STK40 (serine/threonine kinase 40)

Gene: STK40 (serine/threonine kinase 40) Homo sapiens

Analyze

Symbol:

STK40

Name:

serine/threonine kinase 40

RGD ID:

1605028

HGNC Page

HGNC:21373

Description:

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to act upstream of or within several processes, including glycogen metabolic process; lung development; and respiratory system process. Located in cytosol and nucleoplasm.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

2310004N11Rik; MGC4796; RP11-268J15.4; Ser/Thr-like kinase; serine/threonine-protein kinase 40; SgK495; SHIK; SINK-homologous serine/threonine-protein kinase; sugen kinase 495

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Stk40 (serine/threonine kinase 40)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Stk40 (serine/threonine kinase 40)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Chinchilla lanigera (long-tailed chinchilla):	Stk40 (serine/threonine kinase 40)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	STK40 (serine/threonine kinase 40)	NCBI	Ortholog
Canis lupus familiaris (dog):	STK40 (serine/threonine kinase 40)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Stk40 (serine/threonine kinase 40)	NCBI	Ortholog
Sus scrofa (pig):	STK40 (serine/threonine kinase 40)	HGNC	Ensembl, NCBI, OrthoDB
Chlorocebus sabaeus (green monkey):	STK40 (serine/threonine kinase 40)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Stk40 (serine/threonine kinase 40)	NCBI	Ortholog
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Stk40 (serine/threonine kinase 40)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Stk40 (serine/threonine kinase 40)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	stk40 (serine/threonine kinase 40)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	stk40	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	stk40.S	Alliance	DIOPT (Xenbase)
Xenopus laevis (African clawed frog):	stk40.L	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	36,339,628 - 36,385,924 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	36,339,624 - 36,385,924 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	36,805,229 - 36,851,525 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	36,577,812 - 36,624,072 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	35,080,354 - 35,126,619 (-)	NCBI		Celera
Cytogenetic Map	1	p34.3	NCBI
HuRef	1	34,921,985 - 34,968,132 (-)	NCBI		HuRef
CHM1_1	1	36,921,399 - 36,967,662 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	36,202,501 - 36,248,808 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (IAGP)

genetic disease (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (ISO)

2-methylcholine (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

arsane (EXP)

arsenic atom (EXP)

benzene (EXP)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbamazepine (EXP)

CGP 52608 (EXP)

chlorpyrifos (ISO)

chromium(6+) (EXP)

cobalt dichloride (ISO)

cocaine (ISO)

copper(II) sulfate (EXP)

Cuprizon (ISO)

cyclosporin A (EXP)

dibutyl phthalate (ISO)

diquat (ISO)

doxorubicin (EXP)

entinostat (EXP)

fenthion (ISO)

fluoranthene (ISO)

furan (ISO)

gentamycin (ISO)

hydroquinone (EXP)

methidathion (ISO)

methimazole (ISO)

methylmercury chloride (EXP)

ozone (EXP)

paracetamol (EXP,ISO)

phenobarbital (EXP,ISO)

pirinixic acid (ISO)

potassium chromate (EXP)

Soman (ISO)

sulfadimethoxine (ISO)

sunitinib (EXP)

temozolomide (EXP)

tetrachloromethane (ISO)

thioacetamide (ISO)

tungsten (ISO)

valproic acid (EXP,ISO)

zinc atom (EXP)

zinc(0) (EXP)

zoledronic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glycogen metabolic process (IEA,ISO)

lung alveolus development (IEA,ISO)

lung development (IEA,ISO)

lung morphogenesis (IEA,ISO)

multicellular organism growth (IEA,ISO)

negative regulation of apoptotic process (IEA,ISO)

regulation of gene expression (IEA,ISO)

regulation of MAPK cascade (IEA,ISO)

respiratory system process (IEA,ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IDA)

nucleoplasm (IDA)

nucleus (IEA)

Molecular Function

ATP binding (IEA)

protein binding (IPI)

protein kinase activity (IEA)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11076863	PMID:11230166	PMID:12477932	PMID:13679039	PMID:14702039	PMID:15489334	PMID:15489336	PMID:16169070	PMID:16344560	PMID:16381901	PMID:16710414	PMID:18029348
PMID:19953087	PMID:21784977	PMID:21832049	PMID:23226273	PMID:23233723	PMID:24447338	PMID:24510904	PMID:25609649	PMID:25852190	PMID:26186194	PMID:26344197	PMID:26496610
PMID:28089446	PMID:28419554	PMID:28514442	PMID:32296183	PMID:32707033	PMID:33961781	PMID:35140242	PMID:35748872	PMID:37689310	PMID:37915566

Genomics

Comparative Map Data

STK40
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	36,339,628 - 36,385,924 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	36,339,624 - 36,385,924 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	36,805,229 - 36,851,525 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	36,577,812 - 36,624,072 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	35,080,354 - 35,126,619 (-)	NCBI		Celera
Cytogenetic Map	1	p34.3	NCBI
HuRef	1	34,921,985 - 34,968,132 (-)	NCBI		HuRef
CHM1_1	1	36,921,399 - 36,967,662 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	36,202,501 - 36,248,808 (-)	NCBI		T2T-CHM13v2.0

Stk40
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	125,997,738 - 126,034,822 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	125,997,750 - 126,034,822 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	126,103,942 - 126,141,029 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	126,103,957 - 126,141,029 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	125,781,201 - 125,818,273 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	125,606,302 - 125,643,186 (+)	NCBI		MGSCv36	mm8
Celera	4	124,434,390 - 124,471,601 (+)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	59.89	NCBI

Stk40
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	143,660,438 - 143,702,336 (+)	NCBI		GRCr8
mRatBN7.2	5	138,380,049 - 138,417,802 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	138,381,159 - 138,417,796 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	141,091,338 - 141,127,768 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	142,861,353 - 142,897,785 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	142,862,520 - 142,898,947 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	144,112,612 - 144,150,653 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	144,114,012 - 144,150,647 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	147,882,697 - 147,920,188 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	145,457,719 - 145,494,354 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	145,467,710 - 145,504,226 (+)	NCBI
Celera	5	136,891,355 - 136,927,933 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Stk40
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	14,301,533 - 14,345,988 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	14,298,759 - 14,345,293 (-)	NCBI	ChiLan1.0	ChiLan1.0

STK40
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	190,458,775 - 190,504,982 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	189,580,004 - 189,626,203 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	35,607,231 - 35,653,443 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	36,775,581 - 36,821,654 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	36,775,581 - 36,821,654 (-)	Ensembl	panpan1.1		panPan2

STK40
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	5,894,125 - 5,934,461 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	5,894,933 - 5,932,791 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	6,136,970 - 6,176,979 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	6,029,736 - 6,069,743 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	6,030,291 - 6,069,741 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	5,883,149 - 5,923,136 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	5,950,874 - 5,990,846 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	5,965,960 - 6,005,961 (+)	NCBI		UU_Cfam_GSD_1.0

Stk40
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	52,946,652 - 52,991,269 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	18,771,358 - 18,816,098 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	18,771,434 - 18,816,086 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STK40
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	92,441,233 - 92,484,336 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	92,441,231 - 92,484,363 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

STK40
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	96,473,456 - 96,520,683 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	96,473,527 - 96,520,769 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	20,217,574 - 20,265,834 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Stk40
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	19,255,300 - 19,287,162 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	19,255,300 - 19,298,956 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in STK40
18 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 1p36.11-34.2(chr1:24381206-41401517)x3	copy number gain	See cases [RCV000138891]	Chr1:24381206..41401517 [GRCh38] Chr1:24707696..41886350 [GRCh37] Chr1:24580283..41658937 [NCBI36] Chr1:1p36.11-34.2	pathogenic
GRCh38/hg38 1p34.3(chr1:35934217-36821999)x4	copy number gain	See cases [RCV000138892]	Chr1:35934217..36821999 [GRCh38] Chr1:36399818..37287600 [GRCh37] Chr1:36172405..37060187 [NCBI36] Chr1:1p34.3	likely pathogenic
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3	copy number loss	not provided [RCV000762767]	Chr1:20608823..120546301 [GRCh37] Chr1:1p36.12-12	likely benign
GRCh37/hg19 1p34.3(chr1:34830287-36945093)x1	copy number loss	See cases [RCV000448022]	Chr1:34830287..36945093 [GRCh37] Chr1:1p34.3	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3	copy number gain	See cases [RCV000510383]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
NC_000001.10:g.(?_33241563)_(46663513_?)dup	duplication	Charcot-Marie-Tooth disease dominant intermediate C [RCV000708276]	Chr1:33241563..46663513 [GRCh37] Chr1:1p35.1-34.1	uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)	copy number gain	See cases [RCV000510926]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3	copy number gain	not provided [RCV000736295]	Chr1:47851..249228449 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3	copy number gain	not provided [RCV000736305]	Chr1:82154..249218992 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p35.2-34.3(chr1:31562164-37421958)x3	copy number gain	not provided [RCV000748949]	Chr1:31562164..37421958 [GRCh37] Chr1:1p35.2-34.3	pathogenic
NM_001282547.2(STK40):c.1101G>A (p.Thr367=)	single nucleotide variant	not provided [RCV000965549]	Chr1:36341962 [GRCh38] Chr1:36807563 [GRCh37] Chr1:1p34.3	benign
NM_001282547.2(STK40):c.879T>C (p.Ile293=)	single nucleotide variant	not provided [RCV000965550]	Chr1:36344125 [GRCh38] Chr1:36809726 [GRCh37] Chr1:1p34.3	benign
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3	copy number gain	Global developmental delay [RCV000787285]	Chr1:103343285..103455144 [GRCh37] Chr1:1p36.22-21.1	uncertain significance
GRCh37/hg19 1p34.3(chr1:36496921-36829945)x3	copy number gain	not provided [RCV000847964]	Chr1:36496921..36829945 [GRCh37] Chr1:1p34.3	uncertain significance
NC_000001.10:g.(?_33241563)_(46663513_?)dup	duplication	Charcot-Marie-Tooth disease, dominant intermediate C [RCV001308684]	Chr1:33241563..46663513 [GRCh37] Chr1:1p35.1-34.1	uncertain significance
GRCh37/hg19 1p34.3(chr1:36041366-39112237)	copy number loss	not specified [RCV002053236]	Chr1:36041366..39112237 [GRCh37] Chr1:1p34.3	uncertain significance
GRCh37/hg19 1p35.1-33(chr1:33285582-47891811)	copy number gain	not specified [RCV002052781]	Chr1:33285582..47891811 [GRCh37] Chr1:1p35.1-33	pathogenic
GRCh37/hg19 1p34.3(chr1:35104233-37357913)x1	copy number loss	not provided [RCV002474552]	Chr1:35104233..37357913 [GRCh37] Chr1:1p34.3	pathogenic
NM_001282547.2(STK40):c.305C>T (p.Thr102Met)	single nucleotide variant	Inborn genetic diseases [RCV002684609]	Chr1:36358276 [GRCh38] Chr1:36823877 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.868G>A (p.Glu290Lys)	single nucleotide variant	Inborn genetic diseases [RCV002734623]	Chr1:36344136 [GRCh38] Chr1:36809737 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.617A>G (p.Asn206Ser)	single nucleotide variant	Inborn genetic diseases [RCV002882741]	Chr1:36354370 [GRCh38] Chr1:36819971 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.41C>T (p.Ser14Leu)	single nucleotide variant	Inborn genetic diseases [RCV002705128]	Chr1:36361292 [GRCh38] Chr1:36826893 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.240C>G (p.Ser80Arg)	single nucleotide variant	Inborn genetic diseases [RCV002919543]	Chr1:36358341 [GRCh38] Chr1:36823942 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.460G>A (p.Ala154Thr)	single nucleotide variant	Inborn genetic diseases [RCV002827537]	Chr1:36355316 [GRCh38] Chr1:36820917 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.339C>A (p.Phe113Leu)	single nucleotide variant	Inborn genetic diseases [RCV002809829]	Chr1:36358242 [GRCh38] Chr1:36823843 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.167A>G (p.Lys56Arg)	single nucleotide variant	Inborn genetic diseases [RCV002807412]	Chr1:36358768 [GRCh38] Chr1:36824369 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.1198C>A (p.Pro400Thr)	single nucleotide variant	Inborn genetic diseases [RCV002940563]	Chr1:36341865 [GRCh38] Chr1:36807466 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.1235G>A (p.Arg412Gln)	single nucleotide variant	Inborn genetic diseases [RCV002722944]	Chr1:36341828 [GRCh38] Chr1:36807429 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.1213G>A (p.Gly405Ser)	single nucleotide variant	Inborn genetic diseases [RCV003280807]	Chr1:36341850 [GRCh38] Chr1:36807451 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.347G>A (p.Arg116His)	single nucleotide variant	Inborn genetic diseases [RCV003192336]	Chr1:36355429 [GRCh38] Chr1:36821030 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.161C>T (p.Ala54Val)	single nucleotide variant	Inborn genetic diseases [RCV003283088]	Chr1:36358774 [GRCh38] Chr1:36824375 [GRCh37] Chr1:1p34.3	uncertain significance
NM_001282547.2(STK40):c.331G>A (p.Gly111Ser)	single nucleotide variant	Inborn genetic diseases [RCV003369362]	Chr1:36358250 [GRCh38] Chr1:36823851 [GRCh37] Chr1:1p34.3	uncertain significance
Single allele	inversion	Bilateral polymicrogyria [RCV003459046]	Chr1:33246132..61045156 [GRCh38] Chr1:1p35.1-31.3	likely pathogenic
NM_001282547.2(STK40):c.438T>C (p.Ala146=)	single nucleotide variant	not provided [RCV003406347]	Chr1:36355338 [GRCh38] Chr1:36820939 [GRCh37] Chr1:1p34.3	likely benign

miRNA Target Status

Confirmed Target Of

miRNA Gene	Mature miRNA	Method Name	Result Type	Data Type	Support Type	PMID
MIR940	hsa-miR-940	Mirtarbase	external_info	CLASH	Functional MTI (Weak)	23622248
MIR31	hsa-miR-31-5p	Mirtarbase	external_info	Luciferase reporter assay	Functional MTI	23233723

Predicted Target Of

	Summary Value
Count of predictions:	10107
Count of miRNA genes:	1154
Interacting mature miRNAs:	1467
Transcripts:	ENST00000359297, ENST00000373129, ENST00000373130, ENST00000373132, ENST00000460017, ENST00000460417, ENST00000473733, ENST00000482458
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

SHGC-142395

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	36,833,178 - 36,833,486	UniSTS	GRCh37
Build 36	1	36,605,765 - 36,606,073	RGD	NCBI36
Celera	1	35,108,312 - 35,108,620	RGD
Cytogenetic Map	1	p34.3	UniSTS
HuRef	1	34,949,947 - 34,950,255	UniSTS
TNG Radiation Hybrid Map	1	17651.0	UniSTS

A008P26

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	36,807,167 - 36,807,371	UniSTS	GRCh37
Build 36	1	36,579,754 - 36,579,958	RGD	NCBI36
Celera	1	35,082,296 - 35,082,500	RGD
Cytogenetic Map	1	p34.3	UniSTS
HuRef	1	34,923,927 - 34,924,131	UniSTS
GeneMap99-GB4 RH Map	1	111.15	UniSTS
NCBI RH Map	1	251.9	UniSTS

SHGC-74578

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	36,807,097 - 36,807,229	UniSTS	GRCh37
Build 36	1	36,579,684 - 36,579,816	RGD	NCBI36
Celera	1	35,082,226 - 35,082,358	RGD
Cytogenetic Map	1	p34.3	UniSTS
HuRef	1	34,923,857 - 34,923,989	UniSTS
TNG Radiation Hybrid Map	1	17626.0	UniSTS
GeneMap99-GB4 RH Map	1	109.51	UniSTS
Whitehead-RH Map	1	110.9	UniSTS
NCBI RH Map	1	233.4	UniSTS

SHGC-74593

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	36,805,376 - 36,805,504	UniSTS	GRCh37
Build 36	1	36,577,963 - 36,578,091	RGD	NCBI36
Celera	1	35,080,505 - 35,080,633	RGD
Cytogenetic Map	1	p34.3	UniSTS
HuRef	1	34,922,136 - 34,922,264	UniSTS
TNG Radiation Hybrid Map	1	17626.0	UniSTS
GeneMap99-GB4 RH Map	1	110.37	UniSTS
NCBI RH Map	1	228.6	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

High

Medium

2420

2856

1635

579

1918

421

4349

2092

2458

389

1440

1602

171

1204

2787

Low

130

101

1253

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001282546	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001282547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_032017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK000808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK024504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK075029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK075048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK131560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL591845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL834137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AW269508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY198395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC005169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC007835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC008344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CQ834750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CQ834752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA375448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KT585098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000359297 ⟹ ENSP00000352245

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,339,624 - 36,361,340 (-)	Ensembl

RefSeq Acc Id:

ENST00000373129 ⟹ ENSP00000362221

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,339,624 - 36,385,884 (-)	Ensembl

RefSeq Acc Id:

ENST00000373130 ⟹ ENSP00000362222

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,339,624 - 36,385,888 (-)	Ensembl

RefSeq Acc Id:

ENST00000373132 ⟹ ENSP00000362224

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,339,628 - 36,385,924 (-)	Ensembl

RefSeq Acc Id:

ENST00000460017

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,367,854 - 36,385,876 (-)	Ensembl

RefSeq Acc Id:

ENST00000460417

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,355,205 - 36,366,072 (-)	Ensembl

RefSeq Acc Id:

ENST00000473733

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,355,253 - 36,362,656 (-)	Ensembl

RefSeq Acc Id:

ENST00000482458

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	36,355,289 - 36,385,879 (-)	Ensembl

RefSeq Acc Id:

NM_001282546 ⟹ NP_001269475

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	36,339,628 - 36,385,924 (-)	NCBI
HuRef	1	34,921,980 - 34,968,175 (-)	NCBI
CHM1_1	1	36,921,394 - 36,967,705 (-)	NCBI
T2T-CHM13v2.0	1	36,202,501 - 36,248,808 (-)	NCBI

Sequence:

show sequence

ACTTCCGTTGTCAGGTGGCGGCGCCGCAGCCATGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGC
TCGGGTGGCTGCGCTGGGAGGCGGCGGTGAGAGGCTCGCACGCCTCCAGCCCGGCCCCGGCCCC
CCGGGAGGGAGAGCCGAGCAGCCCCGGCTCTGGGCTACGGACTATGGGCGAATAGCTCTGACCA
CCCGGCGAAGAGCTGAGAATGAAGCGGAGAGCATCAGACAGAGGAGCTGGGGAAACGTCGGCCA
GGGCCAAGGCTCTAGGAAGTGGGATTTCTGGAAATAATGCAAAGAGAGCTGGACCATTCATCCT
TGCTCTCTGTGCCGTAGGTCCCCGTCTGGGCAACTCACCGGTGCCAAGCATAGTGCAGTGTTTG
GCGAGGAAAGATGGCACGGATGACTTCTATCAGCTGAAGATCCTGACCCTGGAGGAGAGGGGGG
ACCAAGGCATAGAGAGCCAGGAAGAGCGGCAGGGCAAGATGCTGCTGCACACCGAGTACTCACT
GCTGTCTCTCCTGCACACGCAGGATGGCGTGGTGCACCACCACGGCCTCTTCCAGGACCGCACC
TGTGAAATCGTTGAGGACACAGAATCCAGCCGGATGGTTAAGAAGATGAAGAAGCGCATCTGCC
TCGTCCTGGACTGCCTCTGTGCTCATGACTTCAGCGATAAGACCGCTGACCTCATCAACCTGCA
GCACTACGTCATCAAGGAGAAGAGGCTCAGCGAGAGGGAGACTGTGGTAATCTTCTACGACGTG
GTCCGCGTGGTGGAGGCCCTGCACCAGAAAAATATCGTGCACAGAGACCTGAAGCTGGGGAACA
TGGTGCTCAACAAGAGGACACATCGGATAACCATCACCAACTTCTGCCTCGGGAAGCATCTGGT
GAGCGAGGGGGACCTGCTGAAGGACCAGAGAGGGAGCCCTGCCTACATCAGTCCCGACGTGCTC
AGCGGCCGGCCGTACCGTGGCAAGCCCAGTGACATGTGGGCCCTGGGCGTGGTGCTCTTCACCA
TGCTGTATGGCCAGTTCCCCTTCTACGACAGCATCCCGCAGGAGCTCTTCCGCAAGATCAAGGC
TGCCGAGTATACCATTCCTGAGGATGGACGGGTTTCTGAGAACACCGTGTGTCTCATCCGGAAG
CTGCTGGTCCTTGACCCCCAGCAGCGCCTGGCCGCCGCCGACGTCCTGGAGGCCCTCAGTGCCA
TCATTGCATCATGGCAGTCCCTGTCATCTCTGAGTGGGCCTTTGCAAGTGGTTCCTGACATTGA
TGACCAAATGAGCAATGCGGATAGCTCCCAGGAGGCGAAGGTGACGGAGGAGTGCTCCCAGTAC
GAGTTTGAGAACTACATGCGTCAGCAGCTGCTGCTGGCCGAGGAGAAGAGCTCCATCCATGACG
CCCGGAGCTGGGTACCCAAGCGGCAGTTCGGCAGCGCACCACCGGTGCGACGGCTGGGCCACGA
CGCACAGCCCATGACCTCCTTGGACACGGCCATCCTGGCGCAGCGCTACCTGCGGAAATAACAG
CCTCAGCCGGGGCCACCAGCACTGCTGCCACTTCTTCCAGCCCCAGCCAAAGGCGTGGCTGTCA
GGGCTGGGCCCTGTAGTGCTGGACTCTCCCGGGCCACAATAGGGACAGGGCAGGGACAGGGACA
GCCCAGGTCACACGTGGGGTCAGCAGAGGTACCACGAAGCTACCTTTTGGGATGATTGCTCGAT
TGTTTGGTTTTTAAATCTGAGAAGCCTAGATAACTAATCTGCTTTTAATCACGATGTTTTAATC
TACCTCTGTCTCTTTAACCATGCTGTCTCTGGACTGAGCAAGAGGGAGGAGGGAGCCTGCTCAC
CCCACTCCAGGGCCTTCCCCAGCGGCCACCAACTGACCTGGGGCGCTGCTCCCCACAGTCCAAA
TAAGCTGAAAGTGCAGCTCGCTGCAGGCCCCAGAGCGAGCTTCCCCTCCTCCCTGCTCTCCCAG
GCCCCTGCCACAGCCTCTTTCCGTCCCTCTCTTTCTGATCCAGGCCCCTCAGTCCAAGCTTTGG
AAAACCTTCACCTCATCTTAAACCGAACTCAAATATATTTATTTTTTTACCATACCAACTTCTC
TCCCATCTCTAGGTGGCTCAGTCCATGGCCACTCCCTGCCCCCAGCCTGGCTGGACAGCAAGGA
ATCCACAGCCCACACGTGAGCTCCCTCCTCACCCCCAGGCAGGGAAGCCCCTCCTGCCAGTCCC
TGTCCCCTTTCAGCCCACCAGTCCCTCTCTGCTGCCGGTGATGGGAGGCCTTTCTAGACCTGGC
TCTTTCTCTCCCGTCTCAGTGGCTTCTCTGAGGTGCTGTACACGCGCGTTAACCTGTTCCCTTC
TCTATCCTTCCCCGTGGTACTGAGCTCACGTGGACTCCCAGTGCGAAGGGGCCCATGGGTTGGG
CTGCAGGCCTGGCCGTGAGCGGGGGCTGCCTGCACGCTCCCCTAGCCTACTCTTGTGTTTAGGG
GATGGTGGGAACATATCCCAGTGCCCTTGCCTCATAATAGATGTGGTGACTCTCCCGGTAGACC
CTAGCAAGGGTCCTCCATGGTGGTGAGGGACTCAGGAGAATTGTAGGGATTGGGGGACCCTGCC
TGCCTGGCTTGAGAACAGCCCTGCTGCCCTTTTGAGCCGAGATTTTGAAGTGGATGCCCGTCTT
GCCAGAAATGCTGTTCTCACCAGAATGCCCCCTCCCCTTGCCCTTACTGGACTTGGCCCTGCCT
GATGCCAAGCAAAGACCCTTCCCCAGAGGCCTACCCCCCATATGTCCTCAGAGAGGCTGAGTGT
CCCCTCCAGGCAGTCATGGGCCCTGAGGCCCCTCCTGCCTGGCCCTGCTCCCCAGTGGGGAGGT
GACTGTGTTTCCCAGAGTGTGAGCCGCTCTCCTCCCCCTAAAAAGCTGACTCACTGTGAGTGAC
CTTGGGCAAGTTCCCAAACCTCCTTGTGCCTCAGTTTCCCCATCTGGAAAAAATGGGGCCACCT
CTTGCCAGCAGTAGCAGGGCTGCCCACGCCCCTTTCTCCCCATGCCCCATCCAGCACTTGGGCG
ACTCATGCCTCTGCCTCAGTGGGCCTGTGGGAGCCTACTGGAGCCCAGCACTTACTCCCCCTGA
GCAGCGAGCCTGCGTCTGTCTCAGCTGTCCAGCGCTGAGGGCCAGGGTCTTGTGCTGTGGGGCT
GGGGGATGCCCTCTTTTCTATATTTATTTCATAGAAAGTCTCCTGCGGGAGCGGAAATGCAGTC
CGGCCTAGGGCTCCCAGCCCTTGACTGTCCTCCTGTGAGGGCCTGAAGCTGGGCCAGGGCCCGT
CGCAGCGGAGCCCCCTCTCAGCAGCCCACCGGGTCCCTCCAGGCTGCTGCCCGTGCGTGGTCTT
TCTCCTCCTTTTCAAAGCAATAGCCGCCGGGTCTGCAAAGCCCTGTCAGACAGACTGGGCCCTT
CCAAGGTCAAGCCATGTGTCTGATGACATTCCTGGTGAAGCAAAGGAGAGGAGGATGGGTCAGC
CCTCACTGGGTGTCACACACTGAGAGAAGTCCTATTGTAAAGAAACGGAAAAAGTCACAAAAAA
GTTTGTATAAAGACATATTTTTGTACTACATGGGGACTCTTCCTGCATGTCAGCAATAAAACTT
CCTGATCTGGAA

hide sequence

RefSeq Acc Id:

NM_001282547 ⟹ NP_001269476

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	36,339,628 - 36,385,924 (-)	NCBI
HuRef	1	34,921,980 - 34,968,175 (-)	NCBI
CHM1_1	1	36,921,394 - 36,967,705 (-)	NCBI
T2T-CHM13v2.0	1	36,202,501 - 36,248,808 (-)	NCBI

Sequence:

show sequence

ACTTCCGTTGTCAGGTGGCGGCGCCGCAGCCATGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGC
TCGGGTGGCTGCGCTGGGAGGCGGCGGTGAGAGGCTCGCACGCCTCCAGCCCGGCCCCGGCCCC
CCGGGAGGGAGAGCCGAGCAGCCCCGGCTCTGGGCTACGGACTATGGGCGAATAGCTCTGACCA
CCCGGCGAAGAGCTGAGAATGAAGCGGAGAGCATCAGACAGAGGAGCTGGGGAAACGTCGGCCA
GGGCCAAGGCTCTAGGAAGTGGGATTTCTGGAAATAATGCAAAGAGAGCTGGACCATTCATCCT
TGGTCCCCGTCTGGGCAACTCACCGGTGCCAAGCATAGTGCAGTGTTTGGCGAGGAAAGATGGC
ACGGATGACTTCTATCAGCTGAAGATCCTGACCCTGGAGGAGAGGGGGGACCAAGGCATAGAGA
GCCAGGAAGAGCGGCAGGGCAAGATGCTGCTGCACACCGAGTACTCACTGCTGTCTCTCCTGCA
CACGCAGGATGGCGTGGTGCACCACCACGGCCTCTTCCAGGACCGCACCTGTGAAATCGTTGAG
GACACAGAATCCAGCCGGATGGTTAAGAAGATGAAGAAGCGCATCTGCCTCGTCCTGGACTGCC
TCTGTGCTCATGACTTCAGCGATAAGACCGCTGACCTCATCAACCTGCAGCACTACGTCATCAA
GGAGAAGAGGCTCAGCGAGAGGGAGACTGTGGTAATCTTCTACGACGTGGTCCGCGTGGTGGAG
GCCCTGCACCAGAAAAATATCGTGCACAGAGACCTGAAGCTGGGGAACATGGTGCTCAACAAGA
GGACACATCGGATAACCATCACCAACTTCTGCCTCGGGAAGCATCTGGTGAGCGAGGGGGACCT
GCTGAAGGACCAGAGAGGGAGCCCTGCCTACATCAGTCCCGACGTGCTCAGCGGCCGGCCGTAC
CGTGGCAAGCCCAGTGACATGTGGGCCCTGGGCGTGGTGCTCTTCACCATGCTGTATGGCCAGT
TCCCCTTCTACGACAGCATCCCGCAGGAGCTCTTCCGCAAGATCAAGGCTGCCGAGTATACCAT
TCCTGAGGATGGACGGGTTTCTGAGAACACCGTGTGTCTCATCCGGAAGCTGCTGGTCCTTGAC
CCCCAGCAGCGCCTGGCCGCCGCCGACGTCCTGGAGGCCCTCAGTGCCATCATTGCATCATGGC
AGTCCCTGTCATCTCTGAGTGGGCCTTTGCAAGTGGTTCCTGACATTGATGACCAAATGAGCAA
TGCGGATAGCTCCCAGGAGGCGAAGGTGACGGAGGAGTGCTCCCAGTACGAGTTTGAGAACTAC
ATGCGTCAGCAGCTGCTGCTGGCCGAGGAGAAGAGCTCCATCCATGACGCCCGGAGCTGGGTAC
CCAAGCGGCAGTTCGGCAGCGCACCACCGGTGCGACGGCTGGGCCACGACGCACAGCCCATGAC
CTCCTTGGACACGGCCATCCTGGCGCAGCGCTACCTGCGGAAATAACAGCCTCAGCCGGGGCCA
CCAGCACTGCTGCCACTTCTTCCAGCCCCAGCCAAAGGCGTGGCTGTCAGGGCTGGGCCCTGTA
GTGCTGGACTCTCCCGGGCCACAATAGGGACAGGGCAGGGACAGGGACAGCCCAGGTCACACGT
GGGGTCAGCAGAGGTACCACGAAGCTACCTTTTGGGATGATTGCTCGATTGTTTGGTTTTTAAA
TCTGAGAAGCCTAGATAACTAATCTGCTTTTAATCACGATGTTTTAATCTACCTCTGTCTCTTT
AACCATGCTGTCTCTGGACTGAGCAAGAGGGAGGAGGGAGCCTGCTCACCCCACTCCAGGGCCT
TCCCCAGCGGCCACCAACTGACCTGGGGCGCTGCTCCCCACAGTCCAAATAAGCTGAAAGTGCA
GCTCGCTGCAGGCCCCAGAGCGAGCTTCCCCTCCTCCCTGCTCTCCCAGGCCCCTGCCACAGCC
TCTTTCCGTCCCTCTCTTTCTGATCCAGGCCCCTCAGTCCAAGCTTTGGAAAACCTTCACCTCA
TCTTAAACCGAACTCAAATATATTTATTTTTTTACCATACCAACTTCTCTCCCATCTCTAGGTG
GCTCAGTCCATGGCCACTCCCTGCCCCCAGCCTGGCTGGACAGCAAGGAATCCACAGCCCACAC
GTGAGCTCCCTCCTCACCCCCAGGCAGGGAAGCCCCTCCTGCCAGTCCCTGTCCCCTTTCAGCC
CACCAGTCCCTCTCTGCTGCCGGTGATGGGAGGCCTTTCTAGACCTGGCTCTTTCTCTCCCGTC
TCAGTGGCTTCTCTGAGGTGCTGTACACGCGCGTTAACCTGTTCCCTTCTCTATCCTTCCCCGT
GGTACTGAGCTCACGTGGACTCCCAGTGCGAAGGGGCCCATGGGTTGGGCTGCAGGCCTGGCCG
TGAGCGGGGGCTGCCTGCACGCTCCCCTAGCCTACTCTTGTGTTTAGGGGATGGTGGGAACATA
TCCCAGTGCCCTTGCCTCATAATAGATGTGGTGACTCTCCCGGTAGACCCTAGCAAGGGTCCTC
CATGGTGGTGAGGGACTCAGGAGAATTGTAGGGATTGGGGGACCCTGCCTGCCTGGCTTGAGAA
CAGCCCTGCTGCCCTTTTGAGCCGAGATTTTGAAGTGGATGCCCGTCTTGCCAGAAATGCTGTT
CTCACCAGAATGCCCCCTCCCCTTGCCCTTACTGGACTTGGCCCTGCCTGATGCCAAGCAAAGA
CCCTTCCCCAGAGGCCTACCCCCCATATGTCCTCAGAGAGGCTGAGTGTCCCCTCCAGGCAGTC
ATGGGCCCTGAGGCCCCTCCTGCCTGGCCCTGCTCCCCAGTGGGGAGGTGACTGTGTTTCCCAG
AGTGTGAGCCGCTCTCCTCCCCCTAAAAAGCTGACTCACTGTGAGTGACCTTGGGCAAGTTCCC
AAACCTCCTTGTGCCTCAGTTTCCCCATCTGGAAAAAATGGGGCCACCTCTTGCCAGCAGTAGC
AGGGCTGCCCACGCCCCTTTCTCCCCATGCCCCATCCAGCACTTGGGCGACTCATGCCTCTGCC
TCAGTGGGCCTGTGGGAGCCTACTGGAGCCCAGCACTTACTCCCCCTGAGCAGCGAGCCTGCGT
CTGTCTCAGCTGTCCAGCGCTGAGGGCCAGGGTCTTGTGCTGTGGGGCTGGGGGATGCCCTCTT
TTCTATATTTATTTCATAGAAAGTCTCCTGCGGGAGCGGAAATGCAGTCCGGCCTAGGGCTCCC
AGCCCTTGACTGTCCTCCTGTGAGGGCCTGAAGCTGGGCCAGGGCCCGTCGCAGCGGAGCCCCC
TCTCAGCAGCCCACCGGGTCCCTCCAGGCTGCTGCCCGTGCGTGGTCTTTCTCCTCCTTTTCAA
AGCAATAGCCGCCGGGTCTGCAAAGCCCTGTCAGACAGACTGGGCCCTTCCAAGGTCAAGCCAT
GTGTCTGATGACATTCCTGGTGAAGCAAAGGAGAGGAGGATGGGTCAGCCCTCACTGGGTGTCA
CACACTGAGAGAAGTCCTATTGTAAAGAAACGGAAAAAGTCACAAAAAAGTTTGTATAAAGACA
TATTTTTGTACTACATGGGGACTCTTCCTGCATGTCAGCAATAAAACTTCCTGATCTGGAA

hide sequence

RefSeq Acc Id:

NM_032017 ⟹ NP_114406

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	36,339,628 - 36,385,924 (-)	NCBI
GRCh37	1	36,805,225 - 36,851,525 (-)	NCBI
Build 36	1	36,577,812 - 36,624,072 (-)	NCBI Archive
Celera	1	35,080,354 - 35,126,619 (-)	RGD
HuRef	1	34,921,980 - 34,968,175 (-)	NCBI
CHM1_1	1	36,921,394 - 36,967,705 (-)	NCBI
T2T-CHM13v2.0	1	36,202,501 - 36,248,808 (-)	NCBI

Sequence:

show sequence

ACTTCCGTTGTCAGGTGGCGGCGCCGCAGCCATGGAGGGAGGCGGCGGCGGCGGCGGCGGCGGC
TCGGGTGGCTGCGCTGGGAGGCGGCGGTGAGAGGCTCGCACGCCTCCAGCCCGGCCCCGGCCCC
CCGGGAGGGAGAGCCGAGCAGCCCCGGCTCTGGGCTACGGACTATGGGCGAATAGCTCTGACCA
CCCGGCGAAGTGCACACACCCAGAAGCTATGTCCTTCGGCAGTAAAAGTTTTACAGCACAATAT
ATGTGCTCTGCTCTCCTCCCGCAATCCTGCTCCAAGAGATCTTAAGCTGGAGGCACCAGGTCTG
AATTCCAGACTCCTCCCCACCACCCACACTTCACCTCCAACTGGAGCATGACCACAGACCCATT
CAGGGAGGCTGGCGGACTCTTCATCCTGGACAGTCCCTTACTGTATGTCAAGTAGAGCTGAGAA
TGAAGCGGAGAGCATCAGACAGAGGAGCTGGGGAAACGTCGGCCAGGGCCAAGGCTCTAGGAAG
TGGGATTTCTGGAAATAATGCAAAGAGAGCTGGACCATTCATCCTTGGTCCCCGTCTGGGCAAC
TCACCGGTGCCAAGCATAGTGCAGTGTTTGGCGAGGAAAGATGGCACGGATGACTTCTATCAGC
TGAAGATCCTGACCCTGGAGGAGAGGGGGGACCAAGGCATAGAGAGCCAGGAAGAGCGGCAGGG
CAAGATGCTGCTGCACACCGAGTACTCACTGCTGTCTCTCCTGCACACGCAGGATGGCGTGGTG
CACCACCACGGCCTCTTCCAGGACCGCACCTGTGAAATCGTTGAGGACACAGAATCCAGCCGGA
TGGTTAAGAAGATGAAGAAGCGCATCTGCCTCGTCCTGGACTGCCTCTGTGCTCATGACTTCAG
CGATAAGACCGCTGACCTCATCAACCTGCAGCACTACGTCATCAAGGAGAAGAGGCTCAGCGAG
AGGGAGACTGTGGTAATCTTCTACGACGTGGTCCGCGTGGTGGAGGCCCTGCACCAGAAAAATA
TCGTGCACAGAGACCTGAAGCTGGGGAACATGGTGCTCAACAAGAGGACACATCGGATAACCAT
CACCAACTTCTGCCTCGGGAAGCATCTGGTGAGCGAGGGGGACCTGCTGAAGGACCAGAGAGGG
AGCCCTGCCTACATCAGTCCCGACGTGCTCAGCGGCCGGCCGTACCGTGGCAAGCCCAGTGACA
TGTGGGCCCTGGGCGTGGTGCTCTTCACCATGCTGTATGGCCAGTTCCCCTTCTACGACAGCAT
CCCGCAGGAGCTCTTCCGCAAGATCAAGGCTGCCGAGTATACCATTCCTGAGGATGGACGGGTT
TCTGAGAACACCGTGTGTCTCATCCGGAAGCTGCTGGTCCTTGACCCCCAGCAGCGCCTGGCCG
CCGCCGACGTCCTGGAGGCCCTCAGTGCCATCATTGCATCATGGCAGTCCCTGTCATCTCTGAG
TGGGCCTTTGCAAGTGGTTCCTGACATTGATGACCAAATGAGCAATGCGGATAGCTCCCAGGAG
GCGAAGGTGACGGAGGAGTGCTCCCAGTACGAGTTTGAGAACTACATGCGTCAGCAGCTGCTGC
TGGCCGAGGAGAAGAGCTCCATCCATGACGCCCGGAGCTGGGTACCCAAGCGGCAGTTCGGCAG
CGCACCACCGGTGCGACGGCTGGGCCACGACGCACAGCCCATGACCTCCTTGGACACGGCCATC
CTGGCGCAGCGCTACCTGCGGAAATAACAGCCTCAGCCGGGGCCACCAGCACTGCTGCCACTTC
TTCCAGCCCCAGCCAAAGGCGTGGCTGTCAGGGCTGGGCCCTGTAGTGCTGGACTCTCCCGGGC
CACAATAGGGACAGGGCAGGGACAGGGACAGCCCAGGTCACACGTGGGGTCAGCAGAGGTACCA
CGAAGCTACCTTTTGGGATGATTGCTCGATTGTTTGGTTTTTAAATCTGAGAAGCCTAGATAAC
TAATCTGCTTTTAATCACGATGTTTTAATCTACCTCTGTCTCTTTAACCATGCTGTCTCTGGAC
TGAGCAAGAGGGAGGAGGGAGCCTGCTCACCCCACTCCAGGGCCTTCCCCAGCGGCCACCAACT
GACCTGGGGCGCTGCTCCCCACAGTCCAAATAAGCTGAAAGTGCAGCTCGCTGCAGGCCCCAGA
GCGAGCTTCCCCTCCTCCCTGCTCTCCCAGGCCCCTGCCACAGCCTCTTTCCGTCCCTCTCTTT
CTGATCCAGGCCCCTCAGTCCAAGCTTTGGAAAACCTTCACCTCATCTTAAACCGAACTCAAAT
ATATTTATTTTTTTACCATACCAACTTCTCTCCCATCTCTAGGTGGCTCAGTCCATGGCCACTC
CCTGCCCCCAGCCTGGCTGGACAGCAAGGAATCCACAGCCCACACGTGAGCTCCCTCCTCACCC
CCAGGCAGGGAAGCCCCTCCTGCCAGTCCCTGTCCCCTTTCAGCCCACCAGTCCCTCTCTGCTG
CCGGTGATGGGAGGCCTTTCTAGACCTGGCTCTTTCTCTCCCGTCTCAGTGGCTTCTCTGAGGT
GCTGTACACGCGCGTTAACCTGTTCCCTTCTCTATCCTTCCCCGTGGTACTGAGCTCACGTGGA
CTCCCAGTGCGAAGGGGCCCATGGGTTGGGCTGCAGGCCTGGCCGTGAGCGGGGGCTGCCTGCA
CGCTCCCCTAGCCTACTCTTGTGTTTAGGGGATGGTGGGAACATATCCCAGTGCCCTTGCCTCA
TAATAGATGTGGTGACTCTCCCGGTAGACCCTAGCAAGGGTCCTCCATGGTGGTGAGGGACTCA
GGAGAATTGTAGGGATTGGGGGACCCTGCCTGCCTGGCTTGAGAACAGCCCTGCTGCCCTTTTG
AGCCGAGATTTTGAAGTGGATGCCCGTCTTGCCAGAAATGCTGTTCTCACCAGAATGCCCCCTC
CCCTTGCCCTTACTGGACTTGGCCCTGCCTGATGCCAAGCAAAGACCCTTCCCCAGAGGCCTAC
CCCCCATATGTCCTCAGAGAGGCTGAGTGTCCCCTCCAGGCAGTCATGGGCCCTGAGGCCCCTC
CTGCCTGGCCCTGCTCCCCAGTGGGGAGGTGACTGTGTTTCCCAGAGTGTGAGCCGCTCTCCTC
CCCCTAAAAAGCTGACTCACTGTGAGTGACCTTGGGCAAGTTCCCAAACCTCCTTGTGCCTCAG
TTTCCCCATCTGGAAAAAATGGGGCCACCTCTTGCCAGCAGTAGCAGGGCTGCCCACGCCCCTT
TCTCCCCATGCCCCATCCAGCACTTGGGCGACTCATGCCTCTGCCTCAGTGGGCCTGTGGGAGC
CTACTGGAGCCCAGCACTTACTCCCCCTGAGCAGCGAGCCTGCGTCTGTCTCAGCTGTCCAGCG
CTGAGGGCCAGGGTCTTGTGCTGTGGGGCTGGGGGATGCCCTCTTTTCTATATTTATTTCATAG
AAAGTCTCCTGCGGGAGCGGAAATGCAGTCCGGCCTAGGGCTCCCAGCCCTTGACTGTCCTCCT
GTGAGGGCCTGAAGCTGGGCCAGGGCCCGTCGCAGCGGAGCCCCCTCTCAGCAGCCCACCGGGT
CCCTCCAGGCTGCTGCCCGTGCGTGGTCTTTCTCCTCCTTTTCAAAGCAATAGCCGCCGGGTCT
GCAAAGCCCTGTCAGACAGACTGGGCCCTTCCAAGGTCAAGCCATGTGTCTGATGACATTCCTG
GTGAAGCAAAGGAGAGGAGGATGGGTCAGCCCTCACTGGGTGTCACACACTGAGAGAAGTCCTA
TTGTAAAGAAACGGAAAAAGTCACAAAAAAGTTTGTATAAAGACATATTTTTGTACTACATGGG
GACTCTTCCTGCATGTCAGCAATAAAACTTCCTGATCTGGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001269475	(Get FASTA)	NCBI Sequence Viewer
	NP_001269476	(Get FASTA)	NCBI Sequence Viewer
	NP_114406	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH05169	(Get FASTA)	NCBI Sequence Viewer
	AAH07835	(Get FASTA)	NCBI Sequence Viewer
	AAH08344	(Get FASTA)	NCBI Sequence Viewer
	AAP20040	(Get FASTA)	NCBI Sequence Viewer
	BAB15794	(Get FASTA)	NCBI Sequence Viewer
	BAC11361	(Get FASTA)	NCBI Sequence Viewer
	BAC11371	(Get FASTA)	NCBI Sequence Viewer
	BAD18694	(Get FASTA)	NCBI Sequence Viewer
	CAD38852	(Get FASTA)	NCBI Sequence Viewer
	CAH05590	(Get FASTA)	NCBI Sequence Viewer
	CAH05591	(Get FASTA)	NCBI Sequence Viewer
	EAX07368	(Get FASTA)	NCBI Sequence Viewer
	EAX07369	(Get FASTA)	NCBI Sequence Viewer
	EAX07370	(Get FASTA)	NCBI Sequence Viewer
	EAX07371	(Get FASTA)	NCBI Sequence Viewer
	EAX07372	(Get FASTA)	NCBI Sequence Viewer
	EAX07373	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000352245.2
	ENSP00000362221
	ENSP00000362221.3
	ENSP00000362222
	ENSP00000362222.3
	ENSP00000362224
	ENSP00000362224.4
GenBank Protein	Q8N2I9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_114406 ⟸ NM_032017
- Peptide Label:	isoform 2
- UniProtKB:	Q9BSA3 (UniProtKB/Swiss-Prot), Q96I44 (UniProtKB/Swiss-Prot), Q96HN6 (UniProtKB/Swiss-Prot), Q8N3I6 (UniProtKB/Swiss-Prot), Q8N2J8 (UniProtKB/Swiss-Prot), Q6ZMN1 (UniProtKB/Swiss-Prot), Q5VTK9 (UniProtKB/Swiss-Prot), Q5VTK8 (UniProtKB/Swiss-Prot), D3DPS8 (UniProtKB/Swiss-Prot), Q9H7H6 (UniProtKB/Swiss-Prot), Q8N2I9 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQ LKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSR MVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKN IVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSD MWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLA AADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLL LAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK hide sequence

RefSeq Acc Id:	NP_001269476 ⟸ NM_001282547
- Peptide Label:	isoform 2
- UniProtKB:	Q9BSA3 (UniProtKB/Swiss-Prot), Q96I44 (UniProtKB/Swiss-Prot), Q96HN6 (UniProtKB/Swiss-Prot), Q8N3I6 (UniProtKB/Swiss-Prot), Q8N2J8 (UniProtKB/Swiss-Prot), Q6ZMN1 (UniProtKB/Swiss-Prot), Q5VTK9 (UniProtKB/Swiss-Prot), Q5VTK8 (UniProtKB/Swiss-Prot), D3DPS8 (UniProtKB/Swiss-Prot), Q9H7H6 (UniProtKB/Swiss-Prot), Q8N2I9 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQ LKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSR MVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKN IVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSD MWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLA AADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLL LAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK hide sequence

RefSeq Acc Id:	NP_001269475 ⟸ NM_001282546
- Peptide Label:	isoform 1
- UniProtKB:	Q8N2I9 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILALCAVGPRLGNSPVPSIVQCLARKDGT DDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVED TESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEA LHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYR GKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDP QQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYM RQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK hide sequence

RefSeq Acc Id:

ENSP00000352245 ⟸ ENST00000359297

RefSeq Acc Id:

ENSP00000362221 ⟸ ENST00000373129

RefSeq Acc Id:

ENSP00000362222 ⟸ ENST00000373130

RefSeq Acc Id:

ENSP00000362224 ⟸ ENST00000373132

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8N2I9-F1-model_v2	AlphaFold	Q8N2I9	1-435	view protein structure

Promoters

RGD ID:

6854984

Promoter ID:

EPDNEW_H657

Type:

single initiation site

Name:

STK40_3

Description:

serine/threonine kinase 40

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H658 EPDNEW_H659

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	36,369,826 - 36,369,886	EPDNEW

RGD ID:

6854986

Promoter ID:

EPDNEW_H658

Type:

initiation region

Name:

STK40_1

Description:

serine/threonine kinase 40

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H657 EPDNEW_H659

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	36,385,915 - 36,385,975	EPDNEW

RGD ID:

6854988

Promoter ID:

EPDNEW_H659

Type:

initiation region

Name:

STK40_2

Description:

serine/threonine kinase 40

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H657 EPDNEW_H658

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	36,386,531 - 36,386,591	EPDNEW

RGD ID:

6786941

Promoter ID:

HG_KWN:2017

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

K562

Transcripts:

ENST00000359297

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	1	36,599,546 - 36,600,046 (-)	MPROMDB

RGD ID:

6786943

Promoter ID:

HG_KWN:2019

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, Lymphoblastoid

Transcripts:

OTTHUMT00000022768

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	1	36,604,369 - 36,604,869 (-)	MPROMDB

RGD ID:

6786961

Promoter ID:

HG_KWN:2020

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, Jurkat, K562, Lymphoblastoid, NB4

Transcripts:

ENST00000373130, NM_032017, OTTHUMT00000022595, OTTHUMT00000022767, OTTHUMT00000022948, UC009VVA.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	1	36,623,826 - 36,625,052 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:21373	AgrOrtholog
COSMIC	STK40	COSMIC
Ensembl Genes	ENSG00000196182	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000359297.6	UniProtKB/Swiss-Prot
	ENST00000373129	ENTREZGENE
	ENST00000373129.7	UniProtKB/Swiss-Prot
	ENST00000373130	ENTREZGENE
	ENST00000373130.7	UniProtKB/Swiss-Prot
	ENST00000373132	ENTREZGENE
	ENST00000373132.4	UniProtKB/Swiss-Prot
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
GTEx	ENSG00000196182	GTEx
HGNC ID	HGNC:21373	ENTREZGENE
Human Proteome Map	STK40	Human Proteome Map
InterPro	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Ser/Thr_kinase_40	UniProtKB/Swiss-Prot
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot
	Tribbles/Ser_Thr_kinase_40	UniProtKB/Swiss-Prot
KEGG Report	hsa:83931	UniProtKB/Swiss-Prot
NCBI Gene	83931	ENTREZGENE
OMIM	609437	OMIM
PANTHER	PTHR22961	UniProtKB/Swiss-Prot
	SERINE/THREONINE-PROTEIN KINASE 40	UniProtKB/Swiss-Prot
Pfam	Pkinase	UniProtKB/Swiss-Prot
PharmGKB	PA142670860	PharmGKB
PROSITE	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot
SMART	S_TKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot
UniProt	D3DPS8	ENTREZGENE
	Q5VTK8	ENTREZGENE
	Q5VTK9	ENTREZGENE
	Q6ZMN1	ENTREZGENE
	Q8N2I9	ENTREZGENE
	Q8N2J8	ENTREZGENE
	Q8N3I6	ENTREZGENE
	Q96HN6	ENTREZGENE
	Q96I44	ENTREZGENE
	Q9BSA3	ENTREZGENE
	Q9H7H6	ENTREZGENE
	STK40_HUMAN	UniProtKB/Swiss-Prot
UniProt Secondary	D3DPS8	UniProtKB/Swiss-Prot
	Q5VTK8	UniProtKB/Swiss-Prot
	Q5VTK9	UniProtKB/Swiss-Prot
	Q6ZMN1	UniProtKB/Swiss-Prot
	Q8N2J8	UniProtKB/Swiss-Prot
	Q8N3I6	UniProtKB/Swiss-Prot
	Q96HN6	UniProtKB/Swiss-Prot
	Q96I44	UniProtKB/Swiss-Prot
	Q9BSA3	UniProtKB/Swiss-Prot
	Q9H7H6	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar