PLPPR5 (phospholipid phosphatase related 5) - Rat Genome Database

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Gene: PLPPR5 (phospholipid phosphatase related 5) Homo sapiens
Analyze
Symbol: PLPPR5
Name: phospholipid phosphatase related 5
RGD ID: 1604517
HGNC Page HGNC:31703
Description: Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in several processes, including phospholipid dephosphorylation; phospholipid metabolic process; and positive regulation of cell projection organization. Predicted to be located in membrane. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: lipid phosphate phosphatase-related protein type 5; LPPR5; PAP2; PAP2D; phosphatidic acid phosphatase 2d; phosphatidic acid phosphatase type 2; phosphatidic acid phosphatase type 2d; phospholipid phosphatase-related protein type 5; plasticity-related gene 5 protein; plasticity-related protein 5; PRG-5; PRG5
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38198,890,245 - 99,005,786 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl198,890,245 - 99,227,929 (-)EnsemblGRCh38hg38GRCh38
GRCh37199,355,801 - 99,470,417 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,128,389 - 99,243,037 (-)NCBINCBI36Build 36hg18NCBI36
Celera197,609,711 - 97,724,382 (-)NCBICelera
Cytogenetic Map1p21.3NCBI
HuRef197,478,911 - 97,593,593 (-)NCBIHuRef
CHM1_1199,471,965 - 99,586,821 (-)NCBICHM1_1
T2T-CHM13v2.0198,738,338 - 98,856,692 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8619474   PMID:9110174   PMID:12477932   PMID:16010976   PMID:20032306   PMID:20379614   PMID:21873635   PMID:23064961   PMID:23251661   PMID:23259602   PMID:24903457  


Genomics

Comparative Map Data
PLPPR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38198,890,245 - 99,005,786 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl198,890,245 - 99,227,929 (-)EnsemblGRCh38hg38GRCh38
GRCh37199,355,801 - 99,470,417 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,128,389 - 99,243,037 (-)NCBINCBI36Build 36hg18NCBI36
Celera197,609,711 - 97,724,382 (-)NCBICelera
Cytogenetic Map1p21.3NCBI
HuRef197,478,911 - 97,593,593 (-)NCBIHuRef
CHM1_1199,471,965 - 99,586,821 (-)NCBICHM1_1
T2T-CHM13v2.0198,738,338 - 98,856,692 (-)NCBIT2T-CHM13v2.0
Plppr5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393117,368,274 - 117,483,157 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3117,278,733 - 117,483,156 (+)EnsemblGRCm39 Ensembl
GRCm383117,574,608 - 117,689,508 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3117,485,084 - 117,689,507 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl3117,574,836 - 117,689,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv373117,278,379 - 117,392,424 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363117,567,604 - 117,681,484 (+)NCBIMGSCv36mm8
Celera3123,988,384 - 124,102,194 (+)NCBICelera
Cytogenetic Map3G1NCBI
cM Map351.21NCBI
Plppr5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82208,143,058 - 208,422,836 (+)NCBIGRCr8
mRatBN7.22205,525,466 - 205,737,892 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2205,458,176 - 205,717,599 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2213,261,966 - 213,372,801 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02211,174,691 - 211,280,207 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02205,995,017 - 206,105,847 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02219,895,141 - 220,102,333 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2219,896,765 - 220,101,791 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02237,965,738 - 238,028,143 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02238,156,053 - 238,169,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42213,925,783 - 214,036,361 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12213,889,370 - 213,998,511 (+)NCBI
Celera2198,085,140 - 198,195,375 (+)NCBICelera
Cytogenetic Map2q42NCBI
Plppr5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554353,699,744 - 3,773,286 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554353,700,217 - 3,818,532 (-)NCBIChiLan1.0ChiLan1.0
PLPPR5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21128,024,674 - 128,136,435 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11127,179,285 - 127,291,002 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01101,547,329 - 101,661,187 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11100,268,826 - 100,382,272 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1100,268,826 - 100,385,980 (-)Ensemblpanpan1.1panPan2
PLPPR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1650,823,227 - 50,931,525 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl650,754,798 - 50,929,224 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha653,489,185 - 53,615,405 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0651,159,734 - 51,284,974 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl651,160,811 - 51,284,959 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1650,852,156 - 50,976,186 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0650,831,450 - 50,957,167 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0651,265,386 - 51,389,370 (+)NCBIUU_Cfam_GSD_1.0
Plppr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058108,115,914 - 108,224,980 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936537723,386 - 832,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936537723,390 - 829,991 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLPPR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4118,947,440 - 119,065,184 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14118,600,361 - 119,065,669 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24130,548,600 - 130,666,258 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLPPR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12034,079,224 - 34,419,122 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2034,302,819 - 34,419,051 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660351,889,870 - 2,007,662 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plppr5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248571,558,182 - 1,671,110 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248571,558,305 - 1,671,577 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLPPR5
16 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001010861.2(LPPR5):c.919-7768T>C single nucleotide variant Lung cancer [RCV000091059] Chr1:98900872 [GRCh38]
Chr1:99366428 [GRCh37]
Chr1:1p21.3
uncertain significance
NM_001010861.2(LPPR5):c.621+1539A>G single nucleotide variant Lung cancer [RCV000091060] Chr1:98951531 [GRCh38]
Chr1:99417087 [GRCh37]
Chr1:1p21.3
uncertain significance
GRCh38/hg38 1p21.3-13.3(chr1:97272349-108893138)x1 copy number loss See cases [RCV000135333] Chr1:97272349..108893138 [GRCh38]
Chr1:97737905..109435760 [GRCh37]
Chr1:97510493..109237283 [NCBI36]
Chr1:1p21.3-13.3
pathogenic
GRCh38/hg38 1p31.1-21.1(chr1:83457325-104273917)x3 copy number gain See cases [RCV000135654] Chr1:83457325..104273917 [GRCh38]
Chr1:83923008..104816539 [GRCh37]
Chr1:83695596..104618062 [NCBI36]
Chr1:1p31.1-21.1
pathogenic
GRCh38/hg38 1p21.3(chr1:96124445-99094525)x1 copy number loss See cases [RCV000137528] Chr1:96124445..99094525 [GRCh38]
Chr1:96590001..99560081 [GRCh37]
Chr1:96362589..99332669 [NCBI36]
Chr1:1p21.3
uncertain significance
GRCh38/hg38 1p21.3(chr1:98477261-99235028)x1 copy number loss See cases [RCV000139228] Chr1:98477261..99235028 [GRCh38]
Chr1:98942817..99700584 [GRCh37]
Chr1:98715405..99473172 [NCBI36]
Chr1:1p21.3
uncertain significance
GRCh38/hg38 1p21.3(chr1:98603715-99120960)x1 copy number loss See cases [RCV000141710] Chr1:98603715..99120960 [GRCh38]
Chr1:99069271..99586516 [GRCh37]
Chr1:98841859..99359104 [NCBI36]
Chr1:1p21.3
uncertain significance
GRCh38/hg38 1p31.1-13.3(chr1:72661709-107456880)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051825]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051825]|See cases [RCV000051825] Chr1:72661709..107456880 [GRCh38]
Chr1:73127392..107999502 [GRCh37]
Chr1:72899980..107801025 [NCBI36]
Chr1:1p31.1-13.3
pathogenic
GRCh38/hg38 1p21.3-13.3(chr1:97410602-110670510)x1 copy number loss See cases [RCV000053877] Chr1:97410602..110670510 [GRCh38]
Chr1:97876158..111213132 [GRCh37]
Chr1:97648746..111014655 [NCBI36]
Chr1:1p21.3-13.3
pathogenic
GRCh38/hg38 1p21.3-13.3(chr1:98557000-107949047)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053878]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053878]|See cases [RCV000053878] Chr1:98557000..107949047 [GRCh38]
Chr1:99022556..108491669 [GRCh37]
Chr1:98795144..108293192 [NCBI36]
Chr1:1p21.3-13.3
pathogenic
NM_001037317.2(PLPPR5):c.202C>T (p.Leu68Phe) single nucleotide variant Inborn genetic diseases [RCV003275962] Chr1:99004470 [GRCh38]
Chr1:99470026 [GRCh37]
Chr1:1p21.3
uncertain significance
NM_001037317.2(PLPPR5):c.217G>T (p.Ala73Ser) single nucleotide variant Inborn genetic diseases [RCV002685343] Chr1:99004455 [GRCh38]
Chr1:99470011 [GRCh37]
Chr1:1p21.3
uncertain significance
NM_001037317.2(PLPPR5):c.624G>A (p.Met208Ile) single nucleotide variant Inborn genetic diseases [RCV002874942] Chr1:98922056 [GRCh38]
Chr1:99387612 [GRCh37]
Chr1:1p21.3
uncertain significance
NM_001037317.2(PLPPR5):c.14C>T (p.Pro5Leu) single nucleotide variant Inborn genetic diseases [RCV002769895] Chr1:99004658 [GRCh38]
Chr1:99470214 [GRCh37]
Chr1:1p21.3
uncertain significance
NM_001037317.2(PLPPR5):c.362G>A (p.Arg121Gln) single nucleotide variant Inborn genetic diseases [RCV003265789] Chr1:98956617 [GRCh38]
Chr1:99422173 [GRCh37]
Chr1:1p21.3
uncertain significance
NM_001037317.2(PLPPR5):c.334A>G (p.Ile112Val) single nucleotide variant Inborn genetic diseases [RCV003367239] Chr1:98956645 [GRCh38]
Chr1:99422201 [GRCh37]
Chr1:1p21.3
uncertain significance
NM_001037317.2(PLPPR5):c.784A>G (p.Ile262Val) single nucleotide variant Inborn genetic diseases [RCV003370814] Chr1:98921896 [GRCh38]
Chr1:99387452 [GRCh37]
Chr1:1p21.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2477
Count of miRNA genes:761
Interacting mature miRNAs:902
Transcripts:ENST00000263177, ENST00000370188, ENST00000534652
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
AL009347  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37199,394,395 - 99,394,596UniSTSGRCh37
Build 36199,166,983 - 99,167,184RGDNCBI36
Celera197,648,309 - 97,648,510RGD
Cytogenetic Map1p21.3UniSTS
HuRef197,517,536 - 97,517,737UniSTS
RH79763  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37199,376,495 - 99,376,709UniSTSGRCh37
Build 36199,149,083 - 99,149,297RGDNCBI36
Celera197,630,409 - 97,630,623RGD
Cytogenetic Map1p21.3UniSTS
HuRef197,499,614 - 97,499,828UniSTS
RH36855  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37199,355,936 - 99,356,123UniSTSGRCh37
Build 36199,128,524 - 99,128,711RGDNCBI36
Celera197,609,846 - 97,610,033RGD
Cytogenetic Map1p21.3UniSTS
HuRef197,479,046 - 97,479,233UniSTS
RH64658  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37199,387,461 - 99,387,600UniSTSGRCh37
Build 36199,160,049 - 99,160,188RGDNCBI36
Celera197,641,375 - 97,641,514RGD
Cytogenetic Map1p21.3UniSTS
HuRef197,510,591 - 97,510,730UniSTS
GeneMap99-GB4 RH Map1282.77UniSTS
NCBI RH Map1652.0UniSTS
STS-T87228  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37199,355,853 - 99,356,086UniSTSGRCh37
Build 36199,128,441 - 99,128,674RGDNCBI36
Celera197,609,763 - 97,609,996RGD
Cytogenetic Map1p21.3UniSTS
HuRef197,478,963 - 97,479,196UniSTS
GeneMap99-GB4 RH Map1270.31UniSTS
SHGC-75188  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1p21.3UniSTS
TNG Radiation Hybrid Map154438.0UniSTS
GeneMap99-GB4 RH Map1270.85UniSTS
NCBI RH Map1652.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 2 2 238 24 2 6
Low 229 5 84 7 23 7 235 15 2405 100 415 67 5 1 17
Below cutoff 1470 616 499 84 255 41 1818 1136 906 137 382 521 46 351 1208 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001010861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001037317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011540836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011540837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011540838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF131783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK295688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL161744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL445433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL590110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY574039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY634620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF514931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DR001828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ472844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  R37934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000263177   ⟹   ENSP00000263177
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl198,890,245 - 99,004,861 (-)Ensembl
RefSeq Acc Id: ENST00000370188   ⟹   ENSP00000359207
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl198,890,245 - 99,005,032 (-)Ensembl
RefSeq Acc Id: ENST00000534652
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl198,990,856 - 99,004,484 (-)Ensembl
RefSeq Acc Id: ENST00000672681   ⟹   ENSP00000500930
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl198,890,245 - 99,005,032 (-)Ensembl
RefSeq Acc Id: ENST00000696571   ⟹   ENSP00000512726
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl198,890,245 - 99,227,929 (-)Ensembl
RefSeq Acc Id: NM_001010861   ⟹   NP_001010861
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38198,890,245 - 99,004,861 (-)NCBI
GRCh37199,355,801 - 99,470,449 (-)RGD
Build 36199,128,389 - 99,243,037 (-)NCBI Archive
Celera197,609,711 - 97,724,382 (-)RGD
HuRef197,478,911 - 97,593,593 (-)ENTREZGENE
CHM1_1199,471,965 - 99,586,821 (-)NCBI
T2T-CHM13v2.0198,738,338 - 98,853,006 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001037317   ⟹   NP_001032394
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38198,890,245 - 99,004,861 (-)NCBI
GRCh37199,355,801 - 99,470,449 (-)RGD
Build 36199,128,389 - 99,243,037 (-)NCBI Archive
Celera197,609,711 - 97,724,382 (-)RGD
HuRef197,478,911 - 97,593,593 (-)ENTREZGENE
CHM1_1199,471,965 - 99,586,821 (-)NCBI
T2T-CHM13v2.0198,738,338 - 98,853,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011540838   ⟹   XP_011539140
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38198,890,245 - 99,005,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054334713   ⟹   XP_054190688
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0198,738,338 - 98,856,692 (-)NCBI
RefSeq Acc Id: NP_001010861   ⟸   NM_001010861
- Peptide Label: isoform 2
- UniProtKB: B4DIM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001032394   ⟸   NM_001037317
- Peptide Label: isoform 1
- UniProtKB: Q32ZD0 (UniProtKB/Swiss-Prot),   B7UCH3 (UniProtKB/Swiss-Prot),   A8MPX4 (UniProtKB/Swiss-Prot),   Q3ZCU7 (UniProtKB/Swiss-Prot),   Q32ZL2 (UniProtKB/Swiss-Prot),   B4DIM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011539140   ⟸   XM_011540838
- Peptide Label: isoform X1
- UniProtKB: B4DIM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000359207   ⟸   ENST00000370188
RefSeq Acc Id: ENSP00000263177   ⟸   ENST00000263177
RefSeq Acc Id: ENSP00000500930   ⟸   ENST00000672681
RefSeq Acc Id: ENSP00000512726   ⟸   ENST00000696571
RefSeq Acc Id: XP_054190688   ⟸   XM_054334713
- Peptide Label: isoform X1
- UniProtKB: B4DIM8 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q32ZL2-F1-model_v2 AlphaFold Q32ZL2 1-321 view protein structure

Promoters
RGD ID:6856314
Promoter ID:EPDNEW_H1322
Type:initiation region
Name:PLPPR5_1
Description:phospholipid phosphatase related 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1323  EPDNEW_H1324  EPDNEW_H1325  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38199,004,861 - 99,004,921EPDNEW
RGD ID:6856316
Promoter ID:EPDNEW_H1323
Type:initiation region
Name:PLPPR5_2
Description:phospholipid phosphatase related 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1322  EPDNEW_H1324  EPDNEW_H1325  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38199,005,099 - 99,005,159EPDNEW
RGD ID:6856318
Promoter ID:EPDNEW_H1324
Type:initiation region
Name:PLPPR5_4
Description:phospholipid phosphatase related 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1322  EPDNEW_H1323  EPDNEW_H1325  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38199,005,294 - 99,005,354EPDNEW
RGD ID:6856320
Promoter ID:EPDNEW_H1325
Type:initiation region
Name:PLPPR5_3
Description:phospholipid phosphatase related 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1322  EPDNEW_H1323  EPDNEW_H1324  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38199,005,786 - 99,005,846EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31703 AgrOrtholog
COSMIC PLPPR5 COSMIC
Ensembl Genes ENSG00000117598 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000263177 ENTREZGENE
  ENST00000263177.5 UniProtKB/Swiss-Prot
  ENST00000370188 ENTREZGENE
  ENST00000370188.7 UniProtKB/Swiss-Prot
  ENST00000672681.1 UniProtKB/TrEMBL
  ENST00000696571.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphatidic acid phosphatase type 2/haloperoxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000117598 GTEx
HGNC ID HGNC:31703 ENTREZGENE
Human Proteome Map PLPPR5 Human Proteome Map
InterPro P_Acid_Pase_2/haloperoxi_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLPP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:163404 UniProtKB/Swiss-Prot
NCBI Gene 163404 ENTREZGENE
OMIM 617287 OMIM
PANTHER PTHR10165 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10165:SF17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA166181599 PharmGKB
SMART acidPPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5F9ZI76_HUMAN UniProtKB/TrEMBL
  A0A8Q3SIM6_HUMAN UniProtKB/TrEMBL
  A8MPX4 ENTREZGENE
  B4DIM8 ENTREZGENE, UniProtKB/TrEMBL
  B7UCH3 ENTREZGENE
  PLPR5_HUMAN UniProtKB/Swiss-Prot
  Q32ZD0 ENTREZGENE
  Q32ZL2 ENTREZGENE
  Q3ZCU7 ENTREZGENE
UniProt Secondary A8MPX4 UniProtKB/Swiss-Prot
  B7UCH3 UniProtKB/Swiss-Prot
  Q32ZD0 UniProtKB/Swiss-Prot
  Q3ZCU7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-20 PLPPR5  phospholipid phosphatase related 5  LPPR5  lipid phosphate phosphatase-related protein type 5  Symbol and/or name change 5135510 APPROVED