TMEM74 (transmembrane protein 74) - Rat Genome Database

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Gene: TMEM74 (transmembrane protein 74) Homo sapiens
Analyze
Symbol: TMEM74
Name: transmembrane protein 74
RGD ID: 1605858
HGNC Page HGNC
Description: Involved in macroautophagy. Predicted to localize to cytoplasmic vesicle; integral component of membrane; and vacuolar membrane; INTERACTS WITH 5-fluorouracil; aflatoxin B1; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ30668; NET36
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8108,606,850 - 108,787,594 (-)EnsemblGRCh38hg38GRCh38
GRCh388108,606,850 - 108,787,594 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378109,619,079 - 109,799,823 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368109,864,522 - 109,868,946 (-)NCBINCBI36hg18NCBI36
Celera8105,982,575 - 105,986,999 (-)NCBI
Cytogenetic Map8q23.1NCBI
HuRef8105,116,317 - 105,120,741 (-)NCBIHuRef
CHM1_18109,659,332 - 109,839,756 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334   PMID:17207965   PMID:18294959   PMID:24623722   PMID:25416956   PMID:28412412   PMID:29048433   PMID:29629952   PMID:32296183  


Genomics

Comparative Map Data
TMEM74
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8108,606,850 - 108,787,594 (-)EnsemblGRCh38hg38GRCh38
GRCh388108,606,850 - 108,787,594 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378109,619,079 - 109,799,823 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368109,864,522 - 109,868,946 (-)NCBINCBI36hg18NCBI36
Celera8105,982,575 - 105,986,999 (-)NCBI
Cytogenetic Map8q23.1NCBI
HuRef8105,116,317 - 105,120,741 (-)NCBIHuRef
CHM1_18109,659,332 - 109,839,756 (-)NCBICHM1_1
Tmem74
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391543,726,741 - 43,733,462 (-)NCBIGRCm39mm39
GRCm39 Ensembl1543,728,042 - 43,733,432 (-)Ensembl
GRCm381543,863,345 - 43,870,059 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1543,864,646 - 43,870,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv371543,698,241 - 43,701,575 (-)NCBIGRCm37mm9NCBIm37
MGSCv361543,696,769 - 43,700,103 (-)NCBImm8
Celera1544,326,949 - 44,330,313 (-)NCBICelera
Cytogenetic Map15B3.2NCBI
Tmem74
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2774,929,286 - 74,937,973 (-)NCBI
Rnor_6.0 Ensembl782,686,213 - 82,687,130 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0782,684,666 - 82,689,753 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0782,694,142 - 82,699,197 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4779,611,445 - 79,612,413 (-)NCBIRGSC3.4rn4RGSC3.4
Celera771,927,405 - 71,932,481 (-)NCBICelera
Cytogenetic Map7q31NCBI
Tmem74
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541731,328,352 - 31,334,228 (-)NCBIChiLan1.0ChiLan1.0
TMEM74
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18107,583,909 - 107,587,990 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v08105,432,869 - 105,441,542 (-)NCBIMhudiblu_PPA_v0panPan3
TMEM74
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1139,407,005 - 9,415,906 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl139,412,368 - 9,413,285 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha139,383,998 - 9,391,724 (-)NCBI
ROS_Cfam_1.0139,680,515 - 9,688,244 (-)NCBI
UMICH_Zoey_3.1139,423,244 - 9,430,971 (-)NCBI
UNSW_CanFamBas_1.0139,548,243 - 9,555,974 (-)NCBI
UU_Cfam_GSD_1.0139,628,842 - 9,636,571 (-)NCBI
Tmem74
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530328,658,650 - 28,667,449 (+)NCBI
SpeTri2.0NW_00493647036,084,902 - 36,091,517 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM74
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl428,722,273 - 28,731,093 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1428,722,243 - 28,727,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2431,062,896 - 31,067,648 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM74
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18103,604,060 - 103,637,945 (-)NCBI
ChlSab1.1 Ensembl8103,509,309 - 103,510,226 (-)NCBI
Tmem74
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476323,762,204 - 23,765,889 (-)NCBI

Position Markers
RH92459  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378109,795,851 - 109,795,972UniSTSGRCh37
Build 368109,865,027 - 109,865,148RGDNCBI36
Celera8105,983,080 - 105,983,201RGD
Cytogenetic Map8q23.1UniSTS
HuRef8105,116,822 - 105,116,943UniSTS
GeneMap99-GB4 RH Map8447.37UniSTS
BCD2347  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378109,795,441 - 109,795,525UniSTSGRCh37
Build 368109,864,617 - 109,864,701RGDNCBI36
Celera8105,982,670 - 105,982,754RGD
Cytogenetic Map8q23.1UniSTS
HuRef8105,116,412 - 105,116,496UniSTS
GeneMap99-GB4 RH Map8447.59UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:306
Count of miRNA genes:262
Interacting mature miRNAs:275
Transcripts:ENST00000297459, ENST00000518838
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 1 1 3 12 1 1 37
Low 1365 1077 369 175 122 162 1677 1049 2963 41 458 200 18 1 333 1171
Below cutoff 945 1255 1231 429 852 284 2632 1123 754 250 907 1240 152 867 1603 5

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000297459   ⟹   ENSP00000297459
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8108,778,974 - 108,787,594 (-)Ensembl
RefSeq Acc Id: ENST00000518838
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8108,606,850 - 108,787,594 (-)Ensembl
RefSeq Acc Id: NM_153015   ⟹   NP_694560
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388108,778,974 - 108,787,594 (-)NCBI
GRCh378109,791,165 - 109,799,770 (-)NCBI
Build 368109,864,522 - 109,868,946 (-)NCBI Archive
Celera8105,982,575 - 105,986,999 (-)RGD
HuRef8105,116,317 - 105,120,741 (-)RGD
CHM1_18109,831,117 - 109,839,756 (-)NCBI
Sequence:
RefSeq Acc Id: NR_136411
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388108,606,850 - 108,787,594 (-)NCBI
CHM1_18109,659,332 - 109,839,756 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_694560 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH30710 (Get FASTA)   NCBI Sequence Viewer  
  BAB70881 (Get FASTA)   NCBI Sequence Viewer  
  EAW91921 (Get FASTA)   NCBI Sequence Viewer  
  EAW91922 (Get FASTA)   NCBI Sequence Viewer  
  Q96NL1 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_694560   ⟸   NM_153015
- UniProtKB: Q96NL1 (UniProtKB/Swiss-Prot),   A0A024R9D4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000297459   ⟸   ENST00000297459

Promoters
RGD ID:7213989
Promoter ID:EPDNEW_H12740
Type:initiation region
Name:TMEM74_1
Description:transmembrane protein 74
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12741  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388108,787,538 - 108,787,598EPDNEW
RGD ID:6807066
Promoter ID:HG_KWN:61919
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid,   NB4
Transcripts:NM_153015,   UC003YMX.2
Position:
Human AssemblyChrPosition (strand)Source
Build 368109,868,496 - 109,868,996 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q23.1-23.2(chr8:107356178-110913494)x3 copy number gain See cases [RCV000052185] Chr8:107356178..110913494 [GRCh38]
Chr8:108368406..111925723 [GRCh37]
Chr8:108437582..111994899 [NCBI36]
Chr8:8q23.1-23.2
uncertain significance
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
NM_153015.1(TMEM74):c.604G>C (p.Val202Leu) single nucleotide variant Malignant melanoma [RCV000061724] Chr8:108784495 [GRCh38]
Chr8:109796724 [GRCh37]
Chr8:109865900 [NCBI36]
Chr8:8q23.1
not provided
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q21.3-24.23(chr8:86300584-137022587)x3 copy number gain See cases [RCV000135621] Chr8:86300584..137022587 [GRCh38]
Chr8:87312813..138034830 [GRCh37]
Chr8:87381929..138104012 [NCBI36]
Chr8:8q21.3-24.23
pathogenic|likely pathogenic
GRCh38/hg38 8q22.3-23.1(chr8:101171263-109127664)x1 copy number loss See cases [RCV000138134] Chr8:101171263..109127664 [GRCh38]
Chr8:102183491..110139893 [GRCh37]
Chr8:102252667..110209069 [NCBI36]
Chr8:8q22.3-23.1
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:103306336-145068712)x3 copy number gain See cases [RCV000142810] Chr8:103306336..145068712 [GRCh38]
Chr8:104318564..146294098 [GRCh37]
Chr8:104387740..146264902 [NCBI36]
Chr8:8q22.3-24.3
pathogenic|likely pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q23.1-23.2(chr8:109214531-110868812)x3 copy number gain See cases [RCV000446663] Chr8:109214531..110868812 [GRCh37]
Chr8:8q23.1-23.2
uncertain significance
GRCh37/hg19 8q23.1-24.12(chr8:107032887-120742018)x1 copy number loss See cases [RCV000448650] Chr8:107032887..120742018 [GRCh37]
Chr8:8q23.1-24.12
pathogenic
GRCh37/hg19 8q22.1-24.3(chr8:98432250-146222672)x4 copy number gain See cases [RCV000448954] Chr8:98432250..146222672 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.3-24.3(chr8:93047482-141355635)x3 copy number gain See cases [RCV000511761] Chr8:93047482..141355635 [GRCh37]
Chr8:8q21.3-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841154-146295771)x3 copy number gain See cases [RCV000511002] Chr8:86841154..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841228-142689874)x3 copy number gain See cases [RCV000510854] Chr8:86841228..142689874 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3
pathogenic
GRCh37/hg19 8q21.2-23.3(chr8:86841154-116518125)x3 copy number gain not provided [RCV000683045] Chr8:86841154..116518125 [GRCh37]
Chr8:8q21.2-23.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q22.3-23.3(chr8:104437051-114170843)x1 copy number loss not provided [RCV000847013] Chr8:104437051..114170843 [GRCh37]
Chr8:8q22.3-23.3
uncertain significance
GRCh37/hg19 8q23.1(chr8:109694757-110374218)x3 copy number gain not provided [RCV001259024] Chr8:109694757..110374218 [GRCh37]
Chr8:8q23.1
uncertain significance
GRCh37/hg19 8q23.1-24.13(chr8:108421573-123429638)x3 copy number gain not provided [RCV001259025] Chr8:108421573..123429638 [GRCh37]
Chr8:8q23.1-24.13
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:26409 AgrOrtholog
COSMIC TMEM74 COSMIC
Ensembl Genes ENSG00000164841 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000297459 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000297459 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000518838 ENTREZGENE
GTEx ENSG00000164841 GTEx
HGNC ID HGNC:26409 ENTREZGENE
Human Proteome Map TMEM74 Human Proteome Map
InterPro Tmem74 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TMEM74-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:157753 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 157753 ENTREZGENE
OMIM 613935 OMIM
PANTHER PTHR16125 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16125:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142670785 PharmGKB
UniProt A0A024R9D4 ENTREZGENE, UniProtKB/TrEMBL
  Q96NL1 ENTREZGENE, UniProtKB/Swiss-Prot