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Gene: NKX6-3 (NK6 homeobox 3) Homo sapiens
Symbol: NKX6-3
Name: NK6 homeobox 3
Description: Exhibits sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ25169; homeobox protein Nkx-6.3; NK6 transcription factor related, locus 3; NKX6.3
Mus musculus (house mouse) : Nkx6-3 (NK6 homeobox 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nkx6-3 (NK6 homeobox 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx6-3 (NK6 homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX6-3 (NK6 homeobox 3)
Canis lupus familiaris (dog) : NKX6-3 (NK6 homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx6-3 (NK6 homeobox 3)
Sus scrofa (pig) : NKX6-3 (NK6 homeobox 3)
Chlorocebus sabaeus (green monkey) : NKX6-3 (NK6 homeobox 3)
Heterocephalus glaber (naked mole-rat) : Nkx6-3 (NK6 homeobox 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl841,645,177 - 41,650,817 (-)Ensembl
GRCh38841,645,177 - 41,650,817 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37841,503,829 - 41,508,011 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36841,622,986 - 41,624,035 (-)NCBINCBI36hg18NCBI36
Celera840,452,355 - 40,453,402 (-)NCBI
Cytogenetic Map8p11.21NCBI
HuRef840,031,601 - 40,032,605 (-)NCBIHuRef
CHM1_1841,550,905 - 41,553,080 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NKX6-3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605569
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.