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Gene: C11orf80 (chromosome 11 open reading frame 80) Homo sapiens
Symbol: C11orf80
Name: chromosome 11 open reading frame 80
Description: Predicted to be involved in meiotic DNA double-strand break formation and reciprocal meiotic recombination. Predicted to localize to chromosome. Implicated in gestational trophoblastic neoplasm; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; benzo[e]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ22531; HYDM4; putative uncharacterized protein C11orf80; TOP6BL; TOPOVIBL; type 2 DNA topoisomerase 6 subunit B-like; type 2 DNA topoisomerase VI subunit B-like; uncharacterized protein C11orf80
Mus musculus (house mouse) : Gm960 (predicted gene 960)  MGI  Alliance
Rattus norvegicus (Norway rat) : RGD1563323 (similar to hypothetical protein FLJ22531)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102019710 (chromosome unknown open reading frame, human C11orf80)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100981621 (CAAX prenyl protease 2)
Canis lupus familiaris (dog) : C18H11orf80 (chromosome 18 C11orf80 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : CUNH11orf80 (chromosome unknown C11orf80 homolog)
Sus scrofa (pig) : C2H11orf80 (chromosome 2 C11orf80 homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1166,744,451 - 66,843,516 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1166,744,451 - 66,843,328 (+)EnsemblGRCh38hg38GRCh38
GRCh381166,744,736 - 66,843,516 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371166,512,207 - 66,613,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,268,783 - 66,367,375 (+)NCBINCBI36hg18NCBI36
Celera1163,839,232 - 63,954,092 (+)NCBI
Cytogenetic Map11q13.2NCBI
HuRef1162,840,081 - 62,938,914 (+)NCBIHuRef
CHM1_11166,395,778 - 66,494,586 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on C11orf80
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605958
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.