Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | Gtf2ird2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of GTF2IRD2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Gtf2ird2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of GTF2IRD2 mRNA] | CTD | PMID:22206623 | 15-acetyldeoxynivalenol | increases expression | EXP | | 6480464 | 15-acetyldeoxynivalenol results in increased expression of GTF2IRD2 mRNA | CTD | PMID:23792671 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Gtf2ird2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GTF2IRD2 mRNA | CTD | PMID:21570461 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GTF2IRD2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | affects expression | ISO | Gtf2ird2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of GTF2IRD2 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Gtf2ird2 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of GTF2IRD2 exon | CTD | PMID:33297965 | 6-propyl-2-thiouracil | decreases expression | ISO | Gtf2ird2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:30047161 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of GTF2IRD2 mRNA | CTD | PMID:32763439 | amitrole | decreases expression | ISO | Gtf2ird2 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:30047161 | amphetamine | decreases expression | ISO | Gtf2ird2 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:30779732 | aristolochic acid A | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of GTF2IRD2 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:32234424 | bisphenol A | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:36232920 | bisphenol A | decreases expression | ISO | Gtf2ird2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol F | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:28628672 | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:26079696 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GTF2IRD2 gene] | CTD | PMID:28238834 | clofibrate | decreases expression | ISO | Gtf2ird2 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:17585979 | copper atom | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of GTF2IRD2 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of GTF2IRD2 mRNA | CTD | PMID:20971185 | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GTF2IRD2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:28628672 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | entinostat | decreases expression | EXP | | 6480464 | entinostat results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:27188386 | fipronil | decreases expression | ISO | Gtf2ird2 (Rattus norvegicus) | 6480464 | fipronil results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:34044035 | folic acid | multiple interactions | ISO | Gtf2ird2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of GTF2IRD2 mRNA] | CTD | PMID:22206623 | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GTF2IRD2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:28628672 | methimazole | decreases expression | ISO | Gtf2ird2 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:30047161 | pentanal | decreases expression | EXP | | 6480464 | pentanal results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:26079696 | pirinixic acid | decreases expression | ISO | Gtf2ird2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:23811191 | propanal | decreases expression | EXP | | 6480464 | propionaldehyde results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:26079696 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:23557933 | rifampicin | increases expression | EXP | | 6480464 | Rifampin results in increased expression of GTF2IRD2 mRNA | CTD | PMID:24552687 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide analog results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | Gtf2ird2 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of GTF2IRD2 mRNA | CTD | PMID:16014739 | sotorasib | multiple interactions | EXP | | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:36139627 | sulfadimethoxine | decreases expression | ISO | Gtf2ird2 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:30047161 | trametinib | multiple interactions | EXP | | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of GTF2IRD2 mRNA | CTD | PMID:36139627 | trichostatin A | decreases expression | EXP | | 6480464 | trichostatin A results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:27188386 | tungsten | decreases expression | ISO | Gtf2ird2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:30912803 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | EXP | | 6480464 | vorinostat results in decreased expression of GTF2IRD2 mRNA | CTD | PMID:27188386 | |