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Gene: TRIOBP (TRIO and F-actin binding protein) Homo sapiens
Symbol: TRIOBP
Name: TRIO and F-actin binding protein
Description: Exhibits actin filament binding activity and ubiquitin protein ligase binding activity. Involved in positive regulation of substrate adhesion-dependent cell spreading. Localizes to actin cytoskeleton. Implicated in autosomal recessive nonsyndromic deafness 28.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deafness, autosomal recessive 28; DFNB28; dJ37E16.4; FLJ39315; HRIHFB2122; KIAA1662; TAP68; TARA; tara-like protein; TRIO and F-actin-binding protein; trio-associated repeat on actin
Mus musculus (house mouse) : Triobp (TRIO and F-actin binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Triobp (TRIO and F-actin binding protein)  Alliance
Canis lupus familiaris (dog) : TRIOBP (TRIO and F-actin binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Triobp (TRIO and F-actin binding protein)
Sus scrofa (pig) : TRIOBP (TRIO and F-actin binding protein)
Heterocephalus glaber (naked mole-rat) : Triobp (TRIO and F-actin binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2237,697,048 - 37,776,556 (+)EnsemblGRCh38hg38GRCh38
GRCh382237,697,048 - 37,776,556 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372238,092,995 - 38,172,563 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,423,574 - 36,502,509 (+)NCBINCBI36hg18NCBI36
Celera2221,894,838 - 21,974,375 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2221,059,927 - 21,139,806 (+)NCBIHuRef
CHM1_12238,051,700 - 38,131,297 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TRIOBP
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605399
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.