H4C15 (H4 clustered histone 15) - Rat Genome Database

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Gene: H4C15 (H4 clustered histone 15) Homo sapiens
Analyze
Symbol: H4C15
Name: H4 clustered histone 15
RGD ID: 1605451
HGNC Page HGNC:29607
Description: A structural constituent of chromatin. Involved in negative regulation of megakaryocyte differentiation and nucleosome assembly. Located in CENP-A containing nucleosome and nucleus. Part of nucleosome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: H4-16; H4/o; H4C1; H4C11; H4C12; H4C13; H4C14; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; HIST2H4A; HIST2H4B; HIST4H4; histone 2, H4b; histone cluster 2 H4 family member b; histone cluster 2, H4b; histone H4
RGD Orthologs
Mouse
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381149,844,488 - 149,861,240 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1149,854,045 - 149,861,159 (-)EnsemblGRCh38hg38GRCh38
GRCh371149,825,657 - 149,832,725 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,098,954 - 148,099,349 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map1q21.2NCBI
HuRef1121,186,931 - 121,187,326 (+)NCBIHuRef
CHM1_11151,228,890 - 151,229,285 (-)NCBICHM1_1
T2T-CHM13v2.01148,978,230 - 148,985,386 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3035717   PMID:6494913   PMID:9540062   PMID:10220385   PMID:12408966   PMID:12477932   PMID:12556504   PMID:14585971   PMID:14718166   PMID:15161933   PMID:15504738   PMID:15527963  
PMID:15670829   PMID:15823041   PMID:15933069   PMID:16131487   PMID:16166375   PMID:16415788   PMID:16917504   PMID:17540172   PMID:17666011   PMID:17675446   PMID:18029348   PMID:18404153  
PMID:18408754   PMID:18474616   PMID:18571423   PMID:19135898   PMID:19199708   PMID:19249677   PMID:19410544   PMID:19494831   PMID:19498464   PMID:19710015   PMID:19738201   PMID:19862764  
PMID:19946888   PMID:20000738   PMID:20224553   PMID:20458337   PMID:20462248   PMID:20498094   PMID:20618440   PMID:20709061   PMID:20739937   PMID:20951943   PMID:21081503   PMID:21085121  
PMID:21145461   PMID:21164480   PMID:21478274   PMID:21596426   PMID:21630459   PMID:21636898   PMID:21743476   PMID:21800051   PMID:21812398   PMID:21873635   PMID:21888893   PMID:21907836  
PMID:21983900   PMID:22145905   PMID:22268729   PMID:22343720   PMID:22368283   PMID:22373579   PMID:22615379   PMID:22623428   PMID:22658674   PMID:22681889   PMID:23071334   PMID:23075851  
PMID:23142979   PMID:23376485   PMID:23377543   PMID:23533145   PMID:23760478   PMID:23831576   PMID:23979707   PMID:24183680   PMID:24311584   PMID:24360279   PMID:24361270   PMID:24525235  
PMID:24596249   PMID:24625528   PMID:24699735   PMID:24711643   PMID:24726341   PMID:24981860   PMID:25281266   PMID:25332235   PMID:25362550   PMID:25416956   PMID:25556234   PMID:25579814  
PMID:25615412   PMID:25619998   PMID:25651062   PMID:25910212   PMID:25963833   PMID:26167883   PMID:26496610   PMID:26694698   PMID:26725010   PMID:26912361   PMID:27153538   PMID:27248496  
PMID:28514442   PMID:28718761   PMID:28902428   PMID:28977666   PMID:28986522   PMID:29676528   PMID:29844126   PMID:30021884   PMID:30209976   PMID:30554943   PMID:31142837   PMID:31353912  
PMID:31759698   PMID:31790919   PMID:32296183   PMID:32814053   PMID:33857403   PMID:34079125   PMID:34373451   PMID:36180920  


Genomics

Comparative Map Data
H4C15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381149,844,488 - 149,861,240 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1149,854,045 - 149,861,159 (-)EnsemblGRCh38hg38GRCh38
GRCh371149,825,657 - 149,832,725 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,098,954 - 148,099,349 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map1q21.2NCBI
HuRef1121,186,931 - 121,187,326 (+)NCBIHuRef
CHM1_11151,228,890 - 151,229,285 (-)NCBICHM1_1
T2T-CHM13v2.01148,978,230 - 148,985,386 (-)NCBIT2T-CHM13v2.0
H4c4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391323,765,551 - 23,765,952 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1323,765,581 - 23,766,718 (+)EnsemblGRCm39 Ensembl
GRCm381323,581,568 - 23,581,969 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1323,581,598 - 23,582,735 (+)EnsemblGRCm38mm10GRCm38
MGSCv371323,673,471 - 23,673,782 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361323,589,067 - 23,589,378 (+)NCBIMGSCv36mm8
Celera1323,813,517 - 23,813,828 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map139.8NCBI
LOC117975185
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,973,296 - 99,979,666 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,733,575 - 99,740,536 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01125,196,600 - 125,205,588 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC101966143
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,135,229 - 21,144,866 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936580173,731 - 175,254 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
H4C3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1720,773,579 - 20,773,986 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103247796
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1114,670,283 - 14,670,591 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603813,437,077 - 13,441,544 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q21.2-25.2(chr1:149854269-180267197)x3 copy number gain See cases [RCV000143515] Chr1:149854269..180267197 [GRCh38]
Chr1:149825831..180236332 [GRCh37]
Chr1:148092455..178502955 [NCBI36]
Chr1:1q21.2-25.2		 pathogenic
GRCh37/hg19 1q21.2(chr1:149783688-150049029)x3 copy number gain Breast ductal adenocarcinoma [RCV000207055] Chr1:149783688..150049029 [GRCh37]
Chr1:1q21.2		 uncertain significance
GRCh37/hg19 1q21.1-21.3(chr1:144927578-153223600)x3 copy number gain Chromosome 1q21.1 duplication syndrome [RCV000223957] Chr1:144927578..153223600 [GRCh37]
Chr1:1q21.1-21.3		 pathogenic
GRCh37/hg19 1q21.1-21.3(chr1:143753740-151399970)x3 copy number gain See cases [RCV000447109] Chr1:143753740..151399970 [GRCh37]
Chr1:1q21.1-21.3		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1q21.2(chr1:149802401-149944241)x3 copy number gain not provided [RCV000684654] Chr1:149802401..149944241 [GRCh37]
Chr1:1q21.2		 uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1q21.2(chr1:149789016-149835093)x1 copy number loss not provided [RCV000749184] Chr1:149789016..149835093 [GRCh37]
Chr1:1q21.2		 benign
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44		 uncertain significance
GRCh37/hg19 1q12-23.1(chr1:142535935-157648813)x3 copy number gain Chromosome 1q21.1 duplication syndrome [RCV003329522] Chr1:142535935..157648813 [GRCh37]
Chr1:1q12-23.1		 pathogenic
GRCh37/hg19 1q21.1-23.1(chr1:144368497-158992086)x3 copy number gain not specified [RCV003986717] Chr1:144368497..158992086 [GRCh37]
Chr1:1q21.1-23.1		 pathogenic
GRCh37/hg19 1q21.2-21.3(chr1:149713775-150385573)x1 copy number loss not specified [RCV003986097] Chr1:149713775..150385573 [GRCh37]
Chr1:1q21.2-21.3		 pathogenic
GRCh37/hg19 1q21.1-23.1(chr1:146577511-157155587)x3 copy number gain not specified [RCV003987261] Chr1:146577511..157155587 [GRCh37]
Chr1:1q21.1-23.1		 pathogenic
Markers in Region
SHGC-57126  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371149,831,821 - 149,832,073UniSTSGRCh37
GRCh371149,804,873 - 149,805,125UniSTSGRCh37
Build 361148,071,497 - 148,071,749RGDNCBI36
Cytogenetic Map1q21UniSTS
HuRef1121,214,544 - 121,214,796UniSTS
HuRef1121,187,581 - 121,187,833UniSTS
RH66497  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371149,834,384 - 149,834,524UniSTSGRCh37
GRCh371149,802,422 - 149,802,562UniSTSGRCh37
Build 361148,069,046 - 148,069,186RGDNCBI36
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map1q21UniSTS
HuRef1121,217,105 - 121,217,245UniSTS
HuRef1121,185,132 - 121,185,272UniSTS
GeneMap99-GB4 RH Map1536.52UniSTS
D1S3163  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371149,803,390 - 149,803,665UniSTSGRCh37
GRCh371149,833,281 - 149,833,556UniSTSGRCh37
Build 361148,070,014 - 148,070,289RGDNCBI36
Cytogenetic Map1q21UniSTS
Cytogenetic Map1q21.2UniSTS
HuRef1121,216,002 - 121,216,277UniSTS
HuRef1121,186,100 - 121,186,375UniSTS
UniSTS:485772  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371149,832,347 - 149,832,719UniSTSGRCh37
GRCh371149,804,227 - 149,804,599UniSTSGRCh37
Build 361148,070,851 - 148,071,223RGDNCBI36
HuRef1121,186,937 - 121,187,309UniSTS
HuRef1121,215,068 - 121,215,440UniSTS
RH93503  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21UniSTS
GeneMap99-GB4 RH Map1551.93UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001034077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_168446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_168447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_168448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047424434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047424436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047424439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047424442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054337526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC239868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL591493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC108260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR542172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000377727   ⟹   ENSP00000366956
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl626,285,126 - 26,285,534 (-)Ensembl
RefSeq Acc Id: ENST00000579512   ⟹   ENSP00000462355
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1149,860,764 - 149,861,159 (-)Ensembl
RefSeq Acc Id: ENST00000612061   ⟹   ENSP00000482412
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1149,859,185 - 149,861,148 (-)Ensembl
RefSeq Acc Id: ENST00000615164   ⟹   ENSP00000484789
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl626,204,610 - 26,205,021 (+)Ensembl
RefSeq Acc Id: ENST00000621520   ⟹   ENSP00000481507
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1149,854,045 - 149,861,138 (-)Ensembl
RefSeq Acc Id: ENST00000634560   ⟹   ENSP00000489319
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl626,281,055 - 26,285,534 (-)Ensembl
RefSeq Acc Id: ENST00000634956   ⟹   ENSP00000489567
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl626,277,609 - 26,285,638 (-)Ensembl
RefSeq Acc Id: NM_001034077   ⟹   NP_001029249
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,860,764 - 149,861,159 (-)NCBI
GRCh371149,830,749 - 149,832,776 (-)NCBI
Build 361148,098,954 - 148,099,349 (-)NCBI Archive
HuRef1121,186,931 - 121,187,326 (+)RGD
CHM1_11151,228,890 - 151,229,285 (-)NCBI
T2T-CHM13v2.01148,984,910 - 148,985,305 (-)NCBI
Sequence:
RefSeq Acc Id: NR_168446
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,859,185 - 149,861,159 (-)NCBI
T2T-CHM13v2.01148,983,331 - 148,985,305 (-)NCBI
Sequence:
RefSeq Acc Id: NR_168447
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,854,095 - 149,861,159 (-)NCBI
T2T-CHM13v2.01148,978,230 - 148,985,305 (-)NCBI
Sequence:
RefSeq Acc Id: NR_168448
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,859,185 - 149,861,159 (-)NCBI
T2T-CHM13v2.01148,983,331 - 148,985,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024451708   ⟹   XP_024307476
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,844,488 - 149,861,159 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047424434   ⟹   XP_047280390
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,844,488 - 149,861,159 (-)NCBI
RefSeq Acc Id: XM_047424436   ⟹   XP_047280392
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,859,185 - 149,861,240 (-)NCBI
RefSeq Acc Id: XM_047424439   ⟹   XP_047280395
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,844,488 - 149,861,159 (-)NCBI
RefSeq Acc Id: XM_047424442   ⟹   XP_047280398
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,844,488 - 149,861,159 (-)NCBI
RefSeq Acc Id: XM_054337526   ⟹   XP_054193501
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01148,983,331 - 148,985,386 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001029249   ⟸   NM_001034077
- UniProtKB: Q6FGB8 (UniProtKB/Swiss-Prot),   Q6DRA9 (UniProtKB/Swiss-Prot),   P02305 (UniProtKB/Swiss-Prot),   P02304 (UniProtKB/Swiss-Prot),   A2VCL0 (UniProtKB/Swiss-Prot),   Q6NWP7 (UniProtKB/Swiss-Prot),   P62805 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024307476   ⟸   XM_024451708
- Peptide Label: isoform X1
- UniProtKB: Q6FGB8 (UniProtKB/Swiss-Prot),   Q6DRA9 (UniProtKB/Swiss-Prot),   P62805 (UniProtKB/Swiss-Prot),   P02305 (UniProtKB/Swiss-Prot),   P02304 (UniProtKB/Swiss-Prot),   A2VCL0 (UniProtKB/Swiss-Prot),   Q6NWP7 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000481507   ⟸   ENST00000621520
RefSeq Acc Id: ENSP00000482412   ⟸   ENST00000612061
RefSeq Acc Id: ENSP00000462355   ⟸   ENST00000579512
RefSeq Acc Id: XP_047280398   ⟸   XM_047424442
- Peptide Label: isoform X1
- UniProtKB: Q6FGB8 (UniProtKB/Swiss-Prot),   Q6DRA9 (UniProtKB/Swiss-Prot),   P62805 (UniProtKB/Swiss-Prot),   P02305 (UniProtKB/Swiss-Prot),   P02304 (UniProtKB/Swiss-Prot),   A2VCL0 (UniProtKB/Swiss-Prot),   Q6NWP7 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047280395   ⟸   XM_047424439
- Peptide Label: isoform X1
- UniProtKB: Q6FGB8 (UniProtKB/Swiss-Prot),   Q6DRA9 (UniProtKB/Swiss-Prot),   P62805 (UniProtKB/Swiss-Prot),   P02305 (UniProtKB/Swiss-Prot),   P02304 (UniProtKB/Swiss-Prot),   A2VCL0 (UniProtKB/Swiss-Prot),   Q6NWP7 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047280390   ⟸   XM_047424434
- Peptide Label: isoform X1
- UniProtKB: Q6FGB8 (UniProtKB/Swiss-Prot),   Q6DRA9 (UniProtKB/Swiss-Prot),   P62805 (UniProtKB/Swiss-Prot),   P02305 (UniProtKB/Swiss-Prot),   P02304 (UniProtKB/Swiss-Prot),   A2VCL0 (UniProtKB/Swiss-Prot),   Q6NWP7 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047280392   ⟸   XM_047424436
- Peptide Label: isoform X1
- UniProtKB: Q6FGB8 (UniProtKB/Swiss-Prot),   Q6DRA9 (UniProtKB/Swiss-Prot),   P62805 (UniProtKB/Swiss-Prot),   P02305 (UniProtKB/Swiss-Prot),   P02304 (UniProtKB/Swiss-Prot),   A2VCL0 (UniProtKB/Swiss-Prot),   Q6NWP7 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSP00000484789   ⟸   ENST00000615164
RefSeq Acc Id: ENSP00000489319   ⟸   ENST00000634560
RefSeq Acc Id: ENSP00000489567   ⟸   ENST00000634956
RefSeq Acc Id: ENSP00000366956   ⟸   ENST00000377727
RefSeq Acc Id: XP_054193501   ⟸   XM_054337526
- Peptide Label: isoform X1
- UniProtKB: Q6FGB8 (UniProtKB/Swiss-Prot),   Q6DRA9 (UniProtKB/Swiss-Prot),   P62805 (UniProtKB/Swiss-Prot),   P02305 (UniProtKB/Swiss-Prot),   P02304 (UniProtKB/Swiss-Prot),   A2VCL0 (UniProtKB/Swiss-Prot),   Q6NWP7 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
Protein Domains
TATA box binding protein associated factor (TAF)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62805-F1-model_v2 AlphaFold P62805 1-103 view protein structure

Promoters
RGD ID:6856918
Promoter ID:EPDNEW_H1624
Type:multiple initiation site
Name:HIST2H4B_1
Description:histone cluster 2 H4 family member b
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381149,861,159 - 149,861,219EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:29607 AgrOrtholog
COSMIC H4C15 COSMIC
Ensembl Genes ENSG00000158406 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000197061 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000197238 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000197837 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000270276 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000270882 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000273542 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000274618 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000275126 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000276180 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000276966 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000277157 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000278637 Ensembl, UniProtKB/Swiss-Prot
  ENSG00000278705 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000244537.6 UniProtKB/Swiss-Prot
  ENST00000355057.3 UniProtKB/Swiss-Prot
  ENST00000358064.3 UniProtKB/Swiss-Prot
  ENST00000377727.2 UniProtKB/Swiss-Prot
  ENST00000377745.5 UniProtKB/Swiss-Prot
  ENST00000377803.4 UniProtKB/Swiss-Prot
  ENST00000539745.2 UniProtKB/Swiss-Prot
  ENST00000578186.3 UniProtKB/Swiss-Prot
  ENST00000579512 ENTREZGENE
  ENST00000579512.3 UniProtKB/Swiss-Prot
  ENST00000611927.2 UniProtKB/Swiss-Prot
  ENST00000612061 ENTREZGENE
  ENST00000612061.1 UniProtKB/Swiss-Prot
  ENST00000613412.1 UniProtKB/Swiss-Prot
  ENST00000614247.2 UniProtKB/Swiss-Prot
  ENST00000614272.1 UniProtKB/Swiss-Prot
  ENST00000615164.3 UniProtKB/Swiss-Prot
  ENST00000615353.2 UniProtKB/Swiss-Prot
  ENST00000617569.2 UniProtKB/Swiss-Prot
  ENST00000618193.1 UniProtKB/Swiss-Prot
  ENST00000618305.2 UniProtKB/Swiss-Prot
  ENST00000621520.1 UniProtKB/Swiss-Prot
  ENST00000634560.1 UniProtKB/Swiss-Prot
  ENST00000634956.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000158406 GTEx
  ENSG00000197061 GTEx
  ENSG00000197238 GTEx
  ENSG00000197837 GTEx
  ENSG00000270276 GTEx
  ENSG00000270882 GTEx
  ENSG00000273542 GTEx
  ENSG00000274618 GTEx
  ENSG00000275126 GTEx
  ENSG00000276180 GTEx
  ENSG00000276966 GTEx
  ENSG00000277157 GTEx
  ENSG00000278637 GTEx
  ENSG00000278705 GTEx
HGNC ID HGNC:29607 ENTREZGENE
Human Proteome Map H4C15 Human Proteome Map
InterPro CENP-T/H4_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H4_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAF_TATA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:121504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:554313 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8359 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8361 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8362 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8363 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8364 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8365 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8366 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8367 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8368 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 554313 ENTREZGENE
PANTHER HISTONE H4 UniProtKB/Swiss-Prot
  HISTONE H4 UniProtKB/Swiss-Prot
  HISTONE H4 UniProtKB/TrEMBL
  HISTONE H4 UniProtKB/TrEMBL
Pfam CENP-T_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS HISTONEH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HISTONE_H4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2VCL0 ENTREZGENE
  B2R4R0 ENTREZGENE, UniProtKB/TrEMBL
  H4_HUMAN UniProtKB/Swiss-Prot
  P02304 ENTREZGENE
  P02305 ENTREZGENE
  P62805 ENTREZGENE
  Q6DRA9 ENTREZGENE
  Q6FGB8 ENTREZGENE
  Q6NWP7 ENTREZGENE
UniProt Secondary A2VCL0 UniProtKB/Swiss-Prot
  P02304 UniProtKB/Swiss-Prot
  P02305 UniProtKB/Swiss-Prot
  Q6DRA9 UniProtKB/Swiss-Prot
  Q6FGB8 UniProtKB/Swiss-Prot
  Q6NWP7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-30 H4C15  H4 clustered histone 15  HIST2H4B  histone cluster 2 H4 family member b  Symbol and/or name change 5135510 APPROVED
2016-08-23 HIST2H4B  histone cluster 2 H4 family member b  HIST2H4B  histone cluster 2, H4b  Symbol and/or name change 5135510 APPROVED