DCAF1 (DDB1 and CUL4 associated factor 1) - Rat Genome Database

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Gene: DCAF1 (DDB1 and CUL4 associated factor 1) Homo sapiens
Analyze
Symbol: DCAF1
Name: DDB1 and CUL4 associated factor 1
RGD ID: 1605417
HGNC Page HGNC:30911
Description: Enables histone kinase activity (H2A-T120 specific) and nuclear estrogen receptor binding activity. Involved in cell competition in a multicellular organism; negative regulation of transcription by RNA polymerase II; and post-translational protein modification. Located in fibrillar center and nucleoplasm. Part of Cul4-RING E3 ubiquitin ligase complex. Colocalizes with COP9 signalosome.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DDB1- and CUL4-associated factor 1; HIV-1 Vpr-binding protein; KIAA0800; MGC102804; RIP; serine/threonine-protein kinase VPRBP; Vpr-binding protein; vpr-interacting protein; VPRBP
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,395,867 - 51,505,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl351,395,867 - 51,500,015 (-)EnsemblGRCh38hg38GRCh38
GRCh37351,433,298 - 51,534,031 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,408,338 - 51,509,041 (-)NCBINCBI36hg18NCBI36
Celera351,407,652 - 51,511,665 (-)NCBI
Cytogenetic Map3p21.2NCBI
HuRef351,490,525 - 51,594,696 (-)NCBIHuRef
CHM1_1351,385,206 - 51,485,919 (-)NCBICHM1_1
T2T-CHM13v2.0351,426,284 - 51,530,457 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8195203   PMID:9872452   PMID:11223251   PMID:12111997   PMID:12477932   PMID:14702039   PMID:15342556   PMID:15385968   PMID:16888644   PMID:16949367   PMID:17079684   PMID:17314515  
PMID:17559673   PMID:17609381   PMID:17620334   PMID:17626091   PMID:17630831   PMID:17855541   PMID:18187620   PMID:18332868   PMID:18464893   PMID:18514189   PMID:18541215   PMID:18606781  
PMID:18775313   PMID:18829761   PMID:18850735   PMID:19029839   PMID:19264781   PMID:19275579   PMID:19275585   PMID:19275588   PMID:19287380   PMID:19295130   PMID:19380743   PMID:19458171  
PMID:19490893   PMID:19615732   PMID:19657269   PMID:19667756   PMID:19798433   PMID:19838296   PMID:19923175   PMID:20008788   PMID:20012529   PMID:20018238   PMID:20069611   PMID:20089662  
PMID:20178741   PMID:20347598   PMID:20360068   PMID:20380700   PMID:20562859   PMID:20644714   PMID:20824083   PMID:20870715   PMID:21145461   PMID:21226479   PMID:21318276   PMID:21489275  
PMID:21526938   PMID:21566118   PMID:21696578   PMID:21750658   PMID:21873635   PMID:21918813   PMID:21957298   PMID:21994772   PMID:22038470   PMID:22072767   PMID:22157821   PMID:22184063  
PMID:22190034   PMID:22190037   PMID:22292079   PMID:22362772   PMID:22386056   PMID:22422068   PMID:22438978   PMID:22570418   PMID:22658674   PMID:22776683   PMID:22939629   PMID:22963397  
PMID:23062609   PMID:23063525   PMID:23362280   PMID:23443559   PMID:23472066   PMID:23612978   PMID:23667531   PMID:23677995   PMID:23849790   PMID:24116224   PMID:24140421   PMID:24239288  
PMID:24336198   PMID:24360965   PMID:24366813   PMID:24402277   PMID:24412650   PMID:24528857   PMID:24558487   PMID:24703702   PMID:24706749   PMID:24719410   PMID:24744753   PMID:24778252  
PMID:24912773   PMID:24912982   PMID:24932481   PMID:25026211   PMID:25105968   PMID:25200749   PMID:25320300   PMID:25464830   PMID:25496524   PMID:25499532   PMID:25532805   PMID:25557551  
PMID:25618414   PMID:25659891   PMID:25665578   PMID:25720411   PMID:25807049   PMID:25921289   PMID:26032416   PMID:26170450   PMID:26186194   PMID:26186441   PMID:26281983   PMID:26344197  
PMID:26496610   PMID:26549023   PMID:26613412   PMID:26638075   PMID:26679995   PMID:26687479   PMID:26950368   PMID:26972000   PMID:27114546   PMID:27173435   PMID:27354282   PMID:27460548  
PMID:27571178   PMID:27626385   PMID:27721409   PMID:28068668   PMID:28077445   PMID:28202763   PMID:28242625   PMID:28242748   PMID:28289176   PMID:28380382   PMID:28416635   PMID:28424288  
PMID:28514442   PMID:28581483   PMID:28675297   PMID:29079575   PMID:29180619   PMID:29229926   PMID:29327233   PMID:29467282   PMID:29507117   PMID:29507755   PMID:29724823   PMID:29883611  
PMID:30100344   PMID:30118682   PMID:30166453   PMID:30352932   PMID:30590706   PMID:30619335   PMID:31003777   PMID:31091453   PMID:31291647   PMID:31452512   PMID:31511615   PMID:31753913  
PMID:31973889   PMID:31980649   PMID:32171724   PMID:32640226   PMID:32838362   PMID:33005030   PMID:33058421   PMID:33355139   PMID:33504946   PMID:33648539   PMID:33957083   PMID:33961781  
PMID:34011540   PMID:34091597   PMID:34259627   PMID:34299191   PMID:34312968   PMID:34373451   PMID:34595758   PMID:34711951   PMID:35007762   PMID:35271311   PMID:35348747  


Genomics

Comparative Map Data
DCAF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,395,867 - 51,505,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl351,395,867 - 51,500,015 (-)EnsemblGRCh38hg38GRCh38
GRCh37351,433,298 - 51,534,031 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,408,338 - 51,509,041 (-)NCBINCBI36hg18NCBI36
Celera351,407,652 - 51,511,665 (-)NCBI
Cytogenetic Map3p21.2NCBI
HuRef351,490,525 - 51,594,696 (-)NCBIHuRef
CHM1_1351,385,206 - 51,485,919 (-)NCBICHM1_1
T2T-CHM13v2.0351,426,284 - 51,530,457 (-)NCBI
Dcaf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,691,354 - 106,758,191 (+)NCBIGRCm39mm39
GRCm39 Ensembl9106,699,073 - 106,758,191 (+)Ensembl
GRCm389106,814,169 - 106,880,992 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,821,874 - 106,880,992 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,724,307 - 106,783,323 (+)NCBIGRCm37mm9NCBIm37
MGSCv369106,680,077 - 106,738,533 (+)NCBImm8
Celera9106,446,540 - 106,505,051 (+)NCBICelera
Cytogenetic Map9F1NCBI
Dcaf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28107,466,229 - 107,540,633 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl8107,474,312 - 107,540,627 (+)Ensembl
Rnor_6.08115,538,365 - 115,615,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,546,712 - 115,615,282 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,898,496 - 114,974,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,034,908 - 112,102,320 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18112,061,887 - 112,120,790 (+)NCBI
Celera8106,786,375 - 106,852,580 (+)NCBICelera
Cytogenetic Map8q32NCBI
Dcaf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,085,386 - 3,154,671 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,085,386 - 3,153,952 (-)NCBIChiLan1.0ChiLan1.0
DCAF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1352,560,427 - 52,668,919 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl352,560,427 - 52,663,807 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0351,326,589 - 51,430,217 (-)NCBIMhudiblu_PPA_v0panPan3
DCAF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12038,109,974 - 38,187,621 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2038,125,078 - 38,187,107 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2038,089,540 - 38,167,146 (+)NCBI
ROS_Cfam_1.02038,458,824 - 38,536,454 (+)NCBI
ROS_Cfam_1.0 Ensembl2038,464,033 - 38,536,453 (+)Ensembl
UMICH_Zoey_3.12037,822,249 - 37,899,846 (+)NCBI
UNSW_CanFamBas_1.02038,226,332 - 38,304,159 (+)NCBI
UU_Cfam_GSD_1.02038,516,174 - 38,593,797 (+)NCBI
Dcaf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,025,750 - 66,101,560 (-)NCBI
SpeTri2.0NW_0049365292,786,252 - 2,856,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1333,670,977 - 33,750,772 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11333,670,976 - 33,750,872 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21336,900,767 - 36,968,157 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12212,736,784 - 12,843,762 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2212,739,665 - 12,823,363 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041154,127,859 - 154,231,832 (+)NCBIVero_WHO_p1.0
Dcaf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,176,828 - 5,240,680 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247305,176,828 - 5,245,548 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D3S3947  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37351,435,073 - 51,435,251UniSTSGRCh37
Build 36351,410,113 - 51,410,291RGDNCBI36
Celera351,409,427 - 51,409,605RGD
Cytogenetic Map3p21.2UniSTS
HuRef351,492,300 - 51,492,478UniSTS
GeneMap99-GB4 RH Map3161.69UniSTS
Whitehead-RH Map3209.6UniSTS
Whitehead-YAC Contig Map3 UniSTS
NCBI RH Map3487.8UniSTS
D3S2871E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37351,435,123 - 51,435,228UniSTSGRCh37
Build 36351,410,163 - 51,410,268RGDNCBI36
Celera351,409,477 - 51,409,582RGD
Cytogenetic Map3p21.2UniSTS
HuRef351,492,350 - 51,492,455UniSTS
TNG Radiation Hybrid Map331913.0UniSTS
Stanford-G3 RH Map32303.0UniSTS
GeneMap99-GB4 RH Map3160.91UniSTS
NCBI RH Map3488.5UniSTS
GeneMap99-G3 RH Map32201.0UniSTS
RH93354  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37351,433,338 - 51,433,531UniSTSGRCh37
Build 36351,408,378 - 51,408,571RGDNCBI36
Celera351,407,692 - 51,407,885RGD
Cytogenetic Map3p21.2UniSTS
HuRef351,490,565 - 51,490,758UniSTS
GeneMap99-GB4 RH Map3161.1UniSTS
RH41778  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37351,435,107 - 51,435,222UniSTSGRCh37
Build 36351,410,147 - 51,410,262RGDNCBI36
Celera351,409,461 - 51,409,576RGD
Cytogenetic Map3p21.2UniSTS
HuRef351,492,334 - 51,492,449UniSTS
GeneMap99-GB4 RH Map3160.02UniSTS
SHGC-57673  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37351,435,469 - 51,435,571UniSTSGRCh37
Build 36351,410,509 - 51,410,611RGDNCBI36
Celera351,409,823 - 51,409,925RGD
Cytogenetic Map3p21.2UniSTS
HuRef351,492,696 - 51,492,798UniSTS
TNG Radiation Hybrid Map331921.0UniSTS
HUMAGCGB_9597  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37351,434,574 - 51,435,443UniSTSGRCh37
Build 36351,409,614 - 51,410,483RGDNCBI36
Celera351,408,928 - 51,409,797RGD
HuRef351,491,801 - 51,492,670UniSTS
D3S4443  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37351,433,938 - 51,434,041UniSTSGRCh37
Build 36351,408,978 - 51,409,081RGDNCBI36
Celera351,408,292 - 51,408,395RGD
Cytogenetic Map3p21.2UniSTS
HuRef351,491,165 - 51,491,268UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1101
Count of miRNA genes:746
Interacting mature miRNAs:834
Transcripts:ENST00000335891, ENST00000423656, ENST00000504652
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2035 1413 1276 252 1173 109 4274 1606 1536 233 1394 1580 158 1 1144 2723 6 2
Low 404 1564 450 372 764 356 83 591 2198 186 66 33 17 60 65
Below cutoff 14 14

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001171904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_014703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_170668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005276753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005276755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011534273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011534275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001740385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001740387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB018343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC092037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC233756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF061935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF086402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL080145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP222559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR986856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000335891   ⟹   ENSP00000338857
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl351,397,842 - 51,483,838 (-)Ensembl
RefSeq Acc Id: ENST00000423656   ⟹   ENSP00000393183
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl351,395,867 - 51,499,994 (-)Ensembl
RefSeq Acc Id: ENST00000504652   ⟹   ENSP00000421724
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl351,395,867 - 51,500,002 (-)Ensembl
RefSeq Acc Id: ENST00000684031   ⟹   ENSP00000506880
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl351,397,842 - 51,500,015 (-)Ensembl
RefSeq Acc Id: NM_001171904   ⟹   NP_001165375
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
GRCh37351,433,298 - 51,534,018 (-)ENTREZGENE
HuRef351,490,525 - 51,594,696 (-)ENTREZGENE
CHM1_1351,385,206 - 51,485,919 (-)NCBI
T2T-CHM13v2.0351,426,284 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001349168   ⟹   NP_001336097
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001349169   ⟹   NP_001336098
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001349170   ⟹   NP_001336099
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001349171   ⟹   NP_001336100
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387578   ⟹   NP_001374507
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387579   ⟹   NP_001374508
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387580   ⟹   NP_001374509
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387581   ⟹   NP_001374510
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,426,284 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387582   ⟹   NP_001374511
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387583   ⟹   NP_001374512
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,428,259 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NM_014703   ⟹   NP_055518
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
GRCh37351,433,298 - 51,534,018 (-)ENTREZGENE
Build 36351,408,338 - 51,509,041 (-)NCBI Archive
HuRef351,490,525 - 51,594,696 (-)ENTREZGENE
CHM1_1351,385,206 - 51,485,919 (-)NCBI
T2T-CHM13v2.0351,426,284 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NR_146065
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,426,284 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: NR_170668
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
T2T-CHM13v2.0351,426,284 - 51,530,457 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005276753   ⟹   XP_005276810
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,484,220 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005276755   ⟹   XP_005276812
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,505,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011534273   ⟹   XP_011532575
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,505,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011534275   ⟹   XP_011532577
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,505,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017007547   ⟹   XP_016863036
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,505,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017007549   ⟹   XP_016863038
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047449269   ⟹   XP_047305225
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449270   ⟹   XP_047305226
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449271   ⟹   XP_047305227
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,499,331 (-)NCBI
RefSeq Acc Id: XM_047449272   ⟹   XP_047305228
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,505,639 (-)NCBI
RefSeq Acc Id: XM_047449273   ⟹   XP_047305229
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,505,639 (-)NCBI
RefSeq Acc Id: XM_047449274   ⟹   XP_047305230
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449275   ⟹   XP_047305231
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449276   ⟹   XP_047305232
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449277   ⟹   XP_047305233
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449278   ⟹   XP_047305234
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449279   ⟹   XP_047305235
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449280   ⟹   XP_047305236
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449281   ⟹   XP_047305237
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449282   ⟹   XP_047305238
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XM_047449283   ⟹   XP_047305239
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,397,842 - 51,426,008 (-)NCBI
RefSeq Acc Id: XR_001740385
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
Sequence:
RefSeq Acc Id: XR_007095772
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XR_007095773
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XR_007095774
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XR_007095775
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XR_007095776
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XR_007095777
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
RefSeq Acc Id: XR_007095778
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,395,867 - 51,500,015 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001165375 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336097 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336098 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336099 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336100 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374507 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374508 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374509 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374510 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374511 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374512 (Get FASTA)   NCBI Sequence Viewer  
  NP_055518 (Get FASTA)   NCBI Sequence Viewer  
  XP_005276810 (Get FASTA)   NCBI Sequence Viewer  
  XP_005276812 (Get FASTA)   NCBI Sequence Viewer  
  XP_011532575 (Get FASTA)   NCBI Sequence Viewer  
  XP_011532577 (Get FASTA)   NCBI Sequence Viewer  
  XP_016863036 (Get FASTA)   NCBI Sequence Viewer  
  XP_016863038 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305225 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305226 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305227 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305228 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305229 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305230 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305231 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305232 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305233 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305234 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305235 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305236 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305237 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305238 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305239 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG27134 (Get FASTA)   NCBI Sequence Viewer  
  AAH22792 (Get FASTA)   NCBI Sequence Viewer  
  AAI10372 (Get FASTA)   NCBI Sequence Viewer  
  BAA34520 (Get FASTA)   NCBI Sequence Viewer  
  BAG51173 (Get FASTA)   NCBI Sequence Viewer  
  CAB45738 (Get FASTA)   NCBI Sequence Viewer  
  EAW65140 (Get FASTA)   NCBI Sequence Viewer  
  EAW65141 (Get FASTA)   NCBI Sequence Viewer  
  EAW65142 (Get FASTA)   NCBI Sequence Viewer  
  EAW65143 (Get FASTA)   NCBI Sequence Viewer  
  Q9Y4B6 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001165375   ⟸   NM_001171904
- Peptide Label: isoform 2
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_055518   ⟸   NM_014703
- Peptide Label: isoform 1
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005276812   ⟸   XM_005276755
- Peptide Label: isoform X1
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005276810   ⟸   XM_005276753
- Peptide Label: isoform X1
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011532577   ⟸   XM_011534275
- Peptide Label: isoform X1
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011532575   ⟸   XM_011534273
- Peptide Label: isoform X1
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016863038   ⟸   XM_017007549
- Peptide Label: isoform X1
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016863036   ⟸   XM_017007547
- Peptide Label: isoform X1
- UniProtKB: Q9Y4B6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001336100   ⟸   NM_001349171
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: NP_001336099   ⟸   NM_001349170
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: NP_001336097   ⟸   NM_001349168
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: NP_001336098   ⟸   NM_001349169
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: ENSP00000393183   ⟸   ENST00000423656
RefSeq Acc Id: ENSP00000421724   ⟸   ENST00000504652
RefSeq Acc Id: ENSP00000338857   ⟸   ENST00000335891
RefSeq Acc Id: NP_001374510   ⟸   NM_001387581
- Peptide Label: isoform 1
RefSeq Acc Id: NP_001374511   ⟸   NM_001387582
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001374509   ⟸   NM_001387580
- Peptide Label: isoform 1
RefSeq Acc Id: NP_001374508   ⟸   NM_001387579
- Peptide Label: isoform 1
RefSeq Acc Id: NP_001374512   ⟸   NM_001387583
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001374507   ⟸   NM_001387578
- Peptide Label: isoform 1
RefSeq Acc Id: ENSP00000506880   ⟸   ENST00000684031
RefSeq Acc Id: XP_047305231   ⟸   XM_047449275
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047305225   ⟸   XM_047449269
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047305234   ⟸   XM_047449278
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047305226   ⟸   XM_047449270
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047305230   ⟸   XM_047449274
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047305238   ⟸   XM_047449282
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047305233   ⟸   XM_047449277
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047305232   ⟸   XM_047449276
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047305227   ⟸   XM_047449271
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047305229   ⟸   XM_047449273
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047305228   ⟸   XM_047449272
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047305235   ⟸   XM_047449279
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047305236   ⟸   XM_047449280
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047305237   ⟸   XM_047449281
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047305239   ⟸   XM_047449283
- Peptide Label: isoform X4
Protein Domains
Chromo   LisH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y4B6-F1-model_v2 AlphaFold Q9Y4B6 1-1507 view protein structure

Promoters
RGD ID:6801935
Promoter ID:HG_KWN:45168
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:NB4
Transcripts:UC003DBF.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36351,432,481 - 51,432,981 (-)MPROMDB
RGD ID:6864560
Promoter ID:EPDNEW_H5445
Type:initiation region
Name:VPRBP_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5446  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,499,984 - 51,500,044EPDNEW
RGD ID:6864562
Promoter ID:EPDNEW_H5446
Type:initiation region
Name:VPRBP_2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5445  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38351,505,611 - 51,505,671EPDNEW
RGD ID:6801216
Promoter ID:HG_KWN:45170
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001171904,   NM_014703,   UC003DBG.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36351,508,591 - 51,509,427 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p21.31-14.3(chr3:49461000-55314500)x1 copy number loss See cases [RCV000051511] Chr3:49461000..55314500 [GRCh38]
Chr3:49498433..55348528 [GRCh37]
Chr3:49473437..55323568 [NCBI36]
Chr3:3p21.31-14.3
pathogenic
NM_001171904.1(VPRBP):c.1870G>A (p.Asp624Asn) single nucleotide variant Malignant melanoma [RCV000066132] Chr3:51422406 [GRCh38]
Chr3:51459857 [GRCh37]
Chr3:51434897 [NCBI36]
Chr3:3p21.2
not provided
NM_001171904.1(VPRBP):c.923C>T (p.Pro308Leu) single nucleotide variant Malignant melanoma [RCV000066133] Chr3:51441485 [GRCh38]
Chr3:51475501 [GRCh37]
Chr3:51450541 [NCBI36]
Chr3:3p21.2
not provided
GRCh38/hg38 3p21.2-14.3(chr3:51394434-55064449)x1 copy number loss See cases [RCV000143631] Chr3:51394434..55064449 [GRCh38]
Chr3:51431865..55098476 [GRCh37]
Chr3:51406905..55073516 [NCBI36]
Chr3:3p21.2-14.3
likely pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p21.31-21.1(chr3:45153770-53878616) copy number gain not provided [RCV000767704] Chr3:45153770..53878616 [GRCh37]
Chr3:3p21.31-21.1
pathogenic
GRCh37/hg19 3p21.2-21.1(chr3:51247306-53069942)x3 copy number gain not provided [RCV001005434] Chr3:51247306..53069942 [GRCh37]
Chr3:3p21.2-21.1
uncertain significance
GRCh37/hg19 3p21.2(chr3:51159973-51440650)x1 copy number loss not provided [RCV001259684] Chr3:51159973..51440650 [GRCh37]
Chr3:3p21.2
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30911 AgrOrtholog
COSMIC DCAF1 COSMIC
Ensembl Genes ENSG00000145041 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000338857.5 UniProtKB/Swiss-Prot
  ENSP00000393183 ENTREZGENE
  ENSP00000393183.2 UniProtKB/Swiss-Prot
  ENSP00000421724 ENTREZGENE
  ENSP00000421724.2 UniProtKB/Swiss-Prot
  ENSP00000506880 ENTREZGENE
  ENSP00000506880.1 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000335891.5 UniProtKB/Swiss-Prot
  ENST00000423656 ENTREZGENE
  ENST00000423656.5 UniProtKB/Swiss-Prot
  ENST00000504652 ENTREZGENE
  ENST00000504652.5 UniProtKB/Swiss-Prot
  ENST00000684031 ENTREZGENE
  ENST00000684031.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot
  2.130.10.10 UniProtKB/Swiss-Prot
GTEx ENSG00000145041 GTEx
HGNC ID HGNC:30911 ENTREZGENE
Human Proteome Map DCAF1 Human Proteome Map
InterPro ARM-like UniProtKB/Swiss-Prot
  ARM-type_fold UniProtKB/Swiss-Prot
  LisH UniProtKB/Swiss-Prot
  VPRBP/DCAF1 UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report hsa:9730 UniProtKB/Swiss-Prot
NCBI Gene 9730 ENTREZGENE
OMIM 617259 OMIM
PANTHER PTHR13129 UniProtKB/Swiss-Prot
PharmGKB PA142670621 PharmGKB
PROSITE LISH UniProtKB/Swiss-Prot
SMART LisH UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot
  SSF50978 UniProtKB/Swiss-Prot
UniProt DCAF1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q2YD74 UniProtKB/Swiss-Prot
  Q8TBD9 UniProtKB/Swiss-Prot
  Q9HCA1 UniProtKB/Swiss-Prot
  Q9UG37 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-14 DCAF1  DDB1 and CUL4 associated factor 1  VPRBP  Vpr (HIV-1) binding protein  Symbol and/or name change 5135510 APPROVED