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Gene: TYW5 (tRNA-yW synthesizing protein 5) Homo sapiens
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Symbol: TYW5
Name: tRNA-yW synthesizing protein 5
Description: Exhibits several functions, including iron ion binding activity; protein homodimerization activity; and tRNA binding activity. Involved in wybutosine biosynthetic process. Predicted to localize to the cytoplasm; INTERACTS WITH 2-hydroxypropanoic acid; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C2orf60; FLJ37953; hTYW5; jmjC domain-containing protein; jmjC domain-containing protein C2orf60; MGC70509; tRNA wybutosine-synthesizing protein 5; tRNA yW-synthesizing enzyme 5; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase
Orthologs:
Mus musculus (house mouse) : Tyw5 (tRNA-yW synthesizing protein 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tyw5 (tRNA-yW synthesizing protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tyw5 (tRNA-yW synthesizing protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : TYW5 (tRNA-yW synthesizing protein 5)
Canis lupus familiaris (dog) : TYW5 (tRNA-yW synthesizing protein 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tyw5 (tRNA-yW synthesizing protein 5)
Sus scrofa (pig) : TYW5 (tRNA-yW synthesizing protein 5)
Chlorocebus sabaeus (green monkey) : TYW5 (tRNA-yW synthesizing protein 5)
Heterocephalus glaber (naked mole-rat) : Tyw5 (tRNA-yW synthesizing protein 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2199,928,913 - 199,955,736 (-)Ensembl
GRCh382199,928,913 - 199,955,624 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372200,793,634 - 200,820,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362200,501,879 - 200,528,468 (-)NCBINCBI36hg18NCBI36
Celera2194,548,334 - 194,575,163 (-)NCBI
Cytogenetic Map2q33.1NCBI
HuRef2192,646,316 - 192,673,173 (-)NCBIHuRef
CHM1_12200,799,759 - 200,826,590 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TYW5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604998
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.