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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | SPOPL | Human | 1,2-dichloroethane | decreases expression | ISO | Spopl (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of SPOPL mRNA | CTD | PMID:28960355 | SPOPL | Human | 1,2-dimethylhydrazine | decreases expression | ISO | Spopl (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SPOPL mRNA | CTD | PMID:22206623 | SPOPL | Human | 17beta-estradiol | affects expression | ISO | Spopl (Rattus norvegicus) | 6480464 | Estradiol affects the expression of SPOPL mRNA | CTD | PMID:32145629 | SPOPL | Human | 2,2',5,5'-tetrachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:36804509 | SPOPL | Human | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Spopl (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SPOPL mRNA | CTD | PMID:33387578 | SPOPL | Human | 2-hydroxypropanoic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of SPOPL mRNA | CTD | PMID:30851411 | SPOPL | Human | 4-hydroxyphenyl retinamide | increases expression | ISO | Spopl (Mus musculus) | 6480464 | Fenretinide results in increased expression of SPOPL mRNA | CTD | PMID:28973697 | SPOPL | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Spopl (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of SPOPL mRNA | CTD | PMID:30047161 | SPOPL | Human | aflatoxin B1 | increases expression | ISO | Spopl (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of SPOPL mRNA | CTD | PMID:19770486 | SPOPL | Human | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of SPOPL gene | CTD | PMID:27153756 | SPOPL | Human | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of SPOPL mRNA | CTD | PMID:33167477 | SPOPL | Human | amiodarone | increases expression | EXP | | 6480464 | Amiodarone results in increased expression of SPOPL mRNA | CTD | PMID:19774075 | SPOPL | Human | amitrole | decreases expression | ISO | Spopl (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of SPOPL mRNA | CTD | PMID:30047161 | SPOPL | Human | amphetamine | decreases expression | ISO | Spopl (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of SPOPL mRNA | CTD | PMID:30779732 | SPOPL | Human | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of SPOPL mRNA | CTD | PMID:33212167 | SPOPL | Human | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to SPOPL mRNA] | CTD | PMID:32406909 | SPOPL | Human | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of SPOPL mRNA | CTD | PMID:22316170 | SPOPL | Human | benzo[a]pyrene | increases methylation | ISO | Spopl (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of SPOPL 3' UTR more ... | CTD | PMID:27901495 | SPOPL | Human | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of SPOPL 5' UTR and Benzo(a)pyrene affects the methylation of SPOPL promoter | CTD | PMID:27901495 | SPOPL | Human | benzo[a]pyrene diol epoxide I | decreases expression | EXP | | 6480464 | 7 more ... | CTD | PMID:26238291 | SPOPL | Human | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Spopl (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of SPOPL mRNA | CTD | PMID:21318169 | SPOPL | Human | bisphenol A | affects expression | ISO | Spopl (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SPOPL mRNA | CTD | PMID:25181051 | SPOPL | Human | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of SPOPL gene | CTD | PMID:31601247 | SPOPL | Human | bisphenol A | increases expression | ISO | Spopl (Mus musculus) | 6480464 | bisphenol A results in increased expression of SPOPL mRNA | CTD | PMID:33221593 | SPOPL | Human | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SPOPL gene | CTD | PMID:31601247 | SPOPL | Human | bisphenol A | increases expression | ISO | Spopl (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SPOPL mRNA | CTD | PMID:32145629 | SPOPL | Human | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of SPOPL mRNA | CTD | PMID:26079696 | SPOPL | Human | copper(II) sulfate | increases expression | EXP | | 6480464 | Copper Sulfate results in increased expression of SPOPL mRNA | CTD | PMID:19549813 | SPOPL | Human | deguelin | increases expression | EXP | | 6480464 | deguelin results in increased expression of SPOPL mRNA | CTD | PMID:33512557 | SPOPL | Human | Dibutyl phosphate | affects expression | EXP | | 6480464 | di-n-butylphosphoric acid affects the expression of SPOPL mRNA | CTD | PMID:37042841 | SPOPL | Human | fulvestrant | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SPOPL gene | CTD | PMID:31601247 | SPOPL | Human | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of SPOPL mRNA | CTD | PMID:28988120 | SPOPL | Human | methimazole | decreases expression | ISO | Spopl (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of SPOPL mRNA | CTD | PMID:30047161 | SPOPL | Human | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of SPOPL mRNA | CTD | PMID:28001369 | SPOPL | Human | paracetamol | affects expression | ISO | Spopl (Mus musculus) | 6480464 | Acetaminophen affects the expression of SPOPL mRNA | CTD | PMID:17562736 | SPOPL | Human | phenobarbital | affects expression | ISO | Spopl (Mus musculus) | 6480464 | Phenobarbital affects the expression of SPOPL mRNA | CTD | PMID:23091169 | SPOPL | Human | rac-lactic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of SPOPL mRNA | CTD | PMID:30851411 | SPOPL | Human | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SPOPL mRNA | CTD | PMID:23557933 | SPOPL | Human | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SPOPL mRNA | CTD | PMID:33512557 | SPOPL | Human | silver atom | decreases expression | ISO | Spopl (Mus musculus) | 6480464 | Silver results in decreased expression of SPOPL mRNA | CTD | PMID:27131904 | SPOPL | Human | silver(0) | decreases expression | ISO | Spopl (Mus musculus) | 6480464 | Silver results in decreased expression of SPOPL mRNA | CTD | PMID:27131904 | SPOPL | Human | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of SPOPL mRNA | CTD | PMID:38568856 | SPOPL | Human | thioacetamide | increases expression | ISO | Spopl (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of SPOPL mRNA | CTD | PMID:23411599 | SPOPL | Human | thiram | increases expression | EXP | | 6480464 | Thiram results in increased expression of SPOPL mRNA | CTD | PMID:38568856 | SPOPL | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of SPOPL mRNA | CTD | PMID:37042841 | SPOPL | Human | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of SPOPL mRNA | CTD | PMID:25979313 | |