PDIA5 (protein disulfide isomerase family A member 5) - Rat Genome Database

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Gene: PDIA5 (protein disulfide isomerase family A member 5) Homo sapiens
Analyze
Symbol: PDIA5
Name: protein disulfide isomerase family A member 5
RGD ID: 1605694
HGNC Page HGNC:24811
Description: Enables protein disulfide isomerase activity and protein-disulfide reductase activity. Involved in protein folding. Predicted to be located in endoplasmic reticulum lumen and endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FLJ30401; PDIR; protein disulfide isomerase-associated 5; protein disulfide isomerase-related protein; protein disulfide-isomerase A5
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383123,067,025 - 123,162,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3123,067,025 - 123,225,227 (+)EnsemblGRCh38hg38GRCh38
GRCh373122,785,872 - 122,880,951 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363124,268,655 - 124,363,567 (+)NCBINCBI36Build 36hg18NCBI36
Celera3121,192,646 - 121,287,739 (+)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3120,158,749 - 120,254,205 (+)NCBIHuRef
CHM1_13122,749,529 - 122,844,663 (+)NCBICHM1_1
T2T-CHM13v2.03125,787,101 - 125,882,179 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (EXP)
acrylamide  (EXP,ISO)
adefovir pivoxil  (EXP)
amitrole  (ISO)
antimycin A  (EXP)
aristolochic acid A  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (ISO)
bromobenzene  (ISO)
buspirone  (ISO)
cadmium dichloride  (EXP)
captan  (ISO)
carbon nanotube  (ISO)
chloroacetaldehyde  (EXP)
chlorpromazine  (ISO)
cidofovir anhydrous  (EXP)
cisplatin  (EXP)
clodronic acid  (EXP)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (EXP)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (EXP)
diazinon  (EXP)
dioxygen  (EXP)
dorsomorphin  (EXP)
endosulfan  (ISO)
entinostat  (EXP)
fenofibrate  (ISO)
flutamide  (ISO)
folic acid  (ISO)
folpet  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glyphosate  (ISO)
ibuprofen  (ISO)
ifosfamide  (EXP)
ivermectin  (EXP)
ketamine  (ISO)
lithium chloride  (EXP)
menadione  (EXP)
metformin  (ISO)
methoxychlor  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
ozone  (EXP)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (EXP)
pirinixic acid  (ISO)
propiconazole  (ISO)
SB 431542  (EXP)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
thapsigargin  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
Additional References at PubMed
PMID:7556671   PMID:12218051   PMID:12218052   PMID:12477932   PMID:14627699   PMID:14702039   PMID:15644496   PMID:16182193   PMID:16677074   PMID:16712791   PMID:16713569   PMID:17301129  
PMID:17342744   PMID:20379614   PMID:20458450   PMID:20796029   PMID:21873635   PMID:22002444   PMID:22139419   PMID:22190034   PMID:22230366   PMID:22658674   PMID:23206338   PMID:23245351  
PMID:23284306   PMID:23614004   PMID:24037032   PMID:24636989   PMID:24981860   PMID:25416956   PMID:25982273   PMID:26186194   PMID:26344197   PMID:26760575   PMID:27609421   PMID:28514442  
PMID:28611215   PMID:29293453   PMID:30021884   PMID:30196744   PMID:30997501   PMID:32149426   PMID:32296183   PMID:32994395   PMID:33001583   PMID:33022573   PMID:33545068   PMID:33664747  
PMID:33742100   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34597346   PMID:35337019   PMID:35696571   PMID:35748872   PMID:35944360   PMID:36003400   PMID:36168627   PMID:36215168  
PMID:36244648   PMID:36736316   PMID:37931956  


Genomics

Comparative Map Data
PDIA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383123,067,025 - 123,162,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3123,067,025 - 123,225,227 (+)EnsemblGRCh38hg38GRCh38
GRCh373122,785,872 - 122,880,951 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363124,268,655 - 124,363,567 (+)NCBINCBI36Build 36hg18NCBI36
Celera3121,192,646 - 121,287,739 (+)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3120,158,749 - 120,254,205 (+)NCBIHuRef
CHM1_13122,749,529 - 122,844,663 (+)NCBICHM1_1
T2T-CHM13v2.03125,787,101 - 125,882,179 (+)NCBIT2T-CHM13v2.0
Pdia5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,217,678 - 35,311,289 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,217,682 - 35,311,243 (-)EnsemblGRCm39 Ensembl
GRCm381635,397,308 - 35,490,919 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,397,312 - 35,490,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv371635,397,398 - 35,490,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,317,059 - 35,410,620 (-)NCBIMGSCv36mm8
Celera1635,866,403 - 35,959,222 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.37NCBI
Pdia5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,777,436 - 78,892,370 (+)NCBIGRCr8
mRatBN7.21165,272,152 - 65,359,087 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1165,272,155 - 65,359,084 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1174,095,261 - 74,182,045 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,757,523 - 66,844,318 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,788,798 - 65,875,595 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,493,035 - 68,578,999 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,493,035 - 68,578,995 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,580,311 - 71,666,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,117,749 - 67,204,482 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11167,175,337 - 67,262,069 (+)NCBI
Celera1164,733,302 - 64,819,377 (+)NCBICelera
Cytogenetic Map11q22NCBI
Pdia5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542722,268,511 - 22,356,181 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542722,268,730 - 22,356,123 (+)NCBIChiLan1.0ChiLan1.0
PDIA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,012,763 - 121,107,773 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13121,017,569 - 121,112,548 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03120,155,981 - 120,250,961 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13127,059,751 - 127,154,451 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3127,059,751 - 127,154,451 (+)Ensemblpanpan1.1panPan2
PDIA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13326,131,969 - 26,227,256 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3326,131,893 - 26,227,253 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3326,154,925 - 26,249,690 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03326,365,077 - 26,460,503 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3326,364,927 - 26,460,501 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13326,161,419 - 26,256,156 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03326,204,706 - 26,300,729 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,763,803 - 26,858,825 (+)NCBIUU_Cfam_GSD_1.0
Pdia5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602128,116,195 - 128,206,073 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367252,024,643 - 2,114,560 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367252,024,646 - 2,114,530 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDIA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13137,296,883 - 137,398,628 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113137,300,086 - 137,398,465 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213146,843,483 - 146,941,924 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDIA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12257,711,049 - 57,806,058 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2257,711,041 - 57,806,037 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041108,540,265 - 108,633,350 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdia5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249121,408,645 - 1,523,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PDIA5
35 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q13.33-21.2(chr3:121644209-125676353)x1 copy number loss See cases [RCV000051569] Chr3:121644209..125676353 [GRCh38]
Chr3:121363056..125395197 [GRCh37]
Chr3:122845746..126877887 [NCBI36]
Chr3:3q13.33-21.2		 pathogenic
GRCh38/hg38 3q11.1-21.1(chr3:93886671-123216683)x1 copy number loss See cases [RCV000051543] Chr3:93886671..123216683 [GRCh38]
Chr3:93605515..122935530 [GRCh37]
Chr3:95088205..124418220 [NCBI36]
Chr3:3q11.1-21.1		 pathogenic
GRCh38/hg38 3q13.32-21.2(chr3:119117166-125920734)x1 copy number loss See cases [RCV000051546] Chr3:119117166..125920734 [GRCh38]
Chr3:118836013..125639577 [GRCh37]
Chr3:120318703..127122267 [NCBI36]
Chr3:3q13.32-21.2		 pathogenic
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29		 pathogenic
GRCh38/hg38 3q13.2-21.3(chr3:112620977-128734134)x1 copy number loss See cases [RCV000139033] Chr3:112620977..128734134 [GRCh38]
Chr3:112339824..128452977 [GRCh37]
Chr3:113822514..129935667 [NCBI36]
Chr3:3q13.2-21.3		 pathogenic
GRCh38/hg38 3q13.33-21.3(chr3:121925147-126782249)x1 copy number loss See cases [RCV000140814] Chr3:121925147..126782249 [GRCh38]
Chr3:121643994..126501092 [GRCh37]
Chr3:123126684..127983782 [NCBI36]
Chr3:3q13.33-21.3		 pathogenic
GRCh38/hg38 3q13.31-21.2(chr3:114122562-124532374)x1 copy number loss See cases [RCV000142009] Chr3:114122562..124532374 [GRCh38]
Chr3:113841409..124251221 [GRCh37]
Chr3:115324099..125733911 [NCBI36]
Chr3:3q13.31-21.2		 pathogenic
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3 copy number gain See cases [RCV000142340] Chr3:93800620..145695381 [GRCh38]
Chr3:93519464..145413168 [GRCh37]
Chr3:95002154..146895858 [NCBI36]
Chr3:3q11.1-24		 pathogenic
GRCh38/hg38 3q13.32-21.3(chr3:118673898-126540730)x1 copy number loss See cases [RCV000143695] Chr3:118673898..126540730 [GRCh38]
Chr3:118392745..126259573 [GRCh37]
Chr3:119875435..127742263 [NCBI36]
Chr3:3q13.32-21.3		 pathogenic
NM_006810.4(PDIA5):c.1140A>T (p.Gln380His) single nucleotide variant Inborn genetic diseases [RCV003254198] Chr3:123146257 [GRCh38]
Chr3:122865104 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1304A>G (p.His435Arg) single nucleotide variant Inborn genetic diseases [RCV003254682] Chr3:123155001 [GRCh38]
Chr3:122873848 [GRCh37]
Chr3:3q21.1		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_006810.4(PDIA5):c.1516G>A (p.Glu506Lys) single nucleotide variant Inborn genetic diseases [RCV003282728] Chr3:123161916 [GRCh38]
Chr3:122880763 [GRCh37]
Chr3:3q21.1		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3q21.1-21.2(chr3:122698091-125036994)x1 copy number loss not provided [RCV000682303] Chr3:122698091..125036994 [GRCh37]
Chr3:3q21.1-21.2		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
Single allele deletion Deafness-lymphedema-leukemia syndrome [RCV001541924] Chr3:120247726..128319968 [GRCh37]
Chr3:3q13.33-21.3		 pathogenic
GRCh37/hg19 3q21.1(chr3:122772877-122887375)x1 copy number loss not provided [RCV001005465] Chr3:122772877..122887375 [GRCh37]
Chr3:3q21.1		 uncertain significance
GRCh37/hg19 3q21.1(chr3:122823501-123012544)x3 copy number gain not provided [RCV000846198] Chr3:122823501..123012544 [GRCh37]
Chr3:3q21.1		 uncertain significance
GRCh37/hg19 3q21.1(chr3:122827227-123114031)x3 copy number gain not provided [RCV000849730] Chr3:122827227..123114031 [GRCh37]
Chr3:3q21.1		 uncertain significance
GRCh37/hg19 3q13.33-21.1(chr3:121384741-123672180)x3 copy number gain not provided [RCV000848663] Chr3:121384741..123672180 [GRCh37]
Chr3:3q13.33-21.1		 uncertain significance
NM_006810.4(PDIA5):c.1538G>C (p.Gly513Ala) single nucleotide variant Inborn genetic diseases [RCV003271512] Chr3:123161938 [GRCh38]
Chr3:122880785 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1453G>A (p.Ala485Thr) single nucleotide variant Inborn genetic diseases [RCV003251082] Chr3:123161429 [GRCh38]
Chr3:122880276 [GRCh37]
Chr3:3q21.1		 likely benign
NM_006810.4(PDIA5):c.296T>C (p.Val99Ala) single nucleotide variant Inborn genetic diseases [RCV003290836] Chr3:123102449 [GRCh38]
Chr3:122821296 [GRCh37]
Chr3:3q21.1		 uncertain significance
GRCh37/hg19 3q13.31-26.31(chr3:116620308-172042292)x3 copy number gain not provided [RCV002472621] Chr3:116620308..172042292 [GRCh37]
Chr3:3q13.31-26.31		 pathogenic
NC_000003.11:g.(?_120365818)_(133465047_?)del deletion Alkaptonuria [RCV002035459] Chr3:120365818..133465047 [GRCh37]
Chr3:3q13.33-22.1		 pathogenic
NC_000003.11:g.(?_121489192)_(125313644_?)dup duplication Familial hypocalciuric hypercalcemia [RCV003111142] Chr3:121489192..125313644 [GRCh37]
Chr3:3q13.33-21.2		 uncertain significance
Single allele duplication not specified [RCV002286365] Chr3:122157406..123113479 [GRCh38]
Chr3:3q13.33-21.1		 uncertain significance
NM_006810.4(PDIA5):c.1157C>T (p.Pro386Leu) single nucleotide variant Inborn genetic diseases [RCV002686466] Chr3:123150248 [GRCh38]
Chr3:122869095 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1301C>T (p.Pro434Leu) single nucleotide variant Inborn genetic diseases [RCV003012867] Chr3:123154998 [GRCh38]
Chr3:122873845 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1003G>C (p.Val335Leu) single nucleotide variant Inborn genetic diseases [RCV002798098] Chr3:123146120 [GRCh38]
Chr3:122864967 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.55T>C (p.Ser19Pro) single nucleotide variant Inborn genetic diseases [RCV002884228] Chr3:123089180 [GRCh38]
Chr3:122808027 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.799C>T (p.Pro267Ser) single nucleotide variant Inborn genetic diseases [RCV002845949] Chr3:123130505 [GRCh38]
Chr3:122849352 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1453G>T (p.Ala485Ser) single nucleotide variant Inborn genetic diseases [RCV003004328] Chr3:123161429 [GRCh38]
Chr3:122880276 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.137G>A (p.Arg46Gln) single nucleotide variant Inborn genetic diseases [RCV002891807] Chr3:123089262 [GRCh38]
Chr3:122808109 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.235A>G (p.Thr79Ala) single nucleotide variant Inborn genetic diseases [RCV002954727] Chr3:123092420 [GRCh38]
Chr3:122811267 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.385A>G (p.Lys129Glu) single nucleotide variant Inborn genetic diseases [RCV002964866] Chr3:123102794 [GRCh38]
Chr3:122821641 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.536C>T (p.Ala179Val) single nucleotide variant Inborn genetic diseases [RCV002963722] Chr3:123110999 [GRCh38]
Chr3:122829846 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.691T>A (p.Cys231Ser) single nucleotide variant Inborn genetic diseases [RCV002961679] Chr3:123124147 [GRCh38]
Chr3:122842994 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.377T>C (p.Val126Ala) single nucleotide variant Inborn genetic diseases [RCV002668944] Chr3:123102786 [GRCh38]
Chr3:122821633 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.472A>G (p.Ser158Gly) single nucleotide variant Inborn genetic diseases [RCV002748058] Chr3:123106833 [GRCh38]
Chr3:122825680 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.847G>A (p.Asp283Asn) single nucleotide variant Inborn genetic diseases [RCV003183225] Chr3:123130553 [GRCh38]
Chr3:122849400 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1162C>A (p.Pro388Thr) single nucleotide variant Inborn genetic diseases [RCV003175876] Chr3:123150253 [GRCh38]
Chr3:122869100 [GRCh37]
Chr3:3q21.1		 uncertain significance
GRCh38/hg38 3q11.1-21.2(chr3:93979547-124774010)x1 copy number loss Chromosome 3q13.31 deletion syndrome [RCV003327614] Chr3:93979547..124774010 [GRCh38]
Chr3:3q11.1-21.2		 pathogenic
NM_006810.4(PDIA5):c.826G>A (p.Gly276Ser) single nucleotide variant Inborn genetic diseases [RCV003359463] Chr3:123130532 [GRCh38]
Chr3:122849379 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1000G>C (p.Ala334Pro) single nucleotide variant Inborn genetic diseases [RCV003379352] Chr3:123146117 [GRCh38]
Chr3:122864964 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.1345A>G (p.Ile449Val) single nucleotide variant Inborn genetic diseases [RCV003362486] Chr3:123161321 [GRCh38]
Chr3:122880168 [GRCh37]
Chr3:3q21.1		 uncertain significance
NM_006810.4(PDIA5):c.685A>G (p.Thr229Ala) single nucleotide variant Inborn genetic diseases [RCV003342065] Chr3:123124141 [GRCh38]
Chr3:122842988 [GRCh37]
Chr3:3q21.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1930
Count of miRNA genes:947
Interacting mature miRNAs:1171
Transcripts:ENST00000316218, ENST00000467157, ENST00000469649, ENST00000472319, ENST00000484644, ENST00000485208, ENST00000489923, ENST00000495004
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D3S3645  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373122,791,718 - 122,791,911UniSTSGRCh37
Build 363124,274,408 - 124,274,601RGDNCBI36
Celera3121,198,508 - 121,198,701RGD
Cytogenetic Map3q21.1UniSTS
HuRef3120,164,611 - 120,164,802UniSTS
Marshfield Genetic Map3140.19RGD
Marshfield Genetic Map3140.19UniSTS
Genethon Genetic Map3141.1UniSTS
Whitehead-YAC Contig Map3 UniSTS
SHGC-80611  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373122,834,773 - 122,835,106UniSTSGRCh37
Build 363124,317,463 - 124,317,796RGDNCBI36
Celera3121,241,569 - 121,241,902RGD
Cytogenetic Map3q21.1UniSTS
HuRef3120,207,648 - 120,207,981UniSTS
TNG Radiation Hybrid Map368676.0UniSTS
SHGC-79570  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373122,861,219 - 122,861,497UniSTSGRCh37
Build 363124,343,909 - 124,344,187RGDNCBI36
Celera3121,268,039 - 121,268,317RGD
Cytogenetic Map3q21.1UniSTS
HuRef3120,234,113 - 120,234,391UniSTS
TNG Radiation Hybrid Map368700.0UniSTS
TNG Radiation Hybrid Map368692.0UniSTS
SHGC-111245  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373122,805,624 - 122,805,900UniSTSGRCh37
Build 363124,288,314 - 124,288,590RGDNCBI36
Celera3121,212,414 - 121,212,690RGD
Cytogenetic Map3q21.1UniSTS
HuRef3120,178,515 - 120,178,791UniSTS
TNG Radiation Hybrid Map368673.0UniSTS
SHGC-150764  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373122,791,621 - 122,791,822UniSTSGRCh37
Build 363124,274,311 - 124,274,512RGDNCBI36
Celera3121,198,411 - 121,198,612RGD
Cytogenetic Map3q21.1UniSTS
HuRef3120,164,514 - 120,164,713UniSTS
TNG Radiation Hybrid Map368663.0UniSTS
sY3084  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q22.12UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map6q22.33UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map7q11.2UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map18q22.1UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map12q21.33UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map3q25UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map1q42.11UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map4q27UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map18q12.1-q21.1UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map14q22UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map1p35.3-p33UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map14q24UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map15q15-q21.1UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map18p11.3-p11.2UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map6p22.3-p22.1UniSTS
Cytogenetic Map10q22.3UniSTS
Cytogenetic Map1p36.11-p34.2UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map1q42.1-q43UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map6q27UniSTS
Cytogenetic Map22q13.31UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map13q13.3UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapXq21.3UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map1p36.22UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map4p16UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map18p11.22UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map13q32.1UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map22q13.1-q13.2UniSTS
Cytogenetic Map7p15UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map15q26.2UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map8q13UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map3q21.1UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map14q32.1UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map3q12.3UniSTS
RH71326  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373122,880,266 - 122,880,830UniSTSGRCh37
Celera3121,287,052 - 121,287,616UniSTS
Cytogenetic Map3q21.1UniSTS
HuRef3120,253,518 - 120,254,082UniSTS
GeneMap99-GB4 RH Map3432.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1712 1335 1688 579 843 450 2623 549 992 284 1305 1582 142 1 934 1557 6 2
Low 727 1631 38 45 1067 15 1734 1646 2393 135 155 31 33 270 1231
Below cutoff 25 37 2 349

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_006810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_028444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_427359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_427360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC083797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM549365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA414869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB158962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D49490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF457675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000316218   ⟹   ENSP00000323313
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,067,025 - 123,162,104 (+)Ensembl
RefSeq Acc Id: ENST00000467157
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,144,507 - 123,162,103 (+)Ensembl
RefSeq Acc Id: ENST00000469649   ⟹   ENSP00000417199
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,150,339 - 123,225,227 (+)Ensembl
RefSeq Acc Id: ENST00000472319
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,124,066 - 123,146,258 (+)Ensembl
RefSeq Acc Id: ENST00000484644   ⟹   ENSP00000419946
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,067,348 - 123,106,842 (+)Ensembl
RefSeq Acc Id: ENST00000485208
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,144,676 - 123,150,365 (+)Ensembl
RefSeq Acc Id: ENST00000489923   ⟹   ENSP00000417520
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,067,062 - 123,162,104 (+)Ensembl
RefSeq Acc Id: ENST00000495004
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3123,089,107 - 123,111,007 (+)Ensembl
RefSeq Acc Id: NM_006810   ⟹   NP_006801
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383123,067,025 - 123,162,104 (+)NCBI
GRCh373122,785,856 - 122,880,953 (+)RGD
Build 363124,268,655 - 124,363,567 (+)NCBI Archive
Celera3121,192,646 - 121,287,739 (+)RGD
HuRef3120,158,749 - 120,254,205 (+)ENTREZGENE
CHM1_13122,749,529 - 122,844,663 (+)NCBI
T2T-CHM13v2.03125,787,101 - 125,882,179 (+)NCBI
Sequence:
RefSeq Acc Id: NR_028444
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383123,067,025 - 123,162,104 (+)NCBI
GRCh373122,785,856 - 122,880,953 (+)RGD
Celera3121,192,646 - 121,287,739 (+)RGD
HuRef3120,158,749 - 120,254,205 (+)ENTREZGENE
CHM1_13122,749,529 - 122,844,663 (+)NCBI
T2T-CHM13v2.03125,787,101 - 125,882,179 (+)NCBI
Sequence:
RefSeq Acc Id: XR_007095629
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383123,067,025 - 123,150,341 (+)NCBI
RefSeq Acc Id: XR_007095630
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383123,067,025 - 123,146,149 (+)NCBI
RefSeq Acc Id: XR_008486636
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03125,787,101 - 125,870,450 (+)NCBI
RefSeq Acc Id: XR_008486637
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03125,787,101 - 125,866,259 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_006801   ⟸   NM_006810
- Peptide Label: precursor
- UniProtKB: D3DN95 (UniProtKB/Swiss-Prot),   Q9BV43 (UniProtKB/Swiss-Prot),   Q14554 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000417199   ⟸   ENST00000469649
RefSeq Acc Id: ENSP00000419946   ⟸   ENST00000484644
RefSeq Acc Id: ENSP00000323313   ⟸   ENST00000316218
RefSeq Acc Id: ENSP00000417520   ⟸   ENST00000489923
Protein Domains
Thioredoxin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q14554-F1-model_v2 AlphaFold Q14554 1-519 view protein structure

Promoters
RGD ID:6865464
Promoter ID:EPDNEW_H5897
Type:initiation region
Name:PDIA5_1
Description:protein disulfide isomerase family A member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383123,067,025 - 123,067,085EPDNEW
RGD ID:6800902
Promoter ID:HG_KWN:46005
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000393573,   NM_006810,   NR_028444
Position:
Human AssemblyChrPosition (strand)Source
Build 363124,268,381 - 124,268,881 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:24811 AgrOrtholog
COSMIC PDIA5 COSMIC
Ensembl Genes ENSG00000065485 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000316218 ENTREZGENE
  ENST00000316218.12 UniProtKB/Swiss-Prot
  ENST00000469649.1 UniProtKB/TrEMBL
  ENST00000484644.5 UniProtKB/TrEMBL
  ENST00000489923 ENTREZGENE
  ENST00000489923.5 UniProtKB/Swiss-Prot
Gene3D-CATH Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000065485 GTEx
HGNC ID HGNC:24811 ENTREZGENE
Human Proteome Map PDIA5 Human Proteome Map
InterPro PDI_a_PDIR UniProtKB/Swiss-Prot
  PDIA5_N_PDI_b UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10954 UniProtKB/Swiss-Prot
NCBI Gene 10954 ENTREZGENE
OMIM 616942 OMIM
PANTHER PROTEIN DISULFIDE-ISOMERASE A5 UniProtKB/Swiss-Prot
  PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 UniProtKB/TrEMBL
Pfam Thioredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142671191 PharmGKB
PRINTS THIOREDOXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ER_TARGET UniProtKB/Swiss-Prot
  THIOREDOXIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt C9JY10_HUMAN UniProtKB/TrEMBL
  D3DN95 ENTREZGENE
  H7C4F9_HUMAN UniProtKB/TrEMBL
  PDIA5_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q9BV43 ENTREZGENE
UniProt Secondary D3DN95 UniProtKB/Swiss-Prot
  Q9BV43 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 PDIA5  protein disulfide isomerase family A member 5    protein disulfide isomerase family A, member 5  Symbol and/or name change 5135510 APPROVED