogenic
GRCh38/hg38 4p16.3-14(chr4:85149-38700366)x3 copy number gain See cases [RCV000051757] Chr4:85149..38700366 [GRCh38]
Chr4:85040..38701987 [GRCh37]
Chr4:75040..38378382 [NCBI36]
Chr4:4p16.3-14
pathogenic
GRCh38/hg38 4p16.3-15.2(chr4:85149-22450018)x3 copy number gain See cases [RCV000051755] Chr4:85149..22450018 [GRCh38]
Chr4:85040..22451641 [GRCh37]
Chr4:75040..22060739 [NCBI36]
Chr4:4p16.3-15.2
pathogenic
GRCh38/hg38 4p16.3-14(chr4:72555-39477144)x3 copy number gain See cases [RCV000133677] Chr4:72555..39477144 [GRCh38]
Chr4:72447..39478764 [GRCh37]
Chr4:62447..39155159 [NCBI36]
Chr4:4p16.3-14
pathogenic
GRCh38/hg38 4p15.32-15.1(chr4:16925022-32113076)x1 copy number loss See cases [RCV000135806] Chr4:16925022..32113076 [GRCh38]
Chr4:16926645..32114698 [GRCh37]
Chr4:16535743..31758596 [NCBI36]
Chr4:4p15.32-15.1
pathogenic|likely pathogenic
GRCh38/hg38 4p16.3-12(chr4:36424-47491595)x3 copy number gain See cases [RCV000137261] Chr4:36424..47491595 [GRCh38]
Chr4:36424..47493612 [GRCh37]
Chr4:26424..47188369 [NCBI36]
Chr4:4p16.3-12
pathogenic
GRCh38/hg38 4p16.3-15.31(chr4:72555-21022414)x3 copy number gain See cases [RCV000138305] Chr4:72555..21022414 [GRCh38]
Chr4:72447..21024037 [GRCh37]
Chr4:62447..20633135 [NCBI36]
Chr4:4p16.3-15.31
pathogenic
GRCh38/hg38 4p15.32-15.2(chr4:17041381-22524915)x1 copy number loss See cases [RCV000139200] Chr4:17041381..22524915 [GRCh38]
Chr4:17043004..22526538 [GRCh37]
Chr4:16652102..22135636 [NCBI36]
Chr4:4p15.32-15.2
uncertain significance
GRCh38/hg38 4p16.3-15.31(chr4:68453-20385608)x1 copy number loss See cases [RCV000143713] Chr4:68453..20385608 [GRCh38]
Chr4:68345..20387231 [GRCh37]
Chr4:58345..19996329 [NCBI36]
Chr4:4p16.3-15.31
pathogenic
GRCh37/hg19 4p16.3-15.31(chr4:44020-19796182)x1 copy number loss See cases [RCV000203431] Chr4:44020..19796182 [GRCh37]
Chr4:4p16.3-15.31
pathogenic
GRCh37/hg19 4p16.3-15.1(chr4:71552-29006745)x1 copy number loss See cases [RCV000240003] Chr4:71552..29006745 [GRCh37]
Chr4:4p16.3-15.1
pathogenic
GRCh37/hg19 4p16.1-15.31(chr4:6447048-20490737)x3 copy number gain See cases [RCV000240007] Chr4:6447048..20490737 [GRCh37]
Chr4:4p16.1-15.31
pathogenic
GRCh37/hg19 4p16.3-11(chr4:12440-49064044)x3 copy number gain See cases [RCV000240562] Chr4:12440..49064044 [GRCh37]
Chr4:4p16.3-11
pathogenic
GRCh37/hg19 4p16.3-11(chr4:68345-49089361)x3 copy number gain See cases [RCV000449078] Chr4:68345..49089361 [GRCh37]
Chr4:4p16.3-11
pathogenic
GRCh37/hg19 4p15.32-15.31(chr4:16834640-17818885)x3 copy number gain See cases [RCV000599152] Chr4:16834640..17818885 [GRCh37]
Chr4:4p15.32-15.31
uncertain significance
GRCh37/hg19 4p16.3-15.31(chr4:68345-20533787)x1 copy number loss See cases [RCV000449197] Chr4:68345..20533787 [GRCh37]
Chr4:4p16.3-15.31
pathogenic
GRCh37/hg19 4p16.3-11(chr4:68345-49093788)x3 copy number gain See cases [RCV000446451] Chr4:68345..49093788 [GRCh37]
Chr4:4p16.3-11
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p15.32-15.31(chr4:16826659-17818949)x3 copy number gain See cases [RCV000448351] Chr4:16826659..17818949 [GRCh37]
Chr4:4p15.32-15.31
uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q13.1(chr4:68345-66440622)x3 copy number gain See cases [RCV000511193] Chr4:68345..66440622 [GRCh37]
Chr4:4p16.3-q13.1
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-11(chr4:68345-49089361)x3 copy number gain not provided [RCV000682363] Chr4:68345..49089361 [GRCh37]
Chr4:4p16.3-11
pathogenic
GRCh37/hg19 4p16.3-15.1(chr4:4165334-33324781)x1 copy number loss not provided [RCV000682373] Chr4:4165334..33324781 [GRCh37]
Chr4:4p16.3-15.1
pathogenic
GRCh37/hg19 4p15.32-15.31(chr4:16822918-17818885)x3 copy number gain not provided [RCV000743429] Chr4:16822918..17818885 [GRCh37]
Chr4:4p15.32-15.31
benign
GRCh37/hg19 4p15.31(chr4:17812750-17853921)x3 copy number gain not provided [RCV000743432] Chr4:17812750..17853921 [GRCh37]
Chr4:4p15.31
benign
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-11(chr4:1356924-49659859)x3 copy number gain not provided [RCV000743201] Chr4:1356924..49659859 [GRCh37]
Chr4:4p16.3-11
pathogenic
GRCh37/hg19 4p16.3-12(chr4:49450-46339070)x3 copy number gain not provided [RCV000743154] Chr4:49450..46339070 [GRCh37]
Chr4:4p16.3-12
pathogenic
GRCh37/hg19 4p15.33-15.1(chr4:12778849-27760141) copy number loss not provided [RCV000767707] Chr4:12778849..27760141 [GRCh37]
Chr4:4p15.33-15.1
pathogenic
GRCh37/hg19 4p15.33-15.2(chr4:13529798-22750583)x1 copy number loss not provided [RCV000998337] Chr4:13529798..22750583 [GRCh37]
Chr4:4p15.33-15.2
uncertain significance
GRCh37/hg19 4p16.3-15.2(chr4:49450-24280482)x1 copy number loss See cases [RCV001007422] Chr4:49450..24280482 [GRCh37]
Chr4:4p16.3-15.2
pathogenic
GRCh37/hg19 4p16.3-15.2(chr4:68345-27423424)x3 copy number gain not provided [RCV001005510] Chr4:68345..27423424 [GRCh37]
Chr4:4p16.3-15.2
pathogenic
GRCh37/hg19 4p16.3-11(chr4:49450-49620898)x3 copy number gain See cases [RCV001194594] Chr4:49450..49620898 [GRCh37]
Chr4:4p16.3-11
pathogenic
GRCh37/hg19 4p15.32-15.31(chr4:16826786-17818949)x3 copy number gain not provided [RCV001005526] Chr4:16826786..17818949 [GRCh37]
Chr4:4p15.32-15.31
likely benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:24304 AgrOrtholog
COSMIC NCAPG COSMIC
Ensembl Genes ENSG00000109805 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000251496 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000423042 UniProtKB/TrEMBL
  ENSP00000425625 UniProtKB/TrEMBL
Ensembl Transcript ENST00000251496 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000510063 UniProtKB/TrEMBL
  ENST00000514176 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000109805 GTEx
HGNC ID HGNC:24304 ENTREZGENE
Human Proteome Map NCAPG Human Proteome Map
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CND3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cnd3_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:64151 UniProtKB/Swiss-Prot
NCBI Gene 64151 ENTREZGENE
OMIM 606280 OMIM
PANTHER PTHR14418 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cnd3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162397165 PharmGKB
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CND3_HUMAN UniProtKB/Swiss-Prot
  D6RA93_HUMAN UniProtKB/TrEMBL
  H0Y9Z8_HUMAN UniProtKB/TrEMBL
  Q6NUR1_HUMAN UniProtKB/TrEMBL
  Q9BPX3 ENTREZGENE
UniProt Secondary Q3MJE0 UniProtKB/Swiss-Prot
  Q96SV9 UniProtKB/Swiss-Prot
  Q9BUR3 UniProtKB/Swiss-Prot
  Q9BVY1 UniProtKB/Swiss-Prot
  Q9H914 UniProtKB/Swiss-Prot
  Q9H9Z6 UniProtKB/Swiss-Prot
  Q9HBI9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-08 NCAPG  non-SMC condensin I complex subunit G  NCAPG  non-SMC condensin I complex, subunit G  Symbol and/or name change 5135510 APPROVED