PRSS50 (serine protease 50) - Rat Genome Database

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Gene: PRSS50 (serine protease 50) Homo sapiens
Analyze
Symbol: PRSS50
Name: serine protease 50
RGD ID: 1605685
HGNC Page HGNC:17910
Description: Enables threonine-type endopeptidase activity. Involved in proteolysis. Located in endoplasmic reticulum.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cancer/testis antigen 20; CT20; probable threonine protease PRSS50; protease, serine 50; protease, serine, 50; testes specific protease 50; testes-specific protease 50; testicular tissue protein Li 210; testis-specific protease-like protein 50; TSP50
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,712,117 - 46,717,869 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,712,117 - 46,717,869 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,753,607 - 46,759,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,728,610 - 46,734,368 (-)NCBINCBI36Build 36hg18NCBI36
Celera346,692,302 - 46,698,069 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,796,456 - 46,802,223 (-)NCBIHuRef
CHM1_1346,703,722 - 46,709,489 (-)NCBICHM1_1
T2T-CHM13v2.0346,728,202 - 46,733,954 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IDA,IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10397268   PMID:11782390   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15491742   PMID:17283160   PMID:18462069   PMID:18662669   PMID:20506264   PMID:21765952   PMID:21873635  
PMID:22574111   PMID:25049081   PMID:25077921   PMID:25312478   PMID:25399078   PMID:25640309   PMID:25811800   PMID:26186194   PMID:27039397   PMID:27109614   PMID:28514442   PMID:28631709  
PMID:28650473   PMID:29361914   PMID:33630390   PMID:33956530   PMID:33961781   PMID:34016961   PMID:34744521   PMID:36724073  


Genomics

Comparative Map Data
PRSS50
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,712,117 - 46,717,869 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,712,117 - 46,717,869 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,753,607 - 46,759,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,728,610 - 46,734,368 (-)NCBINCBI36Build 36hg18NCBI36
Celera346,692,302 - 46,698,069 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,796,456 - 46,802,223 (-)NCBIHuRef
CHM1_1346,703,722 - 46,709,489 (-)NCBICHM1_1
T2T-CHM13v2.0346,728,202 - 46,733,954 (-)NCBIT2T-CHM13v2.0
Prss50
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,687,032 - 110,693,697 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,687,035 - 110,693,697 (+)EnsemblGRCm39 Ensembl
GRCm389110,857,964 - 110,864,629 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,857,967 - 110,864,629 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,760,471 - 110,767,132 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369111,964,631 - 111,971,369 (+)NCBIMGSCv36mm8
MGSCv369110,702,783 - 110,709,444 (+)NCBIMGSCv36mm8
Celera9110,589,938 - 110,590,855 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
Prss50
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,719,574 - 119,727,269 (+)NCBIGRCr8
mRatBN7.28110,842,525 - 110,848,855 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,842,671 - 110,848,802 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.08119,134,966 - 119,141,255 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,135,013 - 119,141,150 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,473,353 - 118,479,663 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8110,125,130 - 110,131,417 (+)NCBICelera
Cytogenetic Map8q32NCBI
Prss50
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542025,424,082 - 25,427,705 (+)NCBIChiLan1.0ChiLan1.0
PRSS50
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,667,914 - 46,674,227 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,672,684 - 46,678,997 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,610,119 - 46,616,435 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,713,568 - 47,719,706 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,713,699 - 47,719,315 (-)Ensemblpanpan1.1panPan2
PRSS50
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,046,177 - 42,051,517 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,962,573 - 41,967,707 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,528,974 - 42,534,105 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,528,989 - 42,534,105 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,770,289 - 41,775,396 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,171,301 - 42,176,453 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,452,345 - 42,457,480 (+)NCBIUU_Cfam_GSD_1.0
Prss50
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,992,631 - 200,998,921 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936596541,918 - 546,364 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936596541,918 - 544,866 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRSS50
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,632,886 - 29,639,045 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,633,575 - 29,638,994 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,030,971 - 33,036,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103227551
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,135,011 - 8,142,455 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,135,046 - 8,140,809 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,009,233 - 159,015,033 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prss50
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473074,494,152 - 74,497,473 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PRSS50
21 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_147196.2(TMIE):c.331C>T (p.Pro111Ser) single nucleotide variant Malignant melanoma [RCV000066090] Chr3:46709245 [GRCh38]
Chr3:46750735 [GRCh37]
Chr3:46725739 [NCBI36]
Chr3:3p21.31
not provided
GRCh38/hg38 3p21.31-21.2(chr3:45879883-50749922)x4 copy number gain See cases [RCV000133650] Chr3:45879883..50749922 [GRCh38]
Chr3:45921375..50787353 [GRCh37]
Chr3:45896379..50762357 [NCBI36]
Chr3:3p21.31-21.2
pathogenic
GRCh37/hg19 3p22.2-21.31(chr3:37028313-49929220)x3 copy number gain See cases [RCV000240519] Chr3:37028313..49929220 [GRCh37]
Chr3:3p22.2-21.31
likely pathogenic
NM_013270.5(PRSS50):c.416C>T (p.Ala139Val) single nucleotide variant Inborn genetic diseases [RCV003295280] Chr3:46715589 [GRCh38]
Chr3:46757079 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.143C>G (p.Ser48Cys) single nucleotide variant Inborn genetic diseases [RCV003274960] Chr3:46717601 [GRCh38]
Chr3:46759091 [GRCh37]
Chr3:3p21.31
uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
NM_013270.5(PRSS50):c.44G>A (p.Arg15Gln) single nucleotide variant Inborn genetic diseases [RCV003241684] Chr3:46717781 [GRCh38]
Chr3:46759271 [GRCh37]
Chr3:3p21.31
uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p21.31(chr3:46728659-46753976)x1 copy number loss not provided [RCV000742389] Chr3:46728659..46753976 [GRCh37]
Chr3:3p21.31
benign
GRCh37/hg19 3p21.31-21.1(chr3:45153770-53878616) copy number gain not provided [RCV000767704] Chr3:45153770..53878616 [GRCh37]
Chr3:3p21.31-21.1
pathogenic
NM_013270.5(PRSS50):c.292G>A (p.Val98Ile) single nucleotide variant not provided [RCV000964908] Chr3:46717452 [GRCh38]
Chr3:46758942 [GRCh37]
Chr3:3p21.31
benign
NM_013270.5(PRSS50):c.715C>T (p.Arg239Cys) single nucleotide variant not provided [RCV000884423] Chr3:46714257 [GRCh38]
Chr3:46755747 [GRCh37]
Chr3:3p21.31
benign
NM_013270.5(PRSS50):c.890C>T (p.Ala297Val) single nucleotide variant Inborn genetic diseases [RCV003251112] Chr3:46712932 [GRCh38]
Chr3:46754422 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.688A>G (p.Thr230Ala) single nucleotide variant Inborn genetic diseases [RCV003272573] Chr3:46714284 [GRCh38]
Chr3:46755774 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.622G>A (p.Gly208Ser) single nucleotide variant Inborn genetic diseases [RCV003294908] Chr3:46714350 [GRCh38]
Chr3:46755840 [GRCh37]
Chr3:3p21.31
uncertain significance
GRCh37/hg19 3p21.31(chr3:46656350-46990919)x3 copy number gain not provided [RCV001005430] Chr3:46656350..46990919 [GRCh37]
Chr3:3p21.31
uncertain significance
NC_000003.11:g.(?_45435946)_(49137751_?)dup duplication Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome [RCV003116297] Chr3:45435946..49137751 [GRCh37]
Chr3:3p21.31
uncertain significance
GRCh37/hg19 3p21.31(chr3:44948482-49115809)x1 copy number loss not provided [RCV002279744] Chr3:44948482..49115809 [GRCh37]
Chr3:3p21.31
pathogenic
NM_013270.5(PRSS50):c.773G>A (p.Arg258Gln) single nucleotide variant Inborn genetic diseases [RCV002992765] Chr3:46713049 [GRCh38]
Chr3:46754539 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.253A>G (p.Thr85Ala) single nucleotide variant Inborn genetic diseases [RCV002729238] Chr3:46717491 [GRCh38]
Chr3:46758981 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.883A>G (p.Met295Val) single nucleotide variant Inborn genetic diseases [RCV002732054] Chr3:46712939 [GRCh38]
Chr3:46754429 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.667C>T (p.Arg223Trp) single nucleotide variant Inborn genetic diseases [RCV002737390] Chr3:46714305 [GRCh38]
Chr3:46755795 [GRCh37]
Chr3:3p21.31
likely benign
NM_013270.5(PRSS50):c.689C>T (p.Thr230Met) single nucleotide variant Inborn genetic diseases [RCV003001230] Chr3:46714283 [GRCh38]
Chr3:46755773 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.691G>A (p.Asp231Asn) single nucleotide variant Inborn genetic diseases [RCV002925804] Chr3:46714281 [GRCh38]
Chr3:46755771 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.807C>G (p.Asn269Lys) single nucleotide variant Inborn genetic diseases [RCV002917149] Chr3:46713015 [GRCh38]
Chr3:46754505 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.365G>C (p.Arg122Pro) single nucleotide variant Inborn genetic diseases [RCV002955445] Chr3:46715640 [GRCh38]
Chr3:46757130 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.524C>T (p.Thr175Met) single nucleotide variant Inborn genetic diseases [RCV002965884] Chr3:46714448 [GRCh38]
Chr3:46755938 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.1124T>A (p.Leu375His) single nucleotide variant Inborn genetic diseases [RCV002678999] Chr3:46712280 [GRCh38]
Chr3:46753770 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.185A>G (p.Lys62Arg) single nucleotide variant Inborn genetic diseases [RCV002724128] Chr3:46717559 [GRCh38]
Chr3:46759049 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.716G>A (p.Arg239His) single nucleotide variant Inborn genetic diseases [RCV003259683] Chr3:46714256 [GRCh38]
Chr3:46755746 [GRCh37]
Chr3:3p21.31
uncertain significance
NM_013270.5(PRSS50):c.251C>T (p.Ser84Leu) single nucleotide variant Inborn genetic diseases [RCV003308837] Chr3:46717493 [GRCh38]
Chr3:46758983 [GRCh37]
Chr3:3p21.31
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:648
Count of miRNA genes:301
Interacting mature miRNAs:324
Transcripts:ENST00000315170, ENST00000460241
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system appendage entire extraembryonic component
High
Medium 12 2 2 3 67 20
Low 12 5 173 131 42 131 183 9 58 121 134 127 1
Below cutoff 60 12 76 68 193 70 47 27 63 132 76 108 3 1 3

Sequence


RefSeq Acc Id: ENST00000315170   ⟹   ENSP00000326598
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl346,712,117 - 46,717,869 (-)Ensembl
RefSeq Acc Id: ENST00000460241   ⟹   ENSP00000418875
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl346,712,115 - 46,812,574 (-)Ensembl
RefSeq Acc Id: NM_013270   ⟹   NP_037402
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38346,712,117 - 46,717,869 (-)NCBI
GRCh37346,753,606 - 46,759,373 (-)RGD
Build 36346,728,610 - 46,734,368 (-)NCBI Archive
Celera346,692,302 - 46,698,069 (-)RGD
HuRef346,796,456 - 46,802,223 (-)ENTREZGENE
CHM1_1346,703,722 - 46,709,489 (-)NCBI
T2T-CHM13v2.0346,728,202 - 46,733,954 (-)NCBI
Sequence:
RefSeq Acc Id: NP_037402   ⟸   NM_013270
- Peptide Label: precursor
- UniProtKB: Q9UI38 (UniProtKB/Swiss-Prot),   A0A140VJY3 (UniProtKB/TrEMBL),   B3KS16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000326598   ⟸   ENST00000315170
RefSeq Acc Id: ENSP00000418875   ⟸   ENST00000460241
Protein Domains
Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UI38-F1-model_v2 AlphaFold Q9UI38 1-385 view protein structure

Promoters
RGD ID:6864224
Promoter ID:EPDNEW_H5277
Type:initiation region
Name:PRSS50_1
Description:protease, serine 50
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5278  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38346,717,843 - 46,717,903EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:17910 AgrOrtholog
COSMIC PRSS50 COSMIC
Ensembl Genes ENSG00000206549 Ensembl
  ENSG00000283706 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000315170 ENTREZGENE
  ENST00000315170.13 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000206549 GTEx
  ENSG00000283706 GTEx
HGNC ID HGNC:17910 ENTREZGENE
Human Proteome Map PRSS50 Human Proteome Map
InterPro Peptidase_S1_PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:29122 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 29122 ENTREZGENE
OMIM 607950 OMIM
PANTHER SERINE PROTEASE 44-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPTASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA165698443 PharmGKB
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140VJY3 ENTREZGENE, UniProtKB/TrEMBL
  B3KS16 ENTREZGENE, UniProtKB/TrEMBL
  Q9UI38 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-23 PRSS50  serine protease 50    protease, serine 50  Symbol and/or name change 5135510 APPROVED
2015-11-17 PRSS50  protease, serine 50    protease, serine, 50  Symbol and/or name change 5135510 APPROVED
2011-07-27 PRSS50  protease, serine, 50  TSP50  testes-specific protease 50  Symbol and/or name change 5135510 APPROVED