IST1 (IST1 factor associated with ESCRT-III) - Rat Genome Database

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Gene: IST1 (IST1 factor associated with ESCRT-III) Homo sapiens
Analyze
Symbol: IST1
Name: IST1 factor associated with ESCRT-III
RGD ID: 1605407
HGNC Page HGNC
Description: Enables MIT domain binding activity and identical protein binding activity. Involved in several processes, including positive regulation of proteolysis; viral capsid secondary envelopment; and viral release from host cell. Located in several cellular components, including Flemming body; endoplasmic reticulum-Golgi intermediate compartment; and extracellular exosome. Colocalizes with chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHMP8; hIST1; increased sodium tolerance 1 homolog; increased sodium tolerance-1; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; IST1, ESCRT-III associated factor; KIAA0174; MGC117220; OLC1; overexpressed in lung cancer 1; putative MAPK-activating protein PM28
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC728533  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1671,845,996 - 71,931,199 (+)EnsemblGRCh38hg38GRCh38
GRCh381671,894,408 - 71,931,199 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371671,928,311 - 71,965,102 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361670,486,947 - 70,520,407 (+)NCBINCBI36hg18NCBI36
Celera1656,243,371 - 56,276,822 (+)NCBI
Cytogenetic Map16q22.2NCBI
HuRef1657,696,177 - 57,731,724 (+)NCBIHuRef
CHM1_11673,341,627 - 73,377,874 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8724849   PMID:10942595   PMID:12477932   PMID:12761501   PMID:14702039   PMID:15489334   PMID:15592455   PMID:16189514   PMID:16344560   PMID:16713569   PMID:17207965   PMID:18951430  
PMID:19001597   PMID:19001599   PMID:19056867   PMID:19129479   PMID:19129480   PMID:19199708   PMID:19477918   PMID:19525971   PMID:19738201   PMID:20458337   PMID:20588296   PMID:20719964  
PMID:20849418   PMID:21439932   PMID:21557262   PMID:21616915   PMID:21674799   PMID:21706489   PMID:21873635   PMID:22020285   PMID:22340600   PMID:22623428   PMID:22863883   PMID:22939629  
PMID:23015756   PMID:23045692   PMID:23376485   PMID:23533145   PMID:23609236   PMID:23649269   PMID:23897888   PMID:24403489   PMID:24608342   PMID:24880589   PMID:24953135   PMID:25416956  
PMID:25468996   PMID:25657007   PMID:26011858   PMID:26040712   PMID:26186194   PMID:26344197   PMID:26472760   PMID:26496610   PMID:26549023   PMID:27342126   PMID:28038462   PMID:28242692  
PMID:28514442   PMID:28532543   PMID:28718761   PMID:29128334   PMID:29509190   PMID:29987050   PMID:30110633   PMID:30471916   PMID:31091453   PMID:31227594   PMID:31527615   PMID:32149426  
PMID:32251413   PMID:32296183   PMID:32513696   PMID:32780723   PMID:32814053   PMID:32994395   PMID:33001583  


Genomics

Comparative Map Data
IST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1671,845,996 - 71,931,199 (+)EnsemblGRCh38hg38GRCh38
GRCh381671,894,408 - 71,931,199 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371671,928,311 - 71,965,102 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361670,486,947 - 70,520,407 (+)NCBINCBI36hg18NCBI36
Celera1656,243,371 - 56,276,822 (+)NCBI
Cytogenetic Map16q22.2NCBI
HuRef1657,696,177 - 57,731,724 (+)NCBIHuRef
CHM1_11673,341,627 - 73,377,874 (+)NCBICHM1_1
Ist1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398110,397,953 - 110,419,929 (-)NCBIGRCm39mm39
GRCm39 Ensembl8110,397,957 - 110,419,892 (-)Ensembl
GRCm388109,671,321 - 109,693,297 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8109,671,325 - 109,693,260 (-)EnsemblGRCm38mm10GRCm38
MGSCv378112,195,221 - 112,217,194 (-)NCBIGRCm37mm9NCBIm37
MGSCv368112,560,458 - 112,582,393 (-)NCBImm8
Celera8113,896,960 - 113,918,958 (-)NCBICelera
Cytogenetic Map8D3NCBI
Ist1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21937,648,840 - 37,671,019 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1937,648,095 - 37,670,956 (-)Ensembl
Rnor_6.01941,968,692 - 41,990,843 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,968,705 - 41,990,843 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01952,793,716 - 52,815,862 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41939,554,205 - 39,576,343 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11939,559,093 - 39,581,181 (-)NCBI
Celera1937,052,746 - 37,074,884 (-)NCBICelera
Cytogenetic Map19q12NCBI
Ist1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554844,589,311 - 4,630,203 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554844,589,311 - 4,630,464 (+)NCBIChiLan1.0ChiLan1.0
IST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11671,733,868 - 71,765,969 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1671,733,302 - 71,765,969 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01653,082,530 - 53,115,965 (-)NCBIMhudiblu_PPA_v0panPan3
IST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,660,033 - 77,693,831 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,660,081 - 77,692,396 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,621,109 - 77,655,606 (+)NCBI
ROS_Cfam_1.0578,099,321 - 78,133,852 (+)NCBI
UMICH_Zoey_3.1577,919,418 - 77,953,932 (+)NCBI
UNSW_CanFamBas_1.0577,742,127 - 77,776,623 (+)NCBI
UU_Cfam_GSD_1.0578,241,426 - 78,275,957 (+)NCBI
LOC101977053
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934937,680,804 - 37,699,103 (+)NCBI
SpeTri2.0NW_00493647521,890,011 - 21,908,256 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,836,749 - 14,911,313 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1614,868,859 - 14,910,679 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2614,465,663 - 14,489,764 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1555,030,916 - 55,063,824 (+)NCBI
ChlSab1.1 Ensembl555,050,795 - 55,064,549 (+)Ensembl
Vero_WHO_p1.0NW_02366604717,832,602 - 17,864,267 (+)NCBI

Position Markers
NIB727  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371671,962,662 - 71,962,851UniSTSGRCh37
GRCh371256,057,704 - 56,057,892UniSTSGRCh37
Build 361254,343,971 - 54,344,159RGDNCBI36
Celera1656,276,578 - 56,276,767UniSTS
Celera1255,710,172 - 55,710,360RGD
Cytogenetic Map16q22.2UniSTS
HuRef1253,096,525 - 53,096,713UniSTS
HuRef1657,729,844 - 57,730,033UniSTS
Stanford-G3 RH Map162761.0UniSTS
NCBI RH Map16557.9UniSTS
GeneMap99-G3 RH Map163205.0UniSTS
RH91143  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371938,284,515 - 38,284,636UniSTSGRCh37
GRCh371671,962,723 - 71,962,844UniSTSGRCh37
Build 361670,520,224 - 70,520,345RGDNCBI36
Celera1935,084,862 - 35,084,983UniSTS
Celera1656,276,639 - 56,276,760RGD
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map16q22.2UniSTS
HuRef1934,734,283 - 34,734,404UniSTS
HuRef1657,729,905 - 57,730,026UniSTS
D19S846  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371938,284,519 - 38,284,624UniSTSGRCh37
GRCh371671,962,727 - 71,962,832UniSTSGRCh37
Build 361670,520,228 - 70,520,333RGDNCBI36
Celera1935,084,866 - 35,084,971UniSTS
Celera1656,276,643 - 56,276,748RGD
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map16q22.2UniSTS
HuRef1934,734,287 - 34,734,392UniSTS
HuRef1657,729,909 - 57,730,014UniSTS
D16S2946  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371671,962,657 - 71,962,906UniSTSGRCh37
Build 361670,520,158 - 70,520,407RGDNCBI36
Celera1656,276,573 - 56,276,822RGD
Cytogenetic Map16q22.2UniSTS
HuRef1657,729,839 - 57,730,088UniSTS
Whitehead-YAC Contig Map16 UniSTS
SHGC-60641  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371671,962,703 - 71,962,819UniSTSGRCh37
Build 361670,520,204 - 70,520,320RGDNCBI36
Celera1656,276,619 - 56,276,735RGD
Cytogenetic Map16q22.2UniSTS
HuRef1657,729,885 - 57,730,001UniSTS
GeneMap99-GB4 RH Map16434.6UniSTS
Whitehead-RH Map16312.9UniSTS
NCBI RH Map16508.6UniSTS
RH25390  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q22.2UniSTS
GDB:451592  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q22.2UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5892
Count of miRNA genes:1106
Interacting mature miRNAs:1369
Transcripts:ENST00000329908, ENST00000378798, ENST00000378799, ENST00000424485, ENST00000439924, ENST00000456820, ENST00000534994, ENST00000535424, ENST00000536027, ENST00000537571, ENST00000537613, ENST00000538104, ENST00000538565, ENST00000538709, ENST00000538850, ENST00000539186, ENST00000540296, ENST00000541180, ENST00000541571, ENST00000541918, ENST00000544564, ENST00000545388, ENST00000545518, ENST00000566536, ENST00000606369
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2439 2889 1716 614 1926 455 4357 2125 3674 419 1460 1613 175 1 1204 2788 6 2
Low 102 10 10 25 10 72 60
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_014761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB097052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC009127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK057902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK295066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL355695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC103745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX364250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ834562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ834564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ834566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D79996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA332434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA698420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000329908   ⟹   ENSP00000330408
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,543 - 71,929,010 (+)Ensembl
RefSeq Acc Id: ENST00000378798   ⟹   ENSP00000368075
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,553 - 71,929,008 (+)Ensembl
RefSeq Acc Id: ENST00000378799   ⟹   ENSP00000368076
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,531 - 71,931,199 (+)Ensembl
RefSeq Acc Id: ENST00000424485   ⟹   ENSP00000398505
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,508 - 71,920,817 (+)Ensembl
RefSeq Acc Id: ENST00000439924   ⟹   ENSP00000410081
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,915,626 - 71,929,002 (+)Ensembl
RefSeq Acc Id: ENST00000456820   ⟹   ENSP00000414942
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,916,560 - 71,928,974 (+)Ensembl
RefSeq Acc Id: ENST00000534994   ⟹   ENSP00000454541
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,553 - 71,922,540 (+)Ensembl
RefSeq Acc Id: ENST00000535424   ⟹   ENSP00000438399
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,894,719 - 71,930,639 (+)Ensembl
RefSeq Acc Id: ENST00000536027   ⟹   ENSP00000463833
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,922,627 - 71,928,049 (+)Ensembl
RefSeq Acc Id: ENST00000537571
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,920,760 - 71,923,509 (+)Ensembl
RefSeq Acc Id: ENST00000537613   ⟹   ENSP00000457646
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,494 - 71,922,680 (+)Ensembl
RefSeq Acc Id: ENST00000538104   ⟹   ENSP00000455590
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,894,405 - 71,916,493 (+)Ensembl
RefSeq Acc Id: ENST00000538565
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,531 - 71,928,339 (+)Ensembl
RefSeq Acc Id: ENST00000538709
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,921,424 - 71,922,934 (+)Ensembl
RefSeq Acc Id: ENST00000538850   ⟹   ENSP00000463711
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,548 - 71,928,152 (+)Ensembl
RefSeq Acc Id: ENST00000539186   ⟹   ENSP00000455757
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,589 - 71,921,400 (+)Ensembl
RefSeq Acc Id: ENST00000540296   ⟹   ENSP00000455409
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,885,233 - 71,916,552 (+)Ensembl
RefSeq Acc Id: ENST00000541180
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,924,408 - 71,927,838 (+)Ensembl
RefSeq Acc Id: ENST00000541571   ⟹   ENSP00000455860
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,893,934 - 71,927,973 (+)Ensembl
RefSeq Acc Id: ENST00000541918   ⟹   ENSP00000455805
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,551 - 71,922,681 (+)Ensembl
RefSeq Acc Id: ENST00000544564   ⟹   ENSP00000457844
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,890,569 - 71,927,890 (+)Ensembl
RefSeq Acc Id: ENST00000545388
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,921,104 - 71,922,753 (+)Ensembl
RefSeq Acc Id: ENST00000545518
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,916,525 - 71,921,762 (+)Ensembl
RefSeq Acc Id: ENST00000566536
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,510 - 71,920,898 (+)Ensembl
RefSeq Acc Id: ENST00000568581   ⟹   ENSP00000456200
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,845,996 - 71,917,094 (+)Ensembl
RefSeq Acc Id: ENST00000606369   ⟹   ENSP00000475853
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,895,493 - 71,930,639 (+)Ensembl
RefSeq Acc Id: ENST00000626438   ⟹   ENSP00000486751
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1671,915,641 - 71,922,511 (+)Ensembl
RefSeq Acc Id: NM_001270975   ⟹   NP_001257904
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,895,531 - 71,931,199 (+)NCBI
GRCh371671,928,311 - 71,964,542 (+)NCBI
HuRef1657,696,177 - 57,731,724 (+)NCBI
CHM1_11673,342,712 - 73,377,874 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270976   ⟹   NP_001257905
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,894,408 - 71,930,639 (+)NCBI
GRCh371671,928,311 - 71,964,542 (+)NCBI
HuRef1657,696,177 - 57,731,724 (+)NCBI
CHM1_11673,341,627 - 73,377,874 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270977   ⟹   NP_001257906
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,895,531 - 71,931,199 (+)NCBI
GRCh371671,928,311 - 71,964,542 (+)NCBI
HuRef1657,696,177 - 57,731,724 (+)NCBI
CHM1_11673,342,712 - 73,377,874 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270978   ⟹   NP_001257907
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,895,531 - 71,931,199 (+)NCBI
GRCh371671,928,311 - 71,964,542 (+)NCBI
HuRef1657,696,177 - 57,731,724 (+)NCBI
CHM1_11673,342,712 - 73,377,874 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270979   ⟹   NP_001257908
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,895,493 - 71,930,639 (+)NCBI
GRCh371671,928,311 - 71,964,542 (+)NCBI
HuRef1657,696,177 - 57,731,724 (+)NCBI
CHM1_11673,342,712 - 73,377,874 (+)NCBI
Sequence:
RefSeq Acc Id: NM_014761   ⟹   NP_055576
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,895,531 - 71,931,199 (+)NCBI
GRCh371671,928,311 - 71,964,542 (+)NCBI
Build 361670,486,947 - 70,520,407 (+)NCBI Archive
HuRef1657,696,177 - 57,731,724 (+)NCBI
CHM1_11673,342,712 - 73,377,874 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001257904 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257905 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257906 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257907 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257908 (Get FASTA)   NCBI Sequence Viewer  
  NP_055576 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH00116 (Get FASTA)   NCBI Sequence Viewer  
  AAH00430 (Get FASTA)   NCBI Sequence Viewer  
  AAH04359 (Get FASTA)   NCBI Sequence Viewer  
  AAI03746 (Get FASTA)   NCBI Sequence Viewer  
  BAA11491 (Get FASTA)   NCBI Sequence Viewer  
  BAC77405 (Get FASTA)   NCBI Sequence Viewer  
  BAF84077 (Get FASTA)   NCBI Sequence Viewer  
  BAF85711 (Get FASTA)   NCBI Sequence Viewer  
  BAF85729 (Get FASTA)   NCBI Sequence Viewer  
  BAG58114 (Get FASTA)   NCBI Sequence Viewer  
  BAG59603 (Get FASTA)   NCBI Sequence Viewer  
  BAG59792 (Get FASTA)   NCBI Sequence Viewer  
  BAG63341 (Get FASTA)   NCBI Sequence Viewer  
  CAH05496 (Get FASTA)   NCBI Sequence Viewer  
  CAH05497 (Get FASTA)   NCBI Sequence Viewer  
  CAH05498 (Get FASTA)   NCBI Sequence Viewer  
  EAW59205 (Get FASTA)   NCBI Sequence Viewer  
  EAW59206 (Get FASTA)   NCBI Sequence Viewer  
  EAW59207 (Get FASTA)   NCBI Sequence Viewer  
  EAW59208 (Get FASTA)   NCBI Sequence Viewer  
  EAW59209 (Get FASTA)   NCBI Sequence Viewer  
  P53990 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_055576   ⟸   NM_014761
- Peptide Label: isoform b
- UniProtKB: P53990 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257905   ⟸   NM_001270976
- Peptide Label: isoform c
- UniProtKB: P53990 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257904   ⟸   NM_001270975
- Peptide Label: isoform a
- UniProtKB: P53990 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257906   ⟸   NM_001270977
- Peptide Label: isoform d
- UniProtKB: P53990 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257907   ⟸   NM_001270978
- Peptide Label: isoform e
- UniProtKB: P53990 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257908   ⟸   NM_001270979
- Peptide Label: isoform e
- UniProtKB: B4DXC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000455860   ⟸   ENST00000541571
RefSeq Acc Id: ENSP00000455805   ⟸   ENST00000541918
RefSeq Acc Id: ENSP00000398505   ⟸   ENST00000424485
RefSeq Acc Id: ENSP00000410081   ⟸   ENST00000439924
RefSeq Acc Id: ENSP00000457844   ⟸   ENST00000544564
RefSeq Acc Id: ENSP00000486751   ⟸   ENST00000626438
RefSeq Acc Id: ENSP00000454541   ⟸   ENST00000534994
RefSeq Acc Id: ENSP00000438399   ⟸   ENST00000535424
RefSeq Acc Id: ENSP00000368076   ⟸   ENST00000378799
RefSeq Acc Id: ENSP00000368075   ⟸   ENST00000378798
RefSeq Acc Id: ENSP00000414942   ⟸   ENST00000456820
RefSeq Acc Id: ENSP00000463833   ⟸   ENST00000536027
RefSeq Acc Id: ENSP00000457646   ⟸   ENST00000537613
RefSeq Acc Id: ENSP00000455590   ⟸   ENST00000538104
RefSeq Acc Id: ENSP00000463711   ⟸   ENST00000538850
RefSeq Acc Id: ENSP00000455757   ⟸   ENST00000539186
RefSeq Acc Id: ENSP00000330408   ⟸   ENST00000329908
RefSeq Acc Id: ENSP00000475853   ⟸   ENST00000606369
RefSeq Acc Id: ENSP00000455409   ⟸   ENST00000540296
RefSeq Acc Id: ENSP00000456200   ⟸   ENST00000568581

Promoters
RGD ID:6792749
Promoter ID:HG_KWN:24213
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000378798,   OTTHUMT00000269005,   OTTHUMT00000269006,   UC002FBN.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361670,486,581 - 70,487,081 (+)MPROMDB
RGD ID:6852016
Promoter ID:EP73814
Type:multiple initiation site
Name:HS_KIAA0174
Description:KIAA0174 gene product.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361670,507,024 - 70,507,084EPD
RGD ID:7232793
Promoter ID:EPDNEW_H22142
Type:initiation region
Name:IST1_1
Description:IST1, ESCRT-III associated factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,895,537 - 71,895,597EPDNEW
RGD ID:7232795
Promoter ID:EPDNEW_H22143
Type:initiation region
Name:KIAA0174_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381671,915,620 - 71,915,680EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 16q22.1-24.3(chr16:70514631-90081985)x3 copy number gain See cases [RCV000052422] Chr16:70514631..90081985 [GRCh38]
Chr16:70548534..90148393 [GRCh37]
Chr16:69106035..88675894 [NCBI36]
Chr16:16q22.1-24.3
pathogenic
GRCh38/hg38 16q21-23.1(chr16:58456122-74708723)x3 copy number gain See cases [RCV000052408] Chr16:58456122..74708723 [GRCh38]
Chr16:58490026..74742621 [GRCh37]
Chr16:57047527..73300122 [NCBI36]
Chr16:16q21-23.1
pathogenic
GRCh38/hg38 16q21-24.3(chr16:65313395-90081985)x3 copy number gain See cases [RCV000052421] Chr16:65313395..90081985 [GRCh38]
Chr16:65347298..90148393 [GRCh37]
Chr16:63904799..88675894 [NCBI36]
Chr16:16q21-24.3
pathogenic
GRCh38/hg38 16q22.1-23.1(chr16:69918076-76723348)x1 copy number loss See cases [RCV000053356] Chr16:69918076..76723348 [GRCh38]
Chr16:69951979..76757245 [GRCh37]
Chr16:68509480..75314746 [NCBI36]
Chr16:16q22.1-23.1
pathogenic
GRCh38/hg38 16q22.1-23.1(chr16:68698941-74353205)x1 copy number loss See cases [RCV000053337] Chr16:68698941..74353205 [GRCh38]
Chr16:68732844..74387103 [GRCh37]
Chr16:67290345..72944604 [NCBI36]
Chr16:16q22.1-23.1
pathogenic
GRCh38/hg38 16q22.2-22.3(chr16:71279916-73246687)x3 copy number gain See cases [RCV000053867] Chr16:71279916..73246687 [GRCh38]
Chr16:71313819..73280586 [GRCh37]
Chr16:69871320..71838087 [NCBI36]
Chr16:16q22.2-22.3
uncertain significance
GRCh38/hg38 16q22.1-24.1(chr16:70414573-84908120)x1 copy number loss See cases [RCV000133814] Chr16:70414573..84908120 [GRCh38]
Chr16:70448476..84941726 [GRCh37]
Chr16:69005977..83499227 [NCBI36]
Chr16:16q22.1-24.1
pathogenic
GRCh38/hg38 16q21-24.1(chr16:62925929-84585795)x3 copy number gain See cases [RCV000135863] Chr16:62925929..84585795 [GRCh38]
Chr16:62959833..84619401 [GRCh37]
Chr16:61517334..83176902 [NCBI36]
Chr16:16q21-24.1
pathogenic
GRCh38/hg38 16q22.1-24.3(chr16:70749398-90096995)x3 copy number gain See cases [RCV000137495] Chr16:70749398..90096995 [GRCh38]
Chr16:70783301..90163403 [GRCh37]
Chr16:69340802..88690904 [NCBI36]
Chr16:16q22.1-24.3
pathogenic
GRCh38/hg38 16q21-24.3(chr16:65511483-90096995)x3 copy number gain See cases [RCV000139426] Chr16:65511483..90096995 [GRCh38]
Chr16:65545386..90163403 [GRCh37]
Chr16:64102887..88690904 [NCBI36]
Chr16:16q21-24.3
pathogenic
GRCh38/hg38 16q22.1-23.3(chr16:69053457-83274681)x3 copy number gain See cases [RCV000142038] Chr16:69053457..83274681 [GRCh38]
Chr16:69087360..83308286 [GRCh37]
Chr16:67644861..81865787 [NCBI36]
Chr16:16q22.1-23.3
pathogenic
GRCh38/hg38 16q21-24.3(chr16:64389378-90081985)x3 copy number gain See cases [RCV000142578] Chr16:64389378..90081985 [GRCh38]
Chr16:64423281..90148393 [GRCh37]
Chr16:62980782..88675894 [NCBI36]
Chr16:16q21-24.3
pathogenic|likely pathogenic
GRCh38/hg38 16q12.2-24.3(chr16:52899183-90088654)x3 copy number gain See cases [RCV000143425] Chr16:52899183..90088654 [GRCh38]
Chr16:52933095..90155062 [GRCh37]
Chr16:51490596..88682563 [NCBI36]
Chr16:16q12.2-24.3
pathogenic
GRCh38/hg38 16q21-23.3(chr16:65957829-83611443)x3 copy number gain See cases [RCV000143742] Chr16:65957829..83611443 [GRCh38]
Chr16:65991732..83645048 [GRCh37]
Chr16:64549233..82202549 [NCBI36]
Chr16:16q21-23.3
pathogenic
GRCh37/hg19 16q11.2-24.3(chr16:46615804-90142285)x1 copy number loss Ductal breast carcinoma [RCV000207138] Chr16:46615804..90142285 [GRCh37]
Chr16:16q11.2-24.3
uncertain significance
GRCh37/hg19 16q22.2(chr16:71103288-72092204)x1 copy number loss Ductal breast carcinoma [RCV000207278] Chr16:71103288..72092204 [GRCh37]
Chr16:16q22.2
uncertain significance
Single allele complex Ductal breast carcinoma [RCV000207314] Chr16:56368689..90141355 [GRCh37]
Chr16:16q12.2-24.3
uncertain significance
GRCh37/hg19 16q11.2-24.3(chr16:46464488-90155062)x3 copy number gain See cases [RCV000446110] Chr16:46464488..90155062 [GRCh37]
Chr16:16q11.2-24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:69193-90274381)x3 copy number gain See cases [RCV000446684] Chr16:69193..90274381 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16q22.2(chr16:71218580-72049481)x1 copy number loss See cases [RCV000447076] Chr16:71218580..72049481 [GRCh37]
Chr16:16q22.2
uncertain significance
GRCh37/hg19 16p13.2-q24.3(chr16:9273328-89548493)x3 copy number gain See cases [RCV000511622] Chr16:9273328..89548493 [GRCh37]
Chr16:16p13.2-q24.3
uncertain significance
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062) copy number gain See cases [RCV000511296] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)x3 copy number gain See cases [RCV000512138] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16q11.2-24.3(chr16:46497599-90354753)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626429] Chr16:46497599..90354753 [GRCh37]
Chr16:16q11.2-24.3
drug response
GRCh37/hg19 16q11.2-24.3(chr16:46455960-90354753)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626435] Chr16:46455960..90354753 [GRCh37]
Chr16:16q11.2-24.3
drug response
GRCh37/hg19 16q13-24.3(chr16:57051473-89797669)x3 copy number gain See cases [RCV000512511] Chr16:57051473..89797669 [GRCh37]
Chr16:16q13-24.3
pathogenic
GRCh37/hg19 16q12.2-22.2(chr16:54416050-72453266)x3 copy number gain not provided [RCV000683820] Chr16:54416050..72453266 [GRCh37]
Chr16:16q12.2-22.2
pathogenic
GRCh37/hg19 16q22.1-22.2(chr16:70646969-72849701)x1 copy number loss not provided [RCV000683827] Chr16:70646969..72849701 [GRCh37]
Chr16:16q22.1-22.2
likely pathogenic
GRCh37/hg19 16q22.2-22.3(chr16:71561717-73724195)x1 copy number loss not provided [RCV000683830] Chr16:71561717..73724195 [GRCh37]
Chr16:16q22.2-22.3
likely pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90274695)x3 copy number gain not provided [RCV000738918] Chr16:88165..90274695 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:61451-90294632)x3 copy number gain not provided [RCV000738915] Chr16:61451..90294632 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90163275)x3 copy number gain not provided [RCV000738917] Chr16:88165..90163275 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16q22.2(chr16:71656661-72029303)x3 copy number gain not provided [RCV000751732] Chr16:71656661..72029303 [GRCh37]
Chr16:16q22.2
benign
GRCh37/hg19 16q22.2(chr16:71697752-72032231)x1 copy number loss not provided [RCV000751733] Chr16:71697752..72032231 [GRCh37]
Chr16:16q22.2
benign
NM_001270975.2(IST1):c.759+9_759+10insAG insertion not provided [RCV000947713] Chr16:71922689..71922690 [GRCh38]
Chr16:71956592..71956593 [GRCh37]
Chr16:16q22.2
benign
GRCh37/hg19 16q22.2(chr16:71822938-71974755)x1 copy number loss not provided [RCV001006801] Chr16:71822938..71974755 [GRCh37]
Chr16:16q22.2
uncertain significance
NM_001270975.2(IST1):c.510A>G (p.Ala170=) single nucleotide variant not provided [RCV000955515] Chr16:71921411 [GRCh38]
Chr16:71955314 [GRCh37]
Chr16:16q22.2
benign
GRCh37/hg19 16q21-24.3(chr16:61524229-90155062)x3 copy number gain not provided [RCV001249359] Chr16:61524229..90155062 [GRCh37]
Chr16:16q21-24.3
not provided

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:28977 AgrOrtholog
COSMIC IST1 COSMIC
Ensembl Genes ENSG00000182149 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000330408 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000368075 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000368076 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000398505 UniProtKB/TrEMBL
  ENSP00000410081 UniProtKB/TrEMBL
  ENSP00000414942 UniProtKB/TrEMBL
  ENSP00000438399 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000454541 UniProtKB/TrEMBL
  ENSP00000455409 UniProtKB/TrEMBL
  ENSP00000455590 UniProtKB/TrEMBL
  ENSP00000455757 UniProtKB/TrEMBL
  ENSP00000455805 UniProtKB/TrEMBL
  ENSP00000455860 UniProtKB/Swiss-Prot
  ENSP00000456200 UniProtKB/TrEMBL
  ENSP00000457646 UniProtKB/TrEMBL
  ENSP00000457844 UniProtKB/Swiss-Prot
  ENSP00000463711 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000463833 UniProtKB/TrEMBL
  ENSP00000475853 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000486751 UniProtKB/TrEMBL
Ensembl Transcript ENST00000329908 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000378798 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000378799 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000424485 UniProtKB/TrEMBL
  ENST00000439924 UniProtKB/TrEMBL
  ENST00000456820 UniProtKB/TrEMBL
  ENST00000534994 UniProtKB/TrEMBL
  ENST00000535424 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000536027 UniProtKB/TrEMBL
  ENST00000537613 UniProtKB/TrEMBL
  ENST00000538104 UniProtKB/TrEMBL
  ENST00000538850 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000539186 UniProtKB/TrEMBL
  ENST00000540296 UniProtKB/TrEMBL
  ENST00000541571 UniProtKB/Swiss-Prot
  ENST00000541918 UniProtKB/TrEMBL
  ENST00000544564 UniProtKB/Swiss-Prot
  ENST00000568581 UniProtKB/TrEMBL
  ENST00000606369 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000626438 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1260.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000182149 GTEx
HGNC ID HGNC:28977 ENTREZGENE
Human Proteome Map IST1 Human Proteome Map
InterPro Ist1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IST1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:9798 UniProtKB/Swiss-Prot
NCBI Gene 9798 ENTREZGENE
OMIM 616434 OMIM
PANTHER PTHR12161 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ist1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142671633 PharmGKB
UniProt B4DXC9 ENTREZGENE, UniProtKB/TrEMBL
  E9PF00_HUMAN UniProtKB/TrEMBL
  F5GXM3_HUMAN UniProtKB/TrEMBL
  H3BMU1_HUMAN UniProtKB/TrEMBL
  H3BPP6_HUMAN UniProtKB/TrEMBL
  H3BQ38_HUMAN UniProtKB/TrEMBL
  H3BQF7_HUMAN UniProtKB/TrEMBL
  H3BRE2_HUMAN UniProtKB/TrEMBL
  H3BUI0_HUMAN UniProtKB/TrEMBL
  IST1_HUMAN UniProtKB/Swiss-Prot
  J3KR23_HUMAN UniProtKB/TrEMBL
  J3QQP8_HUMAN UniProtKB/TrEMBL
  P53990 ENTREZGENE
UniProt Secondary A8KAH5 UniProtKB/Swiss-Prot
  J3QLU7 UniProtKB/Swiss-Prot
  Q3SYM4 UniProtKB/Swiss-Prot
  Q9BQ81 UniProtKB/Swiss-Prot
  Q9BWN2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-05 IST1  IST1 factor associated with ESCRT-III    IST1, ESCRT-III associated factor  Symbol and/or name change 5135510 APPROVED
2016-02-29 IST1  IST1, ESCRT-III associated factor    increased sodium tolerance 1 homolog (yeast)  Symbol and/or name change 5135510 APPROVED
2012-08-21 IST1  increased sodium tolerance 1 homolog (yeast)  IST1  increased sodium tolerance 1 homolog (yeast)  Symbol and/or name change 5135510 APPROVED
2011-08-23 IST1  increased sodium tolerance 1 homolog (yeast)  KIAA0174  KIAA0174  Symbol and/or name change 5135510 APPROVED